JP2023516286A5 - - Google Patents

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Publication number
JP2023516286A5
JP2023516286A5 JP2022550781A JP2022550781A JP2023516286A5 JP 2023516286 A5 JP2023516286 A5 JP 2023516286A5 JP 2022550781 A JP2022550781 A JP 2022550781A JP 2022550781 A JP2022550781 A JP 2022550781A JP 2023516286 A5 JP2023516286 A5 JP 2023516286A5
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Japan
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amino acid
acid sequence
seq
domain containing
identity
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JP2022550781A
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Japanese (ja)
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JP2023516286A (ja
JP7747645B2 (ja
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Priority claimed from PCT/CN2021/078203 external-priority patent/WO2021170100A1/en
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JP2022550781A 2020-02-27 2021-02-26 グリピカン-3(gpc3)を標的化する抗体及びキメラ抗原受容体並びにその使用方法 Active JP7747645B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
CNPCT/CN2020/076937 2020-02-27
CN2020076937 2020-02-27
PCT/CN2021/078203 WO2021170100A1 (en) 2020-02-27 2021-02-26 Antibodies and chimeric antigen receptors targeting glypican-3 (gpc3) and methods of use thereof

Publications (3)

Publication Number Publication Date
JP2023516286A JP2023516286A (ja) 2023-04-19
JP2023516286A5 true JP2023516286A5 (https=) 2024-02-29
JP7747645B2 JP7747645B2 (ja) 2025-10-01

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ID=77490732

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JP2022550781A Active JP7747645B2 (ja) 2020-02-27 2021-02-26 グリピカン-3(gpc3)を標的化する抗体及びキメラ抗原受容体並びにその使用方法

Country Status (12)

Country Link
US (1) US20230088461A1 (https=)
EP (1) EP4110912A4 (https=)
JP (1) JP7747645B2 (https=)
KR (1) KR20220146456A (https=)
CN (1) CN115151639A (https=)
AU (1) AU2021225978A1 (https=)
BR (1) BR112022016958A2 (https=)
CA (1) CA3170023A1 (https=)
IL (1) IL295774A (https=)
MX (1) MX2022010360A (https=)
WO (1) WO2021170100A1 (https=)
ZA (1) ZA202209069B (https=)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20230147619A (ko) * 2021-02-26 2023-10-23 난징 레전드 바이오테크 씨오., 엘티디. 외인적으로 도입된 사이토카인을 발현하는 조작된 면역이펙터 세포
WO2024022509A1 (en) * 2022-07-29 2024-02-01 Nanjing Legend Biotech Co., Ltd. Methods for promoting persistence of cell therapy
US20260027209A1 (en) * 2022-07-29 2026-01-29 Legend Biotech Ireland Limited Claudin-6 binding moieties and uses thereof
CN117025541B (zh) * 2023-08-15 2025-10-17 福建医科大学附属协和医院 一种靶向b7-h3并共表达细胞因子和趋化因子的car-t细胞及其用途
WO2025159562A1 (ko) * 2024-01-24 2025-07-31 국립암센터 Gpc3에 특이적으로 결합하는 신규 항체 및 이의 용도

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20050020806A (ko) * 2002-05-23 2005-03-04 써니브룩 앤드 우먼스 칼리지 헬스 사이언시즈 센터 간세포암의 진단
EP1684076B1 (en) * 2003-10-29 2008-12-31 Kumamoto Technology & Industry Foundation Diagnostic method for malignant melanoma
SI1674111T1 (sl) * 2004-07-09 2011-02-28 Chugai Pharmaceutical Co Ltd Protitelo proti glipikanu 3
US7723043B2 (en) * 2006-01-04 2010-05-25 Picobella, Lp Methods for screening for prostate cancer
SG11201407972RA (en) * 2012-06-01 2015-01-29 Us Health High-affinity monoclonal antibodies to glypican-3 and use thereof
WO2015179658A2 (en) * 2014-05-22 2015-11-26 Genentech, Inc. Anti-gpc3 antibodies and immunoconjugates
JP2017529851A (ja) * 2014-09-26 2017-10-12 ベイラー カレッジ オブ メディスンBaylor College Of Medicine 養子免疫療法のためのグリピカン−3特異的キメラ抗原レセプター
ES2818103T3 (es) * 2015-01-16 2021-04-09 Juno Therapeutics Inc Anticuerpos y receptores de antígenos quiméricos específicos para ROR1
JP2019532953A (ja) * 2016-09-30 2019-11-14 ノバルティス アーゲー 増強された有効性を有する免疫エフェクター細胞治療
MX2019008221A (es) * 2017-01-10 2019-12-09 Univ Yamaguchi Anticuerpo anti-gpc3.
EP3615574A4 (en) * 2017-04-26 2021-02-24 Eureka Therapeutics, Inc. SPECIFIC GLYPICAN 3 RECOGNIZING CONSTRUCTS AND THEIR USE
CN109385400A (zh) * 2017-08-09 2019-02-26 科济生物医药(上海)有限公司 共表达pd-l1阻断剂的嵌合抗原受体修饰的免疫效应细胞
AR114112A1 (es) * 2018-02-15 2020-07-22 Seattle Genetics Inc Anticuerpos de glipicano 3 y conjugados de los mismos
WO2020017479A1 (ja) * 2018-07-17 2020-01-23 ノイルイミューン・バイオテック株式会社 抗gpc3一本鎖抗体を含むcar
CN110684120B (zh) * 2019-10-12 2023-03-07 华夏源(上海)细胞基因工程股份有限公司 一种靶向gpc3的嵌合抗原受体及其应用

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