JP2023502968A5 - - Google Patents
Info
- Publication number
- JP2023502968A5 JP2023502968A5 JP2022528305A JP2022528305A JP2023502968A5 JP 2023502968 A5 JP2023502968 A5 JP 2023502968A5 JP 2022528305 A JP2022528305 A JP 2022528305A JP 2022528305 A JP2022528305 A JP 2022528305A JP 2023502968 A5 JP2023502968 A5 JP 2023502968A5
- Authority
- JP
- Japan
- Prior art keywords
- amino acid
- seq
- acid sequence
- sequence described
- cdr
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2025104401A JP2025134876A (ja) | 2019-11-15 | 2025-06-20 | アミロイド沈着物を標的化するための修飾免疫グロブリン |
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201962936002P | 2019-11-15 | 2019-11-15 | |
| US62/936,002 | 2019-11-15 | ||
| US202063074912P | 2020-09-04 | 2020-09-04 | |
| US63/074,912 | 2020-09-04 | ||
| PCT/US2020/060596 WO2021097360A1 (en) | 2019-11-15 | 2020-11-13 | Modified immunoglobulins for targeting amyloid deposits |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2025104401A Division JP2025134876A (ja) | 2019-11-15 | 2025-06-20 | アミロイド沈着物を標的化するための修飾免疫グロブリン |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2023502968A JP2023502968A (ja) | 2023-01-26 |
| JP2023502968A5 true JP2023502968A5 (https=) | 2023-11-20 |
| JP7722990B2 JP7722990B2 (ja) | 2025-08-13 |
Family
ID=75912899
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022528305A Active JP7722990B2 (ja) | 2019-11-15 | 2020-11-13 | アミロイド沈着物を標的化するための修飾免疫グロブリン |
| JP2025104401A Pending JP2025134876A (ja) | 2019-11-15 | 2025-06-20 | アミロイド沈着物を標的化するための修飾免疫グロブリン |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2025104401A Pending JP2025134876A (ja) | 2019-11-15 | 2025-06-20 | アミロイド沈着物を標的化するための修飾免疫グロブリン |
Country Status (11)
| Country | Link |
|---|---|
| US (5) | US20220411489A1 (https=) |
| EP (1) | EP4058479A4 (https=) |
| JP (2) | JP7722990B2 (https=) |
| KR (1) | KR20220113950A (https=) |
| CN (1) | CN115298214A (https=) |
| AU (1) | AU2020385183A1 (https=) |
| BR (1) | BR112022009273A2 (https=) |
| CA (1) | CA3158206A1 (https=) |
| IL (1) | IL292903B2 (https=) |
| MX (1) | MX2022005850A (https=) |
| WO (1) | WO2021097360A1 (https=) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN115298214A (zh) | 2019-11-15 | 2022-11-04 | 田纳西大学研究基金会 | 用于靶向淀粉样蛋白沉积物的经修饰的免疫球蛋白 |
| KR20230144525A (ko) * | 2020-12-04 | 2023-10-16 | 유니버시티 오브 테네시 리서치 파운데이션 | 아밀로이드 질환을 진단하기 위한 방법 |
| CA3217756A1 (en) * | 2021-05-05 | 2022-11-10 | Jonathan S. Wall | Peptide-fc fusions for treating amyloid disorders |
| JP2024521082A (ja) | 2021-05-18 | 2024-05-28 | ユニバーシティ オブ テネシー リサーチ ファウンデーション | アミロイド障害を処置するための抗体－ペプチド融合タンパク質 |
| KR20240055101A (ko) * | 2021-09-14 | 2024-04-26 | 시일럼 바이오사이언시즈, 인크. | 다발성 골수종의 치료 방법 |
| US20250019425A1 (en) * | 2021-11-12 | 2025-01-16 | Adrx, Inc. | Transthyretin (ttr) monomer binding antibodies |
| JP2025515741A (ja) * | 2022-05-11 | 2025-05-20 | アレクシオン ファーマシューティカルズ， インコーポレイテッド | 高感度ビオチン化ペプチド結合ｅｌｉｓａアッセイ |
| WO2024050478A1 (en) * | 2022-09-02 | 2024-03-07 | University Of Tennessee Research Foundation | Chimeric antigen receptors for removal of amyloid |
| AU2024339036A1 (en) | 2023-09-07 | 2026-03-12 | University Of Tennessee Research Foundation | Method for diagnosing amyloid diseases |
| WO2025212955A1 (en) | 2024-04-05 | 2025-10-09 | University Of Tennessee Research Foundation | Method for diagnosing amyloid diseases |
