JP2022545439A - 新規il-21プロドラッグおよびその使用方法 - Google Patents

新規il-21プロドラッグおよびその使用方法 Download PDF

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JP2022545439A
JP2022545439A JP2022510921A JP2022510921A JP2022545439A JP 2022545439 A JP2022545439 A JP 2022545439A JP 2022510921 A JP2022510921 A JP 2022510921A JP 2022510921 A JP2022510921 A JP 2022510921A JP 2022545439 A JP2022545439 A JP 2022545439A
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seq
prodrug
amino acid
acid sequence
antibody
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JP2022545439A5 (https=
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ルゥ.ユエフォン
ユィ,チュンシャオ
リウ,リーチン
ルゥ,ジエン-フォン(ジェフ)
チャン(レイ) チャン,ジュイ
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Askgene Pharma Inc
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Askgene Pharma Inc
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    • A61K47/6889Conjugates wherein the antibody being the modifying agent and wherein the linker, binder or spacer confers particular properties to the conjugates, e.g. peptidic enzyme-labile linkers or acid-labile linkers, providing for an acid-labile immuno conjugate wherein the drug may be released from its antibody conjugated part in an acidic, e.g. tumoural or environment
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