JP2024505638A5 - - Google Patents
Info
- Publication number
- JP2024505638A5 JP2024505638A5 JP2023543396A JP2023543396A JP2024505638A5 JP 2024505638 A5 JP2024505638 A5 JP 2024505638A5 JP 2023543396 A JP2023543396 A JP 2023543396A JP 2023543396 A JP2023543396 A JP 2023543396A JP 2024505638 A5 JP2024505638 A5 JP 2024505638A5
- Authority
- JP
- Japan
- Prior art keywords
- tumor
- mhc class
- specific
- peptide
- specific neoantigen
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202163139074P | 2021-01-19 | 2021-01-19 | |
| US63/139,074 | 2021-01-19 | ||
| PCT/US2021/061399 WO2022159176A1 (en) | 2021-01-19 | 2021-12-01 | A deep learning model for predicting tumor-specific neoantigen mhc class i or class ii immunogenicity |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2024505638A JP2024505638A (ja) | 2024-02-07 |
| JP2024505638A5 true JP2024505638A5 (https=) | 2024-12-10 |
Family
ID=80122521
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023543396A Pending JP2024505638A (ja) | 2021-01-19 | 2021-12-01 | 腫瘍特異的ネオアンチゲンのｍｈｃクラスｉまたはクラスｉｉ免疫原性を予測するためのディープラーニングモデル |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US12567480B2 (https=) |
| EP (1) | EP4281970A1 (https=) |
| JP (1) | JP2024505638A (https=) |
| CN (1) | CN117136410A (https=) |
| WO (1) | WO2022159176A1 (https=) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN116959581A (zh) * | 2023-01-17 | 2023-10-27 | 腾讯科技（深圳）有限公司 | 免疫原性预测模型的训练方法、装置、设备及存储介质 |
| KR20250058439A (ko) * | 2023-10-23 | 2025-04-30 | 주식회사 Lg 경영개발원 | 비관측 단백질 복합체를 활용하여 항원 제시 모델을 생성하는 단백질 상호 작용 예측 장치 및 이를 이용한 방법 |
| WO2025128926A1 (en) | 2023-12-13 | 2025-06-19 | Amazon Technologies, Inc. | Methods of identifying and treating individuals with elevated cancer risk |
| US20250197924A1 (en) | 2023-12-15 | 2025-06-19 | Amazon Technologies, Inc. | Methods for selection and combination of sequencing results from biological samples for neoantigen scoring |
| CN117877603B (zh) * | 2024-01-11 | 2024-09-13 | 天津大学 | 一种基于分层信息提取机制的化学反应理论产量预测方法 |
| WO2026072916A1 (en) | 2024-09-30 | 2026-04-02 | Amazon Technologies, Inc. | Structural variant detection in circulating tumor dna |
| WO2026073127A1 (en) | 2024-09-30 | 2026-04-02 | Amazon Technologies, Inc. | Dual assay to boost accuracy of detected actionable variants in liquid biopsy |
| CN119152945A (zh) * | 2024-10-08 | 2024-12-17 | 中国人民解放军海军军医大学第一附属医院 | 一种NeoBert模型及其在鉴别肿瘤新抗原中的应用 |
| CN120048333B (zh) * | 2025-02-14 | 2025-10-21 | 三二〇一医院 | 一种新抗原的筛选方法、设备及程序产品 |
| CN119964812A (zh) * | 2025-04-10 | 2025-05-09 | 成都大学附属医院(成都市创伤骨科研究所) | 基于深度学习的前列腺癌医学智能预测系统 |
Family Cites Families (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4235871A (en) | 1978-02-24 | 1980-11-25 | Papahadjopoulos Demetrios P | Method of encapsulating biologically active materials in lipid vesicles |
| US4722848A (en) | 1982-12-08 | 1988-02-02 | Health Research, Incorporated | Method for immunizing animals with synthetically modified vaccinia virus |
| US4501728A (en) | 1983-01-06 | 1985-02-26 | Technology Unlimited, Inc. | Masking of liposomes from RES recognition |
| US5019369A (en) | 1984-10-22 | 1991-05-28 | Vestar, Inc. | Method of targeting tumors in humans |
| US4837028A (en) | 1986-12-24 | 1989-06-06 | Liposome Technology, Inc. | Liposomes with enhanced circulation time |
| US5057540A (en) | 1987-05-29 | 1991-10-15 | Cambridge Biotech Corporation | Saponin adjuvant |
| US4912094B1 (en) | 1988-06-29 | 1994-02-15 | Ribi Immunochem Research Inc. | Modified lipopolysaccharides and process of preparation |
| US5703055A (en) | 1989-03-21 | 1997-12-30 | Wisconsin Alumni Research Foundation | Generation of antibodies through lipid mediated DNA delivery |
| US5204253A (en) | 1990-05-29 | 1993-04-20 | E. I. Du Pont De Nemours And Company | Method and apparatus for introducing biological substances into living cells |
| US8063063B2 (en) | 2006-03-23 | 2011-11-22 | Novartis Ag | Immunopotentiating compounds |
| ES2536426T3 (es) | 2006-03-23 | 2015-05-25 | Novartis Ag | Compuestos de imidazoquinoxalina como inmunomoduladores |
| ES2970865T3 (es) * | 2015-12-16 | 2024-05-31 | Gritstone Bio Inc | Identificación, fabricación y uso de neoantígenos |
| EP3759131A4 (en) * | 2018-02-27 | 2021-12-01 | Gritstone bio, Inc. | NEOANTIGEN IDENTIFICATION WITH PAN ALLELE MODELS |
| EP3930755A4 (en) * | 2019-03-01 | 2023-03-22 | Flow Pharma Inc. | DESIGN, MANUFACTURE AND USE OF PERSONALIZED CANCER VACCINES |
| EP3739589A1 (en) * | 2019-05-17 | 2020-11-18 | NEC OncoImmunity AS | Method and system for binding affinity prediction and method of generating a candidate protein-binding peptide |
| CN111415707B (zh) * | 2020-03-10 | 2023-04-25 | 四川大学 | 临床个体化肿瘤新抗原的预测方法 |
| CN112071361B (zh) * | 2020-04-11 | 2024-05-24 | 信华生物药业(广州)有限公司 | 基于Bi-LSTM与Self-Attention的多肽TCR免疫原性预测方法 |
| CN112002374B (zh) * | 2020-06-14 | 2022-04-22 | 北京臻知医学科技有限责任公司 | 基于深度学习的mhc-i表位亲和力预测方法 |
-
2021
- 2021-12-01 CN CN202180095858.9A patent/CN117136410A/zh active Pending
- 2021-12-01 JP JP2023543396A patent/JP2024505638A/ja active Pending
- 2021-12-01 WO PCT/US2021/061399 patent/WO2022159176A1/en not_active Ceased
- 2021-12-01 EP EP21851718.3A patent/EP4281970A1/en active Pending
- 2021-12-01 US US17/617,665 patent/US12567480B2/en active Active
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