JP2023515927A5 - - Google Patents
Info
- Publication number
- JP2023515927A5 JP2023515927A5 JP2022549759A JP2022549759A JP2023515927A5 JP 2023515927 A5 JP2023515927 A5 JP 2023515927A5 JP 2022549759 A JP2022549759 A JP 2022549759A JP 2022549759 A JP2022549759 A JP 2022549759A JP 2023515927 A5 JP2023515927 A5 JP 2023515927A5
- Authority
- JP
- Japan
- Prior art keywords
- composition according
- nanoparticles
- nucleic acid
- cationic lipid
- tumor
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202062978694P | 2020-02-19 | 2020-02-19 | |
| US62/978,694 | 2020-02-19 | ||
| PCT/US2021/018831 WO2021168290A1 (en) | 2020-02-19 | 2021-02-19 | Multilamellar rna nanoparticles and methods of sensitizing tumors to treatment with immune checkpoint inhibitors |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2023515927A JP2023515927A (ja) | 2023-04-17 |
| JP2023515927A5 true JP2023515927A5 (https=) | 2024-02-27 |
Family
ID=77392250
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022549759A Pending JP2023515927A (ja) | 2020-02-19 | 2021-02-19 | 免疫チェックポイント阻害剤による治療に対して腫瘍を感作させる多重膜rnaナノ粒子および方法 |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US20230346700A1 (https=) |
| EP (1) | EP4106730A4 (https=) |
| JP (1) | JP2023515927A (https=) |
| AU (1) | AU2021222036A1 (https=) |
| CA (1) | CA3168509A1 (https=) |
| WO (1) | WO2021168290A1 (https=) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP7783628B2 (ja) * | 2019-07-19 | 2025-12-10 | ユニバーシティ オブ フロリダ リサーチ ファンデーション インコーポレーティッド | 多層rnaナノ粒子 |
| WO2023196232A1 (en) * | 2022-04-04 | 2023-10-12 | University Of Florida Research Foundation, Inc. | Method of characterizing tumors |
| WO2025207807A1 (en) * | 2024-03-27 | 2025-10-02 | The University Of Florida Research Foundation, Inc. | Ctc rna-loaded nanoparticles and use thereof for the treatment of cancer |
| WO2025207936A1 (en) * | 2024-03-28 | 2025-10-02 | Mirror Biologics, Inc. | Treatment for colorectal cancer using immune checkpoint inhibitors |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2016341309A1 (en) * | 2015-10-22 | 2018-06-07 | Modernatx, Inc. | Cancer vaccines |
| SI3458083T1 (sl) * | 2016-05-18 | 2023-03-31 | Modernatx, Inc. | Polinukleotidi, ki kodirajo interlevkin-12 (IL12) in njihova uporaba |
| JP2020514370A (ja) * | 2017-03-17 | 2020-05-21 | キュアバック アーゲー | 組合せ抗癌療法のためのrnaワクチン及び免疫チェックポイント阻害剤 |
| CN112367974A (zh) * | 2018-05-15 | 2021-02-12 | DNALite治疗学公司 | 粘液穿透肽、递送媒介和治疗方法 |
| WO2020037102A1 (en) * | 2018-08-15 | 2020-02-20 | University Of Florida Research Foundation, Inc. | Methods of sensitizing tumors to treatment with immune checkpoint inhibitors |
| JP7783628B2 (ja) * | 2019-07-19 | 2025-12-10 | ユニバーシティ オブ フロリダ リサーチ ファンデーション インコーポレーティッド | 多層rnaナノ粒子 |
-
2021
- 2021-02-19 EP EP21756388.1A patent/EP4106730A4/en active Pending
- 2021-02-19 CA CA3168509A patent/CA3168509A1/en active Pending
- 2021-02-19 WO PCT/US2021/018831 patent/WO2021168290A1/en not_active Ceased
- 2021-02-19 AU AU2021222036A patent/AU2021222036A1/en active Pending
- 2021-02-19 JP JP2022549759A patent/JP2023515927A/ja active Pending
- 2021-02-19 US US17/800,687 patent/US20230346700A1/en active Pending
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2023515927A5 (https=) | ||
| Lu et al. | Nucleic acid drug vectors for diagnosis and treatment of brain diseases | |
| Li et al. | The roles of exosomes in cancer drug resistance and its therapeutic application | |
| JP6023126B2 (ja) | 標的遺伝子の発現を抑制する組成物 | |
| Tagami et al. | Anti-PEG IgM production by siRNA encapsulated in a PEGylated lipid nanocarrier is dependent on the sequence of the siRNA | |
| Tyagi et al. | Exploiting nanotechnology for the development of microRNA-based cancer therapeutics | |
| Li et al. | Effect of immune response on gene transfer to the lung via systemic administration of cationic lipidic vectors | |
| Wang et al. | Targeted delivery of tumor suppressor microRNA-1 by transferrin-conjugated lipopolyplex nanoparticles to patient-derived glioblastoma stem cells | |
| JP2022528487A (ja) | C9orf72のオリゴヌクレオチドベースの調節 | |
| WO2016145008A2 (en) | Mirna for treatment of breast cancer | |
| Wang et al. | Tumor-derived extracellular vesicles regulate macrophage polarization: role and therapeutic perspectives | |
| CN102112136A (zh) | 抑制靶基因表达的组合物 | |
| JP2023512707A5 (https=) | ||
| JP2021523145A5 (https=) | ||
| CN115141844A (zh) | 一种rna质粒递送系统及其应用 | |
| Fu et al. | Research progress in exosome-based nanoscale drug carriers in tumor therapies | |
| JP2025138644A5 (https=) | ||
| WO2019043709A9 (en) | COMPOSITIONS AND METHODS FOR TREATING FIBROTIC DISEASES | |
| WO2017067188A1 (zh) | 一种药物组合物及其应用 | |
| Soleimani et al. | CD73 downregulation by EGFR-targeted liposomal CD73 siRNA potentiates antitumor effect of liposomal doxorubicin in 4T1 tumor-bearing mice | |
| WO2021016106A8 (en) | Multilamellar rna nanoparticles | |
| Zhang et al. | Nanotherapeutic Approaches of Interleukin‐3 to Clear the α‐Synuclein Pathology in Mouse Models of Parkinson's Disease | |
| Tabasi et al. | Transitional insight into the RNA-based oligonucleotides in cancer treatment | |
| CN119405823B (zh) | 一种基于g四链体rna的蛋白降解靶向嵌合体及其制备方法与应用 | |
| Alemi et al. | Applications of engineered exosomes in drugging noncoding RNAs for cancer therapy |