JP2023510219A5 - - Google Patents
Info
- Publication number
- JP2023510219A5 JP2023510219A5 JP2022540871A JP2022540871A JP2023510219A5 JP 2023510219 A5 JP2023510219 A5 JP 2023510219A5 JP 2022540871 A JP2022540871 A JP 2022540871A JP 2022540871 A JP2022540871 A JP 2022540871A JP 2023510219 A5 JP2023510219 A5 JP 2023510219A5
- Authority
- JP
- Japan
- Prior art keywords
- human insulin
- γglu
- desb30 human
- eicosanedioyl
- insulin
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201911398378 | 2019-12-30 | ||
| CN201911398378.0 | 2019-12-30 | ||
| CN202011057926.6 | 2020-09-29 | ||
| CN202011057926 | 2020-09-29 | ||
| PCT/CN2020/141023 WO2021136296A1 (zh) | 2019-12-30 | 2020-12-29 | 胰岛素衍生物 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2023510219A JP2023510219A (ja) | 2023-03-13 |
| JP2023510219A5 true JP2023510219A5 (enExample) | 2026-01-21 |
Family
ID=76687317
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022540871A Pending JP2023510219A (ja) | 2019-12-30 | 2020-12-29 | インスリン誘導体 |
| JP2022540767A Pending JP2023510206A (ja) | 2019-12-30 | 2020-12-29 | インスリン誘導体 |
| JP2025128114A Pending JP2025161829A (ja) | 2019-12-30 | 2025-07-31 | インスリン誘導体 |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022540767A Pending JP2023510206A (ja) | 2019-12-30 | 2020-12-29 | インスリン誘導体 |
| JP2025128114A Pending JP2025161829A (ja) | 2019-12-30 | 2025-07-31 | インスリン誘導体 |
Country Status (10)
| Country | Link |
|---|---|
| US (5) | US20240025957A1 (enExample) |
| EP (3) | EP4086278A4 (enExample) |
| JP (3) | JP2023510219A (enExample) |
| KR (2) | KR20220119730A (enExample) |
| CN (12) | CN118754967A (enExample) |
| AU (2) | AU2020418205A1 (enExample) |
| BR (2) | BR112022013150A2 (enExample) |
| CA (2) | CA3166495A1 (enExample) |
| MX (2) | MX2022008130A (enExample) |
| WO (3) | WO2021136293A1 (enExample) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN118754967A (zh) * | 2019-12-30 | 2024-10-11 | 甘李药业股份有限公司 | 胰岛素衍生物 |
| EP4086277A4 (en) * | 2019-12-30 | 2024-02-14 | Gan & Lee Pharmaceuticals Co., Ltd. | Long-acting glp-1 compound |
| CA3204051A1 (en) | 2021-01-20 | 2022-07-28 | Brian Lian | Compositions and methods for the treatment of metabolic and liver disorders |
| CN115385843A (zh) * | 2021-05-24 | 2022-11-25 | 广东东阳光药业有限公司 | 一种新型的酰化胰岛素类似物 |
| AU2022300061A1 (en) * | 2021-06-25 | 2024-02-01 | Gan & Lee Pharmaceuticals Co., Ltd. | Acylated insulin-containing pharmaceutical composition |
| JP7642830B2 (ja) | 2021-09-15 | 2025-03-10 | バイキング・セラピューティクス・インコーポレイテッド | 代謝及び肝臓障害の処置のための組成物及び方法 |
| CN116162147B (zh) * | 2021-11-24 | 2023-10-03 | 成都奥达生物科技有限公司 | 一种长效胰岛素类似物 |
| US20250340610A1 (en) * | 2022-01-28 | 2025-11-06 | Gan & Lee Pharmaceuticals Co., Ltd. | Acylated insulin |
| WO2024179606A1 (zh) * | 2023-03-02 | 2024-09-06 | 甘李药业股份有限公司 | 一种glp-1化合物的医药用途 |
| CN121219311A (zh) * | 2023-05-24 | 2025-12-26 | 联邦生物科技(珠海横琴)有限公司 | 一种胰岛素衍生物及其应用 |
| CN116327890B (zh) * | 2023-05-29 | 2023-12-08 | 北京先为达生物科技有限公司 | 口服递送的组合物及其应用 |
| CN116789801B (zh) * | 2023-08-21 | 2023-11-14 | 南京赛诺生物技术有限公司 | 新型胰岛素衍生物及其用途 |
| WO2025077751A1 (zh) * | 2023-10-09 | 2025-04-17 | 甘李药业股份有限公司 | Glp-1肽组合物及其用途 |
| WO2025098457A1 (zh) * | 2023-11-07 | 2025-05-15 | 甘李药业股份有限公司 | 用于降糖的酰化胰岛素 |
| WO2025098502A1 (zh) * | 2023-11-08 | 2025-05-15 | 甘李药业股份有限公司 | 包含胰岛素衍生物的药物组合物的治疗用途 |
