JP2023515223A5 - - Google Patents

Info

Publication number
JP2023515223A5
JP2023515223A5 JP2022551774A JP2022551774A JP2023515223A5 JP 2023515223 A5 JP2023515223 A5 JP 2023515223A5 JP 2022551774 A JP2022551774 A JP 2022551774A JP 2022551774 A JP2022551774 A JP 2022551774A JP 2023515223 A5 JP2023515223 A5 JP 2023515223A5
Authority
JP
Japan
Prior art keywords
amino acid
acid sequences
identity
seq
nos
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2022551774A
Other languages
English (en)
Japanese (ja)
Other versions
JP7711079B2 (ja
JP2023515223A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/CN2021/077784 external-priority patent/WO2021170020A1/en
Publication of JP2023515223A publication Critical patent/JP2023515223A/ja
Publication of JP2023515223A5 publication Critical patent/JP2023515223A5/ja
Priority to JP2025114877A priority Critical patent/JP2025157317A/ja
Application granted granted Critical
Publication of JP7711079B2 publication Critical patent/JP7711079B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

JP2022551774A 2020-02-27 2021-02-25 Il4rに結合する抗体とその使用 Active JP7711079B2 (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2025114877A JP2025157317A (ja) 2020-02-27 2025-07-08 Il4rに結合する抗体とその使用

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202062982521P 2020-02-27 2020-02-27
US62/982,521 2020-02-27
PCT/CN2021/077784 WO2021170020A1 (en) 2020-02-27 2021-02-25 Antibodies binding il4r and uses thereof

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2025114877A Division JP2025157317A (ja) 2020-02-27 2025-07-08 Il4rに結合する抗体とその使用

Publications (3)

Publication Number Publication Date
JP2023515223A JP2023515223A (ja) 2023-04-12
JP2023515223A5 true JP2023515223A5 (https=) 2024-03-05
JP7711079B2 JP7711079B2 (ja) 2025-07-22

Family

ID=75108091

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2022551774A Active JP7711079B2 (ja) 2020-02-27 2021-02-25 Il4rに結合する抗体とその使用
JP2025114877A Pending JP2025157317A (ja) 2020-02-27 2025-07-08 Il4rに結合する抗体とその使用

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2025114877A Pending JP2025157317A (ja) 2020-02-27 2025-07-08 Il4rに結合する抗体とその使用

Country Status (12)

Country Link
US (1) US20230105029A1 (https=)
EP (1) EP4110816A1 (https=)
JP (2) JP7711079B2 (https=)
KR (1) KR20220147642A (https=)
CN (4) CN119708231A (https=)
AU (1) AU2021228061A1 (https=)
BR (1) BR112022017174A2 (https=)
CA (1) CA3169479A1 (https=)
MX (1) MX2022010665A (https=)
TW (1) TWI859419B (https=)
WO (1) WO2021170020A1 (https=)
ZA (1) ZA202210628B (https=)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW202313692A (zh) * 2021-08-26 2023-04-01 大陸商正大天晴藥業集團股份有限公司 抗il4r抗體的藥物組成物及其用途
WO2023235738A1 (en) * 2022-06-02 2023-12-07 Eli Lilly And Company Human interleukin-4 receptor alpha antibody glucocorticoid conjugates
KR20240038841A (ko) * 2022-09-16 2024-03-26 연세대학교 산학협력단 신규한 인간 인터류킨-4 수용체 결합 나노바디 및 이의 용도
US20260109758A1 (en) * 2022-09-22 2026-04-23 Biosion, Inc. Recombinant bispecific antibodies targeting tslp and il4r
CN121693518A (zh) * 2023-08-01 2026-03-17 先声药业有限公司 抗il4r抗体及其应用
CN117924490B (zh) * 2023-12-22 2024-10-22 华润生物医药有限公司 抗il-4r抗体及其用途
CN117924491B (zh) * 2023-12-22 2024-10-18 华润生物医药有限公司 抗il-4r抗体及其用途
US20250388685A1 (en) 2024-04-15 2025-12-25 Sanofi Biotechnology Methods for treating chronic rhinosinusitis without nasal polyps by administering an il-4r antagonist
WO2026055687A1 (en) 2024-09-09 2026-03-12 Regeneron Pharmaceuticals, Inc. Methods for treating bullous pemphigoid by administering an il-4r antagonist
WO2026059949A1 (en) 2024-09-10 2026-03-19 Sanofi Biotechnology Methods for treating chronic pruritus of unknown origin (cpuo) by administering an il-4r antagonist

