KR20220138388A - Cd28 돌연변이를 갖는 키메라 항원 수용체 및 그의 용도 - Google Patents

Cd28 돌연변이를 갖는 키메라 항원 수용체 및 그의 용도 Download PDF

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KR20220138388A
KR20220138388A KR1020227029292A KR20227029292A KR20220138388A KR 20220138388 A KR20220138388 A KR 20220138388A KR 1020227029292 A KR1020227029292 A KR 1020227029292A KR 20227029292 A KR20227029292 A KR 20227029292A KR 20220138388 A KR20220138388 A KR 20220138388A
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seq
car
gly
ser
cells
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앤서니 다니얀
레니어 제이. 브렌트젠스
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메모리얼 슬로안 케터링 캔서 센터
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KR1020227029292A 2020-02-05 2021-02-05 Cd28 돌연변이를 갖는 키메라 항원 수용체 및 그의 용도 Pending KR20220138388A (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202062970401P 2020-02-05 2020-02-05
US62/970,401 2020-02-05
PCT/US2021/016713 WO2021158850A1 (en) 2020-02-05 2021-02-05 Chimeric antigen receptors with cd28 mutations and use thereof

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KR20220138388A true KR20220138388A (ko) 2022-10-12

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KR1020227029292A Pending KR20220138388A (ko) 2020-02-05 2021-02-05 Cd28 돌연변이를 갖는 키메라 항원 수용체 및 그의 용도

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US (1) US20230051064A1 (enExample)
EP (1) EP4100025A4 (enExample)
JP (2) JP7698655B2 (enExample)
KR (1) KR20220138388A (enExample)
CN (1) CN115397461A (enExample)
AU (1) AU2021216450A1 (enExample)
BR (1) BR112022015529A2 (enExample)
CA (1) CA3170706A1 (enExample)
IL (2) IL327298A (enExample)
MX (1) MX2022009704A (enExample)
WO (1) WO2021158850A1 (enExample)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA3230627A1 (en) * 2021-09-02 2023-03-09 Memorial Sloan-Kettering Cancer Center Antigen recognizing receptors targeting dll3 and uses thereof
CN114031690B (zh) * 2021-12-03 2022-07-15 广州百暨基因科技有限公司 靶向ccr1和nkg2d配体的嵌合抗原受体及其应用
WO2024121796A1 (en) 2022-12-07 2024-06-13 Fondazione Matilde Tettamanti E Menotti De Marchi Onlus Methods for generating genetically modified cytokine induced killer (cik) cells
EP4382118B1 (en) * 2022-12-07 2025-08-20 Eberhard Karls Universität Tübingen, Medizinische Fakultät Modified immune cell
WO2025084881A1 (ko) * 2023-10-20 2025-04-24 주식회사 이온셀 Ct83 항원에 결합하는 car-t 세포 및 이의 용도

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5525503A (en) * 1993-09-28 1996-06-11 Dana-Farber Cancer Institute, Inc. Signal transduction via CD28
US7229960B2 (en) * 2000-11-03 2007-06-12 University Of Vermont And State Agricultural College Methods and compositions for inhibiting GRB7
US9096663B2 (en) * 2001-02-15 2015-08-04 The Board Of Trustees Of The University Of Illinois Compositions and methods for treating conditions related to ephrin signaling with cupredoxins and mutants thereof
WO2011119484A1 (en) * 2010-03-23 2011-09-29 Iogenetics, Llc Bioinformatic processes for determination of peptide binding
WO2017176525A1 (en) * 2016-04-04 2017-10-12 Promab Biotechnologies, Inc. Car having replicated binding motifs in a co-stimulatory domain
US11535662B2 (en) * 2017-01-26 2022-12-27 Novartis Ag CD28 compositions and methods for chimeric antigen receptor therapy
CN111212663A (zh) * 2017-07-07 2020-05-29 H·李·莫菲特癌症中心研究所公司 具有突变的cd28共刺激性结构域的嵌合抗原受体

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MX2022009704A (es) 2022-11-08
AU2021216450A1 (en) 2022-09-08
EP4100025A4 (en) 2025-03-05
EP4100025A1 (en) 2022-12-14
US20230051064A1 (en) 2023-02-16
IL327298A (en) 2026-05-01
IL295405B2 (en) 2026-08-01
IL295405B1 (en) 2026-04-01
JP2023514148A (ja) 2023-04-05
CN115397461A (zh) 2022-11-25
CA3170706A1 (en) 2021-08-12
IL295405A (en) 2022-10-01
JP7698655B2 (ja) 2025-06-25
WO2021158850A1 (en) 2021-08-12
BR112022015529A2 (pt) 2022-12-13
JP2025085754A (ja) 2025-06-05

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