JP2023513738A5 - - Google Patents
Info
- Publication number
- JP2023513738A5 JP2023513738A5 JP2022548876A JP2022548876A JP2023513738A5 JP 2023513738 A5 JP2023513738 A5 JP 2023513738A5 JP 2022548876 A JP2022548876 A JP 2022548876A JP 2022548876 A JP2022548876 A JP 2022548876A JP 2023513738 A5 JP2023513738 A5 JP 2023513738A5
- Authority
- JP
- Japan
- Prior art keywords
- compounds
- compound
- contacting
- produced
- base
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202062977004P | 2020-02-14 | 2020-02-14 | |
| US62/977,004 | 2020-02-14 | ||
| US202163144902P | 2021-02-02 | 2021-02-02 | |
| US63/144,902 | 2021-02-02 | ||
| PCT/IB2021/000130 WO2021161109A1 (en) | 2020-02-14 | 2021-02-12 | Preparation of a p2x3 antagonist |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2023513738A JP2023513738A (ja) | 2023-04-03 |
| JP2023513738A5 true JP2023513738A5 (https=) | 2024-02-20 |
| JP7693691B2 JP7693691B2 (ja) | 2025-06-17 |
Family
ID=77292130
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022548876A Active JP7693691B2 (ja) | 2020-02-14 | 2021-02-12 | Ｐ２ｘ３アンタゴニストの製造 |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US12503470B2 (https=) |
| EP (1) | EP4103572A4 (https=) |
| JP (1) | JP7693691B2 (https=) |
| KR (1) | KR20220140804A (https=) |
| CN (1) | CN115427419B (https=) |
| AU (1) | AU2021219992A1 (https=) |
| BR (1) | BR112022015818A2 (https=) |
| CA (1) | CA3184277A1 (https=) |
| IL (1) | IL295394A (https=) |
| MX (1) | MX2022009765A (https=) |
| WO (1) | WO2021161109A1 (https=) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP7578602B2 (ja) | 2019-02-25 | 2024-11-06 | グラクソスミスクライン、インテレクチュアル、プロパティー、（ナンバー３）、リミテッド | Ｐ２ｘ３修飾薬での治療 |
| WO2022156783A1 (zh) * | 2021-01-22 | 2022-07-28 | 武汉人福创新药物研发中心有限公司 | 咪唑并吡啶类化合物的制备方法及其中间体 |
| CN114805237B (zh) * | 2021-01-22 | 2026-04-21 | 武汉人福创新药物研发中心有限公司 | 杂环类化合物的制备方法及其中间体 |
| WO2022161462A1 (zh) * | 2021-01-29 | 2022-08-04 | 上海海雁医药科技有限公司 | 吗啉衍生物及其药物组合物和用途 |
| WO2023021328A1 (en) * | 2021-08-17 | 2023-02-23 | Bellus Health Cough Inc. | Preparation of a p2x3 antagonist |
| EP4577528A1 (en) * | 2022-08-25 | 2025-07-02 | 14245563 Canada Inc. | Preparation of a p2x3 antagonist |
| WO2025125445A1 (en) | 2023-12-12 | 2025-06-19 | Glaxosmithkline Intellectual Property (No.3) Limited | Process of manufacture of p2x3 antagonists including camlipixant |
| WO2025191081A1 (en) | 2024-03-15 | 2025-09-18 | Glaxosmithkline Intellectual Property (No.3) Limited | Crystalline form of camlipixant |
| WO2026022326A1 (en) | 2024-07-25 | 2026-01-29 | Glaxosmithkline Intellectual Property (No.3) Limited | P2x3 antagonist formulation |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2010229142A1 (en) * | 2009-03-23 | 2011-10-13 | Merck Sharp & Dohme Corp. | P2X3, receptor antagonists for treatment of pain |
| CN102358739B (zh) * | 2011-04-29 | 2013-02-20 | 中国科学院广州生物医药与健康研究院 | 咪唑[1,2-a]吡啶和咪唑醛类化合物的合成方法 |
| DK3381917T3 (da) * | 2013-01-31 | 2021-10-18 | Bellus Health Cough Inc | Imidazopyridinforbindelser og anvendelser deraf |
| US10111883B1 (en) | 2017-09-18 | 2018-10-30 | Bellus Health Cough Inc. | Selective P2X3 modulators |
| KR102797127B1 (ko) * | 2018-12-29 | 2025-04-21 | 우한 크리에이터나 사이언스 앤드 테크놀로지 컴퍼니, 리미티드 | 헤테로고리계 화합물, 중간체, 이의 제조 방법 및 용도 |
| EP4103564A4 (en) * | 2020-02-14 | 2024-05-01 | GlaxoSmithKline Intellectual Property (No.3) Limited | P2X3 MODULATORS |
| WO2021244634A1 (zh) | 2020-06-05 | 2021-12-09 | 武汉人福创新药物研发中心有限公司 | 咪唑并吡啶类化合物及其用途 |
| EP4169921A4 (en) | 2020-06-29 | 2024-06-19 | Wuhan LL Science and Technology Development Co., Ltd. | Crystalline form of heterocyclic compound, preparation method therefor and application thereof |
| WO2022156783A1 (zh) | 2021-01-22 | 2022-07-28 | 武汉人福创新药物研发中心有限公司 | 咪唑并吡啶类化合物的制备方法及其中间体 |
| CN114805237B (zh) | 2021-01-22 | 2026-04-21 | 武汉人福创新药物研发中心有限公司 | 杂环类化合物的制备方法及其中间体 |
-
2021
- 2021-02-12 CN CN202180028877.XA patent/CN115427419B/zh active Active
- 2021-02-12 JP JP2022548876A patent/JP7693691B2/ja active Active
- 2021-02-12 EP EP21754068.1A patent/EP4103572A4/en active Pending
- 2021-02-12 WO PCT/IB2021/000130 patent/WO2021161109A1/en not_active Ceased
- 2021-02-12 US US17/929,027 patent/US12503470B2/en active Active
- 2021-02-12 AU AU2021219992A patent/AU2021219992A1/en not_active Abandoned
- 2021-02-12 IL IL295394A patent/IL295394A/en unknown
- 2021-02-12 BR BR112022015818A patent/BR112022015818A2/pt unknown
- 2021-02-12 CA CA3184277A patent/CA3184277A1/en active Pending
- 2021-02-12 MX MX2022009765A patent/MX2022009765A/es unknown
- 2021-02-12 KR KR1020227031508A patent/KR20220140804A/ko active Pending
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