JP2022545967A5 - - Google Patents
Info
- Publication number
- JP2022545967A5 JP2022545967A5 JP2022513859A JP2022513859A JP2022545967A5 JP 2022545967 A5 JP2022545967 A5 JP 2022545967A5 JP 2022513859 A JP2022513859 A JP 2022513859A JP 2022513859 A JP2022513859 A JP 2022513859A JP 2022545967 A5 JP2022545967 A5 JP 2022545967A5
- Authority
- JP
- Japan
- Prior art keywords
- expression vector
- pharmaceutical composition
- composition according
- seq
- cells
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201962891799P | 2019-08-26 | 2019-08-26 | |
| US62/891,799 | 2019-08-26 | ||
| US201962902352P | 2019-09-18 | 2019-09-18 | |
| US62/902,352 | 2019-09-18 | ||
| US202063004258P | 2020-04-02 | 2020-04-02 | |
| US63/004,258 | 2020-04-02 | ||
| PCT/US2020/047733 WO2021041373A1 (en) | 2019-08-26 | 2020-08-25 | Treatment of diabetic retinopathy with fully-human post-translationally modified anti-vegf fab |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2022545967A JP2022545967A (ja) | 2022-11-01 |
| JP2022545967A5 true JP2022545967A5 (https=) | 2023-09-01 |
Family
ID=72473961
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022513859A Pending JP2022545967A (ja) | 2019-08-26 | 2020-08-25 | 完全ヒト翻訳後修飾抗ＶＥＧＦ Ｆａｂを用いる糖尿病性網膜症の処置 |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US20220280608A1 (https=) |
| EP (1) | EP4021936A1 (https=) |
| JP (1) | JP2022545967A (https=) |
| KR (1) | KR20220051246A (https=) |
| CN (1) | CN114502197A (https=) |
| AU (1) | AU2020336314A1 (https=) |
| BR (1) | BR112022003811A2 (https=) |
| CA (1) | CA3149401A1 (https=) |
| IL (1) | IL290863A (https=) |
| MX (1) | MX2022002366A (https=) |
| WO (1) | WO2021041373A1 (https=) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3727468A4 (en) | 2017-12-19 | 2021-09-22 | Akouos, Inc. | AAV-MEDIATED THERAPEUTIC ANTIBODIES DELIVERY TO THE INTERNAL EAR |
| EP3886946A1 (en) | 2019-06-05 | 2021-10-06 | Regeneron Pharmaceuticals, Inc. | Devices and methods for precision dose delivery |
| IL303317A (en) | 2020-12-01 | 2023-07-01 | Akouos Inc | ANTI-NATURAL ANTIBODY STRUCTURES AND RELATED METHODS FOR THE TREATMENT OF SYMPTOMS ASSOCIATED WITH VESTIBULAR SWANNOMA |
| IL319873A (en) | 2022-09-30 | 2025-05-01 | Regenxbio Inc | Treatment of eye diseases with recombinant viral vectors containing anti-VEGF FAB |
| USD1120314S1 (en) | 2022-11-30 | 2026-03-24 | Regeneron Pharmaceuticals, Inc. | Dose delivery device |
| WO2024178225A1 (en) * | 2023-02-22 | 2024-08-29 | Cornell University | Gene therapy mediated angiogenesis to enhance survival of transplanted fat |
| WO2025081143A1 (en) * | 2023-10-14 | 2025-04-17 | City Labs, Inc. | Radioluminescent eye device for modulation of photoreceptor metabolism |
Family Cites Families (36)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0804561B1 (en) | 1993-02-12 | 2009-12-30 | The Board Of Trustees Of The Leland Stanford Junior University | Regulated transcription of targeted genes and other biological events |
| AU719001B2 (en) | 1994-12-29 | 2000-05-04 | Massachusetts Institute Of Technology | Chimeric DNA-binding proteins |
| WO1996041865A1 (en) | 1995-06-07 | 1996-12-27 | Ariad Gene Therapeutics, Inc. | Rapamcycin-based regulation of biological events |
| JP2003524368A (ja) | 1997-08-26 | 2003-08-19 | アリアド ジーン セラピューティクス インコーポレイテッド | ニ量化ドメイン、三量化ドメインまたは四量化ドメインおよび補足的非相同転写活性化ドメイン、転写抑制ドメイン、ｄｎａ結合ドメインまたはリガンド結合ドメインを含む融合蛋白 |
| JP2001514007A (ja) | 1997-08-27 | 2001-09-11 | アリアド ジーン セラピューティクス インコーポレイテッド | キメラ転写アクチベーター、ならびにそれに関連する組成物および使用 |
| JP2002508971A (ja) | 1998-01-15 | 2002-03-26 | アリアド・ジーン・セラピューティクス・インコーポレーテッド | 多量体キメラ蛋白質を使用する生物学的イベントの調節 |
| JP2002503667A (ja) | 1998-02-13 | 2002-02-05 | プレジデント・アンド・フェローズ・オブ・ハーバード・カレッジ | 新規な二量体化剤、その製造および使用 |
| CA2379166C (en) | 1999-08-09 | 2013-03-26 | Targeted Genetics Corporation | Enhancement of expression of a single-stranded, heterologous nucleotide sequence from recombinant viral vectors by designing the sequence such that it forms instrastrand base pairs |
| US7067526B1 (en) | 1999-08-24 | 2006-06-27 | Ariad Gene Therapeutics, Inc. | 28-epirapalogs |
| MX359371B (es) | 2001-11-13 | 2018-09-25 | Univ Pennsylvania | Un metodo para detectar y/o identificar secuencias del virus adeno-asociado y aislamiento de secuencias novedosas identificadas de ese modo. |
