JP2022547080A - 超長鎖多価不飽和脂肪酸であるエロバノイドヒドロキシル化誘導体、および使用方法 - Google Patents

超長鎖多価不飽和脂肪酸であるエロバノイドヒドロキシル化誘導体、および使用方法 Download PDF

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JP2022547080A
JP2022547080A JP2022514679A JP2022514679A JP2022547080A JP 2022547080 A JP2022547080 A JP 2022547080A JP 2022514679 A JP2022514679 A JP 2022514679A JP 2022514679 A JP2022514679 A JP 2022514679A JP 2022547080 A JP2022547080 A JP 2022547080A
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elv
vlc
carbon
cells
erovanoids
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JP2022547080A5 (enExample
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リカルド パラシオス ペレーズ
ニコラス ジー. バザン
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
    • A61K31/202—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids having three or more double bonds, e.g. linolenic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/191—Carboxylic acids, e.g. valproic acid having two or more hydroxy groups, e.g. gluconic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Hospice & Palliative Care (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Immunology (AREA)
  • Psychiatry (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
JP2022514679A 2019-09-04 2020-09-04 超長鎖多価不飽和脂肪酸であるエロバノイドヒドロキシル化誘導体、および使用方法 Pending JP2022547080A (ja)

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JP2025111395A JP2025143368A (ja) 2019-09-04 2025-07-01 超長鎖多価不飽和脂肪酸であるエロバノイドヒドロキシル化誘導体、および使用方法

Applications Claiming Priority (9)

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US201962895737P 2019-09-04 2019-09-04
US62/895,737 2019-09-04
US201962923770P 2019-10-21 2019-10-21
US62/923,770 2019-10-21
US201962924359P 2019-10-22 2019-10-22
US62/924,359 2019-10-22
US202062964995P 2020-01-23 2020-01-23
US62/964,995 2020-01-23
PCT/US2020/049541 WO2021046448A1 (en) 2019-09-04 2020-09-04 Very-long-chain polyunsaturated fatty acids, elovanoid hydroxylated derivatives, and methods of use

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JP2022547080A5 JP2022547080A5 (enExample) 2024-04-02

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JP2025111395A Pending JP2025143368A (ja) 2019-09-04 2025-07-01 超長鎖多価不飽和脂肪酸であるエロバノイドヒドロキシル化誘導体、および使用方法

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US (1) US20220339134A1 (enExample)
EP (1) EP4025201A4 (enExample)
JP (2) JP2022547080A (enExample)
CN (1) CN114650814A (enExample)
AU (1) AU2020343029A1 (enExample)
BR (1) BR112022003985A2 (enExample)
CA (1) CA3153088A1 (enExample)
MX (1) MX2022002687A (enExample)
WO (1) WO2021046448A1 (enExample)

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Publication number Priority date Publication date Assignee Title
WO2022056311A1 (en) * 2020-09-10 2022-03-17 Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College Very-long-chain polyunsaturated fatty acids, elovanoid hydroxylated derivatives, and methods of use
CN118524834A (zh) * 2021-12-03 2024-08-20 株式会社日水 氧化应激缓和方法

Citations (1)

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Publication number Priority date Publication date Assignee Title
WO2018175288A1 (en) * 2017-03-20 2018-09-27 Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College Very-long-chain polyunsaturated fatty acids, elovanoid hydroxylated derivatives, and methods of use

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WO2010037180A1 (en) * 2008-10-03 2010-04-08 Glycan Biosciences Pty Ltd Anionic oligosaccharide conjugates
US20130190399A1 (en) * 2009-10-31 2013-07-25 Martek Biosciences Corporation Synthesis and use of omega-3 and omega 6 very long chain polyunsaturated fatty acids (VLC-PUFA)
WO2016130522A1 (en) * 2015-02-09 2016-08-18 Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College Compounds, compositions, and methods for the treatment of inflammatory, degenerative, and neurodegenerative diseases
US20170014365A1 (en) * 2015-07-14 2017-01-19 The Board Of Regents Of The University Of Oklahoma Compositions Containing Very Long Chain Saturated Fatty Acids and Methods of Use
WO2017077528A2 (en) * 2015-11-02 2017-05-11 Salzman Lovelace Investments, Ltd. Methods and pharmaceutical compositions for treatment of lung inflammation
US20220226270A1 (en) * 2019-04-04 2022-07-21 Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College Very-long-chain polyunsaturated fatty acids, elovanoid hydroxylated derivatives, and methods of use

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2018175288A1 (en) * 2017-03-20 2018-09-27 Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College Very-long-chain polyunsaturated fatty acids, elovanoid hydroxylated derivatives, and methods of use

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
黒田悦史他: "「微細粒子による免疫系の活性化とアレルギー性炎症」", 日衛誌(JPN. J. HYG.), vol. 72, JPN6024030038, 2017, pages 27 - 31, ISSN: 0005539558 *

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JP2025143368A (ja) 2025-10-01
MX2022002687A (es) 2022-06-16
CN114650814A (zh) 2022-06-21
EP4025201A4 (en) 2023-08-30
BR112022003985A2 (pt) 2022-05-24
EP4025201A1 (en) 2022-07-13
US20220339134A1 (en) 2022-10-27
CA3153088A1 (en) 2021-03-11
WO2021046448A1 (en) 2021-03-11
AU2020343029A1 (en) 2022-03-31

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