JP2023515927A - 免疫チェックポイント阻害剤による治療に対して腫瘍を感作させる多重膜rnaナノ粒子および方法 - Google Patents

免疫チェックポイント阻害剤による治療に対して腫瘍を感作させる多重膜rnaナノ粒子および方法 Download PDF

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JP2023515927A
JP2023515927A JP2022549759A JP2022549759A JP2023515927A JP 2023515927 A JP2023515927 A JP 2023515927A JP 2022549759 A JP2022549759 A JP 2022549759A JP 2022549759 A JP2022549759 A JP 2022549759A JP 2023515927 A JP2023515927 A JP 2023515927A
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セイヤー、エリアス
ルーベン メンデス-ゴメス、ヘクター
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ユニバーシティ オブ フロリダ リサーチ ファンデーション インコーポレーティッド
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JP2022549759A 2020-02-19 2021-02-19 免疫チェックポイント阻害剤による治療に対して腫瘍を感作させる多重膜rnaナノ粒子および方法 Pending JP2023515927A (ja)

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US202062978694P 2020-02-19 2020-02-19
US62/978,694 2020-02-19
PCT/US2021/018831 WO2021168290A1 (en) 2020-02-19 2021-02-19 Multilamellar rna nanoparticles and methods of sensitizing tumors to treatment with immune checkpoint inhibitors

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JP2023515927A true JP2023515927A (ja) 2023-04-17
JPWO2021168290A5 JPWO2021168290A5 (https=) 2024-02-27
JP2023515927A5 JP2023515927A5 (https=) 2024-02-27

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US (1) US20230346700A1 (https=)
EP (1) EP4106730A4 (https=)
JP (1) JP2023515927A (https=)
AU (1) AU2021222036A1 (https=)
CA (1) CA3168509A1 (https=)
WO (1) WO2021168290A1 (https=)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3999034A4 (en) * 2019-07-19 2023-08-23 University Of Florida Research Foundation, Incorporated Multilamellar rna nanoparticles
WO2023196232A1 (en) * 2022-04-04 2023-10-12 University Of Florida Research Foundation, Inc. Method of characterizing tumors
WO2025207807A1 (en) * 2024-03-27 2025-10-02 The University Of Florida Research Foundation, Inc. Ctc rna-loaded nanoparticles and use thereof for the treatment of cancer
WO2025207936A1 (en) * 2024-03-28 2025-10-02 Mirror Biologics, Inc. Treatment for colorectal cancer using immune checkpoint inhibitors

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2018167320A1 (en) * 2017-03-17 2018-09-20 Curevac Ag Rna vaccine and immune checkpoint inhibitors for combined anticancer therapy
WO2019222400A2 (en) * 2018-05-15 2019-11-21 Dnalite Therapeutics, Inc. Mucus-penetrating peptides, delivery vehicles and methods of therapy

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3364949A4 (en) * 2015-10-22 2019-07-31 ModernaTX, Inc. CANCER VACCINES
KR102469450B1 (ko) * 2016-05-18 2022-11-22 모더나티엑스, 인크. 인터류킨-12 (il12)를 코딩하는 폴리뉴클레오티드 및 그의 용도
WO2020037102A1 (en) * 2018-08-15 2020-02-20 University Of Florida Research Foundation, Inc. Methods of sensitizing tumors to treatment with immune checkpoint inhibitors
EP3999034A4 (en) * 2019-07-19 2023-08-23 University Of Florida Research Foundation, Incorporated Multilamellar rna nanoparticles

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2018167320A1 (en) * 2017-03-17 2018-09-20 Curevac Ag Rna vaccine and immune checkpoint inhibitors for combined anticancer therapy
WO2019222400A2 (en) * 2018-05-15 2019-11-21 Dnalite Therapeutics, Inc. Mucus-penetrating peptides, delivery vehicles and methods of therapy

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AU2021222036A1 (en) 2022-09-22
EP4106730A4 (en) 2024-03-27
CA3168509A1 (en) 2021-08-26
US20230346700A1 (en) 2023-11-02
WO2021168290A1 (en) 2021-08-26
EP4106730A1 (en) 2022-12-28

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