Family Cites Families (58)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4475196A (en) 1981-03-06 1984-10-02 Zor Clair G Instrument for locating faults in aircraft passenger reading light and attendant call control system
US4447233A (en) 1981-04-10 1984-05-08 Parker-Hannifin Corporation Medication infusion pump
US4439196A (en) 1982-03-18 1984-03-27 Merck & Co., Inc. Osmotic drug delivery system
US4522811A (en) 1982-07-08 1985-06-11 Syntex (U.S.A.) Inc. Serial injection of muramyldipeptides and liposomes enhances the anti-infective activity of muramyldipeptides
US4447224A (en) 1982-09-20 1984-05-08 Infusaid Corporation Variable flow implantable infusion apparatus
US4487603A (en) 1982-11-26 1984-12-11 Cordis Corporation Implantable microinfusion pump system
US4816567A (en) 1983-04-08 1989-03-28 Genentech, Inc. Recombinant immunoglobin preparations
US4486194A (en) 1983-06-08 1984-12-04 James Ferrara Therapeutic device for administering medicaments through the skin
DE3572982D1 (en) 1984-03-06 1989-10-19 Takeda Chemical Industries Ltd Chemically modified lymphokine and production thereof
US4596556A (en) 1985-03-25 1986-06-24 Bioject, Inc. Hypodermic injection apparatus
US5374548A (en) 1986-05-02 1994-12-20 Genentech, Inc. Methods and compositions for the attachment of proteins to liposomes using a glycophospholipid anchor
MX9203291A (es) 1985-06-26 1992-08-01 Liposome Co Inc Metodo para acoplamiento de liposomas.
GB8601597D0 (en) 1986-01-23 1986-02-26 Wilson R H Nucleotide sequences
US5225539A (en) 1986-03-27 1993-07-06 Medical Research Council Recombinant altered antibodies and methods of making altered antibodies
US4941880A (en) 1987-06-19 1990-07-17 Bioject, Inc. Pre-filled ampule and non-invasive hypodermic injection device assembly
US4790824A (en) 1987-06-19 1988-12-13 Bioject, Inc. Non-invasive hypodermic injection device
GB8717430D0 (en) 1987-07-23 1987-08-26 Celltech Ltd Recombinant dna product
US5677425A (en) 1987-09-04 1997-10-14 Celltech Therapeutics Limited Recombinant antibody
GB8809129D0 (en) 1988-04-18 1988-05-18 Celltech Ltd Recombinant dna methods vectors and host cells
WO1990006952A1 (fr) 1988-12-22 1990-06-28 Kirin-Amgen, Inc. Facteur de stimulation de colonies de granulocytes modifies chimiquement
US5530101A (en) 1988-12-28 1996-06-25 Protein Design Labs, Inc. Humanized immunoglobulins
US5108921A (en) 1989-04-03 1992-04-28 Purdue Research Foundation Method for enhanced transmembrane transport of exogenous molecules
US5064413A (en) 1989-11-09 1991-11-12 Bioject, Inc. Needleless hypodermic injection device
US5312335A (en) 1989-11-09 1994-05-17 Bioject Inc. Needleless hypodermic injection device
GB9108652D0 (en) 1991-04-23 1991-06-12 Antisoma Ltd Immunoreactive compounds
US5714350A (en) 1992-03-09 1998-02-03 Protein Design Labs, Inc. Increasing antibody affinity by altering glycosylation in the immunoglobulin variable region
CA2118508A1 (en) 1992-04-24 1993-11-11 Elizabeth S. Ward Recombinant production of immunoglobulin-like domains in prokaryotic cells
US5383851A (en) 1992-07-24 1995-01-24 Bioject Inc. Needleless hypodermic injection device
DE69332643T2 (de) 1992-09-16 2003-11-27 The Scripps Research Institute, La Jolla Menschliche, neutralisierende, monoklonale antikörper gegen das respiratorische synzytialvirus
JP3919830B2 (ja) 1992-11-28 2007-05-30 財団法人化学及血清療法研究所 抗ネコヘルペスウイルス−1組換え抗体および該抗体をコードする遺伝子断片
WO1995018634A1 (en) 1994-01-04 1995-07-13 The Scripps Research Institute Human monoclonal antibodies to herpes simplex virus and methods therefor
US6090382A (en) 1996-02-09 2000-07-18 Basf Aktiengesellschaft Human antibodies that bind human TNFα
