JP2023040152A5 - - Google Patents

Download PDF

Info

Publication number
JP2023040152A5
JP2023040152A5 JP2023000651A JP2023000651A JP2023040152A5 JP 2023040152 A5 JP2023040152 A5 JP 2023040152A5 JP 2023000651 A JP2023000651 A JP 2023000651A JP 2023000651 A JP2023000651 A JP 2023000651A JP 2023040152 A5 JP2023040152 A5 JP 2023040152A5
Authority
JP
Japan
Prior art keywords
hours
primary
lymphocytes
contacting
viral vector
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2023000651A
Other languages
English (en)
Japanese (ja)
Other versions
JP2023040152A (ja
Filing date
Publication date
Priority claimed from JP2020141042A external-priority patent/JP2020191901A/ja
Application filed filed Critical
Publication of JP2023040152A publication Critical patent/JP2023040152A/ja
Publication of JP2023040152A5 publication Critical patent/JP2023040152A5/ja
Pending legal-status Critical Current

Links

JP2023000651A 2014-07-11 2023-01-05 Tリンパ球へのベクター導入効率の改善方法 Pending JP2023040152A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201462023618P 2014-07-11 2014-07-11
US62/023,618 2014-07-11
JP2020141042A JP2020191901A (ja) 2014-07-11 2020-08-24 Tリンパ球へのベクター導入効率の改善方法

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
JP2020141042A Division JP2020191901A (ja) 2014-07-11 2020-08-24 Tリンパ球へのベクター導入効率の改善方法

Publications (2)

Publication Number Publication Date
JP2023040152A JP2023040152A (ja) 2023-03-22
JP2023040152A5 true JP2023040152A5 (cg-RX-API-DMAC10.html) 2023-07-06

Family

ID=55064944

Family Applications (3)

Application Number Title Priority Date Filing Date
JP2017522459A Active JP6754761B2 (ja) 2014-07-11 2015-07-10 Tリンパ球へのベクター導入効率の改善方法
JP2020141042A Pending JP2020191901A (ja) 2014-07-11 2020-08-24 Tリンパ球へのベクター導入効率の改善方法
JP2023000651A Pending JP2023040152A (ja) 2014-07-11 2023-01-05 Tリンパ球へのベクター導入効率の改善方法

Family Applications Before (2)

Application Number Title Priority Date Filing Date
JP2017522459A Active JP6754761B2 (ja) 2014-07-11 2015-07-10 Tリンパ球へのベクター導入効率の改善方法
JP2020141042A Pending JP2020191901A (ja) 2014-07-11 2020-08-24 Tリンパ球へのベクター導入効率の改善方法

Country Status (5)

Country Link
US (2) US10982189B2 (cg-RX-API-DMAC10.html)
EP (2) EP3167058B1 (cg-RX-API-DMAC10.html)
JP (3) JP6754761B2 (cg-RX-API-DMAC10.html)
ES (2) ES2973524T3 (cg-RX-API-DMAC10.html)
WO (1) WO2016007827A1 (cg-RX-API-DMAC10.html)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US12590955B2 (en) 2013-03-15 2026-03-31 Zeon Corporation Methods and systems for processing particles
US20150064153A1 (en) 2013-03-15 2015-03-05 The Trustees Of Princeton University High efficiency microfluidic purification of stem cells to improve transplants
CN113512522A (zh) 2013-03-15 2021-10-19 普林斯顿大学理事会 用于高通量纯化的方法和设备
US11493428B2 (en) 2013-03-15 2022-11-08 Gpb Scientific, Inc. On-chip microfluidic processing of particles
US10982189B2 (en) 2014-07-11 2021-04-20 Celgene Corporation Methods of improving vector transduction efficiency into T lymphocytes
US10976232B2 (en) 2015-08-24 2021-04-13 Gpb Scientific, Inc. Methods and devices for multi-step cell purification and concentration
US10844353B2 (en) 2017-09-01 2020-11-24 Gpb Scientific, Inc. Methods for preparing therapeutically active cells using microfluidics
DE102018010282A1 (de) 2018-01-17 2019-07-18 Immatics US, Inc. Verfahren zur Feststellung der Wirksamkeit von viralen Vektoren
DE102018100967B4 (de) 2018-01-17 2019-08-14 Immatics US, Inc. Verfahren zur feststellung der wirksamkeit von viralen vektoren
CN108715865B (zh) * 2018-05-28 2021-09-21 福建师范大学 用于提高细胞转染效率的试剂组合物
US20220267726A1 (en) 2019-07-18 2022-08-25 Gpb Scientific, Inc. Ordered processing of blood products to produce therapeutically active cells
WO2021133897A1 (en) 2019-12-28 2021-07-01 Gpb Scientific, Inc. Microfluidic cartridges for processing particles and cells
CA3215429A1 (en) * 2021-04-06 2022-10-13 Unicet Biotech Co. Llc Methods to improve stability of virus transduction of .gamma..delta. t cells and applications thereof
WO2023286088A1 (en) * 2021-07-16 2023-01-19 Indian Institute Of Science Education And Research Bhopal Methods and compositions for viral vector transduction
WO2025180499A1 (zh) * 2024-02-28 2025-09-04 南京因领生物科技有限公司 一种提高细胞中病毒包装产量或质量的方法
CN119530302B (zh) * 2025-01-22 2025-06-27 青岛华赛伯曼医学细胞生物有限公司 提高til细胞的慢病毒转导效率及转导稳定性的方法及试剂盒

