JP2023511992A5 - - Google Patents
Info
- Publication number
- JP2023511992A5 JP2023511992A5 JP2022545423A JP2022545423A JP2023511992A5 JP 2023511992 A5 JP2023511992 A5 JP 2023511992A5 JP 2022545423 A JP2022545423 A JP 2022545423A JP 2022545423 A JP2022545423 A JP 2022545423A JP 2023511992 A5 JP2023511992 A5 JP 2023511992A5
- Authority
- JP
- Japan
- Prior art keywords
- cldna
- dna
- nucleotide
- nucleotides
- modified
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2025137441A JP2025186257A (ja) | 2020-01-31 | 2025-08-21 | 修飾ヌクレオチドを用いた閉じた直鎖ｄｎａ |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP20382063 | 2020-01-31 | ||
| EP20382063.4 | 2020-01-31 | ||
| PCT/EP2021/052204 WO2021152147A1 (en) | 2020-01-31 | 2021-01-29 | Closed linear dna with modified nucleotides |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2025137441A Division JP2025186257A (ja) | 2020-01-31 | 2025-08-21 | 修飾ヌクレオチドを用いた閉じた直鎖ｄｎａ |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2023511992A JP2023511992A (ja) | 2023-03-23 |
| JP2023511992A5 true JP2023511992A5 (enExample) | 2024-02-05 |
Family
ID=69713977
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022545423A Pending JP2023511992A (ja) | 2020-01-31 | 2021-01-29 | 修飾ヌクレオチドを用いた閉じた直鎖ｄｎａ |
| JP2025137441A Pending JP2025186257A (ja) | 2020-01-31 | 2025-08-21 | 修飾ヌクレオチドを用いた閉じた直鎖ｄｎａ |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2025137441A Pending JP2025186257A (ja) | 2020-01-31 | 2025-08-21 | 修飾ヌクレオチドを用いた閉じた直鎖ｄｎａ |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US20230323343A1 (enExample) |
| EP (1) | EP4097253A1 (enExample) |
| JP (2) | JP2023511992A (enExample) |
| KR (1) | KR20220133999A (enExample) |
| CN (1) | CN115003829A (enExample) |
| AU (1) | AU2021213927A1 (enExample) |
| CA (1) | CA3164390A1 (enExample) |
| WO (1) | WO2021152147A1 (enExample) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP4083227A1 (en) * | 2021-04-29 | 2022-11-02 | 4basebio, S.L.U. | Linear dna with enhanced resistance against exonucleases |
| EP4124660A1 (en) * | 2021-07-30 | 2023-02-01 | 4basebio, S.L.U. | Linear dna with enhanced resistance against exonucleases and methods for the production thereof |
| WO2023023285A2 (en) | 2021-08-19 | 2023-02-23 | Twist Bioscience Corporation | Methods and compositions relating to covalently closed nucleic acids |
| CN114075595B (zh) * | 2021-11-22 | 2023-11-17 | 上海交通大学 | 甲基化检测组合物、试剂盒及方法 |
| IL314724A (en) * | 2022-02-10 | 2024-10-01 | Code Biotherapeutics Inc | Improved DNA dendrimers and methods of using them |
| TW202409283A (zh) * | 2022-05-13 | 2024-03-01 | 美商旗艦先鋒創新有限責任（Ｖｉｉ）公司 | 雙股ｄｎａ組合物及相關方法 |
| CN115976138A (zh) * | 2022-06-02 | 2023-04-18 | 宜明(苏州)细胞生物科技有限公司 | 新型闭合线性双链dna的体外制备技术 |
| WO2024039652A1 (en) | 2022-08-16 | 2024-02-22 | Aldevron, L.L.C. | Cell-free method of producing synthetic circular nucleic acid |
| EP4410992B1 (en) * | 2023-02-01 | 2025-12-17 | 4basebio UK Ltd | Linear dna with enhanced resistance against exonucleases and methods for the production thereof |
| EP4410995A1 (en) * | 2023-02-01 | 2024-08-07 | 4basebio, S.L.U. | Linear dna with enhanced resistance against exonucleases and methods for the production thereof |
