JP2022547080A - 超長鎖多価不飽和脂肪酸であるエロバノイドヒドロキシル化誘導体、および使用方法 - Google Patents
超長鎖多価不飽和脂肪酸であるエロバノイドヒドロキシル化誘導体、および使用方法 Download PDFInfo
- Publication number
- JP2022547080A JP2022547080A JP2022514679A JP2022514679A JP2022547080A JP 2022547080 A JP2022547080 A JP 2022547080A JP 2022514679 A JP2022514679 A JP 2022514679A JP 2022514679 A JP2022514679 A JP 2022514679A JP 2022547080 A JP2022547080 A JP 2022547080A
- Authority
- JP
- Japan
- Prior art keywords
- elv
- vlc
- carbon
- cells
- erovanoids
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Images
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
- A61K31/202—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids having three or more double bonds, e.g. linolenic
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/191—Carboxylic acids, e.g. valproic acid having two or more hydroxy groups, e.g. gluconic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Hospice & Palliative Care (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Immunology (AREA)
- Psychiatry (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2025111395A JP2025143368A (ja) | 2019-09-04 | 2025-07-01 | 超長鎖多価不飽和脂肪酸であるエロバノイドヒドロキシル化誘導体、および使用方法 |
Applications Claiming Priority (9)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201962895737P | 2019-09-04 | 2019-09-04 | |
| US62/895,737 | 2019-09-04 | ||
| US201962923770P | 2019-10-21 | 2019-10-21 | |
| US62/923,770 | 2019-10-21 | ||
| US201962924359P | 2019-10-22 | 2019-10-22 | |
| US62/924,359 | 2019-10-22 | ||
| US202062964995P | 2020-01-23 | 2020-01-23 | |
| US62/964,995 | 2020-01-23 | ||
| PCT/US2020/049541 WO2021046448A1 (en) | 2019-09-04 | 2020-09-04 | Very-long-chain polyunsaturated fatty acids, elovanoid hydroxylated derivatives, and methods of use |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2025111395A Division JP2025143368A (ja) | 2019-09-04 | 2025-07-01 | 超長鎖多価不飽和脂肪酸であるエロバノイドヒドロキシル化誘導体、および使用方法 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2022547080A true JP2022547080A (ja) | 2022-11-10 |
| JP2022547080A5 JP2022547080A5 (enExample) | 2024-04-02 |
Family
ID=74853054
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022514679A Pending JP2022547080A (ja) | 2019-09-04 | 2020-09-04 | 超長鎖多価不飽和脂肪酸であるエロバノイドヒドロキシル化誘導体、および使用方法 |
| JP2025111395A Pending JP2025143368A (ja) | 2019-09-04 | 2025-07-01 | 超長鎖多価不飽和脂肪酸であるエロバノイドヒドロキシル化誘導体、および使用方法 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2025111395A Pending JP2025143368A (ja) | 2019-09-04 | 2025-07-01 | 超長鎖多価不飽和脂肪酸であるエロバノイドヒドロキシル化誘導体、および使用方法 |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US20220339134A1 (enExample) |
| EP (1) | EP4025201A4 (enExample) |
| JP (2) | JP2022547080A (enExample) |
| CN (1) | CN114650814A (enExample) |
| AU (1) | AU2020343029A1 (enExample) |
| BR (1) | BR112022003985A2 (enExample) |
| CA (1) | CA3153088A1 (enExample) |
| MX (1) | MX2022002687A (enExample) |
| WO (1) | WO2021046448A1 (enExample) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2022056311A1 (en) * | 2020-09-10 | 2022-03-17 | Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College | Very-long-chain polyunsaturated fatty acids, elovanoid hydroxylated derivatives, and methods of use |
| CN118524834A (zh) * | 2021-12-03 | 2024-08-20 | 株式会社日水 | 氧化应激缓和方法 |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2018175288A1 (en) * | 2017-03-20 | 2018-09-27 | Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College | Very-long-chain polyunsaturated fatty acids, elovanoid hydroxylated derivatives, and methods of use |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2010037180A1 (en) * | 2008-10-03 | 2010-04-08 | Glycan Biosciences Pty Ltd | Anionic oligosaccharide conjugates |
| US20130190399A1 (en) * | 2009-10-31 | 2013-07-25 | Martek Biosciences Corporation | Synthesis and use of omega-3 and omega 6 very long chain polyunsaturated fatty acids (VLC-PUFA) |
| WO2016130522A1 (en) * | 2015-02-09 | 2016-08-18 | Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College | Compounds, compositions, and methods for the treatment of inflammatory, degenerative, and neurodegenerative diseases |
| US20170014365A1 (en) * | 2015-07-14 | 2017-01-19 | The Board Of Regents Of The University Of Oklahoma | Compositions Containing Very Long Chain Saturated Fatty Acids and Methods of Use |
| WO2017077528A2 (en) * | 2015-11-02 | 2017-05-11 | Salzman Lovelace Investments, Ltd. | Methods and pharmaceutical compositions for treatment of lung inflammation |
| US20220226270A1 (en) * | 2019-04-04 | 2022-07-21 | Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College | Very-long-chain polyunsaturated fatty acids, elovanoid hydroxylated derivatives, and methods of use |
-
2020
- 2020-09-04 WO PCT/US2020/049541 patent/WO2021046448A1/en not_active Ceased
