JP2023060196A5 - - Google Patents

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Publication number
JP2023060196A5
JP2023060196A5 JP2023033777A JP2023033777A JP2023060196A5 JP 2023060196 A5 JP2023060196 A5 JP 2023060196A5 JP 2023033777 A JP2023033777 A JP 2023033777A JP 2023033777 A JP2023033777 A JP 2023033777A JP 2023060196 A5 JP2023060196 A5 JP 2023060196A5
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Japan
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composition
tic10
trail
agents
combination according
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JP2023033777A
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Japanese (ja)
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JP7600286B2 (ja
JP2023060196A (ja
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JP2023033777A 2011-04-29 2023-03-06 抗癌療法としての正常細胞および腫瘍細胞の小分子trail遺伝子誘導 Active JP7600286B2 (ja)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US201161480743P 2011-04-29 2011-04-29
US61/480,743 2011-04-29
JP2018210558A JP2019019145A (ja) 2011-04-29 2018-11-08 抗癌療法としての正常細胞および腫瘍細胞の小分子trail遺伝子誘導
JP2021151110A JP2021185210A (ja) 2011-04-29 2021-09-16 抗癌療法としての正常細胞および腫瘍細胞の小分子trail遺伝子誘導

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
JP2021151110A Division JP2021185210A (ja) 2011-04-29 2021-09-16 抗癌療法としての正常細胞および腫瘍細胞の小分子trail遺伝子誘導

Publications (3)

Publication Number Publication Date
JP2023060196A JP2023060196A (ja) 2023-04-27
JP2023060196A5 true JP2023060196A5 (enExample) 2023-05-24
JP7600286B2 JP7600286B2 (ja) 2024-12-16

Family

ID=47068061

Family Applications (7)

Application Number Title Priority Date Filing Date
JP2014508181A Active JP6132833B2 (ja) 2011-04-29 2012-04-30 抗癌療法としての正常細胞および腫瘍細胞の小分子trail遺伝子誘導
JP2016142086A Withdrawn JP2016199580A (ja) 2011-04-29 2016-07-20 抗癌療法としての正常細胞および腫瘍細胞の小分子trail遺伝子誘導
JP2018210558A Withdrawn JP2019019145A (ja) 2011-04-29 2018-11-08 抗癌療法としての正常細胞および腫瘍細胞の小分子trail遺伝子誘導
JP2021151110A Withdrawn JP2021185210A (ja) 2011-04-29 2021-09-16 抗癌療法としての正常細胞および腫瘍細胞の小分子trail遺伝子誘導
JP2023033777A Active JP7600286B2 (ja) 2011-04-29 2023-03-06 抗癌療法としての正常細胞および腫瘍細胞の小分子trail遺伝子誘導
JP2024027432A Pending JP2024051080A (ja) 2011-04-29 2024-02-27 抗癌療法としての正常細胞および腫瘍細胞の小分子trail遺伝子誘導
JP2025133453A Pending JP2025159099A (ja) 2011-04-29 2025-08-08 抗癌療法としての正常細胞および腫瘍細胞の小分子trail遺伝子誘導

Family Applications Before (4)

Application Number Title Priority Date Filing Date
JP2014508181A Active JP6132833B2 (ja) 2011-04-29 2012-04-30 抗癌療法としての正常細胞および腫瘍細胞の小分子trail遺伝子誘導
JP2016142086A Withdrawn JP2016199580A (ja) 2011-04-29 2016-07-20 抗癌療法としての正常細胞および腫瘍細胞の小分子trail遺伝子誘導
JP2018210558A Withdrawn JP2019019145A (ja) 2011-04-29 2018-11-08 抗癌療法としての正常細胞および腫瘍細胞の小分子trail遺伝子誘導
JP2021151110A Withdrawn JP2021185210A (ja) 2011-04-29 2021-09-16 抗癌療法としての正常細胞および腫瘍細胞の小分子trail遺伝子誘導

Family Applications After (2)

Application Number Title Priority Date Filing Date
JP2024027432A Pending JP2024051080A (ja) 2011-04-29 2024-02-27 抗癌療法としての正常細胞および腫瘍細胞の小分子trail遺伝子誘導
JP2025133453A Pending JP2025159099A (ja) 2011-04-29 2025-08-08 抗癌療法としての正常細胞および腫瘍細胞の小分子trail遺伝子誘導

Country Status (18)

Country Link
US (9) US8673923B2 (enExample)
EP (3) EP2701708B1 (enExample)
JP (7) JP6132833B2 (enExample)
CA (1) CA2832342C (enExample)
CY (1) CY1123010T1 (enExample)
DK (2) DK3679934T3 (enExample)
ES (2) ES2992934T3 (enExample)
FI (1) FI3679934T3 (enExample)
HR (2) HRP20241214T1 (enExample)
HU (2) HUE049207T2 (enExample)
LT (2) LT2701708T (enExample)
MX (2) MX365365B (enExample)
PL (2) PL2701708T3 (enExample)
PT (2) PT3679934T (enExample)
RS (2) RS60186B1 (enExample)
SI (2) SI2701708T1 (enExample)
SM (2) SMT202000272T1 (enExample)
WO (1) WO2012149546A2 (enExample)

