JP2023098947A5 - - Google Patents

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Publication number
JP2023098947A5
JP2023098947A5 JP2023061595A JP2023061595A JP2023098947A5 JP 2023098947 A5 JP2023098947 A5 JP 2023098947A5 JP 2023061595 A JP2023061595 A JP 2023061595A JP 2023061595 A JP2023061595 A JP 2023061595A JP 2023098947 A5 JP2023098947 A5 JP 2023098947A5
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JP
Japan
Prior art keywords
use according
antagonist
composition
fibrosis
senescent cells
Prior art date
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Pending
Application number
JP2023061595A
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English (en)
Japanese (ja)
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JP2023098947A (ja
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Publication date
Priority claimed from EP17382417.8A external-priority patent/EP3421607A1/en
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Publication of JP2023098947A publication Critical patent/JP2023098947A/ja
Publication of JP2023098947A5 publication Critical patent/JP2023098947A5/ja
Pending legal-status Critical Current

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JP2023061595A 2017-06-29 2023-04-05 損傷および/または老化細胞の同定および排除 Pending JP2023098947A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP17382417.8 2017-06-29
EP17382417.8A EP3421607A1 (en) 2017-06-29 2017-06-29 Identification and elimination of damaged and/or senescent cells
JP2019572038A JP2020525021A (ja) 2017-06-29 2018-06-29 損傷および/または老化細胞の同定および排除

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
JP2019572038A Division JP2020525021A (ja) 2017-06-29 2018-06-29 損傷および/または老化細胞の同定および排除

Publications (2)

Publication Number Publication Date
JP2023098947A JP2023098947A (ja) 2023-07-11
JP2023098947A5 true JP2023098947A5 (https=) 2024-03-25

Family

ID=59315550

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2019572038A Pending JP2020525021A (ja) 2017-06-29 2018-06-29 損傷および/または老化細胞の同定および排除
JP2023061595A Pending JP2023098947A (ja) 2017-06-29 2023-04-05 損傷および/または老化細胞の同定および排除

Family Applications Before (1)

Application Number Title Priority Date Filing Date
JP2019572038A Pending JP2020525021A (ja) 2017-06-29 2018-06-29 損傷および/または老化細胞の同定および排除

Country Status (5)

Country Link
US (2) US20200123607A1 (https=)
EP (2) EP3421607A1 (https=)
JP (2) JP2020525021A (https=)
CA (1) CA3068363A1 (https=)
WO (1) WO2019002581A1 (https=)

Families Citing this family (19)

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Publication number Priority date Publication date Assignee Title
CN112996805A (zh) 2018-08-30 2021-06-18 Hcw生物科技公司 多链嵌合多肽和其用途
EP3843788A1 (en) 2018-08-30 2021-07-07 HCW Biologics, Inc. Single-chain chimeric polypeptides and uses thereof
JP7713393B2 (ja) 2019-06-21 2025-07-25 イミュニティーバイオ インコーポレイテッド 多鎖キメラポリペプチドおよびその使用
US12115191B2 (en) 2020-02-11 2024-10-15 Immunitybio, Inc. Methods of treating age-related and inflammatory diseases
KR20220140535A (ko) 2020-02-11 2022-10-18 에이치씨더블유 바이올로직스, 인크. 크로마토그래피 수지 및 이의 용도
EP4103599A1 (en) 2020-02-11 2022-12-21 HCW Biologics, Inc. Methods of activating regulatory t cells
EP4143231A1 (en) 2020-04-29 2023-03-08 HCW Biologics, Inc. Anti-cd26 proteins and uses thereof
US12024545B2 (en) * 2020-06-01 2024-07-02 HCW Biologics, Inc. Methods of treating aging-related disorders
EP4431102A4 (en) * 2021-11-10 2025-10-29 Lifeceutix Co Ltd Senescent Cell Elimination Compositions and Their Uses
CN114836508A (zh) * 2021-12-08 2022-08-02 上海锐翌医学检验实验室有限公司 慢性阻塞性肺病标志微生物及其应用
EP4486457A1 (en) 2022-03-04 2025-01-08 Rejuveron Senescence Therapeutics AG Anti pd-l2 antibody
EP4507711A1 (en) 2022-04-13 2025-02-19 ImmunityBio, Inc. Multi-chain chimeric polypeptide for use in the treatment of treating neuroinflammatory disorder
JPWO2023238845A1 (https=) * 2022-06-07 2023-12-14
CN115154611B (zh) * 2022-06-23 2023-11-17 中山大学孙逸仙纪念医院 免疫检查点抑制剂与抗衰老药物联合在制备肿瘤治疗产品中的用途
WO2024063109A1 (ja) * 2022-09-20 2024-03-28 国立大学法人東京大学 老化細胞除去剤
KR20260008114A (ko) * 2023-05-04 2026-01-15 (주)라이프신약 노화세포 제거 또는 억제용 조성물 및 이의 용도
WO2024249938A1 (en) * 2023-05-31 2024-12-05 Mayo Foundation For Medical Education And Research Methods and materials for identifying and treating senescence/age-related diseases
WO2025051889A1 (en) * 2023-09-06 2025-03-13 Rejuveron Senescence Therapeutics Ag Anti pd-l2 antibodies for use in treating fibrotic diseases
CN120960439A (zh) * 2025-10-14 2025-11-18 中南大学湘雅医院 Usp51的抑制剂与pd-l1/pd-1单抗药物联用在制备肿瘤免疫治疗药物中的应用

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8308235D0 (en) 1983-03-25 1983-05-05 Celltech Ltd Polypeptides
US5225539A (en) 1986-03-27 1993-07-06 Medical Research Council Recombinant altered antibodies and methods of making altered antibodies
WO1994004679A1 (en) 1991-06-14 1994-03-03 Genentech, Inc. Method for making humanized antibodies
AU2005248958A1 (en) * 2000-06-28 2006-02-02 Brigham And Women's Hospital PD-L2 molecules: novel PD-1 ligands and uses therefor
EP1320599A2 (en) * 2000-06-28 2003-06-25 Genetics Institute, LLC Pd-l2 molecules: pd-1 ligands and uses therefor
SG11201606428UA (en) * 2014-02-04 2016-09-29 Incyte Corp Combination of a pd-1 antagonist and an ido1 inhibitor for treating cancer
WO2016134416A1 (en) * 2015-02-23 2016-09-01 The University Of Queensland A method for assessing prognosis of lymphoma
JP2018515474A (ja) * 2015-04-28 2018-06-14 ブリストル−マイヤーズ スクイブ カンパニーBristol−Myers Squibb Company 抗pd−1抗体を使用するpd−l1陽性黒色腫の処置
RU2733033C2 (ru) * 2015-06-24 2020-09-28 Иммодьюлон Терапьютикс Лимитед Ингибитор контрольных точек и целые клетки микобактерий для применения в терапии рака
WO2017053250A1 (en) * 2015-09-21 2017-03-30 Merck Sharp & Dohme Corp. Antibody that binds to human programmed death ligand 2 (pd-l2) and uses thereof

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