JP2023513906A5 - - Google Patents

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Publication number
JP2023513906A5
JP2023513906A5 JP2022548997A JP2022548997A JP2023513906A5 JP 2023513906 A5 JP2023513906 A5 JP 2023513906A5 JP 2022548997 A JP2022548997 A JP 2022548997A JP 2022548997 A JP2022548997 A JP 2022548997A JP 2023513906 A5 JP2023513906 A5 JP 2023513906A5
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JP
Japan
Prior art keywords
group
compound
tautomer
salt
formula
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Application number
JP2022548997A
Other languages
English (en)
Japanese (ja)
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JP2023513906A (ja
JP7686002B2 (ja
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Application filed filed Critical
Priority claimed from PCT/EP2021/053284 external-priority patent/WO2021160716A1/en
Publication of JP2023513906A publication Critical patent/JP2023513906A/ja
Publication of JP2023513906A5 publication Critical patent/JP2023513906A5/ja
Application granted granted Critical
Publication of JP7686002B2 publication Critical patent/JP7686002B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

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JP2022548997A 2020-02-13 2021-02-11 血漿カリクレイン阻害剤としての複素芳香族カルボキサミド誘導体 Active JP7686002B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP20157257 2020-02-13
EP20157257.5 2020-02-13
PCT/EP2021/053284 WO2021160716A1 (en) 2020-02-13 2021-02-11 Heteroaromatic carboxamide derivatives as plasma kallikrein inhibitors

Publications (3)

Publication Number Publication Date
JP2023513906A JP2023513906A (ja) 2023-04-04
JP2023513906A5 true JP2023513906A5 (https=) 2024-01-26
JP7686002B2 JP7686002B2 (ja) 2025-05-30

Family

ID=69591570

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2022548997A Active JP7686002B2 (ja) 2020-02-13 2021-02-11 血漿カリクレイン阻害剤としての複素芳香族カルボキサミド誘導体

Country Status (7)

Country Link
US (1) US11851418B2 (https=)
EP (1) EP4103561A1 (https=)
JP (1) JP7686002B2 (https=)
CN (1) CN115087652B (https=)
AR (1) AR121340A1 (https=)
TW (1) TW202144331A (https=)
WO (1) WO2021160716A1 (https=)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112839711A (zh) 2018-10-10 2021-05-25 勃林格殷格翰国际有限公司 作为血浆激肽释放酶抑制剂的苯基四唑衍生物
TWI873290B (zh) 2020-02-13 2025-02-21 德商百靈佳殷格翰國際股份有限公司 作為血漿激肽釋放酶抑制劑之雜芳族甲醯胺衍生物
TW202144331A (zh) 2020-02-13 2021-12-01 德商百靈佳殷格翰國際股份有限公司 作為血漿激肽釋放酶抑制劑之雜芳族甲醯胺衍生物

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI243164B (en) 2001-02-13 2005-11-11 Aventis Pharma Gmbh Acylated indanyl amines and their use as pharmaceuticals
US20050090529A1 (en) 2003-07-31 2005-04-28 Pfizer Inc 3,5 Disubstituted indazole compounds with nitrogen-bearing 5-membered heterocycles, pharmaceutical compositions, and methods for mediating or inhibiting cell proliferation
JP2005089362A (ja) 2003-09-17 2005-04-07 Sumitomo Chemical Co Ltd アリールピラゾリン化合物及びその用途
EP2259679A4 (en) 2008-01-31 2011-09-14 Joslin Diabetes Ct METHODS OF TREATING KALLIKREIN RELATED DISORDERS
EP2807156A1 (en) 2012-01-27 2014-12-03 Novartis AG Aminopyridine derivatives as plasma kallikrein inhibitors
US20140378474A1 (en) 2012-01-27 2014-12-25 Novartis Ag 5-membered heteroarylcarboxamide derivatives as plasma kallikrein inhibitors
EP2999697B1 (en) 2013-05-23 2017-04-19 Kalvista Pharmaceuticals Limited Heterocyclic derivates
KR102736869B1 (ko) * 2014-03-07 2024-12-02 바이오크리스트파마슈티컬즈,인코포레이티드 인간 혈장 칼리크레인 저해제
GB201421083D0 (en) * 2014-11-27 2015-01-14 Kalvista Pharmaceuticals Ltd Enzyme inhibitors
DK4019022T3 (en) * 2015-10-01 2024-02-19 Biocryst Pharm Inc Human plasma kallikrein inhibitors
WO2017072020A1 (en) 2015-10-27 2017-05-04 Boehringer Ingelheim International Gmbh Heteroarylcarboxamide derivatives as plasma kallikrein inhibitors
EP3368524B1 (en) 2015-10-27 2021-08-18 Boehringer Ingelheim International GmbH Heteroarylcarboxamide derivatives as plasma kallikrein inhibitors
DK3464271T3 (da) 2016-05-31 2020-06-15 Kalvista Pharmaceuticals Ltd Pyrazolderivater som plasma-kallikreininhibitorer
CN110022875A (zh) 2016-07-11 2019-07-16 莱福斯希医药公司 治疗性抑制化合物
US10501440B2 (en) 2017-04-21 2019-12-10 Boehringer Ingelheim International Gmbh Heteroarylcarboxamide derivatives as plasma kallikrein inhibitors
JP6828191B2 (ja) * 2018-08-16 2021-02-10 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング 血漿カリクレイン阻害剤としての複素芳香族カルボキサミド誘導体
DK4031547T3 (da) * 2019-09-18 2024-09-09 Takeda Pharmaceuticals Co Plasmakallikreininhibitorer og anvendelser deraf
TW202144331A (zh) 2020-02-13 2021-12-01 德商百靈佳殷格翰國際股份有限公司 作為血漿激肽釋放酶抑制劑之雜芳族甲醯胺衍生物
TWI873290B (zh) 2020-02-13 2025-02-21 德商百靈佳殷格翰國際股份有限公司 作為血漿激肽釋放酶抑制劑之雜芳族甲醯胺衍生物

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