- 2020-09-04 AU AU2020343029A patent/AU2020343029A1/en not_active Abandoned
- 2020-09-04 JP JP2022514679A patent/JP2022547080A/ja active Pending
- 2020-09-04 BR BR112022003985A patent/BR112022003985A2/pt unknown
- 2020-09-04 US US17/639,757 patent/US20220339134A1/en active Pending
- 2020-09-04 MX MX2022002687A patent/MX2022002687A/es unknown
- 2020-09-04 CN CN202080072552.7A patent/CN114650814A/zh active Pending
- 2020-09-04 CA CA3153088A patent/CA3153088A1/en active Pending
- 2020-09-04 EP EP20860080.9A patent/EP4025201A4/en not_active Withdrawn
-
2025
- 2025-07-01 JP JP2025111395A patent/JP2025143368A/ja active Pending
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2018175288A1 (en) * | 2017-03-20 | 2018-09-27 | Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College | Very-long-chain polyunsaturated fatty acids, elovanoid hydroxylated derivatives, and methods of use |
Non-Patent Citations (1)
| Title |
|---|
| 黒田悦史他: "「微細粒子による免疫系の活性化とアレルギー性炎症」", 日衛誌(JPN. J. HYG.), vol. 72, JPN6024030038, 2017, pages 27 - 31, ISSN: 0005539558 * |
Also Published As
| Publication number | Publication date |
|---|---|
| JP2025143368A (ja) | 2025-10-01 |
| MX2022002687A (es) | 2022-06-16 |
| CN114650814A (zh) | 2022-06-21 |
| EP4025201A4 (en) | 2023-08-30 |
| BR112022003985A2 (pt) | 2022-05-24 |
| EP4025201A1 (en) | 2022-07-13 |
| US20220339134A1 (en) | 2022-10-27 |
| CA3153088A1 (en) | 2021-03-11 |
| WO2021046448A1 (en) | 2021-03-11 |
| AU2020343029A1 (en) | 2022-03-31 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2025143368A (ja) | 超長鎖多価不飽和脂肪酸であるエロバノイドヒドロキシル化誘導体、および使用方法 | |
| CA3000985C (en) | Method for treating neurodegenerative diseases | |
| JP2019511495A (ja) | GSK3β阻害薬チデグルシブによるCDKL5障害の治療 | |
| WO2013070879A1 (en) | Methods for treating spinal cord injury with lpa receptor antagonists | |
| EP3253387A1 (en) | Compounds and uses in treatment of senescence-associated conditons | |
| JP2020514391A (ja) | 超長鎖多価不飽和脂肪酸、エロバノイドヒドロキシル化誘導体、および使用方法 | |
| US9956202B2 (en) | Use of indolyl and indolinyl hydroxamates for treating neurodegenerative disorders or cognitive decicits | |
| Park et al. | Suppressive effects of britanin, a sesquiterpene compound isolated from Inulae flos, on mast cell-mediated inflammatory responses | |
| JP7850416B2 (ja) | 細胞外小胞に含まれるenamptの産生および使用 | |
| WO2017135753A1 (ko) | 혈관내피성장인자를 과발현한 줄기세포를 유효성분으로 포함하는 퇴행성 신경질환의 예방 또는 치료용 약학적 조성물 | |
| JP2017128578A (ja) | 腎疾患の治療におけるモノおよびジカルボン酸のアミドの使用 | |
| AU2021283886A1 (en) | Dihomo-gamma linolenic acid (DGLA) is a novel senolytic | |
| US20240075004A1 (en) | Very-long-chain polyunsaturated fatty acids, elovanoid hydroxylated derivatives, and methods of use | |
| JP6928450B2 (ja) | エンドセリンb受容体アゴニストを用いた、神経精神疾患を治療するための組成物及び方法 | |
| AU2025220850A1 (en) | Compositions for regulating homeostasis of cortisol and improving sleep quality and methods of use and production thereof | |
| US9950036B2 (en) | Treatment of mood and stress related disorders | |
| JP5788907B2 (ja) | 疾患の治療に使用される化合物 | |
| JP2019530741A (ja) | 神経保護及び神経疾患におけるcgrp受容体アンタゴニストの使用 | |
| US11925642B2 (en) | Regulation of eIF4E activity for migraine therapy | |
| JP2023541886A (ja) | 超長鎖多価不飽和脂肪酸、エロバノイドヒドロキシル化誘導体、及び使用方法 | |
| US20240390377A1 (en) | Composition for the prevention or treatment of neurodegenerative or motor neuron diseases comprising halofuginone as an active ingredient | |
| KR101478304B1 (ko) | 신경염증 질환의 예방 또는 치료용 약학 조성물 | |
| CN118593706A (zh) | 通过调节Endoglin治疗痴呆的方法 | |
| WO2022217035A1 (en) | Activators of integrated stress response pathway for protection against ferroptosis | |
| JP7249433B2 (ja) | 蜂毒抽出物を有効成分として含有する神経炎症疾患の予防または治療用組成物 |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| A521 | Request for written amendment filed |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20220601 |
|
| A521 | Request for written amendment filed |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20220907 |
|
| RD04 | Notification of resignation of power of attorney |
Free format text: JAPANESE INTERMEDIATE CODE: A7424 Effective date: 20230720 |
|
| A521 | Request for written amendment filed |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20230901 |
|
| A621 | Written request for application examination |
Free format text: JAPANESE INTERMEDIATE CODE: A621 Effective date: 20230901 |
|
| A521 | Request for written amendment filed |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20240319 |
|
| A131 | Notification of reasons for refusal |
Free format text: JAPANESE INTERMEDIATE CODE: A131 Effective date: 20240801 |
|
| A601 | Written request for extension of time |
Free format text: JAPANESE INTERMEDIATE CODE: A601 Effective date: 20241030 |
|
| A02 | Decision of refusal |
Free format text: JAPANESE INTERMEDIATE CODE: A02 Effective date: 20250303 |