JP2023510218A5 - - Google Patents
Info
- Publication number
- JP2023510218A5 JP2023510218A5 JP2022540870A JP2022540870A JP2023510218A5 JP 2023510218 A5 JP2023510218 A5 JP 2023510218A5 JP 2022540870 A JP2022540870 A JP 2022540870A JP 2022540870 A JP2022540870 A JP 2022540870A JP 2023510218 A5 JP2023510218 A5 JP 2023510218A5
- Authority
- JP
- Japan
- Prior art keywords
- human insulin
- γglu
- desb30 human
- eicosanedioyl
- ethoxy
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201911397405.2 | 2019-12-30 | ||
| CN201911397405 | 2019-12-30 | ||
| CN202011053306 | 2020-09-29 | ||
| CN202011053306.5 | 2020-09-29 | ||
| PCT/CN2020/141057 WO2021136303A1 (zh) | 2019-12-30 | 2020-12-29 | 长效glp-1化合物 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2023510218A JP2023510218A (ja) | 2023-03-13 |
| JP2023510218A5 true JP2023510218A5 (cg-RX-API-DMAC10.html) | 2025-10-27 |
| JP7885124B2 JP7885124B2 (ja) | 2026-07-06 |
Family
ID=76687327
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022540870A Active JP7885124B2 (ja) | 2019-12-30 | 2020-12-29 | 長時間作用型ｇｌｐ－１化合物 |
Country Status (10)
| Country | Link |
|---|---|
| US (2) | US12703731B2 (cg-RX-API-DMAC10.html) |
| EP (1) | EP4086277A4 (cg-RX-API-DMAC10.html) |
| JP (1) | JP7885124B2 (cg-RX-API-DMAC10.html) |
| KR (1) | KR20220119731A (cg-RX-API-DMAC10.html) |
| CN (5) | CN119529057A (cg-RX-API-DMAC10.html) |
| AU (1) | AU2020418207A1 (cg-RX-API-DMAC10.html) |
| BR (1) | BR112022013042A2 (cg-RX-API-DMAC10.html) |
| CA (1) | CA3166496A1 (cg-RX-API-DMAC10.html) |
| MX (1) | MX2022008139A (cg-RX-API-DMAC10.html) |
| WO (1) | WO2021136303A1 (cg-RX-API-DMAC10.html) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BR112022013009A2 (pt) * | 2019-12-30 | 2022-09-06 | Gan & Lee Pharmaceuticals Co Ltd | Derivados de insulina, composição farmacêutica, uso do derivado da insulina e métodos para tratar ou prevenir diabetes, para aumentar a capacidade de um derivado de insulina e para aumentar a potência de um derivado de insulina |
| AU2020418207A1 (en) * | 2019-12-30 | 2022-08-25 | Gan & Lee Pharmaceuticals Co., Ltd. | Long-acting GLP-1 compound |
| KR20240118914A (ko) | 2021-01-20 | 2024-08-05 | 바이킹 테라퓨틱스 인코포레이티드 | 대사 및 간 질환 치료를 위한 조성물 및 방법 |
| CN117561072A (zh) * | 2021-06-25 | 2024-02-13 | 甘李药业股份有限公司 | 含glp-1化合物的药物组合物 |
| CA3231953A1 (en) | 2021-09-15 | 2023-03-23 | Brian Lian | Compositions and methods for the treatment of metabolic and liver disorders |
| CN118103391A (zh) * | 2021-11-12 | 2024-05-28 | 福建盛迪医药有限公司 | Glp-1受体和gip受体双重激动剂的药物组合物及其用途 |
| WO2023143458A1 (zh) * | 2022-01-28 | 2023-08-03 | 甘李药业股份有限公司 | 酰化胰岛素 |
| CN120731085A (zh) * | 2023-03-02 | 2025-09-30 | 甘李药业股份有限公司 | 一种glp-1化合物的医药用途 |
| JP2026517987A (ja) * | 2023-05-24 | 2026-06-02 | ザ ユナイテッド バイオテクノロジー（ヘンチン）シーオー．，エルティーディー． | インスリン誘導体およびその使用 |
| EP4741420A1 (en) * | 2023-06-30 | 2026-05-13 | Huonslab Co., Ltd. | Pharmaceutical composition for preventing or treating obesity comprising glp analogue as active ingredient |
| AU2024358560A1 (en) | 2023-10-09 | 2026-05-14 | Gan & Lee Pharmaceuticals Co., Ltd. | Glp -1 peptide composition and use thereof |
