JP2023134542A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2023134542A5 JP2023134542A5 JP2023108111A JP2023108111A JP2023134542A5 JP 2023134542 A5 JP2023134542 A5 JP 2023134542A5 JP 2023108111 A JP2023108111 A JP 2023108111A JP 2023108111 A JP2023108111 A JP 2023108111A JP 2023134542 A5 JP2023134542 A5 JP 2023134542A5
- Authority
- JP
- Japan
- Prior art keywords
- patient
- neoantigens
- neoantigen
- presentation
- peptide sequence
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2025039865A JP2025094018A (ja) | 2017-06-09 | 2025-03-13 | 新生抗原の特定、製造、及び使用 |
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201762517786P | 2017-06-09 | 2017-06-09 | |
| US62/517,786 | 2017-06-09 | ||
| JP2019567557A JP7795291B2 (ja) | 2017-06-09 | 2018-06-08 | 新生抗原の特定、製造、及び使用 |
| PCT/US2018/036571 WO2018227030A1 (en) | 2017-06-09 | 2018-06-08 | Neoantigen identification, manufacture, and use |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019567557A Division JP7795291B2 (ja) | 2017-06-09 | 2018-06-08 | 新生抗原の特定、製造、及び使用 |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2025039865A Division JP2025094018A (ja) | 2017-06-09 | 2025-03-13 | 新生抗原の特定、製造、及び使用 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2023134542A JP2023134542A (ja) | 2023-09-27 |
| JP2023134542A5 true JP2023134542A5 (https=) | 2024-07-16 |
| JP7651623B2 JP7651623B2 (ja) | 2025-03-26 |
Family
ID=64566322
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019567557A Active JP7795291B2 (ja) | 2017-06-09 | 2018-06-08 | 新生抗原の特定、製造、及び使用 |
| JP2023108111A Active JP7651623B2 (ja) | 2017-06-09 | 2023-06-30 | 新生抗原の特定、製造、及び使用 |
| JP2025039865A Pending JP2025094018A (ja) | 2017-06-09 | 2025-03-13 | 新生抗原の特定、製造、及び使用 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019567557A Active JP7795291B2 (ja) | 2017-06-09 | 2018-06-08 | 新生抗原の特定、製造、及び使用 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2025039865A Pending JP2025094018A (ja) | 2017-06-09 | 2025-03-13 | 新生抗原の特定、製造、及び使用 |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US20200105377A1 (https=) |
| EP (2) | EP3635594B1 (https=) |
| JP (3) | JP7795291B2 (https=) |
| KR (2) | KR20240165471A (https=) |
| CN (1) | CN110720127A (https=) |
| AU (1) | AU2018279627B2 (https=) |
| CA (1) | CA3066635A1 (https=) |
| IL (1) | IL271038A (https=) |
| SG (1) | SG11201911620PA (https=) |
| WO (1) | WO2018227030A1 (https=) |
Families Citing this family (32)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2014180490A1 (en) | 2013-05-10 | 2014-11-13 | Biontech Ag | Predicting immunogenicity of t cell epitopes |
| WO2016128060A1 (en) | 2015-02-12 | 2016-08-18 | Biontech Ag | Predicting t cell epitopes useful for vaccination |
| RU2729116C2 (ru) | 2015-12-16 | 2020-08-04 | Гритстоун Онколоджи, Инк. | Идентификация, производство и применение неоантигенов |
| WO2017194170A1 (en) | 2016-05-13 | 2017-11-16 | Biontech Rna Pharmaceuticals Gmbh | Methods for predicting the usefulness of proteins or protein fragments for immunotherapy |
| MX2019013259A (es) | 2017-05-08 | 2020-01-13 | Gritstone Oncology Inc | Vectores de neoantigeno de alfavirus. |
| WO2018224166A1 (en) | 2017-06-09 | 2018-12-13 | Biontech Rna Pharmaceuticals Gmbh | Methods for predicting the usefulness of disease specific amino acid modifications for immunotherapy |
| KR20260039788A (ko) | 2017-10-10 | 2026-03-20 | 시애틀 프로젝트 코포레이션 | 핫스팟을 이용한 신생항원 동정 |
| CA3083097A1 (en) | 2017-11-22 | 2019-05-31 | Gritstone Oncology, Inc. | Reducing junction epitope presentation for neoantigens |
| CN112368386A (zh) * | 2018-05-23 | 2021-02-12 | 磨石肿瘤生物技术公司 | 共有抗原 |
| US11599774B2 (en) * | 2019-03-29 | 2023-03-07 | International Business Machines Corporation | Training machine learning model |
| MX2021014525A (es) | 2019-05-30 | 2022-03-17 | Gritstone Bio Inc | Adenovirus modificados. |