| WO2025034978A1 (en) * | 2023-08-09 | 2025-02-13 | Code Biotherapeutics, Inc. | Enhanced dna dendrimers and methods of use thereof |
| WO2025064396A1 (en) * | 2023-09-18 | 2025-03-27 | Intellia Therapeutics, Inc. | Nuclease resistant double stranded dna product for non-viral delivery to a cell and methods of production thereof |
| WO2025096807A2 (en) * | 2023-10-31 | 2025-05-08 | Flagship Pioneering Innovations Vii, Llc | Novel therapeutic dna forms |
| WO2025202929A1 (en) * | 2024-03-29 | 2025-10-02 | Pfizer Inc. | Methods for producing nucleic acids |
| EP4663200A1 (en) * | 2024-06-10 | 2025-12-17 | CPTx GmbH | Compositions and methods |
| WO2026012450A1 (zh) * | 2024-07-11 | 2026-01-15 | 石药集团中奇制药技术（石家庄）有限公司 | 一种非病毒载体介导的大片段dna定点敲入系统 |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4373071A (en) | 1981-04-30 | 1983-02-08 | City Of Hope Research Institute | Solid-phase synthesis of polynucleotides |
| US7972816B2 (en) * | 2003-08-08 | 2011-07-05 | National Institute Of Advanced Industrial Science And Technology | Efficient process for producing dumbbell DNA |
| DK1716234T3 (da) * | 2004-02-20 | 2014-01-20 | Mologen Ag | Substitueret, ikke-kodende nukleinsyremolekyle til terapeutisk og profylaktisk immunstimulering i mennesker og højerestående dyr |
| EP1859812B1 (en) | 2005-02-10 | 2014-01-01 | The University of Tokyo | Polycation chargeable polymer and use as carrier of nucleic acid |
| ES2359058B1 (es) | 2009-07-02 | 2012-03-27 | Consejo Superior De Investigaciones Cient�?Ficas (Csic) | Quimera de adn polimerasa del fago ph1 29. |
| GB2523187A (en) * | 2014-02-18 | 2015-08-19 | Mologen Ag | Covalently closed non-coding immunomodulatory DNA construct |
| WO2015157747A1 (en) * | 2014-04-11 | 2015-10-15 | Redvault Biosciences Lp | Systems and methods for clonal replication and amplification of nucleic acid molecules for genomic and therapeutic applications |
| GB201418159D0 (en) * | 2014-10-14 | 2014-11-26 | Oxford Nanopore Tech Ltd | Method |
| US11505821B2 (en) * | 2016-08-16 | 2022-11-22 | Touchlight IP Limited | Closed linear DNA production |
| WO2018213460A1 (en) * | 2017-05-16 | 2018-11-22 | Helix Nanotechnologies, Inc. | Linear covalently closed vectors and related compositions and methods thereof |
| AU2018371063C1 (en) * | 2017-11-21 | 2025-04-17 | 4basebio Sl | Methods and kits for amplification of double stranded DNA |
-
2021
- 2021-01-29 AU AU2021213927A patent/AU2021213927A1/en active Pending
- 2021-01-29 WO PCT/EP2021/052204 patent/WO2021152147A1/en not_active Ceased
- 2021-01-29 JP JP2022545423A patent/JP2023511992A/ja active Pending
- 2021-01-29 CN CN202180011940.9A patent/CN115003829A/zh active Pending
- 2021-01-29 EP EP21703640.9A patent/EP4097253A1/en active Pending
- 2021-01-29 US US17/796,532 patent/US20230323343A1/en active Pending
- 2021-01-29 CA CA3164390A patent/CA3164390A1/en active Pending
- 2021-01-29 KR KR1020227030065A patent/KR20220133999A/ko active Pending
-
2025
- 2025-08-21 JP JP2025137441A patent/JP2025186257A/ja active Pending
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