JP2023109996A5 - - Google Patents
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- Publication number
- JP2023109996A5 JP2023109996A5 JP2023089684A JP2023089684A JP2023109996A5 JP 2023109996 A5 JP2023109996 A5 JP 2023109996A5 JP 2023089684 A JP2023089684 A JP 2023089684A JP 2023089684 A JP2023089684 A JP 2023089684A JP 2023109996 A5 JP2023109996 A5 JP 2023109996A5
- Authority
- JP
- Japan
- Prior art keywords
- vaccine
- functional
- live attenuated
- deleted
- bordetella strain
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 229960005486 vaccine Drugs 0.000 claims 15
- 241000588807 Bordetella Species 0.000 claims 8
- 230000002238 attenuated effect Effects 0.000 claims 8
- APUIQTDTBPKWKE-RNPGEKFLSA-N (2r,6s)-6-[[(4r)-4-[[(2s)-2-[2-[[(1r,2s,3r,4r,5r)-4-acetamido-2-[(2s,3r,4r,5s,6r)-3-acetamido-4,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-6,8-dioxabicyclo[3.2.1]octan-3-yl]oxy]propanoylamino]propanoyl]amino]-4-carboxybutanoyl]amino]-2-amino-7-[[(2r)-2-am Chemical compound O([C@@H]1[C@H]2CO[C@H](O2)[C@H](NC(C)=O)[C@H]1OC(C)C(=O)N[C@@H](C)C(=O)N[C@H](CCC(=O)N[C@@H](CCC[C@@H](N)C(O)=O)C(=O)NC(=O)[C@H](N)C)C(O)=O)[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1NC(C)=O APUIQTDTBPKWKE-RNPGEKFLSA-N 0.000 claims 5
- 108700039691 Genetic Promoter Regions Proteins 0.000 claims 3
- 108090000623 proteins and genes Proteins 0.000 claims 3
- 208000018150 Bordetella infection Diseases 0.000 claims 2
- 201000005702 Pertussis Diseases 0.000 claims 2
- 108010081690 Pertussis Toxin Proteins 0.000 claims 2
- OPTASPLRGRRNAP-UHFFFAOYSA-N cytosine Chemical compound NC=1C=CNC(=O)N=1 OPTASPLRGRRNAP-UHFFFAOYSA-N 0.000 claims 2
- 239000002552 dosage form Substances 0.000 claims 2
- 239000000304 virulence factor Substances 0.000 claims 2
- 230000007923 virulence factor Effects 0.000 claims 2
- 230000004913 activation Effects 0.000 claims 1
- 230000001332 colony forming effect Effects 0.000 claims 1
- 229940104302 cytosine Drugs 0.000 claims 1
- 239000003937 drug carrier Substances 0.000 claims 1
- 230000002500 effect on skin Effects 0.000 claims 1
- 230000028993 immune response Effects 0.000 claims 1
- 210000004072 lung Anatomy 0.000 claims 1
- 230000001404 mediated effect Effects 0.000 claims 1
- 230000001338 necrotic effect Effects 0.000 claims 1
- 230000001681 protective effect Effects 0.000 claims 1
- 239000003053 toxin Substances 0.000 claims 1
- 231100000765 toxin Toxicity 0.000 claims 1
- 230000035897 transcription Effects 0.000 claims 1
- 238000013518 transcription Methods 0.000 claims 1
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201762574068P | 2017-10-18 | 2017-10-18 | |
| US62/574,068 | 2017-10-18 | ||
| JP2020520777A JP7335874B2 (ja) | 2017-10-18 | 2018-10-18 | 血清型３線毛を発現するボルデテラ（ｂｏｒｄｅｔｅｌｌａ）菌株 |
| PCT/EP2018/078522 WO2019077028A1 (en) | 2017-10-18 | 2018-10-18 | BORDETELLA STRAINS EXPRESSING SERO-TYPE FIMBRIAE 3 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020520777A Division JP7335874B2 (ja) | 2017-10-18 | 2018-10-18 | 血清型３線毛を発現するボルデテラ（ｂｏｒｄｅｔｅｌｌａ）菌株 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2023109996A JP2023109996A (ja) | 2023-08-08 |
| JP2023109996A5 true JP2023109996A5 (enExample) | 2023-11-28 |
Family
ID=64664226
