JP2022551607A5 - - Google Patents
Info
- Publication number
- JP2022551607A5 JP2022551607A5 JP2022520570A JP2022520570A JP2022551607A5 JP 2022551607 A5 JP2022551607 A5 JP 2022551607A5 JP 2022520570 A JP2022520570 A JP 2022520570A JP 2022520570 A JP2022520570 A JP 2022520570A JP 2022551607 A5 JP2022551607 A5 JP 2022551607A5
- Authority
- JP
- Japan
Links
Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2025101880A JP7770607B2 (ja) | 2019-10-03 | 2025-06-18 | ヘテロタンデム二環式ペプチド複合体 |
| JP2025185492A JP2026027327A (ja) | 2019-10-03 | 2025-11-04 | ヘテロタンデム二環式ペプチド複合体 |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201962910129P | 2019-10-03 | 2019-10-03 | |
| US62/910,129 | 2019-10-03 | ||
| PCT/GB2020/052445 WO2021064428A1 (en) | 2019-10-03 | 2020-10-05 | Heterotandem bicyclic peptide complexes |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2025101880A Division JP7770607B2 (ja) | 2019-10-03 | 2025-06-18 | ヘテロタンデム二環式ペプチド複合体 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2022551607A JP2022551607A (ja) | 2022-12-12 |
| JPWO2021064428A5 JPWO2021064428A5 (https=) | 2023-10-10 |
| JP2022551607A5 true JP2022551607A5 (https=) | 2023-10-10 |
Family
ID=72811890
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022520570A Pending JP2022551607A (ja) | 2019-10-03 | 2020-10-05 | ヘテロタンデム二環式ペプチド複合体 |
| JP2025101880A Active JP7770607B2 (ja) | 2019-10-03 | 2025-06-18 | ヘテロタンデム二環式ペプチド複合体 |
| JP2025185492A Pending JP2026027327A (ja) | 2019-10-03 | 2025-11-04 | ヘテロタンデム二環式ペプチド複合体 |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2025101880A Active JP7770607B2 (ja) | 2019-10-03 | 2025-06-18 | ヘテロタンデム二環式ペプチド複合体 |
| JP2025185492A Pending JP2026027327A (ja) | 2019-10-03 | 2025-11-04 | ヘテロタンデム二環式ペプチド複合体 |
Country Status (16)
| Country | Link |
|---|---|
| US (2) | US11332500B2 (https=) |
| EP (3) | EP4592309A3 (https=) |
| JP (3) | JP2022551607A (https=) |
| CN (2) | CN119192401A (https=) |
| DK (1) | DK4464721T3 (https=) |
| ES (1) | ES3033517T3 (https=) |
| FI (1) | FI4464721T3 (https=) |
| HR (1) | HRP20250841T1 (https=) |
| HU (1) | HUE072242T2 (https=) |
| LT (1) | LT4464721T (https=) |
| PL (1) | PL4464721T3 (https=) |
| PT (1) | PT4464721T (https=) |
| RS (1) | RS67014B1 (https=) |
| SI (1) | SI4464721T1 (https=) |
| SM (1) | SMT202500247T1 (https=) |
| WO (1) | WO2021064428A1 (https=) |
Families Citing this family (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP6882978B2 (ja) | 2014-10-29 | 2021-06-02 | バイスクルアールディー・リミテッド | Ｍｔ１−ｍｍｐに特異的な二環性ペプチドリガンド |
| JP7301757B2 (ja) | 2017-06-26 | 2023-07-03 | バイスクルアールディー・リミテッド | 検出可能部分を持つ二環式ペプチドリガンドおよびその使用 |
| CN111183147B (zh) | 2017-08-04 | 2024-07-05 | 拜斯科技术开发有限公司 | Cd137特异性的双环肽配体 |
| GB201721265D0 (en) | 2017-12-19 | 2018-01-31 | Bicyclerd Ltd | Bicyclic peptide ligands specific for EphA2 |
| TWI825046B (zh) | 2017-12-19 | 2023-12-11 | 英商拜西可泰克斯有限公司 | Epha2特用之雙環胜肽配位基 |
| JP2021514953A (ja) | 2018-02-23 | 2021-06-17 | バイスクルテクス・リミテッド | 多量体二環式ペプチドリガンド |
| JP7551500B2 (ja) | 2018-04-04 | 2024-09-17 | バイスクルテクス・リミテッド | ヘテロタンデム二環式ペプチド複合体 |
| IL279489B2 (en) | 2018-06-22 | 2025-10-01 | Bicycletx Ltd | Bicyclic peptide ligands specific for nectin-4, a drug conjugate containing the peptide ligands and a pharmaceutical composition containing the drug conjugate |
