CN111246854A - 编码单纯疱疹病毒糖蛋白的修饰mrna疫苗及其用途 - Google Patents

编码单纯疱疹病毒糖蛋白的修饰mrna疫苗及其用途 Download PDF

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CN111246854A
CN111246854A CN201880068068.XA CN201880068068A CN111246854A CN 111246854 A CN111246854 A CN 111246854A CN 201880068068 A CN201880068068 A CN 201880068068A CN 111246854 A CN111246854 A CN 111246854A
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hsv
another embodiment
composition
modified mrna
pro
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H·弗里德曼
D·韦斯曼
S·阿瓦斯蒂
G·科恩
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University of Pennsylvania Penn
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    • A61K39/00—Medicinal preparations containing antigens or antibodies
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    • C12N2710/16011—Herpesviridae
    • C12N2710/16611—Simplexvirus, e.g. human herpesvirus 1, 2
    • C12N2710/16634—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein

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CN201880068068.XA 2017-08-17 2018-08-17 编码单纯疱疹病毒糖蛋白的修饰mrna疫苗及其用途 Pending CN111246854A (zh)

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CN202410526392.9A CN118370812A (zh) 2017-08-17 2018-08-17 编码单纯疱疹病毒糖蛋白的修饰mrna疫苗及其用途

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US201762546648P 2017-08-17 2017-08-17
US62/546,648 2017-08-17
US201862701019P 2018-07-20 2018-07-20
US62/701,019 2018-07-20
PCT/IB2018/056210 WO2019035066A1 (en) 2017-08-17 2018-08-17 MODIFIED MHRNA VACCINES ENCODING HERPES SIMPLEX VIRUS GLYCOPROTEINS AND USES THEREOF

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CN202410526392.9A Pending CN118370812A (zh) 2017-08-17 2018-08-17 编码单纯疱疹病毒糖蛋白的修饰mrna疫苗及其用途

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US (3) US11141478B2 (https=)
EP (2) EP4242223A3 (https=)
JP (3) JP7386535B2 (https=)
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AU (2) AU2018316811B2 (https=)
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WO2024131664A1 (zh) * 2022-12-19 2024-06-27 南京奥罗生物科技有限公司 单纯疱疹病毒疫苗及其应用

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BR112021018039A2 (pt) * 2019-03-12 2021-11-23 BioNTech SE Rna terapêutico para câncer de próstata
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EP4225360A1 (en) 2020-10-08 2023-08-16 Virothera Limited Vaccine compositions
EP4032546A1 (en) * 2021-01-20 2022-07-27 GlaxoSmithKline Biologicals S.A. Therapeutic viral vaccine
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WO2022165313A1 (en) 2021-02-01 2022-08-04 Regenxbio Inc. Gene therapy for neuronal ceroid lipofuscinoses
JP2024512394A (ja) 2021-03-11 2024-03-19 レッドバイオテック・アーゲー Ｈｓｖを処置するためのワクチン組成物及び方法
EP4654996A1 (en) * 2023-01-27 2025-12-03 BioNTech SE Pharmaceutical compositions for delivery of herpes simplex virus glycoprotein c, glycoprotein d, and glycoprotein e antigens and related methods
WO2024163918A1 (en) * 2023-02-02 2024-08-08 University Of Houston System Mrna vaccine for herpes simplex virus
WO2024249967A1 (en) * 2023-06-02 2024-12-05 The Trustees Of The University Of Pennsylvania Rna vaccines encoding herpes simplex virus glycoproteins and uses thereof
WO2025030165A1 (en) * 2023-08-03 2025-02-06 BioNTech SE Pharmaceutical compositions for delivery of herpes simplex virus antigens and related methods
IL326358A (en) 2023-08-03 2026-04-01 Univ Pennsylvania RNA compositions encoding herpes simplex virus glycoprotein E and/or glycoprotein I antigens and their uses
CN121843710A (zh) 2023-08-03 2026-04-10 宾夕法尼亚大学理事会 编码单纯疱疹病毒糖蛋白b抗原的rna组合物及其用途
CN121772938A (zh) * 2023-08-03 2026-03-31 百欧恩泰欧洲股份公司 用于递送单纯疱疹病毒抗原的药物组合物及相关方法
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WO2025175124A1 (en) * 2024-02-15 2025-08-21 Albert Einstein College Of Medicine Recombinant herpes simplex virus glycoprotein b for treatment and prevention of herpes simplex virus infections
WO2025212831A1 (en) * 2024-04-03 2025-10-09 The Trustees Of The University Of Pennsylvania Methods of inducing an anti-hsv b-cell immune response

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Cited By (3)

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Publication number Priority date Publication date Assignee Title
CN111568856A (zh) * 2020-06-24 2020-08-25 珠海舒桐医疗科技有限公司 一种阴道凝胶制剂及其制备方法
CN111568856B (zh) * 2020-06-24 2021-07-06 珠海舒桐医疗科技有限公司 一种阴道凝胶制剂及其制备方法
WO2024131664A1 (zh) * 2022-12-19 2024-06-27 南京奥罗生物科技有限公司 单纯疱疹病毒疫苗及其应用

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EP4242223A2 (en) 2023-09-13
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US20200276300A1 (en) 2020-09-03
CA3073161A1 (en) 2019-02-21
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AU2018316811B2 (en) 2023-07-13
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AU2018316811A1 (en) 2020-03-12
EP3668520A1 (en) 2020-06-24
AU2023248194A1 (en) 2023-11-02
WO2019035066A1 (en) 2019-02-21
US20240024463A1 (en) 2024-01-25
JP2023153423A (ja) 2023-10-17

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