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020520777A Active JP7335874B2 (ja) | 2017-10-18 | 2018-10-18 | 血清型３線毛を発現するボルデテラ（ｂｏｒｄｅｔｅｌｌａ）菌株 |
| JP2023089684A Pending JP2023109996A (ja) | 2017-10-18 | 2023-05-31 | 血清型３線毛を発現するボルデテラ（ｂｏｒｄｅｔｅｌｌａ）菌株 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020520777A Active JP7335874B2 (ja) | 2017-10-18 | 2018-10-18 | 血清型３線毛を発現するボルデテラ（ｂｏｒｄｅｔｅｌｌａ）菌株 |
Country Status (8)
| Country | Link |
|---|---|
| US (2) | US11446372B2 (enExample) |
| EP (1) | EP3697439A1 (enExample) |
| JP (2) | JP7335874B2 (enExample) |
| CN (2) | CN118979003A (enExample) |
| AU (1) | AU2018353409B2 (enExample) |
| CA (1) | CA3077428A1 (enExample) |
| SG (1) | SG11202003333WA (enExample) |
| WO (1) | WO2019077028A1 (enExample) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3800244A1 (en) * | 2006-03-10 | 2021-04-07 | Institut Pasteur de Lille | Live attenuated bordetella strains as a single dose vaccine against whooping cough |
| WO2010125014A1 (en) | 2009-04-28 | 2010-11-04 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Vaccine for prophylaxis or treatment of an allergen-driven airway pathology |
| CA3077428A1 (en) * | 2017-10-18 | 2019-04-25 | Institut Pasteur De Lille | Bordetella strains expressing serotype 3 fimbriae |
| CA3195783A1 (en) | 2020-11-17 | 2022-05-27 | Keith Rubin | Treatment and prevention of neuropathology associated with neurodegenerative diseases |
Family Cites Families (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4883761A (en) * | 1986-03-25 | 1989-11-28 | The United States Of America As Represented By The Department Of Health And Human Services | Pertussis toxin gene: cloning and expression of protective antigen |
| US6713072B1 (en) | 1987-11-02 | 2004-03-30 | Chiron S.R.L. | Immunologically active polypeptides with altered toxicity useful for the preparation of an antipertussis vaccine |
| IT1236971B (it) * | 1989-11-03 | 1993-05-07 | Eniricerche Spa | Regione promotore dei geni codificanti le subunita' piliniche fim2, fm3 e fimx di bordetella pertussis e loro impiego per l'espressione di geni che codificano una proteina di interesse. |
| GB9115332D0 (en) | 1991-07-16 | 1991-08-28 | Connaught Lab | Manipulation of gene copy number in bordetella |
| FR2718750B1 (fr) | 1994-04-19 | 1996-06-14 | Pasteur Institut | Protéines recombinantes de l'hémagglutinine filamenteuse de Bordetella, notamment, B. Pertussis, production et application à la production de protéines étrangères ou de principes actifs vaccinants. |
| FR2754543B1 (fr) * | 1996-10-11 | 1998-12-31 | Pasteur Institut | Souche de bordetella deficiente dans la production de toxine et exprimant une proteine hydride, liposomes comprenant de la fha et leurs utilisations comme vaccins, et utilisation de la fha pour stimuler les reponses immunitaires |
| FR2840319B1 (fr) | 2002-05-30 | 2004-08-20 | Pasteur Institut | Souches de bordetella rendues deficientes par attenuation genetique |
| WO2004091519A2 (en) | 2003-04-11 | 2004-10-28 | Medimmune, Inc. | Methods of preventing or treating respiratory conditions |
| GB0402131D0 (en) * | 2004-01-30 | 2004-03-03 | Isis Innovation | Delivery method |
| EP3800244A1 (en) * | 2006-03-10 | 2021-04-07 | Institut Pasteur de Lille | Live attenuated bordetella strains as a single dose vaccine against whooping cough |
