JP2023501722A5 - - Google Patents

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Publication number
JP2023501722A5
JP2023501722A5 JP2022528263A JP2022528263A JP2023501722A5 JP 2023501722 A5 JP2023501722 A5 JP 2023501722A5 JP 2022528263 A JP2022528263 A JP 2022528263A JP 2022528263 A JP2022528263 A JP 2022528263A JP 2023501722 A5 JP2023501722 A5 JP 2023501722A5
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JP
Japan
Prior art keywords
subfamily
tcrβ
subject
cancer
cell
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Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2022528263A
Other languages
English (en)
Japanese (ja)
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JP2023501722A (ja
JP7590430B2 (ja
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Priority claimed from PCT/US2020/060557 external-priority patent/WO2021097325A1/en
Publication of JP2023501722A publication Critical patent/JP2023501722A/ja
Publication of JP2023501722A5 publication Critical patent/JP2023501722A5/ja
Priority to JP2024198993A priority Critical patent/JP2025024094A/ja
Application granted granted Critical
Publication of JP7590430B2 publication Critical patent/JP7590430B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

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JP2022528263A 2019-11-14 2020-11-13 抗tcr抗体分子およびその使用 Active JP7590430B2 (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2024198993A JP2025024094A (ja) 2019-11-14 2024-11-14 抗tcr抗体分子およびその使用

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201962935172P 2019-11-14 2019-11-14
US62/935,172 2019-11-14
US202062956969P 2020-01-03 2020-01-03
US62/956,969 2020-01-03
PCT/US2020/060557 WO2021097325A1 (en) 2019-11-14 2020-11-13 Anti-tcr antibody molecules and uses thereof

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2024198993A Division JP2025024094A (ja) 2019-11-14 2024-11-14 抗tcr抗体分子およびその使用

Publications (3)

Publication Number Publication Date
JP2023501722A JP2023501722A (ja) 2023-01-18
JP2023501722A5 true JP2023501722A5 (enExample) 2024-05-13
JP7590430B2 JP7590430B2 (ja) 2024-11-26

Family

ID=75912403

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2022528263A Active JP7590430B2 (ja) 2019-11-14 2020-11-13 抗tcr抗体分子およびその使用
JP2024198993A Pending JP2025024094A (ja) 2019-11-14 2024-11-14 抗tcr抗体分子およびその使用

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2024198993A Pending JP2025024094A (ja) 2019-11-14 2024-11-14 抗tcr抗体分子およびその使用

Country Status (8)

Country Link
US (1) US20230048244A1 (enExample)
EP (1) EP4058483A4 (enExample)
JP (2) JP7590430B2 (enExample)
CN (1) CN115003698A (enExample)
AU (2) AU2020384369B2 (enExample)
CA (1) CA3160997A1 (enExample)
GB (1) GB2607452B (enExample)
WO (1) WO2021097325A1 (enExample)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US12247060B2 (en) 2018-01-09 2025-03-11 Marengo Therapeutics, Inc. Calreticulin binding constructs and engineered T cells for the treatment of diseases
EP3765517A1 (en) 2018-03-14 2021-01-20 Elstar Therapeutics, Inc. Multifunctional molecules that bind to calreticulin and uses thereof
CA3105448A1 (en) 2018-07-03 2020-01-09 Elstar Therapeutics, Inc. Anti-tcr antibody molecules and uses thereof
GB2599228B (en) 2019-02-21 2024-02-07 Marengo Therapeutics Inc Multifunctional molecules that bind to T cell related cancer cells and uses thereof
CN119039441A (zh) 2019-02-21 2024-11-29 马伦戈治疗公司 与nkp30结合的抗体分子及其用途
AU2020416273A1 (en) 2020-01-03 2022-07-28 Marengo Therapeutics, Inc. Anti-TCR antibody molecules and uses thereof
EP4413044A4 (en) * 2021-10-07 2025-10-22 Nat Res Council Canada ANTI-CD3 MONOCLONAL ANTIBODIES AND THERAPEUTIC CONSTRUCTS
EP4426321A4 (en) * 2021-11-05 2025-12-10 Marengo Therapeutics Inc IMMUNE CELL POPULATIONS AND THEIR USES
KR20250143365A (ko) * 2022-10-12 2025-10-01 마렝고 테라퓨틱스, 인크. Tcr에 결합하는 다기능성 분자 및 이의 용도
AU2024240821A1 (en) 2023-03-23 2025-11-06 Bodhi Bio Llc Compositions and methods for antigen-specific therapy
WO2025051339A1 (en) * 2023-09-05 2025-03-13 Tiber Biotech Srl SINGLE-CHAIN VARIABLE FRAGMENT AND MOLECULES DERIVING THEREFROM THAT BIND FRAGMENT TRVB5-1 OF THE β CHAIN OF HUMAN T-CELL RECEPTOR
WO2025245071A1 (en) * 2024-05-21 2025-11-27 Marengo Therapeutics, Inc. Multifunctional molecules binding to tcr and uses thereof

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5766947A (en) * 1988-12-14 1998-06-16 Astra Ab Monoclonal antibodies reactive with an epitope of a Vβ3.1 variable region of a T cell receptor
US5776459A (en) * 1989-07-19 1998-07-07 Connetics Corporation TCR V beta 5 peptides
WO2000006733A2 (en) * 1998-07-29 2000-02-10 Heska Corporation T cell receptor proteins, nucleic acid molecules, and uses thereof
JP5184732B2 (ja) * 2000-06-19 2013-04-17 ベス イスラエル デアコネス メディカル センター T細胞亜集団に特異的なモノクローナル抗体およびポリクローナル抗体の組成物および使用方法
GB0328363D0 (en) * 2003-12-06 2004-01-14 Imp College Innovations Ltd Therapeutically useful molecules
US9018006B2 (en) * 2010-07-23 2015-04-28 The University Of Toledo Stable Tregs and related materials and methods
DK2623604T3 (da) * 2012-02-02 2015-06-01 Baylor College Medicine Adenovirusbaseret biologisk afgivelses- og ekspressionssystem til anvendelse ved behandling af osteoartrose
MX384246B (es) * 2013-10-30 2025-03-14 Genzyme Corp POLIPÉPTIDO DE UNIÓN A TCR ALFA BETA PARA USARSE EN LA DISMINUCIÓN DE LINFOCITOS TAß.
JP2018517712A (ja) * 2015-06-01 2018-07-05 メディジーン イミュノテラピーズ ゲーエムベーハー T細胞受容体特異的抗体
CA3105448A1 (en) * 2018-07-03 2020-01-09 Elstar Therapeutics, Inc. Anti-tcr antibody molecules and uses thereof
GB2595980B (en) * 2019-01-04 2023-06-14 Marengo Therapeutics Inc Anti-TCR antibody molecules and uses thereof
EP3927431A1 (en) * 2019-02-21 2021-12-29 Marengo Therapeutics, Inc. Anti-tcr antibody molecules and uses thereof
AU2020416273A1 (en) * 2020-01-03 2022-07-28 Marengo Therapeutics, Inc. Anti-TCR antibody molecules and uses thereof
EP4426321A4 (en) * 2021-11-05 2025-12-10 Marengo Therapeutics Inc IMMUNE CELL POPULATIONS AND THEIR USES

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