| GB201810316D0 (en) | 2018-06-22 | 2018-08-08 | Bicyclerd Ltd | Peptide ligands for binding to EphA2 |
| GB201820288D0 (en) | 2018-12-13 | 2019-01-30 | Bicycle Tx Ltd | Bicycle peptide ligaands specific for MT1-MMP |
| GB201820325D0 (en) | 2018-12-13 | 2019-01-30 | Bicyclerd Ltd | Bicyclic peptide ligands specific for psma |
| GB201820295D0 (en) | 2018-12-13 | 2019-01-30 | Bicyclerd Ltd | Bicyclic peptide ligands specific for MT1-MMP |
| JP2022514618A (ja) | 2018-12-21 | 2022-02-14 | バイスクルテクス・リミテッド | Ｐｄ－ｌ１に特異的な二環式ペプチドリガンド |
| US12551567B2 (en) | 2018-12-21 | 2026-02-17 | Bicyclerd Limited | Bicyclic peptide ligands specific for PD-L1 |
| GB201900529D0 (en) | 2019-01-15 | 2019-03-06 | Bicycletx Ltd | Bicyclic peptide ligands specific for CD38 |
| KR20220007098A (ko) | 2019-05-09 | 2022-01-18 | 바이사이클티엑스 리미티드 | Ox40에 특이적인 이환식 펩티드 리간드 |
| TWI860386B (zh) | 2019-07-30 | 2024-11-01 | 英商拜西可泰克斯有限公司 | 異質雙環肽複合物 |
| ES3033517T3 (en) | 2019-10-03 | 2025-08-05 | Bicycletx Ltd | Heterotandem bicyclic peptide complexes |
| KR20220146543A (ko) | 2020-02-27 | 2022-11-01 | 본스인코오포레이티드 | 수정된 에지를 갖는 mov 관련 디바이스 및 방법 |
| IL300248A (en) | 2020-08-03 | 2023-03-01 | Bicycletx Ltd | peptide-based linkers |
| US20250186539A2 (en) * | 2021-01-11 | 2025-06-12 | Bicycletx Limited | Methods for treating cancer |
| CN118215672A (zh) * | 2021-06-01 | 2024-06-18 | 南京明德新药研发有限公司 | 多肽偶联药物及其应用 |
| EP4704904A1 (en) * | 2023-05-04 | 2026-03-11 | Tambo, Inc. | Tetrazine-based targeting agents for in vivo delivery of a payload |
| CN121532408A (zh) * | 2023-06-23 | 2026-02-13 | 拜斯科技术开发有限公司 | 对nk细胞具有特异性的双环肽配体 |
| WO2025191096A1 (en) * | 2024-03-14 | 2025-09-18 | Bicycletx Limited | Bicyclic peptide |
Family Cites Families (30)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4658014A (en) | 1985-12-20 | 1987-04-14 | Kempe Tomas G | Synthetic peptides with calcitonin-like activity |
| EP1452868A2 (en) | 2003-02-27 | 2004-09-01 | Pepscan Systems B.V. | Method for selecting a candidate drug compound |
| DK1844337T3 (da) | 2005-01-24 | 2013-09-30 | Pepscan Systems Bv | Bindingsforbindelser, immunogene forbindelser og peptidmimetika |
| JP5872751B2 (ja) * | 2006-02-06 | 2016-03-01 | バーナム インスティテュート フォー メディカル リサーチ | 腫瘍および損傷のターゲティングに関する方法および組成物 |
| AU2009211253B2 (en) * | 2008-02-05 | 2014-11-06 | Bicyclerd Limited | Methods and compositions |
| GB0913775D0 (en) | 2009-08-06 | 2009-09-16 | Medical Res Council | Multispecific peptides |
| US20130130985A1 (en) | 2010-04-01 | 2013-05-23 | Paul Alewood | Oxytocin peptide analogues |
| WO2012057624A1 (en) | 2010-10-25 | 2012-05-03 | Pepscan Systems B.V. | Novel bicyclic peptide mimetics |
| AU2012320407B2 (en) | 2011-10-07 | 2017-04-20 | Bicyclerd Limited | Modulation of structured polypeptide specificity |
| GB201306623D0 (en) | 2013-04-11 | 2013-05-29 | Bicycle Therapeutics Ltd | Modulation of structured polypeptide specificity |
| CN106794264B (zh) * | 2014-06-10 | 2021-03-23 | 3B制药有限公司 | 包含神经降压肽受体配体的缀合物及其用途 |
| JP6882978B2 (ja) | 2014-10-29 | 2021-06-02 | バイスクルアールディー・リミテッド | Ｍｔ１−ｍｍｐに特異的な二環性ペプチドリガンド |
| JP2019513371A (ja) | 2016-04-01 | 2019-05-30 | アビディティー バイオサイエンシーズ エルエルシー | 核酸ポリペプチド組成物とその使用 |
| AU2017252233A1 (en) * | 2016-04-22 | 2018-11-15 | Alligator Bioscience Ab | Novel bispecific polypeptides against CD137 |