| IL328182A (en) | 2023-11-06 | 2026-07-01 | Gan & Lee Pharmaceuticals Co Ltd | GLP-1 receptor agonist for weight loss |
| WO2025098415A1 (zh) | 2023-11-06 | 2025-05-15 | 甘李药业股份有限公司 | 用于降糖的glp-1化合物 |
| WO2025098457A1 (zh) * | 2023-11-07 | 2025-05-15 | 甘李药业股份有限公司 | 用于降糖的酰化胰岛素 |
| CN122555570A (zh) * | 2023-11-08 | 2026-08-11 | 甘李药业股份有限公司 | 包含胰岛素衍生物的药物组合物的治疗用途 |
| WO2025124473A1 (zh) * | 2023-12-12 | 2025-06-19 | 江苏恒瑞医药股份有限公司 | Glp-1类似物治疗代谢疾病的方法及医药用途 |
| WO2026109062A1 (zh) * | 2024-11-25 | 2026-05-28 | 甘李药业股份有限公司 | 含酰化胰岛素的药物组合物 |
Family Cites Families (38)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NZ199391A (en) | 1981-01-02 | 1985-12-13 | Genentech Inc | Chimeric polypeptides comprising a proinsulin sequence,and preparation by recombinant dna technique;production of human insulin |
| DK58285D0 (da) | 1984-05-30 | 1985-02-08 | Novo Industri As | Peptider samt fremstilling og anvendelse deraf |
| PH25772A (en) | 1985-08-30 | 1991-10-18 | Novo Industri As | Insulin analogues, process for their preparation |
| DK336188D0 (da) | 1988-06-20 | 1988-06-20 | Nordisk Gentofte | Propeptider |
| HUT56857A (en) | 1988-12-23 | 1991-10-28 | Novo Nordisk As | Human insulin analogues |
| IL93282A (en) | 1989-02-09 | 1995-08-31 | Lilly Co Eli | Insulin analogues |
| NZ273285A (en) | 1993-09-17 | 1997-10-24 | Novo Nordisk As | Insulin derivatives and compositions thereof |
| WO1995016708A1 (en) | 1993-12-17 | 1995-06-22 | Novo Nordisk A/S | Proinsulin-like compounds |
| US6500645B1 (en) | 1994-06-17 | 2002-12-31 | Novo Nordisk A/S | N-terminally extended proteins expressed in yeast |
| KR0150565B1 (ko) | 1995-02-15 | 1998-08-17 | 김정재 | 유전자 조환에 의한 사람 인슐린 전구체의 제조 및 이를 이용한 인슐린의 제조방법 |
| IL118127A0 (en) | 1995-05-05 | 1996-09-12 | Lilly Co Eli | Single chain insulin with high bioactivity |
| DE122009000079I2 (de) | 1996-08-30 | 2011-06-16 | Novo Nordisk As Novo Alle | Glp-1 derivate |
| AU3247799A (en) | 1998-02-27 | 1999-09-15 | Novo Nordisk A/S | Glp-1 derivatives of glp-1 and exendin with protracted profile of action |
| EP1137667B1 (en) | 1998-12-07 | 2004-11-17 | Societe De Conseils De Recherches Et D'applications Scientifiques S.A.S. | Analogues of glp-1 |
| PT1180121E (pt) | 1999-05-17 | 2004-03-31 | Conjuchem Inc | Peptidos insulinotropicos de longa duracao |
| EP1670515A2 (en) | 2003-09-19 | 2006-06-21 | Novo Nordisk A/S | Albumin-binding derivatives of therapeutic peptides |
| ES2542228T3 (es) * | 2004-07-08 | 2015-08-03 | Novo Nordisk A/S | Marcas de prolongación polipeptídica que comprenden un resto de tetrazol |
| TWI362392B (en) | 2005-03-18 | 2012-04-21 | Novo Nordisk As | Acylated glp-1 compounds |
| WO2009022006A1 (en) | 2007-08-15 | 2009-02-19 | Novo Nordisk A/S | Insulins with an acyl moiety comprising repeating units of alkylene glycol containing amino acids |
| AU2008288413B2 (en) | 2007-08-15 | 2013-09-26 | Novo Nordisk A/S | Insulin analogues with an acyl and aklylene glycol moiety |
| US20100292133A1 (en) | 2007-09-05 | 2010-11-18 | Novo Nordisk A/S | Truncated glp-1 derivaties and their therapeutical use |
| US20100261637A1 (en) * | 2007-09-05 | 2010-10-14 | Novo Nordisk A/S | Peptides derivatized with a-b-c-d- and their therapeutical use |