| PT1453547T (pt) | 2001-12-17 | 2016-12-28 | Univ Pennsylvania | Sequências do vírus adeno-associado (aav) do serotipo 8, vetores contendo as mesmas, e utilizações destas |
| EP2345731B1 (en) | 2003-09-30 | 2015-10-21 | The Trustees of the University of Pennsylvania | Adeno-associated virus (AAV) clades, sequences, vectors containing same, and uses thereof |
| ES2525067T3 (es) | 2005-04-07 | 2014-12-17 | The Trustees Of The University Of Pennsylvania | Método de incremento de la función de un vector de AAV |
| JP4495210B2 (ja) | 2005-06-09 | 2010-06-30 | パナソニック株式会社 | 振幅誤差補償装置及び直交度誤差補償装置 |
| US8734809B2 (en) | 2009-05-28 | 2014-05-27 | University Of Massachusetts | AAV's and uses thereof |
| US8927514B2 (en) | 2010-04-30 | 2015-01-06 | City Of Hope | Recombinant adeno-associated vectors for targeted treatment |
| US8628966B2 (en) | 2010-04-30 | 2014-01-14 | City Of Hope | CD34-derived recombinant adeno-associated vectors for stem cell transduction and systemic therapeutic gene transfer |
| WO2012057363A1 (ja) | 2010-10-27 | 2012-05-03 | 学校法人自治医科大学 | 神経系細胞への遺伝子導入のためのアデノ随伴ウイルスビリオン |
| WO2012109570A1 (en) | 2011-02-10 | 2012-08-16 | The University Of North Carolina At Chapel Hill | Viral vectors with modified transduction profiles and methods of making and using the same |
| CN105755044A (zh) | 2011-04-22 | 2016-07-13 | 加利福尼亚大学董事会 | 具有变异衣壳的腺相关病毒病毒体及其使用方法 |
| ES2857773T5 (es) | 2011-08-24 | 2024-06-04 | Univ Leland Stanford Junior | Nuevas proteínas de la cápside de AAV para la transferencia de ácidos nucleicos |
| WO2013170078A1 (en) | 2012-05-09 | 2013-11-14 | Oregon Health & Science University | Adeno associated virus plasmids and vectors |
| US9393370B2 (en) | 2012-05-24 | 2016-07-19 | Altaviz Llc | Viscous fluid injector |
| CA2905952A1 (en) | 2013-03-13 | 2014-10-02 | The Children's Hospital Of Philadelphia | Adeno-associated virus vectors and methods of use thereof |
| ES2739288T3 (es) | 2013-09-13 | 2020-01-30 | California Inst Of Techn | Recuperación selectiva |
| CN106232618A (zh) | 2013-10-11 | 2016-12-14 | 马萨诸塞眼科耳科诊所 | 预测祖先病毒序列的方法及其用途 |
| WO2015164757A1 (en) | 2014-04-25 | 2015-10-29 | Oregon Health & Science University | Methods of viral neutralizing antibody epitope mapping |
| US10064752B2 (en) | 2014-09-11 | 2018-09-04 | Orbit Biomedical Limited | Motorized suprachoroidal injection of therapeutic agent |
| US11071643B2 (en) | 2014-11-28 | 2021-07-27 | Visionisti Oy | Ocular therapeutics tool |
| USD878575S1 (en) | 2015-11-24 | 2020-03-17 | Visionisti Oy | Hand operated medical instrument |
| SG11201808426XA (en) | 2016-04-15 | 2018-10-30 | Univ Pennsylvania | Compositions for treatment of wet age-related macular degeneration |
| KR20240005973A (ko) * | 2016-04-15 | 2024-01-12 | 리젠엑스바이오 인크. | 완전히-인간형의 번역후 변형된 항-VEGF Fab를 이용한 눈 질환의 치료 |
| EP3687464A4 (en) | 2017-09-27 | 2021-09-29 | REGENXBIO Inc. | TREATMENT OF EYE DISEASES WITH A TOTALLY HUMAN POST-TRANSLATION MODIFIED ANTI-VEGF FAB |
| AU2018350990A1 (en) * | 2017-10-18 | 2020-05-21 | Regenxbio Inc. | Treatment of ocular diseases and metastatic colon cancer with human post-translationally modified VEGF-Trap |
| US11071824B2 (en) | 2017-11-04 | 2021-07-27 | Altaviz, Llc | Injection devices and methods for making and using them |
| US10912883B2 (en) | 2017-11-04 | 2021-02-09 | Altaviz, Llc | Gas-powered fluid injection system |
-
2020
- 2020-08-25 CN CN202080070135.9A patent/CN114502197A/zh active Pending
- 2020-08-25 EP EP20771671.3A patent/EP4021936A1/en active Pending
- 2020-08-25 CA CA3149401A patent/CA3149401A1/en active Pending
- 2020-08-25 MX MX2022002366A patent/MX2022002366A/es unknown
- 2020-08-25 JP JP2022513859A patent/JP2022545967A/ja active Pending
- 2020-08-25 KR KR1020227009810A patent/KR20220051246A/ko not_active Ceased
- 2020-08-25 US US17/638,517 patent/US20220280608A1/en active Pending
- 2020-08-25 BR BR112022003811A patent/BR112022003811A2/pt unknown
- 2020-08-25 AU AU2020336314A patent/AU2020336314A1/en active Pending
- 2020-08-25 WO PCT/US2020/047733 patent/WO2021041373A1/en not_active Ceased
-
2022
- 2022-02-24 IL IL290863A patent/IL290863A/en unknown
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