JP2023040152A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2023040152A5 JP2023040152A5 JP2023000651A JP2023000651A JP2023040152A5 JP 2023040152 A5 JP2023040152 A5 JP 2023040152A5 JP 2023000651 A JP2023000651 A JP 2023000651A JP 2023000651 A JP2023000651 A JP 2023000651A JP 2023040152 A5 JP2023040152 A5 JP 2023040152A5
- Authority
- JP
- Japan
- Prior art keywords
- hours
- primary
- lymphocytes
- contacting
- viral vector
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201462023618P | 2014-07-11 | 2014-07-11 | |
| US62/023,618 | 2014-07-11 | ||
| JP2020141042A JP2020191901A (ja) | 2014-07-11 | 2020-08-24 | Tリンパ球へのベクター導入効率の改善方法 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020141042A Division JP2020191901A (ja) | 2014-07-11 | 2020-08-24 | Tリンパ球へのベクター導入効率の改善方法 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2023040152A JP2023040152A (ja) | 2023-03-22 |
| JP2023040152A5 true JP2023040152A5 (cg-RX-API-DMAC10.html) | 2023-07-06 |
Family
ID=55064944
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017522459A Active JP6754761B2 (ja) | 2014-07-11 | 2015-07-10 | Tリンパ球へのベクター導入効率の改善方法 |
| JP2020141042A Pending JP2020191901A (ja) | 2014-07-11 | 2020-08-24 | Tリンパ球へのベクター導入効率の改善方法 |
| JP2023000651A Pending JP2023040152A (ja) | 2014-07-11 | 2023-01-05 | Tリンパ球へのベクター導入効率の改善方法 |
Family Applications Before (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017522459A Active JP6754761B2 (ja) | 2014-07-11 | 2015-07-10 | Tリンパ球へのベクター導入効率の改善方法 |
| JP2020141042A Pending JP2020191901A (ja) | 2014-07-11 | 2020-08-24 | Tリンパ球へのベクター導入効率の改善方法 |
Country Status (5)
| Country | Link |
|---|---|
| US (2) | US10982189B2 (cg-RX-API-DMAC10.html) |
| EP (2) | EP3167058B1 (cg-RX-API-DMAC10.html) |
| JP (3) | JP6754761B2 (cg-RX-API-DMAC10.html) |
| ES (2) | ES2973524T3 (cg-RX-API-DMAC10.html) |
| WO (1) | WO2016007827A1 (cg-RX-API-DMAC10.html) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US12590955B2 (en) | 2013-03-15 | 2026-03-31 | Zeon Corporation | Methods and systems for processing particles |
| US20150064153A1 (en) | 2013-03-15 | 2015-03-05 | The Trustees Of Princeton University | High efficiency microfluidic purification of stem cells to improve transplants |
| CN113512522A (zh) | 2013-03-15 | 2021-10-19 | 普林斯顿大学理事会 | 用于高通量纯化的方法和设备 |
| US11493428B2 (en) | 2013-03-15 | 2022-11-08 | Gpb Scientific, Inc. | On-chip microfluidic processing of particles |
| US10982189B2 (en) | 2014-07-11 | 2021-04-20 | Celgene Corporation | Methods of improving vector transduction efficiency into T lymphocytes |
| US10976232B2 (en) | 2015-08-24 | 2021-04-13 | Gpb Scientific, Inc. | Methods and devices for multi-step cell purification and concentration |
| US10844353B2 (en) | 2017-09-01 | 2020-11-24 | Gpb Scientific, Inc. | Methods for preparing therapeutically active cells using microfluidics |
| DE102018010282A1 (de) | 2018-01-17 | 2019-07-18 | Immatics US, Inc. | Verfahren zur Feststellung der Wirksamkeit von viralen Vektoren |
| DE102018100967B4 (de) | 2018-01-17 | 2019-08-14 | Immatics US, Inc. | Verfahren zur feststellung der wirksamkeit von viralen vektoren |
| CN108715865B (zh) * | 2018-05-28 | 2021-09-21 | 福建师范大学 | 用于提高细胞转染效率的试剂组合物 |
| US20220267726A1 (en) | 2019-07-18 | 2022-08-25 | Gpb Scientific, Inc. | Ordered processing of blood products to produce therapeutically active cells |
