JP2023513013A5 - - Google Patents

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Publication number
JP2023513013A5
JP2023513013A5 JP2022545994A JP2022545994A JP2023513013A5 JP 2023513013 A5 JP2023513013 A5 JP 2023513013A5 JP 2022545994 A JP2022545994 A JP 2022545994A JP 2022545994 A JP2022545994 A JP 2022545994A JP 2023513013 A5 JP2023513013 A5 JP 2023513013A5
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JP
Japan
Prior art keywords
iacs
cancer
nrg1
fusion
quinazoline
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JP2022545994A
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English (en)
Japanese (ja)
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JP2023513013A (ja
JP7734139B2 (ja
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Priority claimed from PCT/US2021/015704 external-priority patent/WO2021155144A1/en
Publication of JP2023513013A publication Critical patent/JP2023513013A/ja
Publication of JP2023513013A5 publication Critical patent/JP2023513013A5/ja
Application granted granted Critical
Publication of JP7734139B2 publication Critical patent/JP7734139B2/ja
Active legal-status Critical Current
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JP2022545994A 2020-01-29 2021-01-29 Nrg1融合体を有するがんの治療のためのキナゾリンベースのチロシンキナーゼインヒビターの使用 Active JP7734139B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202062967282P 2020-01-29 2020-01-29
US62/967,282 2020-01-29
PCT/US2021/015704 WO2021155144A1 (en) 2020-01-29 2021-01-29 Use of quinazoline-based tyrosine kinase inhibitors for the treatment of cancers with nrg1 fusions

Publications (3)

Publication Number Publication Date
JP2023513013A JP2023513013A (ja) 2023-03-30
JP2023513013A5 true JP2023513013A5 (https=) 2024-01-17
JP7734139B2 JP7734139B2 (ja) 2025-09-04

Family

ID=77079970

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2022545994A Active JP7734139B2 (ja) 2020-01-29 2021-01-29 Nrg1融合体を有するがんの治療のためのキナゾリンベースのチロシンキナーゼインヒビターの使用

Country Status (7)

Country Link
US (1) US20230121116A1 (https=)
EP (1) EP4097140A4 (https=)
JP (1) JP7734139B2 (https=)
KR (1) KR20220133927A (https=)
CN (1) CN115427456A (https=)
CA (1) CA3166298A1 (https=)
WO (1) WO2021155144A1 (https=)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2024523001A (ja) * 2021-06-03 2024-06-25 メルス ナムローゼ フェンノートシャップ 新たなnrg1融合体、融合接合部及びそれらを検出するための方法
WO2022266426A1 (en) * 2021-06-17 2022-12-22 Black Diamond Therapeutics, Inc. 6-(heterocycloalkyl-oxy)-quinazoline derivatives and uses thereof

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI377944B (en) * 2007-06-05 2012-12-01 Hanmi Holdings Co Ltd Novel amide derivative for inhibiting the growth of cancer cells
WO2009042618A1 (en) * 2007-09-24 2009-04-02 Tragara Pharmaceuticals, Inc. Therapies for treating cancer using combinations of cox-2 inhibitors and anti-her2(erbb2) antibodies or combinations of cox-2 inhibitors and her2(erbb2) receptor tyrosine kinase inhibitors
CN103547598A (zh) 2011-02-24 2014-01-29 梅里麦克制药股份有限公司 包含抗-erbb3药剂的联合治疗
WO2013113796A1 (en) 2012-01-31 2013-08-08 Smithkline Beecham (Cork) Limited Method of treating cancer
EP2924045A1 (en) * 2014-03-25 2015-09-30 Medizinische Universität Wien New agents for the treatment of cancer
WO2016201454A1 (en) * 2015-06-12 2016-12-15 The Translational Genomics Research Institute Targeted therapies for cancer
KR102771603B1 (ko) * 2016-11-17 2025-02-24 더 보드 오브 리젠츠 오브 더 유니버시티 오브 텍사스 시스템 Egfr 또는 her2 엑손 20 돌연변이를 갖는 암 세포에 대한 항종양 활성을 갖는 화합물
EP3679063A4 (en) * 2017-09-08 2021-06-02 The Regents of The University of Colorado, A Body Corporate COMPOUNDS, COMPOSITIONS, AND METHODS FOR TREATMENT OR PREVENTION OF HER-CONTROLLED DRUG-RESISTANT CANCER
CN112040952B (zh) * 2018-02-20 2023-03-31 苏州韬略生物科技股份有限公司 用作激酶抑制剂的取代的喹啉
KR20210025064A (ko) * 2018-06-25 2021-03-08 스펙트럼 파마슈티컬즈 인크 항-her1, her2 또는 her4 항체와 포지오티닙의 조합물 및 이의 사용 방법
JP7777533B2 (ja) * 2020-01-29 2025-11-28 ボード オブ リージェンツ,ザ ユニバーシティ オブ テキサス システム Nrg1融合体を有するがんの治療のためのポジオチニブの使用

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