JP2022549495A5 - - Google Patents

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Publication number
JP2022549495A5
JP2022549495A5 JP2022519147A JP2022519147A JP2022549495A5 JP 2022549495 A5 JP2022549495 A5 JP 2022549495A5 JP 2022519147 A JP2022519147 A JP 2022519147A JP 2022519147 A JP2022519147 A JP 2022519147A JP 2022549495 A5 JP2022549495 A5 JP 2022549495A5
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JP
Japan
Prior art keywords
antibody
drug conjugate
administered
composition according
dose
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JP2022519147A
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English (en)
Japanese (ja)
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JP2022549495A (ja
JP7659546B2 (ja
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Priority claimed from PCT/US2020/052674 external-priority patent/WO2021062122A1/en
Publication of JP2022549495A publication Critical patent/JP2022549495A/ja
Publication of JP2022549495A5 publication Critical patent/JP2022549495A5/ja
Application granted granted Critical
Publication of JP7659546B2 publication Critical patent/JP7659546B2/ja
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JP2022519147A 2019-09-25 2020-09-25 造血器がんの治療のための抗cd30 adc、抗pd-1、および化学療法剤の併用 Active JP7659546B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201962905701P 2019-09-25 2019-09-25
US62/905,701 2019-09-25
PCT/US2020/052674 WO2021062122A1 (en) 2019-09-25 2020-09-25 Combination anti-cd30 adc, anti-pd-1 and chemotherapeutic for treatment of hematopoietic cancers

Publications (3)

Publication Number Publication Date
JP2022549495A JP2022549495A (ja) 2022-11-25
JP2022549495A5 true JP2022549495A5 (enExample) 2023-10-03
JP7659546B2 JP7659546B2 (ja) 2025-04-09

Family

ID=72915898

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2022519147A Active JP7659546B2 (ja) 2019-09-25 2020-09-25 造血器がんの治療のための抗cd30 adc、抗pd-1、および化学療法剤の併用

Country Status (10)

Country Link
US (1) US20220347313A1 (enExample)
EP (1) EP4034154A1 (enExample)
JP (1) JP7659546B2 (enExample)
KR (1) KR20220069964A (enExample)
CN (1) CN114728046A (enExample)
AU (1) AU2020351751A1 (enExample)
CA (1) CA3155341A1 (enExample)
IL (1) IL291585A (enExample)
MX (1) MX2022003357A (enExample)
WO (1) WO2021062122A1 (enExample)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN117241802A (zh) * 2021-04-21 2023-12-15 新基公司 使用2-(2,6-二氧代哌啶-3-基)-4-((2-氟-4-((3-吗啉代氮杂环丁烷-1-基)甲基)苄基)氨基)异吲哚啉-1,3-二酮治疗非霍奇金淋巴瘤的方法

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US4925648A (en) 1988-07-29 1990-05-15 Immunomedics, Inc. Detection and treatment of infectious and inflammatory lesions
US5601819A (en) 1988-08-11 1997-02-11 The General Hospital Corporation Bispecific antibodies for selective immune regulation and for selective immune cell binding
EP0739904A1 (en) 1989-06-29 1996-10-30 Medarex, Inc. Bispecific reagents for aids therapy
EP1690935A3 (en) 1990-01-12 2008-07-30 Abgenix, Inc. Generation of xenogeneic antibodies
DK0553244T4 (da) 1990-10-05 2005-08-01 Celldex Therapeutics Inc Målrettet immunostimulering med bispecifikke reagenser
AU8727291A (en) 1990-10-29 1992-06-11 Cetus Oncology Corporation Bispecific antibodies, method of production, and uses thereof
EP0582595A1 (en) 1991-04-26 1994-02-16 Surface Active Limited Novel antibodies, and methods for their use
EP1306095A3 (en) 1992-03-05 2003-06-25 Board Of Regents, The University Of Texas System Methods and compositions for targeting the vasculature of solid tumors
ES2539411T3 (es) 1999-08-23 2015-06-30 Dana-Farber Cancer Institute, Inc. PD-1, receptor para la B7-4 y su utilización
US7090843B1 (en) 2000-11-28 2006-08-15 Seattle Genetics, Inc. Recombinant anti-CD30 antibodies and uses thereof
US6884869B2 (en) 2001-04-30 2005-04-26 Seattle Genetics, Inc. Pentapeptide compounds and uses related thereto
ES2369542T3 (es) 2002-07-31 2011-12-01 Seattle Genetics, Inc. Conjugados de auristatina y su uso para tratar cáncer, una enfermedad autoinmune o una enfermedad infecciosa.
ES2367430T3 (es) 2002-12-23 2011-11-03 Wyeth Llc Anticuerpos contra pd-1 y sus usos.
US7837980B2 (en) 2004-03-02 2010-11-23 Seattle Genetics, Inc. Partially loaded antibodies and methods of their conjugation
EP3530736A3 (en) 2005-05-09 2019-11-06 ONO Pharmaceutical Co., Ltd. Human monoclonal antibodies to programmed death 1 (pd-1) and methods for treating cancer using anti-pd-1 antibodies alone or in combination with other immunotherapeutics
PT2170959E (pt) 2007-06-18 2014-01-07 Merck Sharp & Dohme Anticorpos para o receptor humano de morte programada pd-1
US8168757B2 (en) 2008-03-12 2012-05-01 Merck Sharp & Dohme Corp. PD-1 binding proteins
EA201500417A1 (ru) 2008-08-25 2015-11-30 Эмплиммьюн, Инк. Композиции антагонистов pd-1 и способы применения
WO2010081004A1 (en) 2009-01-09 2010-07-15 Seattle Genetics, Inc. Weekly dosing regimens for anti-cd30 vc-pab-mmae antibody drug-conjugates
CA2833636A1 (en) 2011-04-20 2012-10-26 Amplimmune, Inc. Antibodies and other molecules that bind b7-h1 and pd-1
RS61400B1 (sr) 2013-05-02 2021-02-26 Anaptysbio Inc Antitela usmerena protiv programirane smrti-1 (pd-1)
CA3175360C (en) 2013-05-31 2024-05-28 Sorrento Therapeutics, Inc. Antigen binding proteins that bind pd-1
SMT202300039T1 (it) 2013-09-13 2023-03-17 Beigene Switzerland Gmbh Anticorpi anti-pd1 e loro uso come terapia e per diagnostica
CR20160319A (es) 2013-12-12 2016-11-08 Jiangsu Hengrui Medicine Co Anticuerpo pd-1, fragmento de union al antigeno de este y uso médico de este
TWI681969B (zh) 2014-01-23 2020-01-11 美商再生元醫藥公司 針對pd-1的人類抗體
UA122479C2 (uk) 2014-01-24 2020-11-25 Дана-Фарбер Кенсер Інстітьют, Інк. Виділена молекула антитіла, яка зв’язується з людським білком програмованої смерті-1 (pd-1)
CA2937561A1 (en) * 2014-01-29 2015-08-06 Shanghai Hengrui Pharmaceutical Co., Ltd. Ligand-cytotoxic drug conjugate, preparation method thereof, and uses thereof
MX390955B (es) 2016-06-02 2025-03-19 Seagen Inc Uso de un anticuerpo anti-pd-1 en combinación con un anticuerpo anti-cd30 para el tratamiento de linfoma.

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