| WO2008058396A1 (en) | 2006-11-15 | 2008-05-22 | Folia Biotech Inc. | Papaya mosaic virus-based vaccines for influenza |
| EP2134359A4 (en) | 2007-02-23 | 2010-06-16 | Penn State Res Found | USE OF A NONVIRULENT BORDETELLA MUTANT AS LIVING VACCINE VECTOR |
| CN100537767C (zh) * | 2007-04-29 | 2009-09-09 | 中国药品生物制品检定所 | 百日咳疫苗保护性抗原的重组表达及其应用 |
| AU2008266910A1 (en) | 2007-06-18 | 2008-12-24 | Hemispherx Biopharma, Inc. | Early intervention of viral infections with immune activators |
| WO2010125014A1 (en) * | 2009-04-28 | 2010-11-04 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Vaccine for prophylaxis or treatment of an allergen-driven airway pathology |
| CN102802665B (zh) | 2009-06-15 | 2015-11-25 | 新加坡国立大学 | 流感疫苗、组合物及使用方法 |
| CA2854110C (en) * | 2011-11-02 | 2019-06-25 | Institut Pasteur De Lille | Effect of an attenuated bordetella strain against allergic disease |
| WO2014024026A1 (en) * | 2012-08-06 | 2014-02-13 | Glaxosmithkline Biologicals S.A. | Method for eliciting in infants an immune response against rsv and b. pertussis |
| EP2722338A1 (en) * | 2012-10-17 | 2014-04-23 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Novel recombinant Bordetella strains |
| US9655959B2 (en) * | 2014-10-01 | 2017-05-23 | National University Of Singapore | Adenylate cyclase deficient bordetella strains |
| CN109069535B (zh) * | 2016-03-29 | 2022-03-18 | 里尔巴斯德研究所 | 突变型博德特氏菌属菌株及其使用方法 |
| US10799573B2 (en) * | 2016-03-30 | 2020-10-13 | Regents Of The University Of Minnesota | Pertussis vaccines and methods of making and using |
| WO2018213361A1 (en) * | 2017-05-15 | 2018-11-22 | Vanderbilt University | LONG-CIRCULATING ZWITTERIONIC POLYPLEXES FOR siRNA DELIVERY |
| MX2020000441A (es) * | 2017-07-18 | 2020-08-17 | Serum Inst Of India Pvt Ltd | Una composicion inmunogenica que tiene estabilidad mejorada, inmunogeneicidad potenciada y reactogenicidad reducida y proceso para la preparacion de la misma. |
| CA3077428A1 (en) * | 2017-10-18 | 2019-04-25 | Institut Pasteur De Lille | Bordetella strains expressing serotype 3 fimbriae |
| US12036405B2 (en) * | 2018-03-23 | 2024-07-16 | The Board Of Regents Of The University Of Oklahoma | System and method of electric-induced acoustic tomography for electrotherapy monitoring |
| WO2020049133A1 (en) | 2018-09-05 | 2020-03-12 | National University Of Singapore | Adenylate cyclase catalytic domain deficient bordetella strains |
-
2018
- 2018-10-18 CA CA3077428A patent/CA3077428A1/en active Pending
- 2018-10-18 WO PCT/EP2018/078522 patent/WO2019077028A1/en not_active Ceased
- 2018-10-18 EP EP18815945.3A patent/EP3697439A1/en active Pending
- 2018-10-18 AU AU2018353409A patent/AU2018353409B2/en active Active
- 2018-10-18 SG SG11202003333WA patent/SG11202003333WA/en unknown
- 2018-10-18 JP JP2020520777A patent/JP7335874B2/ja active Active
- 2018-10-18 CN CN202411102248.9A patent/CN118979003A/zh active Pending
- 2018-10-18 CN CN201880067004.8A patent/CN111278456B/zh active Active
-
2020
- 2020-04-14 US US16/848,793 patent/US11446372B2/en active Active
-
2022
- 2022-08-03 US US17/817,272 patent/US12403188B2/en active Active
-
2023
- 2023-05-31 JP JP2023089684A patent/JP2023109996A/ja active Pending
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