JP2025138644A5 - - Google Patents

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Publication number
JP2025138644A5
JP2025138644A5 JP2025089202A JP2025089202A JP2025138644A5 JP 2025138644 A5 JP2025138644 A5 JP 2025138644A5 JP 2025089202 A JP2025089202 A JP 2025089202A JP 2025089202 A JP2025089202 A JP 2025089202A JP 2025138644 A5 JP2025138644 A5 JP 2025138644A5
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JP
Japan
Prior art keywords
nanoparticle
cationic lipid
nucleic acid
pharmaceutical composition
layers
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2025089202A
Other languages
English (en)
Japanese (ja)
Other versions
JP2025138644A (ja
Filing date
Publication date
Priority claimed from JP2022503898A external-priority patent/JP7783628B2/ja
Application filed filed Critical
Publication of JP2025138644A publication Critical patent/JP2025138644A/ja
Publication of JP2025138644A5 publication Critical patent/JP2025138644A5/ja
Pending legal-status Critical Current

Links

JP2025089202A 2019-07-19 2025-05-28 多層ｒｎａナノ粒子 Pending JP2025138644A (ja)

Applications Claiming Priority (10)

Application Number Priority Date Filing Date Title
US201962876440P 2019-07-19 2019-07-19
US62/876,440 2019-07-19
US201962877598P 2019-07-23 2019-07-23
US62/877,598 2019-07-23
US201962884983P 2019-08-09 2019-08-09
US62/884,983 2019-08-09
US201962933326P 2019-11-08 2019-11-08
US62/933,326 2019-11-08
JP2022503898A JP7783628B2 (ja) 2019-07-19 2020-07-17 多層ｒｎａナノ粒子
PCT/US2020/042606 WO2021016106A1 (en) 2019-07-19 2020-07-17 Multilamellar rna nanoparticles

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
JP2022503898A Division JP7783628B2 (ja) 2019-07-19 2020-07-17 多層ｒｎａナノ粒子

Publications (2)

Publication Number Publication Date
JP2025138644A JP2025138644A (ja) 2025-09-25
JP2025138644A5 true JP2025138644A5 (https=) 2026-02-20

Family

ID=74193752

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2022503898A Active JP7783628B2 (ja) 2019-07-19 2020-07-17 多層ｒｎａナノ粒子
JP2025089202A Pending JP2025138644A (ja) 2019-07-19 2025-05-28 多層ｒｎａナノ粒子

Family Applications Before (1)

Application Number Title Priority Date Filing Date
JP2022503898A Active JP7783628B2 (ja) 2019-07-19 2020-07-17 多層ｒｎａナノ粒子

Country Status (8)

Country Link
US (1) US20220287969A1 (https=)
EP (1) EP3999034A4 (https=)
JP (2) JP7783628B2 (https=)
KR (1) KR20220035434A (https=)
AU (1) AU2020316335B2 (https=)
BR (1) BR112022000925A2 (https=)
CA (1) CA3144388A1 (https=)
WO (1) WO2021016106A1 (https=)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20230346700A1 (en) * 2020-02-19 2023-11-02 University Of Florida Research Foundation, Incorporated Multilamellar RNA Nanoparticles and Methods of Sensitizing Tumors to Treatment with Immune Checkpoint Inhibitors
CA3174187A1 (en) * 2020-04-01 2021-10-07 University Of Florida Research Foundation, Incorporated Multilamellar rna nanoparticle vaccine against sars-cov-2
JP2024517287A (ja) * 2021-05-07 2024-04-19 ユニバーシティ オブ フロリダ リサーチ ファンデーション インコーポレーティッド Ｃａｒ ｔ細胞療法の方法
WO2024263713A1 (en) * 2023-06-21 2024-12-26 University Of Florida Research Foundation, Incorporated Materials and methods of using proinsulin mrna nanoparticles

Family Cites Families (16)

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Publication number Priority date Publication date Assignee Title
WO2011112597A1 (en) * 2010-03-08 2011-09-15 Northeastern University Magnetic nanoplatforms for theranostic and multi-modal imaging applications
PL3586861T3 (pl) * 2011-06-08 2022-05-23 Translate Bio, Inc. Kompozycje nanocząstek lipidowych i sposoby dostarczania mrna
US10245229B2 (en) * 2012-06-08 2019-04-02 Translate Bio, Inc. Pulmonary delivery of mRNA to non-lung target cells
ITRM20120480A1 (it) * 2012-10-09 2014-04-10 Uni Degli Studi Camerino Nanoparticelle lipidiche multicomponenti e procedimenti per la loro preparazione.
CA2925047C (en) 2013-09-26 2021-03-23 Biontech Ag Rna decorated particles
US10583084B2 (en) 2014-06-26 2020-03-10 Ramot At Tel-Aviv University Ltd. Liposomal formulations for delivery of nucleic acids
WO2017062502A1 (en) * 2015-10-05 2017-04-13 The Regents Of The University Of Colorgo, A Body Corporate Lipoplexes formulated for catalytic delivery
CA3099519A1 (en) * 2018-05-08 2019-11-14 University Of Florida Research Foundation, Incorporated Magnetic liposomes and related treatment and imaging methods
WO2020037102A1 (en) * 2018-08-15 2020-02-20 University Of Florida Research Foundation, Inc. Methods of sensitizing tumors to treatment with immune checkpoint inhibitors
EP3849597A1 (en) * 2018-09-12 2021-07-21 University of Florida Research Foundation, Inc. Slow-cycling cell-rna based nanoparticle vaccine to treat cancer
EP4099988A4 (en) * 2020-02-05 2024-03-13 University of Florida Research Foundation, Incorporated Rna-loaded nanoparticles and use thereof for the treatment of cancer
US20230346700A1 (en) * 2020-02-19 2023-11-02 University Of Florida Research Foundation, Incorporated Multilamellar RNA Nanoparticles and Methods of Sensitizing Tumors to Treatment with Immune Checkpoint Inhibitors
CA3174187A1 (en) * 2020-04-01 2021-10-07 University Of Florida Research Foundation, Incorporated Multilamellar rna nanoparticle vaccine against sars-cov-2
WO2022140278A1 (en) * 2020-12-21 2022-06-30 University Of Florida Research Foundation, Inc. Multilamellar rna nanoparticle vaccine against cancer
JP2024517287A (ja) * 2021-05-07 2024-04-19 ユニバーシティ オブ フロリダ リサーチ ファンデーション インコーポレーティッド Ｃａｒ ｔ細胞療法の方法
WO2023196232A1 (en) * 2022-04-04 2023-10-12 University Of Florida Research Foundation, Inc. Method of characterizing tumors

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