JP2025138644A5 - - Google Patents
Info
- Publication number
- JP2025138644A5 JP2025138644A5 JP2025089202A JP2025089202A JP2025138644A5 JP 2025138644 A5 JP2025138644 A5 JP 2025138644A5 JP 2025089202 A JP2025089202 A JP 2025089202A JP 2025089202 A JP2025089202 A JP 2025089202A JP 2025138644 A5 JP2025138644 A5 JP 2025138644A5
- Authority
- JP
- Japan
- Prior art keywords
- nanoparticle
- cationic lipid
- nucleic acid
- pharmaceutical composition
- layers
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (10)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201962876440P | 2019-07-19 | 2019-07-19 | |
| US62/876,440 | 2019-07-19 | ||
| US201962877598P | 2019-07-23 | 2019-07-23 | |
| US62/877,598 | 2019-07-23 | ||
| US201962884983P | 2019-08-09 | 2019-08-09 | |
| US62/884,983 | 2019-08-09 | ||
| US201962933326P | 2019-11-08 | 2019-11-08 | |
| US62/933,326 | 2019-11-08 | ||
| JP2022503898A JP7783628B2 (ja) | 2019-07-19 | 2020-07-17 | 多層ｒｎａナノ粒子 |
| PCT/US2020/042606 WO2021016106A1 (en) | 2019-07-19 | 2020-07-17 | Multilamellar rna nanoparticles |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022503898A Division JP7783628B2 (ja) | 2019-07-19 | 2020-07-17 | 多層ｒｎａナノ粒子 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2025138644A JP2025138644A (ja) | 2025-09-25 |
| JP2025138644A5 true JP2025138644A5 (https=) | 2026-02-20 |
Family
ID=74193752
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022503898A Active JP7783628B2 (ja) | 2019-07-19 | 2020-07-17 | 多層ｒｎａナノ粒子 |
| JP2025089202A Pending JP2025138644A (ja) | 2019-07-19 | 2025-05-28 | 多層ｒｎａナノ粒子 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022503898A Active JP7783628B2 (ja) | 2019-07-19 | 2020-07-17 | 多層ｒｎａナノ粒子 |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US20220287969A1 (https=) |
| EP (1) | EP3999034A4 (https=) |
| JP (2) | JP7783628B2 (https=) |
| KR (1) | KR20220035434A (https=) |
| AU (1) | AU2020316335B2 (https=) |
| BR (1) | BR112022000925A2 (https=) |
| CA (1) | CA3144388A1 (https=) |
| WO (1) | WO2021016106A1 (https=) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP4106730A4 (en) * | 2020-02-19 | 2024-03-27 | University of Florida Research Foundation, Incorporated | MULTILAMELLAR RNA NANOPARTICLES AND METHODS FOR SENSITIZING TUMORS TO TREATMENT WITH IMMUNE CHECKPOINT INHIBITORS |
| EP4126030A1 (en) * | 2020-04-01 | 2023-02-08 | University Of Florida Research Foundation, Incorporated | Multilamellar rna nanoparticle vaccine against sars-cov-2 |
| US20240238418A1 (en) * | 2021-05-07 | 2024-07-18 | University Of Florida Research Foundation, Inc. | Car t cell therapy method |
| WO2024263713A1 (en) * | 2023-06-21 | 2024-12-26 | University Of Florida Research Foundation, Incorporated | Materials and methods of using proinsulin mrna nanoparticles |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20130323165A1 (en) * | 2010-03-08 | 2013-12-05 | Northeastern University | Magnetic Nanoplatforms for Theranostic and Multi-Modal Imaging Applications |
| RU2013154295A (ru) * | 2011-06-08 | 2015-07-20 | Шир Хьюман Дженетик Терапис, Инк. | КОМПОЗИЦИИ ЛИПИДНЫХ НАНОЧАСТИЦ И СПОСОБЫ ДЛЯ ДОСТАВКИ мРНК |
| EP2858679B2 (en) * | 2012-06-08 | 2024-06-05 | Translate Bio, Inc. | Pulmonary delivery of mrna to non-lung target cells |
| ITRM20120480A1 (it) * | 2012-10-09 | 2014-04-10 | Uni Degli Studi Camerino | Nanoparticelle lipidiche multicomponenti e procedimenti per la loro preparazione. |
| US9950065B2 (en) * | 2013-09-26 | 2018-04-24 | Biontech Rna Pharmaceuticals Gmbh | Particles comprising a shell with RNA |
| EP3160448B1 (en) * | 2014-06-26 | 2025-08-06 | Ramot at Tel-Aviv University Ltd. | Liposomal formulations for delivery of nucleic acids |
| WO2017062502A1 (en) * | 2015-10-05 | 2017-04-13 | The Regents Of The University Of Colorgo, A Body Corporate | Lipoplexes formulated for catalytic delivery |
