JP2023153423A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2023153423A5 JP2023153423A5 JP2023138084A JP2023138084A JP2023153423A5 JP 2023153423 A5 JP2023153423 A5 JP 2023153423A5 JP 2023138084 A JP2023138084 A JP 2023138084A JP 2023138084 A JP2023138084 A JP 2023138084A JP 2023153423 A5 JP2023153423 A5 JP 2023153423A5
- Authority
- JP
- Japan
- Prior art keywords
- hsv
- composition
- infection
- seq
- glycoprotein
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2025069088A JP2025108645A (ja) | 2017-08-17 | 2025-04-18 | 単純ヘルペスウイルス糖タンパク質をコードする修飾ｍＲＮＡワクチン及びその使用 |
Applications Claiming Priority (6)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201762546648P | 2017-08-17 | 2017-08-17 | |
| US62/546,648 | 2017-08-17 | ||
| US201862701019P | 2018-07-20 | 2018-07-20 | |
| US62/701,019 | 2018-07-20 | ||
| JP2020509054A JP7386535B2 (ja) | 2017-08-17 | 2018-08-17 | 単純ヘルペスウイルス糖タンパク質をコードする修飾ｍＲＮＡワクチン及びその使用 |
| PCT/IB2018/056210 WO2019035066A1 (en) | 2017-08-17 | 2018-08-17 | MODIFIED MHRNA VACCINES ENCODING HERPES SIMPLEX VIRUS GLYCOPROTEINS AND USES THEREOF |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020509054A Division JP7386535B2 (ja) | 2017-08-17 | 2018-08-17 | 単純ヘルペスウイルス糖タンパク質をコードする修飾ｍＲＮＡワクチン及びその使用 |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2025069088A Division JP2025108645A (ja) | 2017-08-17 | 2025-04-18 | 単純ヘルペスウイルス糖タンパク質をコードする修飾ｍＲＮＡワクチン及びその使用 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2023153423A JP2023153423A (ja) | 2023-10-17 |
| JP2023153423A5 true JP2023153423A5 (https=) | 2025-03-12 |
| JP7674760B2 JP7674760B2 (ja) | 2025-05-12 |
Family
ID=65362983
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020509054A Active JP7386535B2 (ja) | 2017-08-17 | 2018-08-17 | 単純ヘルペスウイルス糖タンパク質をコードする修飾ｍＲＮＡワクチン及びその使用 |
| JP2023138084A Active JP7674760B2 (ja) | 2017-08-17 | 2023-08-28 | 単純ヘルペスウイルス糖タンパク質をコードする修飾ｍＲＮＡワクチン及びその使用 |
| JP2025069088A Pending JP2025108645A (ja) | 2017-08-17 | 2025-04-18 | 単純ヘルペスウイルス糖タンパク質をコードする修飾ｍＲＮＡワクチン及びその使用 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020509054A Active JP7386535B2 (ja) | 2017-08-17 | 2018-08-17 | 単純ヘルペスウイルス糖タンパク質をコードする修飾ｍＲＮＡワクチン及びその使用 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2025069088A Pending JP2025108645A (ja) | 2017-08-17 | 2025-04-18 | 単純ヘルペスウイルス糖タンパク質をコードする修飾ｍＲＮＡワクチン及びその使用 |
Country Status (7)
| Country | Link |
|---|---|
| US (3) | US11141478B2 (https=) |
| EP (2) | EP4242223A3 (https=) |
| JP (3) | JP7386535B2 (https=) |
| CN (2) | CN111246854A (https=) |
| AU (2) | AU2018316811B2 (https=) |
| CA (1) | CA3073161A1 (https=) |
| WO (1) | WO2019035066A1 (https=) |
Families Citing this family (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MA49463A (fr) * | 2017-04-26 | 2021-05-05 | Modernatx Inc | Vaccin contre le virus de l'herpès simplex |
| CN111246854A (zh) | 2017-08-17 | 2020-06-05 | 宾夕法尼亚大学理事会 | 编码单纯疱疹病毒糖蛋白的修饰mrna疫苗及其用途 |
| BR112021018039A2 (pt) * | 2019-03-12 | 2021-11-23 | BioNTech SE | Rna terapêutico para câncer de próstata |