| WO2026055521A1 (en) * | 2024-09-06 | 2026-03-12 | University Of Tennessee Research Foundation | Antibody-peptide fusion proteins for treating amyloid disorders |
Family Cites Families (28)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5530101A (en) * | 1988-12-28 | 1996-06-25 | Protein Design Labs, Inc. | Humanized immunoglobulins |
| US5959177A (en) | 1989-10-27 | 1999-09-28 | The Scripps Research Institute | Transgenic plants expressing assembled secretory antibodies |
| US7018809B1 (en) | 1991-09-19 | 2006-03-28 | Genentech, Inc. | Expression of functional antibody fragments |
| WO1995015982A2 (en) * | 1993-12-08 | 1995-06-15 | Genzyme Corporation | Process for generating specific antibodies |
| US5789199A (en) | 1994-11-03 | 1998-08-04 | Genentech, Inc. | Process for bacterial production of polypeptides |
| US5840523A (en) | 1995-03-01 | 1998-11-24 | Genetech, Inc. | Methods and compositions for secretion of heterologous polypeptides |
| US6040498A (en) | 1998-08-11 | 2000-03-21 | North Caroline State University | Genetically engineered duckweed |
| DE69942274D1 (de) * | 1998-05-21 | 2010-06-02 | Univ Tennessee Res Foundation | Methoden zur amyloidentfernung mit anti-amyloid-antikörper |
| US20030147882A1 (en) | 1998-05-21 | 2003-08-07 | Alan Solomon | Methods for amyloid removal using anti-amyloid antibodies |
| US7312318B2 (en) * | 2002-03-01 | 2007-12-25 | Immunomedics, Inc. | Internalizing anti-CD74 antibodies and methods of use |
| US7125978B1 (en) | 1999-10-04 | 2006-10-24 | Medicago Inc. | Promoter for regulating expression of foreign genes |
| ES2248127T3 (es) | 1999-10-04 | 2006-03-16 | Medicago Inc. | Metodo para regular la transcripcion de genes foraneos en presencia de nigtrogeno. |
| US20070021345A1 (en) | 2003-06-30 | 2007-01-25 | Ehud Gazit | Peptides antibodies directed thereagainst and methods using same for diagnosing and treating amyloid-associated diseases |
| ATE439443T1 (de) | 2005-06-17 | 2009-08-15 | Ca Nat Research Council | NEUES Aß-BINDUNGSPROTEIN UND DESSEN PEPTIDDERIVATE SOWIE VERWENDUNGEN DAVON |
| EP2125893A2 (en) * | 2007-01-23 | 2009-12-02 | Xencor, Inc. | Optimized cd40 antibodies and methods of using the same |
| DK2237803T3 (en) * | 2007-12-28 | 2015-10-05 | Prothena Biosciences Ltd | Treatment and prophylaxis of amyloidosis |
| US10076570B2 (en) | 2009-08-07 | 2018-09-18 | Transgene S.A. | Composition for treating HBV infection |
| WO2011119608A1 (en) | 2010-03-26 | 2011-09-29 | University Of Tennessee Research Foundation | Peptides that specifically target amyloid deposits |
| US20140079691A1 (en) | 2012-09-20 | 2014-03-20 | Anaptysbio, Inc. | Thermostable antibody framework regions |
| US9683017B2 (en) | 2014-07-17 | 2017-06-20 | University Tennessee Research Foundation | Inhibitory peptides of viral infection |
| US10213506B2 (en) | 2014-08-26 | 2019-02-26 | University Of Tennessee Research Foundation | Targeting immunotherapy for amyloidosis |
| WO2018138709A1 (en) | 2017-01-30 | 2018-08-02 | National Research Council Of Canada | Blood-brain barrier transmigrating compounds and uses thereof |
| US11530257B2 (en) * | 2017-06-29 | 2022-12-20 | The Trustees Of Columbia University In The City Of New York | Chimeric antibodies for treatment of amyloid deposition diseases |