| CN114761041A (zh) | 2019-07-16 | 2022-07-15 | 吉利德科学公司 | Hiv疫苗及其制备和使用方法 |
| CN111303268B (zh) * | 2020-03-10 | 2021-08-27 | 江苏兰恩生物治疗技术研究院有限公司 | 子宫肌瘤新抗原、其应用和子宫肌瘤疫苗 |
| KR102159921B1 (ko) * | 2020-03-24 | 2020-09-25 | 주식회사 테라젠바이오 | 펩타이드 서열 및 hla 대립유전자 서열을 이용하여 신생항원을 예측하는 방법 및 컴퓨터 프로그램 |
| WO2022013154A1 (en) * | 2020-07-14 | 2022-01-20 | Myneo Nv | Method, system and computer program product for determining presentation likelihoods of neoantigens |
| KR20230046313A (ko) | 2020-08-06 | 2023-04-05 | 그릿스톤 바이오, 인코포레이티드 | 다중에피토프 백신 카세트 |
| CN112210596B (zh) * | 2020-09-08 | 2022-04-26 | 中生康元生物科技(北京)有限公司 | 基于基因融合事件的肿瘤新生抗原预测方法及其应用 |
| CN114333998B (zh) * | 2020-10-10 | 2024-10-15 | 格源致善(上海)生物科技有限公司 | 一种基于深度学习模型的肿瘤新抗原预测方法及新生抗原预测系统 |
| CN112309502B (zh) * | 2020-10-14 | 2024-09-20 | 深圳市新合生物医疗科技有限公司 | 一种计算肿瘤新抗原负荷的方法及系统 |
| EP4213158A1 (en) | 2020-11-13 | 2023-07-19 | Ahead Biocomputing, Co. Ltd | Information processing device, information processing method, recording medium recording information processing program, and information processing system |
| EP4277652A1 (en) | 2021-01-14 | 2023-11-22 | Gilead Sciences, Inc. | Hiv vaccines and methods of using |
| JP7057003B1 (ja) | 2021-02-26 | 2022-04-19 | 国立大学法人東京工業大学 | 予測装置、学習済みモデルの生成装置、予測方法、学習済みモデルの生成方法、予測プログラム、及び学習済みモデルの生成プログラム |
| JP7057004B1 (ja) | 2021-03-05 | 2022-04-19 | 国立大学法人東京工業大学 | 予測装置、学習済みモデルの生成装置、予測方法、学習済みモデルの生成方法、予測プログラム、及び学習済みモデルの生成プログラム |
| WO2022197630A1 (en) * | 2021-03-15 | 2022-09-22 | Amazon Technologies, Inc. | Methods for optimizing tumor vaccine antigen coverage for heterogenous malignancies |
| CA3216276A1 (en) | 2021-04-29 | 2022-11-03 | Yardena Samuels | T cell receptors directed against ras-derived recurrent neoantigens and methods of identifying same |
| EP4148146A1 (en) * | 2021-09-13 | 2023-03-15 | OncoDNA | Method to generate personalized neoantigens of a tumor of a patient |
| JP2024533501A (ja) * | 2021-09-13 | 2024-09-12 | オンコディーエヌエー | 患者の腫瘍の個別化された新生抗原を生成する方法 |
| CN117690495A (zh) * | 2023-12-15 | 2024-03-12 | 南京鼓楼医院 | 一种肿瘤新抗原预测方法、系统、电子设备及存储介质 |
| CN117711487B (zh) * | 2024-02-05 | 2024-05-17 | 广州嘉检医学检测有限公司 | 胚系SNV、InDel变异的鉴定方法、系统以及可读存储介质 |
| CN118262793B (zh) * | 2024-03-05 | 2025-01-03 | 复旦大学附属肿瘤医院 | 一种选择多价肿瘤新抗原组合系统和方法 |
| WO2025207836A1 (en) * | 2024-03-26 | 2025-10-02 | Wenyi Wang | Methods for selecting cancer patients for immunotherapy using subclonal mutation analysis |
| CN118351934B (zh) * | 2024-04-26 | 2025-01-28 | 广州润生细胞医药科技有限责任公司 | 一种基于二代测序数据的肿瘤新抗原识别方法及系统 |
Family Cites Families (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4235871A (en) | 1978-02-24 | 1980-11-25 | Papahadjopoulos Demetrios P | Method of encapsulating biologically active materials in lipid vesicles |
| US4722848A (en) | 1982-12-08 | 1988-02-02 | Health Research, Incorporated | Method for immunizing animals with synthetically modified vaccinia virus |
| US4501728A (en) | 1983-01-06 | 1985-02-26 | Technology Unlimited, Inc. | Masking of liposomes from RES recognition |
| GB8311018D0 (en) | 1983-04-22 | 1983-05-25 | Amersham Int Plc | Detecting mutations in dna |
| US5019369A (en) | 1984-10-22 | 1991-05-28 | Vestar, Inc. | Method of targeting tumors in humans |
| US4837028A (en) | 1986-12-24 | 1989-06-06 | Liposome Technology, Inc. | Liposomes with enhanced circulation time |
| US5703055A (en) | 1989-03-21 | 1997-12-30 | Wisconsin Alumni Research Foundation | Generation of antibodies through lipid mediated DNA delivery |
| FR2650840B1 (fr) | 1989-08-11 | 1991-11-29 | Bertin & Cie | Procede rapide de detection et/ou d'identification d'une seule base sur une sequence d'acide nucleique, et ses applications |
| ATE157012T1 (de) | 1989-11-03 | 1997-09-15 | Univ Vanderbilt | Verfahren zur in vivo-verabreichung von funktionsfähigen fremden genen |