| GB201607827D0 (en) | 2016-05-04 | 2016-06-15 | Bicycle Therapeutics Ltd | Bicyclic peptide-toxin conjugates specific for MT1-MMP |
| IL268836B2 (en) | 2017-02-24 | 2024-04-01 | Macrogenics Inc | Bispecific binding molecules that are capable of binding cd137 and tumor antigens, and uses thereof |
| CN111183147B (zh) | 2017-08-04 | 2024-07-05 | 拜斯科技术开发有限公司 | Cd137特异性的双环肽配体 |
| GB201721265D0 (en) | 2017-12-19 | 2018-01-31 | Bicyclerd Ltd | Bicyclic peptide ligands specific for EphA2 |
| TWI825046B (zh) | 2017-12-19 | 2023-12-11 | 英商拜西可泰克斯有限公司 | Epha2特用之雙環胜肽配位基 |
| JP2021514953A (ja) | 2018-02-23 | 2021-06-17 | バイスクルテクス・リミテッド | 多量体二環式ペプチドリガンド |
| JP7551500B2 (ja) | 2018-04-04 | 2024-09-17 | バイスクルテクス・リミテッド | ヘテロタンデム二環式ペプチド複合体 |
| GB201810316D0 (en) | 2018-06-22 | 2018-08-08 | Bicyclerd Ltd | Peptide ligands for binding to EphA2 |
| IL279489B2 (en) | 2018-06-22 | 2025-10-01 | Bicycletx Ltd | Bicyclic peptide ligands specific for nectin-4, a drug conjugate containing the peptide ligands and a pharmaceutical composition containing the drug conjugate |
| WO2020084305A1 (en) | 2018-10-23 | 2020-04-30 | Bicycletx Limited | Bicyclic peptide ligands and uses thereof |
| JP2022514618A (ja) | 2018-12-21 | 2022-02-14 | バイスクルテクス・リミテッド | Ｐｄ－ｌ１に特異的な二環式ペプチドリガンド |
| US20220184222A1 (en) | 2019-04-02 | 2022-06-16 | Bicycletx Limited | Bicycle toxin conjugates and uses thereof |
| KR20220007098A (ko) | 2019-05-09 | 2022-01-18 | 바이사이클티엑스 리미티드 | Ox40에 특이적인 이환식 펩티드 리간드 |
| TWI860386B (zh) * | 2019-07-30 | 2024-11-01 | 英商拜西可泰克斯有限公司 | 異質雙環肽複合物 |
| WO2021028686A1 (en) * | 2019-08-13 | 2021-02-18 | Bicycletx Limited | Modified multimeric bicyclic peptide ligands |
| ES3033517T3 (en) | 2019-10-03 | 2025-08-05 | Bicycletx Ltd | Heterotandem bicyclic peptide complexes |
-
2020
- 2020-10-05 ES ES24203287T patent/ES3033517T3/es active Active
- 2020-10-05 RS RS20250710A patent/RS67014B1/sr unknown
- 2020-10-05 HR HRP20250841TT patent/HRP20250841T1/hr unknown
- 2020-10-05 EP EP25175050.1A patent/EP4592309A3/en active Pending
- 2020-10-05 EP EP24203287.8A patent/EP4464721B1/en active Active
- 2020-10-05 LT LTEP24203287.8T patent/LT4464721T/lt unknown
- 2020-10-05 FI FIEP24203287.8T patent/FI4464721T3/fi active
- 2020-10-05 WO PCT/GB2020/052445 patent/WO2021064428A1/en not_active Ceased
- 2020-10-05 SM SM20250247T patent/SMT202500247T1/it unknown
- 2020-10-05 PL PL24203287.8T patent/PL4464721T3/pl unknown
- 2020-10-05 JP JP2022520570A patent/JP2022551607A/ja active Pending
- 2020-10-05 SI SI202030628T patent/SI4464721T1/sl unknown
- 2020-10-05 CN CN202411379106.7A patent/CN119192401A/zh active Pending
- 2020-10-05 PT PT242032878T patent/PT4464721T/pt unknown
- 2020-10-05 US US17/062,662 patent/US11332500B2/en active Active
- 2020-10-05 EP EP20789240.7A patent/EP4038096A1/en active Pending
- 2020-10-05 DK DK24203287.8T patent/DK4464721T3/da active
- 2020-10-05 CN CN202080069454.8A patent/CN114867753A/zh active Pending
- 2020-10-05 HU HUE24203287A patent/HUE072242T2/hu unknown
-
2022
- 2022-03-22 US US17/655,822 patent/US20220306694A1/en not_active Abandoned
-
2025
- 2025-06-18 JP JP2025101880A patent/JP7770607B2/ja active Active
- 2025-11-04 JP JP2025185492A patent/JP2026027327A/ja active Pending