JP2023168298A5 - - Google Patents
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- Publication number
- JP2023168298A5 JP2023168298A5 JP2023078608A JP2023078608A JP2023168298A5 JP 2023168298 A5 JP2023168298 A5 JP 2023168298A5 JP 2023078608 A JP2023078608 A JP 2023078608A JP 2023078608 A JP2023078608 A JP 2023078608A JP 2023168298 A5 JP2023168298 A5 JP 2023168298A5
- Authority
- JP
- Japan
- Prior art keywords
- cancer
- pharma
- compound
- acceptable salt
- group
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 150000001875 compounds Chemical class 0.000 claims 49
- 150000003839 salts Chemical class 0.000 claims 26
- 206010028980 Neoplasm Diseases 0.000 claims 18
- 201000011510 cancer Diseases 0.000 claims 18
- 229940124597 therapeutic agent Drugs 0.000 claims 14
- 239000003814 drug Substances 0.000 claims 13
- 208000002154 non-small cell lung carcinoma Diseases 0.000 claims 6
- 208000029729 tumor suppressor gene on chromosome 11 Diseases 0.000 claims 6
- 206010039491 Sarcoma Diseases 0.000 claims 5
- 208000021712 Soft tissue sarcoma Diseases 0.000 claims 5
- 206010005003 Bladder cancer Diseases 0.000 claims 4
- 206010006187 Breast cancer Diseases 0.000 claims 4
- 208000026310 Breast neoplasm Diseases 0.000 claims 4
- 206010009944 Colon cancer Diseases 0.000 claims 4
- 206010014733 Endometrial cancer Diseases 0.000 claims 4
- 206010014759 Endometrial neoplasm Diseases 0.000 claims 4
- 208000032612 Glial tumor Diseases 0.000 claims 4
- 206010018338 Glioma Diseases 0.000 claims 4
- 208000032271 Malignant tumor of penis Diseases 0.000 claims 4
- 208000002471 Penile Neoplasms Diseases 0.000 claims 4
- 206010034299 Penile cancer Diseases 0.000 claims 4
- 208000007097 Urinary Bladder Neoplasms Diseases 0.000 claims 4
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 4
- 208000035475 disorder Diseases 0.000 claims 4
- 201000001441 melanoma Diseases 0.000 claims 4
- 201000008261 skin carcinoma Diseases 0.000 claims 4
- 201000005112 urinary bladder cancer Diseases 0.000 claims 4
- 208000001333 Colorectal Neoplasms Diseases 0.000 claims 3
- 238000011282 treatment Methods 0.000 claims 3
- 206010073360 Appendix cancer Diseases 0.000 claims 2
- 206010005949 Bone cancer Diseases 0.000 claims 2
- 208000018084 Bone neoplasm Diseases 0.000 claims 2
- 206010008342 Cervix carcinoma Diseases 0.000 claims 2
- 208000000461 Esophageal Neoplasms Diseases 0.000 claims 2
- 206010051066 Gastrointestinal stromal tumour Diseases 0.000 claims 2
- 208000021309 Germ cell tumor Diseases 0.000 claims 2
- 206010073073 Hepatobiliary cancer Diseases 0.000 claims 2
- 101000702545 Homo sapiens Transcription activator BRG1 Proteins 0.000 claims 2
- 208000034176 Neoplasms, Germ Cell and Embryonal Diseases 0.000 claims 2
- 208000015914 Non-Hodgkin lymphomas Diseases 0.000 claims 2
- 206010030155 Oesophageal carcinoma Diseases 0.000 claims 2
- 206010033128 Ovarian cancer Diseases 0.000 claims 2
- 206010061535 Ovarian neoplasm Diseases 0.000 claims 2
- 206010061902 Pancreatic neoplasm Diseases 0.000 claims 2
- 206010060862 Prostate cancer Diseases 0.000 claims 2
- 208000000236 Prostatic Neoplasms Diseases 0.000 claims 2
- 208000006265 Renal cell carcinoma Diseases 0.000 claims 2
- 208000004337 Salivary Gland Neoplasms Diseases 0.000 claims 2
- 206010061934 Salivary gland cancer Diseases 0.000 claims 2
- 206010041067 Small cell lung cancer Diseases 0.000 claims 2
- 208000005718 Stomach Neoplasms Diseases 0.000 claims 2
- 208000037432 Thymic tumor Diseases 0.000 claims 2
- 208000000728 Thymus Neoplasms Diseases 0.000 claims 2
- 208000024770 Thyroid neoplasm Diseases 0.000 claims 2
- 102100031027 Transcription activator BRG1 Human genes 0.000 claims 2