| CN111568856B (zh) * | 2020-06-24 | 2021-07-06 | 珠海舒桐医疗科技有限公司 | 一种阴道凝胶制剂及其制备方法 |
| EP4171629A1 (en) * | 2020-06-29 | 2023-05-03 | GlaxoSmithKline Biologicals S.A. | Adjuvants |
| US12419948B2 (en) | 2020-08-31 | 2025-09-23 | The Broad Institute, Inc. | Immunogenic compositions and use thereof |
| EP4225360A1 (en) | 2020-10-08 | 2023-08-16 | Virothera Limited | Vaccine compositions |
| EP4032546A1 (en) * | 2021-01-20 | 2022-07-27 | GlaxoSmithKline Biologicals S.A. | Therapeutic viral vaccine |
| EP4032547A1 (en) * | 2021-01-20 | 2022-07-27 | GlaxoSmithKline Biologicals S.A. | Hsv1 fce derived fragements for the treatment of hsv |
| WO2022165313A1 (en) | 2021-02-01 | 2022-08-04 | Regenxbio Inc. | Gene therapy for neuronal ceroid lipofuscinoses |
| JP2024512394A (ja) | 2021-03-11 | 2024-03-19 | レッドバイオテック・アーゲー | Ｈｓｖを処置するためのワクチン組成物及び方法 |
| CN118217388A (zh) * | 2022-12-19 | 2024-06-21 | 南京奥罗生物科技有限公司 | 单纯疱疹病毒疫苗及其应用 |
| EP4654996A1 (en) * | 2023-01-27 | 2025-12-03 | BioNTech SE | Pharmaceutical compositions for delivery of herpes simplex virus glycoprotein c, glycoprotein d, and glycoprotein e antigens and related methods |
| WO2024163918A1 (en) * | 2023-02-02 | 2024-08-08 | University Of Houston System | Mrna vaccine for herpes simplex virus |
| WO2024249967A1 (en) * | 2023-06-02 | 2024-12-05 | The Trustees Of The University Of Pennsylvania | Rna vaccines encoding herpes simplex virus glycoproteins and uses thereof |
| WO2025030165A1 (en) * | 2023-08-03 | 2025-02-06 | BioNTech SE | Pharmaceutical compositions for delivery of herpes simplex virus antigens and related methods |
| IL326358A (en) | 2023-08-03 | 2026-04-01 | Univ Pennsylvania | RNA compositions encoding herpes simplex virus glycoprotein E and/or glycoprotein I antigens and their uses |
| CN121843710A (zh) | 2023-08-03 | 2026-04-10 | 宾夕法尼亚大学理事会 | 编码单纯疱疹病毒糖蛋白b抗原的rna组合物及其用途 |
| CN121772938A (zh) * | 2023-08-03 | 2026-03-31 | 百欧恩泰欧洲股份公司 | 用于递送单纯疱疹病毒抗原的药物组合物及相关方法 |
| WO2025072383A1 (en) | 2023-09-25 | 2025-04-03 | The Broad Institute, Inc. | Viral open reading frames, uses thereof, and methods of detecting the same |
| WO2025097055A2 (en) | 2023-11-02 | 2025-05-08 | The Broad Institute, Inc. | Compositions and methods of use of t cells in immunotherapy |
| WO2025109008A1 (en) | 2023-11-20 | 2025-05-30 | Redbiotec Ag | Novel vaccine compositions and methods for treating hsv |
| WO2025129158A1 (en) | 2023-12-15 | 2025-06-19 | The Broad Institute, Inc. | Engineered arc delivery vesicles and uses thereof |
| WO2025175124A1 (en) * | 2024-02-15 | 2025-08-21 | Albert Einstein College Of Medicine | Recombinant herpes simplex virus glycoprotein b for treatment and prevention of herpes simplex virus infections |
| WO2025212831A1 (en) * | 2024-04-03 | 2025-10-09 | The Trustees Of The University Of Pennsylvania | Methods of inducing an anti-hsv b-cell immune response |
Family Cites Families (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1995026204A1 (en) | 1994-03-25 | 1995-10-05 | Isis Pharmaceuticals, Inc. | Immune stimulation by phosphorothioate oligonucleotide analogs |