Family Cites Families (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6352694B1 (en) 1994-06-03 2002-03-05 Genetics Institute, Inc. Methods for inducing a population of T cells to proliferate using agents which recognize TCR/CD3 and ligands which stimulate an accessory molecule on the surface of the T cells
US6534055B1 (en) 1988-11-23 2003-03-18 Genetics Institute, Inc. Methods for selectively stimulating proliferation of T cells
US5665577A (en) 1989-02-06 1997-09-09 Dana-Farber Cancer Institute Vectors containing HIV packaging sequences, packaging defective HIV vectors, and uses thereof
IL104570A0 (en) 1992-03-18 1993-05-13 Yeda Res & Dev Chimeric genes and cells transformed therewith
US8211422B2 (en) 1992-03-18 2012-07-03 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Chimeric receptor genes and cells transformed therewith
US6692964B1 (en) 1995-05-04 2004-02-17 The United States Of America As Represented By The Secretary Of The Navy Methods for transfecting T cells
ATE292689T1 (de) * 1995-05-04 2005-04-15 Us Navy Verbesserte verfahren zur transfektion der t- zellen
US5948893A (en) 1996-01-17 1999-09-07 The United States Of America As Represented By The Secretary Of The Navy Murine hybridoma and antibody binding to CD28 receptor secreted by the hybridoma and method of using the antibody
US5994136A (en) 1997-12-12 1999-11-30 Cell Genesys, Inc. Method and means for producing high titer, safe, recombinant lentivirus vectors
ATE368122T1 (de) 1999-04-29 2007-08-15 Cell Genesys Inc Verfahren und mittel für die herstellung von sicheren rekombinanten lentiviralen vektoren mit hohem titer
AU2002251935B2 (en) 2001-02-14 2007-11-29 Celularity Inc. Post-partum mammalian placenta, its use and placental stem cells therefrom
US20060210536A1 (en) * 2003-04-17 2006-09-21 Curt Horvath Methods and compositions for inhibiting stat signaling pathways
DE602004030105D1 (de) * 2003-05-05 2010-12-30 Virxsys Corp Erhöhte transduktion mit abc-transportersubstratenhemmern
US20080311095A1 (en) 2007-05-23 2008-12-18 Sangamo Biosciences, Inc. Methods and compositions for increased transgene expression
EP2573185A3 (en) * 2005-02-16 2013-06-05 Lentigen Corporation Lentiviral vectors and their use
GB0526255D0 (en) * 2005-12-22 2006-02-01 Novartis Ag Organic compounds
KR20180105266A (ko) 2005-12-29 2018-09-27 안트로제네시스 코포레이션 태반 줄기 세포 집단
EP2203176B1 (en) 2007-09-28 2014-11-26 Anthrogenesis Corporation Tumor suppression using human placental perfusate and human placenta-derived intermediate natural killer cells
WO2010059828A1 (en) 2008-11-19 2010-05-27 Anthrogenesis Corporation Amnion derived adherent cells
MX342995B (es) 2010-07-13 2016-10-21 Anthrogenesis Corp Métodos de generar células asesinas naturales.
WO2012072096A1 (en) 2010-12-03 2012-06-07 Biontech Ag Method for cellular rna expression
EP3868888A1 (en) * 2012-02-29 2021-08-25 Helmholtz Zentrum München - Deutsches Forschungszentrum für Gesundheit und Umwelt (GmbH) Retroviral transduction using poloxamers
AU2013246443B2 (en) * 2012-04-11 2017-04-27 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Chimeric antigen receptors targeting B-cell maturation antigen
WO2014046617A1 (en) * 2012-09-19 2014-03-27 Agency For Science, Technology And Research Compositions and methods for treating cancer
US10982189B2 (en) 2014-07-11 2021-04-20 Celgene Corporation Methods of improving vector transduction efficiency into T lymphocytes

Similar Documents

Publication Publication Date Title
JP2020191901A5 (cg-RX-API-DMAC10.html)
JP6353953B2 (ja) 単一b細胞培養法
Barbacid et al. gag Gene of mammalian type-C RNA tumour viruses
US6340571B1 (en) Antibodies specific for Staphylococcus aureus, and use thereof
JP2013526286A5 (cg-RX-API-DMAC10.html)
WO1982001461A1 (en) Human hybridomas,precursors and products
CN105543170A (zh) 一种可刺激t细胞扩增的组合物
JP2017521101A5 (cg-RX-API-DMAC10.html)
JPH029366A (ja) モノクローナル二特異的免疫グロブリンを製造するためのファストトラック法
Borrebaeek et al. Human monoclonal antibodies produced from L-leucine methyl ester-treated and in vitro immunized peripheral blood lymphocytes
AU2019217363A1 (en) Closed-system manufacturing process for CAR-T cells
Dorfman The optimal technological approach to the development of human hybridomas
CN115819590B (zh) 抗猪红细胞膜抗体的制备及应用
JPS61271983A (ja) 腫瘍会合抗原に対するヒト脾細胞の生体外免疫処置法
GB2160544A (en) Monoclonal Antibody to HLI and its use for purifying HLI
JPH01168299A (ja) モノクローナル抗体およびそれを産生するハイブリドーマ
JP5435539B2 (ja) 抗体産生細胞の活性化ペプチド
CN111394387A (zh) 一种双特异性抗体细胞株的构建和筛选方法
JP5246859B2 (ja) 抗体産生細胞の誘導又は活性化方法
SU1527260A1 (ru) Штамм гибридных культивируемых клеток животных MUS мUSсULUS, используемый дл получени моноклональных антител к @ - тимозину
JP5164161B2 (ja) インビトロ免疫法
CN116063501A (zh) 一种抗cd4抗体及其用途
CN120757640A (zh) 一种球虫卵囊蛋白的单克隆抗体的制备方法
CN119751701A (zh) 一种抗cd117的嵌合抗原受体及其应用
CN114805589A (zh) 可同时识别牛、山羊、绵羊抗体的单克隆抗体