- 208000006105 Uterine Cervical Neoplasms Diseases 0.000 claims 2
- 238000011319 anticancer therapy Methods 0.000 claims 2
- 208000021780 appendiceal neoplasm Diseases 0.000 claims 2
- 201000007455 central nervous system cancer Diseases 0.000 claims 2
- 201000010881 cervical cancer Diseases 0.000 claims 2
- 208000014616 embryonal neoplasm Diseases 0.000 claims 2
- 201000004101 esophageal cancer Diseases 0.000 claims 2
- 206010017758 gastric cancer Diseases 0.000 claims 2
- 201000007028 gastrointestinal neuroendocrine tumor Diseases 0.000 claims 2
- 201000011243 gastrointestinal stromal tumor Diseases 0.000 claims 2
- 201000010536 head and neck cancer Diseases 0.000 claims 2
- 208000014829 head and neck neoplasm Diseases 0.000 claims 2
- 230000004777 loss-of-function mutation Effects 0.000 claims 2
- 208000015486 malignant pancreatic neoplasm Diseases 0.000 claims 2
- 230000001394 metastastic effect Effects 0.000 claims 2
- 206010061289 metastatic neoplasm Diseases 0.000 claims 2
- 201000002528 pancreatic cancer Diseases 0.000 claims 2
- 208000008443 pancreatic carcinoma Diseases 0.000 claims 2
- 208000000587 small cell lung carcinoma Diseases 0.000 claims 2
- 201000002314 small intestine cancer Diseases 0.000 claims 2
- 201000011549 stomach cancer Diseases 0.000 claims 2
- 201000009377 thymus cancer Diseases 0.000 claims 2
- 201000002510 thyroid cancer Diseases 0.000 claims 2
- 208000037965 uterine sarcoma Diseases 0.000 claims 2
- 208000036142 Viral infection Diseases 0.000 claims 1
- 208000020990 adrenal cortex carcinoma Diseases 0.000 claims 1
- 230000001919 adrenal effect Effects 0.000 claims 1
- 208000007128 adrenocortical carcinoma Diseases 0.000 claims 1
- 239000012830 cancer therapeutic Substances 0.000 claims 1
- 208000029742 colonic neoplasm Diseases 0.000 claims 1
- 230000001054 cortical effect Effects 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 claims 1
- 239000008194 pharmaceutical composition Substances 0.000 claims 1
- 239000000546 pharmaceutical excipient Substances 0.000 claims 1
- 230000009385 viral infection Effects 0.000 claims 1
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2024122975A JP2024156779A (ja) | 2022-05-11 | 2024-07-30 | 化合物及びその使用 |
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202263340927P | 2022-05-11 | 2022-05-11 | |
| US63/340,927 | 2022-05-11 |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024122975A Division JP2024156779A (ja) | 2022-05-11 | 2024-07-30 | 化合物及びその使用 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2023168298A JP2023168298A (ja) | 2023-11-24 |
| JP2023168298A5 true JP2023168298A5 (https=) | 2024-06-06 |
| JP7531656B2 JP7531656B2 (ja) | 2024-08-09 |
Family
ID=86732694
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023078608A Active JP7531656B2 (ja) | 2022-05-11 | 2023-05-11 | 化合物及びその使用 |
| JP2024122975A Pending JP2024156779A (ja) | 2022-05-11 | 2024-07-30 | 化合物及びその使用 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024122975A Pending JP2024156779A (ja) | 2022-05-11 | 2024-07-30 | 化合物及びその使用 |
Country Status (17)
| Country | Link |
|---|---|
| US (2) | US12139487B2 (https=) |
| EP (1) | EP4522280A1 (https=) |
| JP (2) | JP7531656B2 (https=) |
| KR (1) | KR20250024923A (https=) |
| CN (1) | CN119677738A (https=) |
| AR (1) | AR129299A1 (https=) |
| AU (1) | AU2023270055A1 (https=) |
| CA (1) | CA3252955A1 (https=) |
| CL (1) | CL2024003450A1 (https=) |
| CO (1) | CO2024015229A2 (https=) |
| DO (1) | DOP2024000231A (https=) |
| IL (1) | IL316531A (https=) |
| JO (1) | JOP20240250A1 (https=) |
| MX (1) | MX2024013838A (https=) |
| PE (1) | PE20250261A1 (https=) |
| TW (2) | TW202506693A (https=) |
