JP2022553292A5 - - Google Patents

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Publication number
JP2022553292A5
JP2022553292A5 JP2022523383A JP2022523383A JP2022553292A5 JP 2022553292 A5 JP2022553292 A5 JP 2022553292A5 JP 2022523383 A JP2022523383 A JP 2022523383A JP 2022523383 A JP2022523383 A JP 2022523383A JP 2022553292 A5 JP2022553292 A5 JP 2022553292A5
Authority
JP
Japan
Prior art keywords
polynucleotide construct
binding domain
receptor
fragment
construct according
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2022523383A
Other languages
English (en)
Japanese (ja)
Other versions
JP2022553292A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2020/056723 external-priority patent/WO2021081133A1/en
Publication of JP2022553292A publication Critical patent/JP2022553292A/ja
Publication of JP2022553292A5 publication Critical patent/JP2022553292A5/ja
Pending legal-status Critical Current

Links

JP2022523383A 2019-10-21 2020-10-21 操作されたナチュラルキラー細胞、ならびに免疫療法およびオートファジー阻害技法においてそれを使用するための方法 Pending JP2022553292A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201962923644P 2019-10-21 2019-10-21
US62/923,644 2019-10-21
PCT/US2020/056723 WO2021081133A1 (en) 2019-10-21 2020-10-21 Engineered natural killer cells and methods for using the same in immunotherapy and autophagy inhibition techniques

Publications (2)

Publication Number Publication Date
JP2022553292A JP2022553292A (ja) 2022-12-22
JP2022553292A5 true JP2022553292A5 (enExample) 2024-01-04

Family

ID=75620220

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2022523383A Pending JP2022553292A (ja) 2019-10-21 2020-10-21 操作されたナチュラルキラー細胞、ならびに免疫療法およびオートファジー阻害技法においてそれを使用するための方法

Country Status (6)

Country Link
US (1) US20220362299A1 (enExample)
EP (1) EP4048292A4 (enExample)
JP (1) JP2022553292A (enExample)
AU (1) AU2020371628A1 (enExample)
CA (1) CA3155246A1 (enExample)
WO (1) WO2021081133A1 (enExample)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL303269A (en) 2020-12-03 2023-07-01 Century Therapeutics Inc Genetically engineered cells and uses thereof
US11661459B2 (en) 2020-12-03 2023-05-30 Century Therapeutics, Inc. Artificial cell death polypeptide for chimeric antigen receptor and uses thereof
TW202241935A (zh) 2020-12-18 2022-11-01 美商世紀治療股份有限公司 具有可調適受體專一性之嵌合抗原受體系統
CN113621073A (zh) * 2021-07-14 2021-11-09 上海易慕峰生物科技有限公司 一种新型嵌合受体组合物、重组载体、细胞及其应用
CN120459135B (zh) * 2025-07-16 2025-10-10 深圳市中佳生物医疗科技有限公司 Cd73+nk细胞在制备预防或治疗帕金森的药物中的应用

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1914242A1 (en) * 2006-10-19 2008-04-23 Sanofi-Aventis Novel anti-CD38 antibodies for the treatment of cancer
SG11201505858VA (en) * 2013-01-28 2015-09-29 St Jude Childrens Res Hospital A chimeric receptor with nkg2d specificity for use in cell therapy against cancer and infectious disease
GB201403972D0 (en) * 2014-03-06 2014-04-23 Ucl Business Plc Chimeric antigen receptor
EP3789403A1 (en) * 2014-11-11 2021-03-10 MedImmune Limited Therapeutic combinations comprising anti-cd73 antibodies and a2a receptor inhibitor and uses thereof
JP6805142B2 (ja) * 2014-11-21 2020-12-23 ブリストル−マイヤーズ スクイブ カンパニーBristol−Myers Squibb Company Cd73に対する抗体およびその使用
CN105384825B (zh) * 2015-08-11 2018-06-01 南京传奇生物科技有限公司 一种基于单域抗体的双特异性嵌合抗原受体及其应用
US20190112380A1 (en) 2016-03-29 2019-04-18 University Of Southern California Chimeric antigen receptors targeting cancer
CN118165113B (zh) * 2016-04-26 2025-10-28 恺兴生命科技(上海)有限公司 一种改善免疫应答细胞功能的方法
WO2018118494A2 (en) * 2016-12-22 2018-06-28 Xiaotong Song Use of car-modified human natural killer cells to treat cancer
AU2018269194B2 (en) * 2017-05-15 2025-05-22 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Bicistronic chimeric antigen receptors and their uses

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