JP2023515927A5 - - Google Patents

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Publication number
JP2023515927A5
JP2023515927A5 JP2022549759A JP2022549759A JP2023515927A5 JP 2023515927 A5 JP2023515927 A5 JP 2023515927A5 JP 2022549759 A JP2022549759 A JP 2022549759A JP 2022549759 A JP2022549759 A JP 2022549759A JP 2023515927 A5 JP2023515927 A5 JP 2023515927A5
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JP
Japan
Prior art keywords
composition according
nanoparticles
nucleic acid
cationic lipid
tumor
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2022549759A
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English (en)
Japanese (ja)
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JP2023515927A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2021/018831 external-priority patent/WO2021168290A1/en
Publication of JP2023515927A publication Critical patent/JP2023515927A/ja
Publication of JP2023515927A5 publication Critical patent/JP2023515927A5/ja
Pending legal-status Critical Current

Links

JP2022549759A 2020-02-19 2021-02-19 免疫チェックポイント阻害剤による治療に対して腫瘍を感作させる多重膜rnaナノ粒子および方法 Pending JP2023515927A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202062978694P 2020-02-19 2020-02-19
US62/978,694 2020-02-19
PCT/US2021/018831 WO2021168290A1 (en) 2020-02-19 2021-02-19 Multilamellar rna nanoparticles and methods of sensitizing tumors to treatment with immune checkpoint inhibitors

Publications (2)

Publication Number Publication Date
JP2023515927A JP2023515927A (ja) 2023-04-17
JP2023515927A5 true JP2023515927A5 (https=) 2024-02-27

Family

ID=77392250

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2022549759A Pending JP2023515927A (ja) 2020-02-19 2021-02-19 免疫チェックポイント阻害剤による治療に対して腫瘍を感作させる多重膜rnaナノ粒子および方法

Country Status (6)

Country Link
US (1) US20230346700A1 (https=)
EP (1) EP4106730A4 (https=)
JP (1) JP2023515927A (https=)
AU (1) AU2021222036A1 (https=)
CA (1) CA3168509A1 (https=)
WO (1) WO2021168290A1 (https=)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP7783628B2 (ja) * 2019-07-19 2025-12-10 ユニバーシティ オブ フロリダ リサーチ ファンデーション インコーポレーティッド 多層rnaナノ粒子
WO2023196232A1 (en) * 2022-04-04 2023-10-12 University Of Florida Research Foundation, Inc. Method of characterizing tumors
WO2025207807A1 (en) * 2024-03-27 2025-10-02 The University Of Florida Research Foundation, Inc. Ctc rna-loaded nanoparticles and use thereof for the treatment of cancer
WO2025207936A1 (en) * 2024-03-28 2025-10-02 Mirror Biologics, Inc. Treatment for colorectal cancer using immune checkpoint inhibitors

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2016341309A1 (en) * 2015-10-22 2018-06-07 Modernatx, Inc. Cancer vaccines
SI3458083T1 (sl) * 2016-05-18 2023-03-31 Modernatx, Inc. Polinukleotidi, ki kodirajo interlevkin-12 (IL12) in njihova uporaba
JP2020514370A (ja) * 2017-03-17 2020-05-21 キュアバック アーゲー 組合せ抗癌療法のためのrnaワクチン及び免疫チェックポイント阻害剤
CN112367974A (zh) * 2018-05-15 2021-02-12 DNALite治疗学公司 粘液穿透肽、递送媒介和治疗方法
WO2020037102A1 (en) * 2018-08-15 2020-02-20 University Of Florida Research Foundation, Inc. Methods of sensitizing tumors to treatment with immune checkpoint inhibitors
JP7783628B2 (ja) * 2019-07-19 2025-12-10 ユニバーシティ オブ フロリダ リサーチ ファンデーション インコーポレーティッド 多層rnaナノ粒子

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