| WO (1) | WO2023220219A1 (https=) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP7675182B2 (ja) * | 2020-11-10 | 2025-05-12 | フォグホーン セラピューティクス インコーポレイテッド | 化合物及びその使用 |
| CN121443603A (zh) * | 2023-07-05 | 2026-01-30 | 詹森药业有限公司 | 能够用于治疗smarca4缺失型癌症的作为smarca2抑制剂的1,6-萘啶化合物 |
| WO2025099307A1 (en) * | 2023-11-10 | 2025-05-15 | Galapagos Nv | Compounds and pharmaceutical compositions thereof for the treatment of diseases |
| WO2025193614A1 (en) * | 2024-03-11 | 2025-09-18 | Enanta Pharmaceuticals, Inc. | Fused heterobicyclic antiviral agents |
| WO2025209520A1 (zh) * | 2024-04-03 | 2025-10-09 | 深圳众格生物科技有限公司 | 一种化合物、包含其的药物组合物及其用途 |
| WO2025237242A1 (zh) * | 2024-05-14 | 2025-11-20 | 上海和誉生物医药科技有限公司 | 一种smarca2抑制剂及其应用 |
| CN118930561B (zh) * | 2024-07-23 | 2025-04-08 | 上海信诺维生物医药有限公司 | 一种稠环化合物 |
| CN118930537B (zh) * | 2024-07-23 | 2025-05-13 | 上海信诺维生物医药有限公司 | 一种抑制brm的化合物 |
| CN118908980B (zh) * | 2024-07-23 | 2025-04-08 | 上海信诺维生物医药有限公司 | 一种多环化合物 |
| WO2026046365A1 (zh) * | 2024-08-30 | 2026-03-05 | 上海齐鲁制药研究中心有限公司 | Smarca2抑制剂及其制备方法和用途 |
| WO2026057002A1 (zh) * | 2024-09-12 | 2026-03-19 | 江苏恒瑞医药股份有限公司 | 一种烯炔类化合物及其应用 |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101511840A (zh) | 2006-04-26 | 2009-08-19 | 吉宁特有限公司 | 磷酸肌醇3-激酶抑制剂化合物及其使用方法 |
| US9050345B2 (en) | 2013-03-11 | 2015-06-09 | Bristol-Myers Squibb Company | Pyrrolotriazines as potassium ion channel inhibitors |
| US9663502B2 (en) | 2013-12-20 | 2017-05-30 | Lycera Corporation | 2-Acylamidomethyl and sulfonylamidomethyl benzoxazine carbamates for inhibition of RORgamma activity and the treatment of disease |
| RU2743074C2 (ru) | 2014-08-01 | 2021-02-15 | Нуэволюшон А/С | Соединения, активные по отношению к бромодоменам |
| CN115297861B (zh) * | 2020-01-29 | 2024-07-12 | 福宏治疗公司 | 化合物及其用途 |
| US20230121497A1 (en) * | 2020-01-29 | 2023-04-20 | Foghorn Therapeutics Inc. | Compounds and uses thereof |
| CA3167275A1 (en) * | 2020-01-29 | 2021-08-05 | Foghorn Therapeutics Inc. | Compounds and uses thereof |
| US20230149414A1 (en) * | 2020-01-29 | 2023-05-18 | Foghorn Therapeutics Inc. | Compounds and uses thereof |
| US12383555B2 (en) | 2020-05-20 | 2025-08-12 | Foghorn Therapeutics Inc. | Methods of treating cancers |
| JP7675182B2 (ja) | 2020-11-10 | 2025-05-12 | フォグホーン セラピューティクス インコーポレイテッド | 化合物及びその使用 |
-
2023
- 2023-05-11 AR ARP230101168A patent/AR129299A1/es unknown
- 2023-05-11 TW TW113141340A patent/TW202506693A/zh unknown
- 2023-05-11 US US18/315,526 patent/US12139487B2/en active Active
- 2023-05-11 TW TW112117604A patent/TWI864749B/zh active
- 2023-05-11 CN CN202380053231.6A patent/CN119677738A/zh active Pending
- 2023-05-11 CA CA3252955A patent/CA3252955A1/en active Pending
- 2023-05-11 PE PE2024002469A patent/PE20250261A1/es unknown
- 2023-05-11 EP EP23729898.9A patent/EP4522280A1/en active Pending
- 2023-05-11 IL IL316531A patent/IL316531A/en unknown
- 2023-05-11 JP JP2023078608A patent/JP7531656B2/ja active Active
- 2023-05-11 AU AU2023270055A patent/AU2023270055A1/en active Pending
- 2023-05-11 KR KR1020247041093A patent/KR20250024923A/ko active Pending
- 2023-05-11 WO PCT/US2023/021793 patent/WO2023220219A1/en not_active Ceased
-
2024
- 2024-07-30 JP JP2024122975A patent/JP2024156779A/ja active Pending
- 2024-10-25 US US18/926,578 patent/US20250066354A1/en active Pending
- 2024-11-07 JO JOJO/P/2024/0250A patent/JOP20240250A1/ar unknown
- 2024-11-07 CO CONC2024/0015229A patent/CO2024015229A2/es unknown
- 2024-11-08 MX MX2024013838A patent/MX2024013838A/es unknown
- 2024-11-11 DO DO2024000231A patent/DOP2024000231A/es unknown
- 2024-11-11 CL CL2024003450A patent/CL2024003450A1/es unknown
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