| US11382974B2 (en) | 2017-08-01 | 2022-07-12 | The Trustees Of Columbia University In The City Of New York | Methods and compositions for treatment of amyloid deposition diseases |
| WO2019241216A1 (en) | 2018-06-14 | 2019-12-19 | Bioatla, Llc | Multi-specific antibody constructs |
| US12018069B2 (en) | 2018-06-28 | 2024-06-25 | The Trustees Of Columbia University In The City Of New York | Methods and compositions for imaging amyloid deposits |
| CN115298214A (zh) | 2019-11-15 | 2022-11-04 | 田纳西大学研究基金会 | 用于靶向淀粉样蛋白沉积物的经修饰的免疫球蛋白 |
| JP2024521082A (ja) | 2021-05-18 | 2024-05-28 | ユニバーシティ オブ テネシー リサーチ ファウンデーション | アミロイド障害を処置するための抗体－ペプチド融合タンパク質 |
-
2020
- 2020-11-13 CN CN202080092570.1A patent/CN115298214A/zh active Pending
- 2020-11-13 EP EP20887541.9A patent/EP4058479A4/en active Pending
- 2020-11-13 IL IL292903A patent/IL292903B2/en unknown
- 2020-11-13 AU AU2020385183A patent/AU2020385183A1/en active Pending
- 2020-11-13 JP JP2022528305A patent/JP7722990B2/ja active Active
- 2020-11-13 MX MX2022005850A patent/MX2022005850A/es unknown
- 2020-11-13 BR BR112022009273A patent/BR112022009273A2/pt unknown
- 2020-11-13 CA CA3158206A patent/CA3158206A1/en active Pending
- 2020-11-13 US US17/776,827 patent/US20220411489A1/en not_active Abandoned
- 2020-11-13 KR KR1020227019864A patent/KR20220113950A/ko active Pending
- 2020-11-13 WO PCT/US2020/060596 patent/WO2021097360A1/en not_active Ceased
-
2023
- 2023-03-09 US US18/181,489 patent/US12030934B2/en active Active
-
2024
- 2024-05-09 US US18/660,156 patent/US12157765B2/en active Active
- 2024-05-09 US US18/660,162 patent/US12264195B2/en active Active
-
2025
- 2025-02-12 US US19/052,001 patent/US20250368729A1/en active Pending
- 2025-06-20 JP JP2025104401A patent/JP2025134876A/ja active Pending
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2023502968A5 (https=) | ||
| JP7019198B2 (ja) | 補体関連疾患の予防及び治療のためのｃ５抗体及び方法 | |
| JP2025134876A5 (https=) | ||
| CA2762594C (en) | Use of an anti-tau ps422 antibody for the treatment of brain diseases | |
| US12264195B2 (en) | Modified immunoglobulins for targeting amyloid deposits | |
| JP2021503455A5 (https=) | ||
| JP2012515746A (ja) | 抗ｃｄ１６０モノクローナル抗体及びその使用 | |
| NZ717476A (en) | Anti-garp protein and uses thereof | |
| TW200840821A (en) | Methods of purifying anti A beta antibodies | |
| JP2005528914A5 (https=) | ||
| JP7618240B2 (ja) | 脳神経系疾患の予防または治療用組成物 | |
| AU2022273136A9 (en) | Binding molecule against dll3 and use thereof | |
| IL297143A (en) | Anti-cd98 antibodies and their uses | |
| TW201134489A (en) | Basigin binding proteins | |
| CN115109156A (zh) | 一种靶向bcma的纳米抗体及其应用 | |
| US20190330318A1 (en) | Anti-hspa5 (grp78) antibodies and uses thereof | |
| JP2022521305A (ja) | 抗ｐｄ－ｌ１抗体及びその使用 | |
| KR20260030123A (ko) | 혈액 뇌 장벽을 통과하여 그라눌린을 전달하기 위한 화합물 | |
| AU2020267874A1 (en) | Anti-Sema3A antibodies and their uses for treating eye or ocular diseases | |
| JP2023533533A5 (https=) | ||
| WO2022051223A1 (en) | Use of sars-cov-2 receptor binding motif (rbm)-reactive monoclonal antibodies to treat covid-19 | |
| US20240059764A1 (en) | ANTIGEN-BINDING PROTEIN TARGETING STAPHYLOCOCCUS AUREUS a-HEMOLYSIS AND APPLICATION THEREOF | |
| WO2025086564A1 (zh) | 抗人vsig4的抗体及其医药用途 | |
| US20240376222A1 (en) | Tfr antigen binding proteins and uses thereof | |
| JP2024535851A5 (https=) |