| WO2021133897A1 (en) | 2019-12-28 | 2021-07-01 | Gpb Scientific, Inc. | Microfluidic cartridges for processing particles and cells |
| CA3215429A1 (en) * | 2021-04-06 | 2022-10-13 | Unicet Biotech Co. Llc | Methods to improve stability of virus transduction of .gamma..delta. t cells and applications thereof |
| WO2023286088A1 (en) * | 2021-07-16 | 2023-01-19 | Indian Institute Of Science Education And Research Bhopal | Methods and compositions for viral vector transduction |
| WO2025180499A1 (zh) * | 2024-02-28 | 2025-09-04 | 南京因领生物科技有限公司 | 一种提高细胞中病毒包装产量或质量的方法 |
| CN119530302B (zh) * | 2025-01-22 | 2025-06-27 | 青岛华赛伯曼医学细胞生物有限公司 | 提高til细胞的慢病毒转导效率及转导稳定性的方法及试剂盒 |
Family Cites Families (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6352694B1 (en) | 1994-06-03 | 2002-03-05 | Genetics Institute, Inc. | Methods for inducing a population of T cells to proliferate using agents which recognize TCR/CD3 and ligands which stimulate an accessory molecule on the surface of the T cells |
| US6534055B1 (en) | 1988-11-23 | 2003-03-18 | Genetics Institute, Inc. | Methods for selectively stimulating proliferation of T cells |
| US5665577A (en) | 1989-02-06 | 1997-09-09 | Dana-Farber Cancer Institute | Vectors containing HIV packaging sequences, packaging defective HIV vectors, and uses thereof |
| IL104570A0 (en) | 1992-03-18 | 1993-05-13 | Yeda Res & Dev | Chimeric genes and cells transformed therewith |
| US8211422B2 (en) | 1992-03-18 | 2012-07-03 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Chimeric receptor genes and cells transformed therewith |
| US6692964B1 (en) | 1995-05-04 | 2004-02-17 | The United States Of America As Represented By The Secretary Of The Navy | Methods for transfecting T cells |
| ATE292689T1 (de) * | 1995-05-04 | 2005-04-15 | Us Navy | Verbesserte verfahren zur transfektion der t- zellen |
| US5948893A (en) | 1996-01-17 | 1999-09-07 | The United States Of America As Represented By The Secretary Of The Navy | Murine hybridoma and antibody binding to CD28 receptor secreted by the hybridoma and method of using the antibody |
| US5994136A (en) | 1997-12-12 | 1999-11-30 | Cell Genesys, Inc. | Method and means for producing high titer, safe, recombinant lentivirus vectors |
| ATE368122T1 (de) | 1999-04-29 | 2007-08-15 | Cell Genesys Inc | Verfahren und mittel für die herstellung von sicheren rekombinanten lentiviralen vektoren mit hohem titer |
| AU2002251935B2 (en) | 2001-02-14 | 2007-11-29 | Celularity Inc. | Post-partum mammalian placenta, its use and placental stem cells therefrom |
| US20060210536A1 (en) * | 2003-04-17 | 2006-09-21 | Curt Horvath | Methods and compositions for inhibiting stat signaling pathways |
| DE602004030105D1 (de) * | 2003-05-05 | 2010-12-30 | Virxsys Corp | Erhöhte transduktion mit abc-transportersubstratenhemmern |
| US20080311095A1 (en) | 2007-05-23 | 2008-12-18 | Sangamo Biosciences, Inc. | Methods and compositions for increased transgene expression |
| EP2573185A3 (en) * | 2005-02-16 | 2013-06-05 | Lentigen Corporation | Lentiviral vectors and their use |
| GB0526255D0 (en) * | 2005-12-22 | 2006-02-01 | Novartis Ag | Organic compounds |
| KR20180105266A (ko) | 2005-12-29 | 2018-09-27 | 안트로제네시스 코포레이션 | 태반 줄기 세포 집단 |
| EP2203176B1 (en) | 2007-09-28 | 2014-11-26 | Anthrogenesis Corporation | Tumor suppression using human placental perfusate and human placenta-derived intermediate natural killer cells |