| WO2025228255A1 (zh) * | 2024-04-28 | 2025-11-06 | 正大天晴药业集团股份有限公司 | 酰化人胰岛素类似物 |
Family Cites Families (37)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NZ199391A (en) | 1981-01-02 | 1985-12-13 | Genentech Inc | Chimeric polypeptides comprising a proinsulin sequence,and preparation by recombinant dna technique;production of human insulin |
| DK58285D0 (da) | 1984-05-30 | 1985-02-08 | Novo Industri As | Peptider samt fremstilling og anvendelse deraf |
| PH25772A (en) | 1985-08-30 | 1991-10-18 | Novo Industri As | Insulin analogues, process for their preparation |
| DK336188D0 (da) | 1988-06-20 | 1988-06-20 | Nordisk Gentofte | Propeptider |
| HUT56857A (en) | 1988-12-23 | 1991-10-28 | Novo Nordisk As | Human insulin analogues |
| IL93282A (en) | 1989-02-09 | 1995-08-31 | Lilly Co Eli | Insulin analogues |
| EP1132404A3 (en) | 1993-09-17 | 2002-03-27 | Novo Nordisk A/S | Acylated insulin |
| WO1995016708A1 (en) | 1993-12-17 | 1995-06-22 | Novo Nordisk A/S | Proinsulin-like compounds |
| US6500645B1 (en) | 1994-06-17 | 2002-12-31 | Novo Nordisk A/S | N-terminally extended proteins expressed in yeast |
| KR0150565B1 (ko) | 1995-02-15 | 1998-08-17 | 김정재 | 유전자 조환에 의한 사람 인슐린 전구체의 제조 및 이를 이용한 인슐린의 제조방법 |
| EP0741188A3 (en) | 1995-05-05 | 1999-07-14 | Eli Lilly And Company | Single chain insulin with high bioactivity |
| CA2531988C (en) | 2003-08-05 | 2016-06-28 | Novo Nordisk A/S | Novel insulin derivatives |
| DE602007009496D1 (de) * | 2006-02-27 | 2010-11-11 | Novo Nordisk As | Insulinderivate |
| EP2015770B1 (en) * | 2006-05-09 | 2012-09-26 | Novo Nordisk A/S | Insulin derivative |
| CN101573133B (zh) | 2006-07-31 | 2014-08-27 | 诺沃-诺迪斯克有限公司 | Peg化延长的胰岛素 |
| JP5688969B2 (ja) | 2007-07-16 | 2015-03-25 | ノボ・ノルデイスク・エー／エス | プロテアーゼに対して安定しているペグ化インスリンアナログ |
| JP5721432B2 (ja) * | 2007-08-15 | 2015-05-20 | ノボ・ノルデイスク・エー／エス | アミノ酸含有アルキレングリコール反復単位を含むアシル部を有するインスリン |
| US9150633B2 (en) | 2007-08-15 | 2015-10-06 | Novo Nordisk A/S | Insulin analogues with an acyl and alkylene glycol moiety |
| US20100292133A1 (en) | 2007-09-05 | 2010-11-18 | Novo Nordisk A/S | Truncated glp-1 derivaties and their therapeutical use |
| HUE032284T2 (en) * | 2008-03-18 | 2017-09-28 | Novo Nordisk As | Protease-stabilized, acylated insulin analogues |
| EP2552951A1 (en) | 2010-03-26 | 2013-02-06 | Novo Nordisk A/S | Novel glucagon analogues |
| CN103596584B (zh) * | 2011-06-15 | 2016-12-14 | 诺沃—诺迪斯克有限公司 | 多取代的胰岛素 |
| KR20140104994A (ko) | 2011-12-15 | 2014-08-29 | 샹하이 헨그루이 파마수티컬 컴퍼니 리미티드 | 인간 인슐린 유사체 및 이의 아실화 유도체 |
| CN104364260B (zh) | 2012-04-11 | 2017-02-22 | 诺和诺德股份有限公司 | 胰岛素制剂 |
| US20150111820A1 (en) | 2012-07-09 | 2015-04-23 | Novo Nordisk A/S | Novel use of insulin derivatives |
| JP2017506640A (ja) | 2014-02-14 | 2017-03-09 | セントローズ， エルエルシー | 細胞外標的化薬物共役体 |
| AR099569A1 (es) * | 2014-02-28 | 2016-08-03 | Novo Nordisk As | Derivados de insulina y los usos médicos de estos |
| CN105820233B (zh) | 2015-01-04 | 2021-06-15 | 甘李药业股份有限公司 | 一种胰岛素衍生物的制备方法 |
| WO2016119854A1 (en) | 2015-01-29 | 2016-08-04 | Novo Nordisk A/S | Pharmaceutical composition for oral insulin administration comprising a tablet core and a polyvinyl alcohol coating |
| ES2908373T3 (es) * | 2015-08-25 | 2022-04-28 | Novo Nordisk As | Nuevos derivados de insulina y los usos médicos de los mismos |