| US5279833A (en) | 1990-04-04 | 1994-01-18 | Yale University | Liposomal transfection of nucleic acids into animal cells |
| US5204253A (en) | 1990-05-29 | 1993-04-20 | E. I. Du Pont De Nemours And Company | Method and apparatus for introducing biological substances into living cells |
| EP0646178A1 (en) | 1992-06-04 | 1995-04-05 | The Regents Of The University Of California | expression cassette with regularoty regions functional in the mammmlian host |
| US5849589A (en) | 1996-03-11 | 1998-12-15 | Duke University | Culturing monocytes with IL-4, TNF-α and GM-CSF TO induce differentiation to dendric cells |
| US7220549B2 (en) | 2004-12-30 | 2007-05-22 | Helicos Biosciences Corporation | Stabilizing a nucleic acid for nucleic acid sequencing |
| US7283337B2 (en) | 2005-03-04 | 2007-10-16 | Headway Technologies, Inc. | Abutted exchange bias design for sensor stabilization |
| CA2879024A1 (en) * | 2012-07-12 | 2014-01-16 | Persimmune, Inc. | Personalized cancer vaccines and adoptive immune cell therapies |
| CN118750591A (zh) * | 2013-04-07 | 2024-10-11 | 博德研究所 | 用于个性化瘤形成疫苗的组合物和方法 |
-
2018
- 2018-06-08 CN CN201880037822.3A patent/CN110720127A/zh active Pending
- 2018-06-08 KR KR1020247037251A patent/KR20240165471A/ko active Pending
- 2018-06-08 CA CA3066635A patent/CA3066635A1/en active Pending
- 2018-06-08 EP EP18814074.3A patent/EP3635594B1/en active Active
- 2018-06-08 EP EP24205415.3A patent/EP4512817A3/en active Pending
- 2018-06-08 US US16/619,652 patent/US20200105377A1/en active Pending
- 2018-06-08 JP JP2019567557A patent/JP7795291B2/ja active Active
- 2018-06-08 SG SG11201911620PA patent/SG11201911620PA/en unknown
- 2018-06-08 KR KR1020197036968A patent/KR102729393B1/ko active Active
- 2018-06-08 WO PCT/US2018/036571 patent/WO2018227030A1/en not_active Ceased
- 2018-06-08 AU AU2018279627A patent/AU2018279627B2/en active Active
-
2019
- 2019-11-28 IL IL271038A patent/IL271038A/en unknown
-
2023
- 2023-06-30 JP JP2023108111A patent/JP7651623B2/ja active Active
-
2025
- 2025-03-13 JP JP2025039865A patent/JP2025094018A/ja active Pending
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2023134542A5 (https=) | ||
| JP2025094018A5 (https=) | ||
| JP2025065197A5 (https=) | ||
| JP2020536553A5 (https=) | ||
| JP2025143480A5 (https=) | ||
| JP2020532323A5 (https=) | ||
| JPWO2019168984A5 (https=) | ||
| Smith et al. | The sea lamprey germline genome provides insights into programmed genome rearrangement and vertebrate evolution | |
| JP7606528B2 (ja) | ペプチド及びｈｌａ対立遺伝子配列を用いて新生抗原を予測する方法及びコンピュータプログラム | |
| JP2021503897A5 (https=) | ||
| RU2019136762A (ru) | Идентификация, производство и применение неоантигенов | |
| Tan et al. | The whale shark genome reveals patterns of vertebrate gene family evolution | |
| JPWO2020181240A5 (https=) | ||
| US20260057964A1 (en) | Method and system of targeting epitopes for neoantigen-based immunotherapy | |
| CN118685530B (zh) | 一种非典型新抗原的筛选方法 | |
| Codner et al. | Constraints on haplotype structure and variable gene frequencies suggest a functional hierarchy within cattle MHC class I | |
| JP2024178175A5 (https=) | ||
| Yoshida et al. | Genome structure analysis of molluscs revealed whole genome duplication and lineage specific repeat variation | |
| CN114929899A (zh) | 一种新抗原的筛选方法、系统及其用途 | |
| Gilchrist et al. | A pipeline for the systematic identification of non-redundant full-ORF cDNAs for polymorphic and evolutionary divergent genomes: Application to the ascidian Ciona intestinalis | |
| CN111696628A (zh) | 新生抗原的鉴定方法 | |
| CN115747327A (zh) | 涉及移码突变的新抗原预测方法 | |
| Soni et al. | A whole-genome scan for evidence of positive and balancing selection in aye-ayes (Daubentonia madagascariensis) utilizing a well-fit evolutionary baseline model | |
| JPWO2022207925A5 (https=) | ||
| NZ759958B2 (en) | Neoantigen identification, manufacture, and use |