JP2023514148A5 - - Google Patents
Info
- Publication number
- JP2023514148A5 JP2023514148A5 JP2022547960A JP2022547960A JP2023514148A5 JP 2023514148 A5 JP2023514148 A5 JP 2023514148A5 JP 2022547960 A JP2022547960 A JP 2022547960A JP 2022547960 A JP2022547960 A JP 2022547960A JP 2023514148 A5 JP2023514148 A5 JP 2023514148A5
- Authority
- JP
- Japan
- Prior art keywords
- seq
- car according
- mutant
- amino acid
- acid sequence
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2025042378A JP2025085754A (ja) | 2020-02-05 | 2025-03-17 | Ｃｄ２８変異を有するキメラ抗原受容体およびその使用 |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202062970401P | 2020-02-05 | 2020-02-05 | |
| US62/970,401 | 2020-02-05 | ||
| PCT/US2021/016713 WO2021158850A1 (en) | 2020-02-05 | 2021-02-05 | Chimeric antigen receptors with cd28 mutations and use thereof |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2025042378A Division JP2025085754A (ja) | 2020-02-05 | 2025-03-17 | Ｃｄ２８変異を有するキメラ抗原受容体およびその使用 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2023514148A JP2023514148A (ja) | 2023-04-05 |
| JP2023514148A5 true JP2023514148A5 (enExample) | 2024-02-02 |
| JP7698655B2 JP7698655B2 (ja) | 2025-06-25 |
Family
ID=77200355
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022547960A Active JP7698655B2 (ja) | 2020-02-05 | 2021-02-05 | Ｃｄ２８変異を有するキメラ抗原受容体およびその使用 |
| JP2025042378A Pending JP2025085754A (ja) | 2020-02-05 | 2025-03-17 | Ｃｄ２８変異を有するキメラ抗原受容体およびその使用 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2025042378A Pending JP2025085754A (ja) | 2020-02-05 | 2025-03-17 | Ｃｄ２８変異を有するキメラ抗原受容体およびその使用 |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US20230051064A1 (enExample) |
| EP (1) | EP4100025A4 (enExample) |
| JP (2) | JP7698655B2 (enExample) |
| KR (1) | KR20220138388A (enExample) |
| CN (1) | CN115397461A (enExample) |
| AU (1) | AU2021216450A1 (enExample) |
| BR (1) | BR112022015529A2 (enExample) |
| CA (1) | CA3170706A1 (enExample) |
| IL (2) | IL327298A (enExample) |
| MX (1) | MX2022009704A (enExample) |
| WO (1) | WO2021158850A1 (enExample) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA3230627A1 (en) * | 2021-09-02 | 2023-03-09 | Memorial Sloan-Kettering Cancer Center | Antigen recognizing receptors targeting dll3 and uses thereof |
| CN114031690B (zh) * | 2021-12-03 | 2022-07-15 | 广州百暨基因科技有限公司 | 靶向ccr1和nkg2d配体的嵌合抗原受体及其应用 |
| WO2024121796A1 (en) | 2022-12-07 | 2024-06-13 | Fondazione Matilde Tettamanti E Menotti De Marchi Onlus | Methods for generating genetically modified cytokine induced killer (cik) cells |
| EP4382118B1 (en) * | 2022-12-07 | 2025-08-20 | Eberhard Karls Universität Tübingen, Medizinische Fakultät | Modified immune cell |
| WO2025084881A1 (ko) * | 2023-10-20 | 2025-04-24 | 주식회사 이온셀 | Ct83 항원에 결합하는 car-t 세포 및 이의 용도 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5525503A (en) * | 1993-09-28 | 1996-06-11 | Dana-Farber Cancer Institute, Inc. | Signal transduction via CD28 |
| US7229960B2 (en) * | 2000-11-03 | 2007-06-12 | University Of Vermont And State Agricultural College | Methods and compositions for inhibiting GRB7 |
| US9096663B2 (en) * | 2001-02-15 | 2015-08-04 | The Board Of Trustees Of The University Of Illinois | Compositions and methods for treating conditions related to ephrin signaling with cupredoxins and mutants thereof |
| WO2011119484A1 (en) * | 2010-03-23 | 2011-09-29 | Iogenetics, Llc | Bioinformatic processes for determination of peptide binding |
| WO2017176525A1 (en) * | 2016-04-04 | 2017-10-12 | Promab Biotechnologies, Inc. | Car having replicated binding motifs in a co-stimulatory domain |
| US11535662B2 (en) * | 2017-01-26 | 2022-12-27 | Novartis Ag | CD28 compositions and methods for chimeric antigen receptor therapy |
| CN111212663A (zh) * | 2017-07-07 | 2020-05-29 | H·李·莫菲特癌症中心研究所公司 | 具有突变的cd28共刺激性结构域的嵌合抗原受体 |
-
2021
- 2021-02-04 IL IL327298A patent/IL327298A/en unknown
- 2021-02-05 CN CN202180025555.XA patent/CN115397461A/zh active Pending
- 2021-02-05 JP JP2022547960A patent/JP7698655B2/ja active Active
- 2021-02-05 AU AU2021216450A patent/AU2021216450A1/en active Pending
- 2021-02-05 WO PCT/US2021/016713 patent/WO2021158850A1/en not_active Ceased
- 2021-02-05 BR BR112022015529A patent/BR112022015529A2/pt unknown
- 2021-02-05 MX MX2022009704A patent/MX2022009704A/es unknown
- 2021-02-05 KR KR1020227029292A patent/KR20220138388A/ko active Pending
- 2021-02-05 CA CA3170706A patent/CA3170706A1/en active Pending
- 2021-02-05 EP EP21751385.2A patent/EP4100025A4/en active Pending
-
2022
- 2022-08-05 IL IL295405A patent/IL295405B2/en unknown
- 2022-08-05 US US17/817,735 patent/US20230051064A1/en active Pending
-
2025
- 2025-03-17 JP JP2025042378A patent/JP2025085754A/ja active Pending