| EP3611266B1 (en) | 2005-08-23 | 2022-11-09 | The Trustees of the University of Pennsylvania | Rna containing modified nucleosides and methods of use thereof |
| EP2521786B1 (en) | 2006-07-20 | 2015-06-24 | Vical Incorporated | Compositions for vaccinating against hsv-2 |
| US20130028925A1 (en) | 2006-12-28 | 2013-01-31 | Harvey Friedman | Herpes simplex virus combined subunit vaccines and methods of use thereof |
| WO2008085486A1 (en) * | 2006-12-28 | 2008-07-17 | The Trustees Of The University Of Pennsylvania | Herpes simplex virus combined subunit vaccines and methods of use thereof |
| EP3756684A1 (en) * | 2009-05-22 | 2020-12-30 | Genocea Biosciences, Inc. | Vaccines against herpes simplex virus type 2: compositions and methods for eliciting an immune response |
| CA2816925C (en) | 2009-11-04 | 2023-01-10 | The University Of British Columbia | Nucleic acid-containing lipid particles and related methods |
| US9770463B2 (en) * | 2010-07-06 | 2017-09-26 | Glaxosmithkline Biologicals Sa | Delivery of RNA to different cell types |
| US9192661B2 (en) * | 2010-07-06 | 2015-11-24 | Novartis Ag | Delivery of self-replicating RNA using biodegradable polymer particles |
| WO2012016184A2 (en) | 2010-07-30 | 2012-02-02 | Alnylam Pharmaceuticals, Inc. | Methods and compositions for delivery of active agents |
| KR102136433B1 (ko) * | 2012-05-16 | 2020-07-22 | 이뮨 디자인 코포레이션 | Hsv-2 백신 |
| AU2014362234B2 (en) * | 2013-12-11 | 2019-09-12 | The Henry M. Jackson Foundation For The Advancement Of Military Medicine, Inc. | Human herpesvirus trimeric glycoprotein B, protein complexes comprising trimeric gB and their use as vaccines |
| PE20170261A1 (es) * | 2014-05-13 | 2017-04-12 | Univ Pennsylvania | Composiciones que comprenden virus adenoasociado (aav) que expresa constructos de anticuerpos duales y sus usos |
| WO2016049705A1 (en) * | 2014-10-01 | 2016-04-07 | Admedus Vaccines Pty Ltd | Therapeutic compositions and methods for inducing an immune response to herpes simplex virus type 2 (hsv-2) |
| US20180303925A1 (en) | 2015-04-27 | 2018-10-25 | The Trustees Of The University Of Pennsylvania | Nucleoside-Modified RNA For Inducing an Adaptive Immune Response |
| US10758694B2 (en) | 2015-07-09 | 2020-09-01 | Hoyt Medical LLC | Systems and methods for treating an airway using a tapered adapter device |
| AU2016342049B2 (en) | 2015-10-22 | 2023-05-18 | Modernatx, Inc. | Herpes simplex virus vaccine |
| US20180289792A1 (en) * | 2015-10-22 | 2018-10-11 | ModernaTX. Inc. | Sexually transmitted disease vaccines |
| BR112019008481A2 (pt) * | 2016-10-26 | 2020-03-03 | Curevac Ag | Vacinas de mrna de nanopartículas lipídicas |
| MA49463A (fr) | 2017-04-26 | 2021-05-05 | Modernatx Inc | Vaccin contre le virus de l'herpès simplex |
| CN111246854A (zh) | 2017-08-17 | 2020-06-05 | 宾夕法尼亚大学理事会 | 编码单纯疱疹病毒糖蛋白的修饰mrna疫苗及其用途 |
-
2018
- 2018-08-17 CN CN201880068068.XA patent/CN111246854A/zh active Pending
- 2018-08-17 CA CA3073161A patent/CA3073161A1/en active Pending