| PL3341991T3 (pl) * | 2015-08-27 | 2020-11-30 | Haldor Topsøe A/S | Materiał aktywny litowej elektrody dodatniej o wysokiej gęstości nasypowej z usadem, półprodukt i sposób wytwarzania |
| WO2018024186A1 (zh) | 2016-08-02 | 2018-02-08 | 江苏恒瑞医药股份有限公司 | 一种人胰岛素或其类似物的酰化衍生物 |
| PE20210857A1 (es) | 2016-12-16 | 2021-05-18 | Novo Nordisk As | Composiciones farmaceuticas que contienen insulina |
| JOP20190273A1 (ar) | 2017-05-26 | 2019-11-24 | Lilly Co Eli | مركب إنسولين معالج بأسيل |
| CN118754967A (zh) * | 2019-12-30 | 2024-10-11 | 甘李药业股份有限公司 | 胰岛素衍生物 |
| EP4086277A4 (en) * | 2019-12-30 | 2024-02-14 | Gan & Lee Pharmaceuticals Co., Ltd. | Long-acting glp-1 compound |
| US20250340610A1 (en) * | 2022-01-28 | 2025-11-06 | Gan & Lee Pharmaceuticals Co., Ltd. | Acylated insulin |
-
2020
- 2020-12-29 CN CN202411113581.XA patent/CN118754967A/zh active Pending
- 2020-12-29 WO PCT/CN2020/141018 patent/WO2021136293A1/zh not_active Ceased
- 2020-12-29 US US17/758,108 patent/US20240025957A1/en active Pending
- 2020-12-29 WO PCT/CN2020/141056 patent/WO2021136302A1/zh not_active Ceased
- 2020-12-29 KR KR1020227026305A patent/KR20220119730A/ko active Pending
- 2020-12-29 US US17/758,101 patent/US20240239862A1/en active Pending
- 2020-12-29 CN CN202410286752.2A patent/CN118598978A/zh active Pending
- 2020-12-29 AU AU2020418205A patent/AU2020418205A1/en active Pending
- 2020-12-29 CA CA3166495A patent/CA3166495A1/en active Pending
- 2020-12-29 CA CA3166494A patent/CA3166494A1/en active Pending
- 2020-12-29 CN CN202411113751.4A patent/CN118772259A/zh active Pending
- 2020-12-29 BR BR112022013150A patent/BR112022013150A2/pt unknown
- 2020-12-29 CN CN202410312576.5A patent/CN118666989A/zh active Pending
- 2020-12-29 CN CN202410288928.8A patent/CN118206632A/zh active Pending
- 2020-12-29 JP JP2022540871A patent/JP2023510219A/ja active Pending
- 2020-12-29 CN CN202410312489.XA patent/CN118480114A/zh active Pending
- 2020-12-29 US US17/758,089 patent/US12576136B2/en active Active
- 2020-12-29 EP EP20908882.2A patent/EP4086278A4/en active Pending
- 2020-12-29 BR BR112022013009A patent/BR112022013009A2/pt unknown
- 2020-12-29 CN CN202410254905.5A patent/CN118420744A/zh active Pending
- 2020-12-29 MX MX2022008130A patent/MX2022008130A/es unknown
- 2020-12-29 CN CN202080091196.3A patent/CN114901682B/zh active Active
- 2020-12-29 CN CN202411112792.1A patent/CN118894922A/zh active Pending
- 2020-12-29 CN CN202080091328.2A patent/CN114901683B/zh active Active
- 2020-12-29 WO PCT/CN2020/141023 patent/WO2021136296A1/zh not_active Ceased
- 2020-12-29 JP JP2022540767A patent/JP2023510206A/ja active Pending
- 2020-12-29 EP EP20910566.7A patent/EP4086279A4/en active Pending
- 2020-12-29 CN CN202410254314.8A patent/CN118420743A/zh active Pending
- 2020-12-29 AU AU2020417892A patent/AU2020417892A1/en active Pending
- 2020-12-29 MX MX2022008174A patent/MX2022008174A/es unknown
- 2020-12-29 EP EP20910739.0A patent/EP4086280A4/en active Pending
- 2020-12-29 KR KR1020227024018A patent/KR20220121833A/ko active Pending
- 2020-12-29 CN CN202080091153.5A patent/CN114901681B/zh active Active
-
2024
- 2024-09-18 US US18/889,097 patent/US20250032589A1/en not_active Abandoned
-
2025
- 2025-02-12 US US19/052,262 patent/US20250228919A1/en not_active Abandoned
- 2025-07-31 JP JP2025128114A patent/JP2025161829A/ja active Pending
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