| EP3790533A1 (en) * | 2018-05-08 | 2021-03-17 | University of Florida Research Foundation, Incorporated | Magnetic liposomes and related treatment and imaging methods |
| WO2020037102A1 (en) * | 2018-08-15 | 2020-02-20 | University Of Florida Research Foundation, Inc. | Methods of sensitizing tumors to treatment with immune checkpoint inhibitors |
| US20220054610A1 (en) * | 2018-09-12 | 2022-02-24 | University Of Florida Research Foundation, Inc. | Slow-cycling cell-rna based nanoparticle vaccine to treat cancer |
| US20230096704A1 (en) * | 2020-02-05 | 2023-03-30 | University Of Florida Research Foundation, Incorporated | Rna-loaded nanoparticles and use thereof for the treatment of cancer |
| EP4106730A4 (en) * | 2020-02-19 | 2024-03-27 | University of Florida Research Foundation, Incorporated | MULTILAMELLAR RNA NANOPARTICLES AND METHODS FOR SENSITIZING TUMORS TO TREATMENT WITH IMMUNE CHECKPOINT INHIBITORS |
| EP4126030A1 (en) * | 2020-04-01 | 2023-02-08 | University Of Florida Research Foundation, Incorporated | Multilamellar rna nanoparticle vaccine against sars-cov-2 |
| US20240299516A1 (en) * | 2020-12-21 | 2024-09-12 | University Of Florida Research Foundaton, Inc. | Multilamellar rna nanoparticle vaccine against cancer |
| US20240238418A1 (en) * | 2021-05-07 | 2024-07-18 | University Of Florida Research Foundation, Inc. | Car t cell therapy method |
| WO2023196232A1 (en) * | 2022-04-04 | 2023-10-12 | University Of Florida Research Foundation, Inc. | Method of characterizing tumors |
-
2020
- 2020-07-17 JP JP2022503898A patent/JP7783628B2/ja active Active
- 2020-07-17 BR BR112022000925A patent/BR112022000925A2/pt unknown
- 2020-07-17 KR KR1020227004840A patent/KR20220035434A/ko active Pending
- 2020-07-17 EP EP20845106.2A patent/EP3999034A4/en active Pending
- 2020-07-17 US US17/626,674 patent/US20220287969A1/en active Pending
- 2020-07-17 CA CA3144388A patent/CA3144388A1/en active Pending
- 2020-07-17 AU AU2020316335A patent/AU2020316335B2/en active Active
- 2020-07-17 WO PCT/US2020/042606 patent/WO2021016106A1/en not_active Ceased
-
2025
- 2025-05-28 JP JP2025089202A patent/JP2025138644A/ja active Pending
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2025138644A5 (https=) | ||
| Belhadj et al. | Current advances in non‐viral gene delivery systems: Liposomes versus extracellular vesicles | |
| JP2023520506A5 (https=) | ||
| CN109152735B (zh) | 包含亲脂性抗炎剂的脂质纳米颗粒及其使用方法 | |
| JP2023512707A5 (https=) | ||
| Shi et al. | Differentially charged hollow core/shell lipid-polymer-lipid hybrid nanoparticle for small interfering RNA delivery | |
| EP2549986B1 (en) | Multi-compartmental macrophage delivery | |
| EP2459724B1 (en) | Cell-targeting nanoparticles comprising polynucleotide agents and uses thereof | |
| Ai et al. | Cartilage‐targeting ultrasmall lipid‐polymer hybrid nanoparticles for the prevention of cartilage degradation | |
| JP2019519568A5 (https=) | ||
| CN112076158B (zh) | 一种治疗慢性肾炎的脂质体-纳米粒复合体 | |
| JP2023515927A5 (https=) | ||
| CN115141829A (zh) | 一种基因线路、rna递送系统及其应用 | |
| Ding et al. | Hybrid organic nanotubes with dual functionalities localized on cylindrical nanochannels control the release of doxorubicin | |
| JP2021523145A5 (https=) | ||
| CN113384530B (zh) | 一种多糖核心Nanocells及其制备方法与应用 | |
| CN102274186B (zh) | 一种用于抗癌的镜像多肽脂质纳米制剂 | |
| Shanker et al. | Tumor suppressor gene‐based nanotherapy: from test tube to the clinic | |
| Marcato | Pharmacokinetics and pharmacodynamics of nanomaterials | |
| CN119405823B (zh) | 一种基于g四链体rna的蛋白降解靶向嵌合体及其制备方法与应用 | |
| CN103181897A (zh) | 吉非替尼脂质体制剂及其制备方法 | |
| Xu et al. | Conversion of chemical drugs into targeting ligands on RNA nanoparticles and assessing payload stoichiometry for optimal biodistribution in cancer treatment | |
| Grandhi et al. | Design, synthesis, and functionalization of nanomaterials for therapeutic drug delivery | |
| CN110279661A (zh) | 一种纳米颗粒组合物递送系统、制备方法及其用途 | |
| CN113660938A (zh) | 核酸递送复合物 |