- 2018-08-17 CN CN202410526392.9A patent/CN118370812A/zh active Pending
- 2018-08-17 EP EP23169155.1A patent/EP4242223A3/en active Pending
- 2018-08-17 JP JP2020509054A patent/JP7386535B2/ja active Active
- 2018-08-17 EP EP18846061.2A patent/EP3668520A4/en active Pending
- 2018-08-17 US US16/640,008 patent/US11141478B2/en active Active
- 2018-08-17 WO PCT/IB2018/056210 patent/WO2019035066A1/en not_active Ceased
- 2018-08-17 AU AU2018316811A patent/AU2018316811B2/en active Active
-
2021
- 2021-06-17 US US17/349,929 patent/US11793872B2/en active Active
-
2023
- 2023-08-28 JP JP2023138084A patent/JP7674760B2/ja active Active
- 2023-09-19 US US18/470,325 patent/US20240024463A1/en active Pending
- 2023-10-13 AU AU2023248194A patent/AU2023248194A1/en active Pending
-
2025
- 2025-04-18 JP JP2025069088A patent/JP2025108645A/ja active Pending
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2023153423A5 (https=) | ||
| JP2025108645A5 (https=) | ||
| JP2020531465A5 (https=) | ||
| KR101746872B1 (ko) | 단순 포진 바이러스 유형 2에 대한 백신: 면역 반응을 유도하는 조성물 및 방법 | |
| JP6790189B2 (ja) | Ｈｓｖ−２のためのワクチン | |
| AU2018316811B2 (en) | Modified mRNA vaccines encoding herpes simplex virus glycoproteins and uses thereof | |
| Bourne et al. | DNA immunization against experimental genital herpes simplex virus infection | |
| EP2413963B1 (en) | Methods of use for hsv-1 and hsv-2 vaccines | |
| JP2022547313A (ja) | ヒトサイトメガロウイルスワクチン | |
| WO2023107999A2 (en) | Herpes simplex virus mrna vaccines | |
| KR20180094859A (ko) | 수두 대상포진 바이러스 (vzv)를 위한 핵산 백신 | |
| JP5845191B2 (ja) | 単純ヘルペスウイルスワクチン | |
| Wachsman et al. | A growth and latency compromised herpes simplex virus type 2 mutant (ICP10ΔPK) has prophylactic and therapeutic protective activity in guinea pigs | |
| Mertz et al. | Herpes simplex virus type-2 glycoprotein-subunit vaccine: tolerance and humoral and cellular responses in humans | |
| Bright et al. | The efficacy of HSV-2 vaccines based on gD and gB is enhanced by the addition of ICP27 | |
| JP7844442B2 (ja) | ヒトサイトメガロウイルスワクチン | |
| LeBlanc et al. | The comparative effects of famciclovir and valacyclovir on herpes simplex virus type 1 infection, latency, and reactivation in mice | |
| US20240156951A1 (en) | Vaccine compositions and methods for treating hsv | |
| Lewis et al. | Structural and antigenic identification of the ORF12 protein (αTIF) of equine herpesvirus 1 | |
| JP2014534262A5 (https=) | ||
| US20240016922A1 (en) | Rna vaccines encoding herpes simplex virus glycoproteins and uses thereof | |
| CN121843710A (zh) | 编码单纯疱疹病毒糖蛋白b抗原的rna组合物及其用途 | |
| Bernstein et al. | A vaccine containing highly purified virus particles in adjuvant provides high level protection against genital infection and disease in guinea pigs challenged intravaginally with homologous and heterologous strains of herpes simplex virus type 2 | |
| US10166284B1 (en) | Vaccines for herpes simplex virus 1 and 2 | |
| Rooney et al. | Live vaccinia virus recombinants expressing herpes simplex virus genes |