| WO2010059828A1 (en) | 2008-11-19 | 2010-05-27 | Anthrogenesis Corporation | Amnion derived adherent cells |
| MX342995B (es) | 2010-07-13 | 2016-10-21 | Anthrogenesis Corp | Métodos de generar células asesinas naturales. |
| WO2012072096A1 (en) | 2010-12-03 | 2012-06-07 | Biontech Ag | Method for cellular rna expression |
| EP3868888A1 (en) * | 2012-02-29 | 2021-08-25 | Helmholtz Zentrum München - Deutsches Forschungszentrum für Gesundheit und Umwelt (GmbH) | Retroviral transduction using poloxamers |
| AU2013246443B2 (en) * | 2012-04-11 | 2017-04-27 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Chimeric antigen receptors targeting B-cell maturation antigen |
| WO2014046617A1 (en) * | 2012-09-19 | 2014-03-27 | Agency For Science, Technology And Research | Compositions and methods for treating cancer |
| US10982189B2 (en) | 2014-07-11 | 2021-04-20 | Celgene Corporation | Methods of improving vector transduction efficiency into T lymphocytes |
-
2015
- 2015-07-10 US US15/325,376 patent/US10982189B2/en active Active
- 2015-07-10 JP JP2017522459A patent/JP6754761B2/ja active Active
- 2015-07-10 EP EP15818898.7A patent/EP3167058B1/en active Active
- 2015-07-10 ES ES20176483T patent/ES2973524T3/es active Active
- 2015-07-10 EP EP20176483.4A patent/EP3750993B1/en active Active
- 2015-07-10 WO PCT/US2015/039892 patent/WO2016007827A1/en not_active Ceased
- 2015-07-10 ES ES15818898T patent/ES2813437T3/es active Active
-
2020
- 2020-08-24 JP JP2020141042A patent/JP2020191901A/ja active Pending
-
2021
- 2021-03-12 US US17/200,745 patent/US11629335B2/en active Active
-
2023
- 2023-01-05 JP JP2023000651A patent/JP2023040152A/ja active Pending
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2020191901A5 (cg-RX-API-DMAC10.html) | ||
| JP6353953B2 (ja) | 単一b細胞培養法 | |
| Barbacid et al. | gag Gene of mammalian type-C RNA tumour viruses | |
| US6340571B1 (en) | Antibodies specific for Staphylococcus aureus, and use thereof | |
| JP2013526286A5 (cg-RX-API-DMAC10.html) | ||
| WO1982001461A1 (en) | Human hybridomas,precursors and products | |
| CN105543170A (zh) | 一种可刺激t细胞扩增的组合物 | |
| JP2017521101A5 (cg-RX-API-DMAC10.html) | ||
| JPH029366A (ja) | モノクローナル二特異的免疫グロブリンを製造するためのファストトラック法 | |
| Borrebaeek et al. | Human monoclonal antibodies produced from L-leucine methyl ester-treated and in vitro immunized peripheral blood lymphocytes | |
| AU2019217363A1 (en) | Closed-system manufacturing process for CAR-T cells | |
| Dorfman | The optimal technological approach to the development of human hybridomas | |
| CN115819590B (zh) | 抗猪红细胞膜抗体的制备及应用 | |
| JPS61271983A (ja) | 腫瘍会合抗原に対するヒト脾細胞の生体外免疫処置法 | |
| GB2160544A (en) | Monoclonal Antibody to HLI and its use for purifying HLI | |
| JPH01168299A (ja) | モノクローナル抗体およびそれを産生するハイブリドーマ | |
| JP5435539B2 (ja) | 抗体産生細胞の活性化ペプチド | |
| CN111394387A (zh) | 一种双特异性抗体细胞株的构建和筛选方法 | |
| JP5246859B2 (ja) | 抗体産生細胞の誘導又は活性化方法 | |
| SU1527260A1 (ru) | Штамм гибридных культивируемых клеток животных MUS мUSсULUS, используемый дл получени моноклональных антител к @ - тимозину | |
| JP5164161B2 (ja) | インビトロ免疫法 | |
| CN116063501A (zh) | 一种抗cd4抗体及其用途 | |
| CN120757640A (zh) | 一种球虫卵囊蛋白的单克隆抗体的制备方法 | |
| CN119751701A (zh) | 一种抗cd117的嵌合抗原受体及其应用 | |
| CN114805589A (zh) | 可同时识别牛、山羊、绵羊抗体的单克隆抗体 |