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PT3679934T (pt) 2011-04-29 2024-09-05 Penn State Res Found Indução do gene trail de pequenas moléculas por células normais e tumorais enquanto terapia anticancro
US10314594B2 (en) 2012-12-14 2019-06-11 Corquest Medical, Inc. Assembly and method for left atrial appendage occlusion
US10813630B2 (en) 2011-08-09 2020-10-27 Corquest Medical, Inc. Closure system for atrial wall
US10307167B2 (en) 2012-12-14 2019-06-04 Corquest Medical, Inc. Assembly and method for left atrial appendage occlusion
US20140142689A1 (en) 2012-11-21 2014-05-22 Didier De Canniere Device and method of treating heart valve malfunction
WO2015073072A1 (en) * 2013-11-15 2015-05-21 Oncoceutics, Inc. 7-benzyl-4-(2-methylbenzyl)-2,4,6,7,8,9-hexahydroimidazo[1,2-a]pyrido[3,4-e]pyrimidin-5(1h)-one
BR112015023256A2 (pt) 2013-03-13 2017-07-18 Oncoceutics Inc terapia de combinação com 7-benzil-10-(2-metil-benzil)-2,6,7,8,9,10-hexaidroimidazol[1,2-a]pirido[4,3-d]pirimidin-5(3h)-ona.
US9688679B2 (en) 2013-03-13 2017-06-27 Oncoceutics, Inc. 7-benzyl-4-(methylbenzyl)-2,4,6,7,8,9-hexahydroimidazo[1,2-A]pyrido[3,4-E]pyrimidin-5 (1H)-one, salts thereof and methods of using the same in combination therapy
US9376437B2 (en) 2013-03-13 2016-06-28 Oncoceutics, Inc 7-benzyl-4-(2-methylbenzyl)-2,4,6,7,8,9-hexahydroimidazo[1,2-a]pyrido[3,4-e]pyrimidin-5(1H)-one, salts thereof and methods of using the same in combination therapy
CN106163524B (zh) * 2013-11-15 2019-11-08 昂克希尔迪克斯有限公司 7-苄基-4-(2-甲基苄基)-2,4,6,7,8,9-六氢咪唑并[1,2-a]吡啶并[3,4-e]嘧啶-5(1H)-酮、其盐及应用方法
US9566443B2 (en) 2013-11-26 2017-02-14 Corquest Medical, Inc. System for treating heart valve malfunction including mitral regurgitation
US11299528B2 (en) 2014-03-11 2022-04-12 D&D Pharmatech Inc. Long acting TRAIL receptor agonists for treatment of autoimmune diseases
SMT202400497T1 (it) 2014-03-31 2025-01-14 Scripps Research Inst Farmacoforo per induzione di trail
US10842626B2 (en) 2014-12-09 2020-11-24 Didier De Canniere Intracardiac device to correct mitral regurgitation
IL295286B2 (en) 2015-01-30 2024-10-01 Oncoceutics Inc 7-benzyl-4-(2-methylbenzyl)-2,4,6,7,8,9-hexahydroimidazo [1,2-a]pyrido[3,4-e]pyrimidin-5(1h)-one, analogs thereof, and salts thereof and methods for their use in therapy
CN107405428A (zh) 2015-03-31 2017-11-28 北卡罗来纳-查佩尔山大学 干细胞的递送载体及其用途
CN104860948B (zh) 2015-05-15 2017-09-26 南京盖特医药技术有限公司 咪唑并嘧啶酮类化合物及其制备方法和应用
WO2017106627A1 (en) 2015-12-17 2017-06-22 The Johns Hopkins University Ameliorating systemic sclerosis with death receptor agonists
EP3408298B1 (en) 2016-01-29 2024-11-20 Oncoceutics, Inc. G protein-coupled receptor (gpcr) modulation by imipridones
CN109195620B (zh) 2016-04-07 2022-06-28 约翰霍普金斯大学 用死亡受体激动剂治疗胰腺炎和疼痛的组合物和方法
US10172862B2 (en) 2017-01-30 2019-01-08 Oncoceutics, Inc. Imipridones for gliomas
US11767353B2 (en) 2020-06-05 2023-09-26 Theraly Fibrosis, Inc. Trail compositions with reduced immunogenicity
JP2025527300A (ja) 2022-08-05 2025-08-20 キメリックス インコーポレイテッド 神経膠腫の治療のための薬学的組成物及びその使用
WO2024102447A1 (en) * 2022-11-10 2024-05-16 Emory University Uses of hydroimidazopyridopyrimidinone derivatives for managing aneurysms or other vascular conditions or diseases

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WO2003055489A1 (en) * 2001-12-21 2003-07-10 Bayer Pharmaceuticals Corporation 2,4-diamino-pyrimidine derivative compounds as inhibitors of prolylpeptidase, inducers of apoptosis and cancer treatment agents
KR20080087822A (ko) * 2005-12-16 2008-10-01 제넨테크, 인크. 신경아교종을 진단하고, 예측하고, 치료하는 방법
JP5537035B2 (ja) * 2006-02-10 2014-07-02 ネルビアーノ・メデイカル・サイエンシーズ・エツセ・エルレ・エルレ Cdk阻害剤、および成長因子抗体または抗有糸分裂剤を含む組合せ
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PE20120559A1 (es) * 2009-06-24 2012-05-21 Stephen Evans-Freke Composicion que comprende al factor liberador de corticotropina
PT3679934T (pt) 2011-04-29 2024-09-05 Penn State Res Found Indução do gene trail de pequenas moléculas por células normais e tumorais enquanto terapia anticancro
BR112015023256A2 (pt) 2013-03-13 2017-07-18 Oncoceutics Inc terapia de combinação com 7-benzil-10-(2-metil-benzil)-2,6,7,8,9,10-hexaidroimidazol[1,2-a]pirido[4,3-d]pirimidin-5(3h)-ona.

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