| HUE032284T2 (en) * | 2008-03-18 | 2017-09-28 | Novo Nordisk As | Protease-stabilized, acylated insulin analogues |
| MX377589B (es) | 2010-12-16 | 2025-03-10 | Novo Nordisk As | Composiciones sólidas que comprenden agonista de glp-1 y sal del ácido n-(8-(2-hidroxibenzoil)amino)caprílico. |
| US8788849B2 (en) * | 2011-02-28 | 2014-07-22 | Sandisk Technologies Inc. | Method and apparatus for protecting cached streams |
| KR102072202B1 (ko) | 2012-03-22 | 2020-01-31 | 노보 노르디스크 에이/에스 | Ｇｌｐ-1 펩티드의 조성물 및 그것의 제조 |
| HUE049152T2 (hu) * | 2012-07-01 | 2020-09-28 | Novo Nordisk As | Hosszantartó hatású GLP-1 peptidek alkalmazása |
| RS58039B1 (sr) | 2013-05-02 | 2019-02-28 | Novo Nordisk As | Oralno doziranje glp-1 jedinjenja |
| BR112018002416A2 (pt) * | 2015-08-25 | 2018-09-18 | Novo Nordisk As | derivados de insulina e seus usos médicos |
| WO2017205191A1 (en) * | 2016-05-24 | 2017-11-30 | Merck Sharp & Dohme Corp. | Insulin receptor partial agonists and glp-1 analogues |
| ES2886837T3 (es) * | 2016-12-16 | 2021-12-21 | Novo Nordisk As | Composiciones farmacéuticas que contienen insulina |
| CN109248323B (zh) * | 2017-07-14 | 2023-09-08 | 杭州先为达生物科技有限公司 | 酰化的glp-1衍生物 |
| WO2019200594A1 (zh) | 2018-04-19 | 2019-10-24 | 杭州先为达生物科技有限公司 | 酰化的glp-1衍生物 |
| TWI829687B (zh) | 2018-05-07 | 2024-01-21 | 丹麥商諾佛 儂迪克股份有限公司 | 包含glp-1促效劑與n-(8-(2-羥基苯甲醯基)胺基)辛酸之鹽的固體組成物 |
| AU2020418207A1 (en) * | 2019-12-30 | 2022-08-25 | Gan & Lee Pharmaceuticals Co., Ltd. | Long-acting GLP-1 compound |
| BR112022013009A2 (pt) * | 2019-12-30 | 2022-09-06 | Gan & Lee Pharmaceuticals Co Ltd | Derivados de insulina, composição farmacêutica, uso do derivado da insulina e métodos para tratar ou prevenir diabetes, para aumentar a capacidade de um derivado de insulina e para aumentar a potência de um derivado de insulina |
| US20240316157A1 (en) | 2021-06-25 | 2024-09-26 | Gan & Lee Pharmaceuticals Co., Ltd. | Pharmaceutical composition of pcsk9 inhibitor and glp-1 receptor agonist |
| CN117561072A (zh) | 2021-06-25 | 2024-02-13 | 甘李药业股份有限公司 | 含glp-1化合物的药物组合物 |
-
2020
- 2020-12-29 AU AU2020418207A patent/AU2020418207A1/en active Pending
- 2020-12-29 MX MX2022008139A patent/MX2022008139A/es unknown
- 2020-12-29 CN CN202411172451.3A patent/CN119529057A/zh active Pending
- 2020-12-29 CN CN202080091240.0A patent/CN114901680B/zh active Active
- 2020-12-29 CN CN202411172489.0A patent/CN119060162B/zh active Active
- 2020-12-29 CN CN202411172559.2A patent/CN119060163A/zh active Pending
- 2020-12-29 CN CN202411172407.2A patent/CN119060161A/zh active Pending
- 2020-12-29 BR BR112022013042A patent/BR112022013042A2/pt unknown
- 2020-12-29 US US17/758,113 patent/US12703731B2/en active Active
- 2020-12-29 KR KR1020227026310A patent/KR20220119731A/ko active Pending
- 2020-12-29 WO PCT/CN2020/141057 patent/WO2021136303A1/zh not_active Ceased
- 2020-12-29 JP JP2022540870A patent/JP7885124B2/ja active Active
- 2020-12-29 EP EP20909624.7A patent/EP4086277A4/en active Pending
- 2020-12-29 CA CA3166496A patent/CA3166496A1/en active Pending
-
2024
- 2024-09-12 US US18/883,592 patent/US20250011385A1/en not_active Abandoned
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