CN115605504A - 新型il-21前药及其使用方法 - Google Patents
新型il-21前药及其使用方法 Download PDFInfo
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- CN115605504A CN115605504A CN202080077926.4A CN202080077926A CN115605504A CN 115605504 A CN115605504 A CN 115605504A CN 202080077926 A CN202080077926 A CN 202080077926A CN 115605504 A CN115605504 A CN 115605504A
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Applications Claiming Priority (9)
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| US202063027138P | 2020-05-19 | 2020-05-19 | |
| US63/027,138 | 2020-05-19 | ||
| US202063047251P | 2020-07-01 | 2020-07-01 | |
| US63/047,251 | 2020-07-01 | ||
| US202063053663P | 2020-07-19 | 2020-07-19 | |
| US63/053,663 | 2020-07-19 | ||
| PCT/US2020/047522 WO2021035188A1 (en) | 2019-08-21 | 2020-08-21 | Novel il-21 prodrugs and methods of use thereof |
Publications (1)
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| CN115605504A true CN115605504A (zh) | 2023-01-13 |
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| EP (1) | EP4017594A1 (https=) |
| JP (1) | JP2022545439A (https=) |
| CN (1) | CN115605504A (https=) |
| WO (1) | WO2021035188A1 (https=) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2024083226A1 (zh) * | 2022-10-21 | 2024-04-25 | 北京诺诚健华医药科技有限公司 | 抗体融合蛋白及其制备和应用 |
| CN118546233A (zh) * | 2024-07-30 | 2024-08-27 | 成都微芯新域生物技术有限公司 | 白介素-21突变体及其应用 |
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|---|---|---|---|---|
| WO2020023702A1 (en) | 2018-07-25 | 2020-01-30 | AskGene Pharma, Inc. | Novel il-21 prodrugs and methods of use thereof |
| US20220002370A1 (en) | 2018-09-27 | 2022-01-06 | Xilio Development, Inc. | Masked cytokine polypeptides |
| CA3141626A1 (en) | 2019-06-12 | 2020-12-17 | AskGene Pharma, Inc. | Novel il-15 prodrugs and methods of use thereof |
| CA3165927A1 (en) | 2020-01-11 | 2021-07-15 | AskGene Pharma, Inc. | Novel masked cytokines and methods of use thereof |
| WO2021207669A1 (en) | 2020-04-10 | 2021-10-14 | Cytomx Therapeutics, Inc. | Activatable cytokine constructs and related compositions and methods |
| IL298136A (en) | 2020-05-13 | 2023-01-01 | Bonum Therapeutics Inc | Preparations of protein complexes and methods of using them |
| WO2022115865A2 (en) | 2020-11-25 | 2022-06-02 | Xilio Development, Inc. | Tumor-specific cleavable linkers |
| BR112023018735A2 (pt) | 2021-03-16 | 2023-11-28 | Cytomx Therapeutics Inc | Construtos de citocinas ativáveis mascarados e composições e métodos relacionados |
| CN118043079A (zh) * | 2021-06-17 | 2024-05-14 | 格治(香港)生物科技有限公司 | 免疫缀合物分子及其相关方法和组合物 |
| JP2024537846A (ja) * | 2021-09-30 | 2024-10-16 | ユノヴィア, カンパニー リミテッド | Il-21r変異タンパク質を含有する免疫サイトカイン |
| JP2025508882A (ja) * | 2022-02-28 | 2025-04-10 | エクシリオ デベロップメント, インコーポレイテッド | 標的化サイトカインおよびその使用方法 |
| EP4504764A1 (en) * | 2022-05-26 | 2025-02-12 | Caribou Biosciences, Inc. | Cytokine-receptor fusions for immune cell stimulation |
| WO2024015960A1 (en) * | 2022-07-15 | 2024-01-18 | Xilio Development, Inc. | Engineered cleavable fc domain as carriers and methods of use thereof |
| WO2025191139A1 (en) * | 2024-03-15 | 2025-09-18 | Avidicure Ip B.V. | Conjugates of her2-specific antigen binding proteins and cytokines |
| EP4671273A1 (en) * | 2024-06-26 | 2025-12-31 | Anaveon AG | INTERLEUKIN 21 PROXIMITY ACTIVATED |
| WO2026003219A1 (en) * | 2024-06-26 | 2026-01-02 | Anaveon AG | Proximity activated interleukin 21 |
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| CN108350055A (zh) * | 2015-10-01 | 2018-07-31 | 热生物制品有限公司 | 作为异源嵌合蛋白邻接i型和ii型胞外结构域的组合物和方法 |
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- 2020-08-21 EP EP20768740.1A patent/EP4017594A1/en not_active Withdrawn
- 2020-08-21 CN CN202080077926.4A patent/CN115605504A/zh active Pending
- 2020-08-21 JP JP2022510921A patent/JP2022545439A/ja active Pending
- 2020-08-21 WO PCT/US2020/047522 patent/WO2021035188A1/en not_active Ceased
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| WO2024083226A1 (zh) * | 2022-10-21 | 2024-04-25 | 北京诺诚健华医药科技有限公司 | 抗体融合蛋白及其制备和应用 |
| CN118546233A (zh) * | 2024-07-30 | 2024-08-27 | 成都微芯新域生物技术有限公司 | 白介素-21突变体及其应用 |
Also Published As
| Publication number | Publication date |
|---|---|
| WO2021035188A1 (en) | 2021-02-25 |
| US20220289822A1 (en) | 2022-09-15 |
| EP4017594A1 (en) | 2022-06-29 |
| JP2022545439A (ja) | 2022-10-27 |
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