EP0983303B1 (en) 1997-05-21 2006-03-08 Biovation Limited Method for the production of non-immunogenic proteins
GB9814383D0 (en) 1998-07-02 1998-09-02 Cambridge Antibody Tech Improvements relating to antibodies
JP4593783B2 (ja) 1998-07-21 2010-12-08 ゲンマブ・アクティーゼルスカブ 抗c型肝炎ウイルス抗体およびその使用
US6914128B1 (en) 1999-03-25 2005-07-05 Abbott Gmbh & Co. Kg Human antibodies that bind human IL-12 and methods for producing
CA2704600C (en) 1999-04-09 2016-10-25 Kyowa Kirin Co., Ltd. A method for producing antibodies with increased adcc activity
US6818216B2 (en) 2000-11-28 2004-11-16 Medimmune, Inc. Anti-RSV antibodies
US6989452B2 (en) 2001-05-31 2006-01-24 Medarex, Inc. Disulfide prodrugs and linkers and stabilizers useful therefor
CA2463879C (en) 2001-10-25 2012-12-04 Genentech, Inc. Glycoprotein compositions
BR0309145A (pt) 2002-04-09 2005-02-01 Kyowa Hakko Kogyo Kk Células das quais o genoma é modificado
BRPI0416603A (pt) * 2003-11-07 2007-01-30 Immunex Corp anticorpo que se liga ao receptor interleucina-4 (il-4) humano
US7691962B2 (en) 2004-05-19 2010-04-06 Medarex, Inc. Chemical linkers and conjugates thereof
JP4806680B2 (ja) 2004-05-19 2011-11-02 メダレックス インコーポレイテッド 自己犠牲リンカー及び薬剤複合体
CN101160324B (zh) 2005-02-18 2013-04-24 米德列斯公司 缺乏岩藻糖残基的抗前列腺特异性膜抗原(psma)单克隆抗体
US7714016B2 (en) 2005-04-08 2010-05-11 Medarex, Inc. Cytotoxic compounds and conjugates with cleavable substrates
EP2354163A3 (en) 2005-09-26 2013-04-24 Medarex, Inc. Conjugates of duocarmycin and anti-CD70 or anti-PSMA antibodies
RS52100B (sr) 2005-10-26 2012-06-30 Medarex, Inc. Postupci i jedinjenja za pripremu analoga cc-1065
WO2007059404A2 (en) 2005-11-10 2007-05-24 Medarex, Inc. Duocarmycin derivatives as novel cytotoxic compounds and conjugates
US7608693B2 (en) * 2006-10-02 2009-10-27 Regeneron Pharmaceuticals, Inc. High affinity human antibodies to human IL-4 receptor
MY149079A (en) * 2006-10-02 2013-07-15 Regeneron Pharma High affinity human antibodies to human il-4 receptor
TWI412367B (zh) 2006-12-28 2013-10-21 梅達雷克斯有限責任公司 化學鏈接劑與可裂解基質以及其之綴合物
AR065404A1 (es) 2007-02-21 2009-06-03 Medarex Inc Conjugados farmaco-ligando, los que se unen a citotoxinas potentes, composicion farmaceutica que los contienen y su uso para retardar o detener el crecimiento de un tumor en un mamifero
WO2009121847A2 (en) * 2008-04-02 2009-10-08 Apogenix Gmbh Binding agents directed against il-4 receptor for the treatment of tumors, inflammatory and immunological disorders
US8986691B1 (en) * 2014-07-15 2015-03-24 Kymab Limited Method of treating atopic dermatitis or asthma using antibody to IL4RA
US8980273B1 (en) * 2014-07-15 2015-03-17 Kymab Limited Method of treating atopic dermatitis or asthma using antibody to IL4RA
CA2959571A1 (en) * 2014-09-03 2016-03-10 Medimmune Limited Stable anti-il-4r-alpha antibody formulation
CN108409860B (zh) * 2017-02-10 2021-10-15 三生国健药业(上海)股份有限公司 抗人白细胞介素-4受体α单克隆抗体、其制备方法和应用

Similar Documents

Publication Publication Date Title
JP2023515223A5 (https=)
CN110799539B (zh) 抗4-1bb抗体及其制备和使用方法
CN107922503B (zh) 一种pdl-1抗体、其药物组合物及其用途
JP2025138634A (ja) B細胞成熟抗原を標的にする多重特異性抗体のための投与計画及び組み合わせ治療
JP2020520665A5 (https=)
JP2022543387A5 (https=)
JP2019536806A5 (https=)
JP2019529373A5 (ja) 抗Tim−3抗体
JP2019536430A5 (https=)
JP2020501531A5 (https=)
JP2018183173A5 (https=)
JP2022533418A5 (https=)
JP2019527194A5 (https=)
JP2011509245A5 (https=)
JP2018505177A5 (https=)
JP2017530722A5 (https=)
HRP20200652T1 (hr) Ljudska antitijela na fel d1 i metode njihove primjene
JP2017529838A5 (https=)
JP2020514277A5 (https=)
JP2022514179A5 (https=)
JP2019511911A5 (https=)
JP2019534710A5 (https=)
JP2023518153A5 (https=)
JP2022521705A (ja) 抗clec2d抗体及びその使用方法
JP2024541680A5 (https=)