JP2022544308A5 - - Google Patents

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Publication number
JP2022544308A5
JP2022544308A5 JP2022509040A JP2022509040A JP2022544308A5 JP 2022544308 A5 JP2022544308 A5 JP 2022544308A5 JP 2022509040 A JP2022509040 A JP 2022509040A JP 2022509040 A JP2022509040 A JP 2022509040A JP 2022544308 A5 JP2022544308 A5 JP 2022544308A5
Authority
JP
Japan
Prior art keywords
lrp5
seq
antibody
cdr
sequence
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2022509040A
Other languages
English (en)
Japanese (ja)
Other versions
JP7840842B2 (ja
JP2022544308A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/CA2020/051119 external-priority patent/WO2021026665A1/en
Publication of JP2022544308A publication Critical patent/JP2022544308A/ja
Publication of JP2022544308A5 publication Critical patent/JP2022544308A5/ja
Application granted granted Critical
Publication of JP7840842B2 publication Critical patent/JP7840842B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

JP2022509040A 2019-08-14 2020-08-14 Lrp5タンパク質に結合する抗体および使用方法 Active JP7840842B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201962886913P 2019-08-14 2019-08-14
US62/886,913 2019-08-14
PCT/CA2020/051119 WO2021026665A1 (en) 2019-08-14 2020-08-14 Antibodies that bind to lrp5 proteins and methods of use

Publications (3)

Publication Number Publication Date
JP2022544308A JP2022544308A (ja) 2022-10-17
JP2022544308A5 true JP2022544308A5 (https=) 2023-08-21
JP7840842B2 JP7840842B2 (ja) 2026-04-06

Family

ID=74570326

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2022509040A Active JP7840842B2 (ja) 2019-08-14 2020-08-14 Lrp5タンパク質に結合する抗体および使用方法

Country Status (10)

Country Link
US (1) US20230183336A1 (https=)
EP (1) EP4013791A4 (https=)
JP (1) JP7840842B2 (https=)
KR (1) KR20220078568A (https=)
CN (2) CN119798435A (https=)
AU (1) AU2020329092A1 (https=)
CA (1) CA3147827A1 (https=)
IL (1) IL290509A (https=)
MX (1) MX2022001947A (https=)
WO (1) WO2021026665A1 (https=)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2023250402A2 (en) * 2022-06-22 2023-12-28 Antlera Therapeutics Inc. Tetravalent fzd and wnt co-receptor binding antibody molecules and uses thereof
WO2022212429A1 (en) * 2021-03-31 2022-10-06 Sachdev Sidhu Anti-viral compositions for rift valley fever virus infections and methods of using same
EP4547713A2 (en) * 2022-06-30 2025-05-07 The University of Chicago Cd73 (nt5e) targeting polypeptides

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2004261980A1 (en) * 2003-08-01 2005-02-10 Genentech, Inc. Antibody CDR polypeptide sequences with restricted diversity
US20070149496A1 (en) * 2003-10-31 2007-06-28 Jack Tuszynski Water-soluble compound
US8790650B2 (en) * 2011-04-28 2014-07-29 Vanderbilt University Methods of using an antibody to inhibit WNT-mediated cardiac remodeling
US9200072B2 (en) * 2012-01-18 2015-12-01 Genentech Inc. Anti-LRP5 antibodies and methods of use
US20190194314A1 (en) * 2012-12-21 2019-06-27 Stowers Institute For Medical Research Antibodies for modulating binding between lrp and wise
US10294294B2 (en) * 2015-09-10 2019-05-21 Albert Einstein College Of Medicine Synthetic antibodies to BAX and uses thereof
UA122079C2 (uk) * 2015-12-04 2020-09-10 Бьорінгер Інгельхайм Інтернаціональ Гмбх Поліпептид, що специфічно зв'язується з lrp5 і lrp6
CA3077518C (en) * 2016-09-07 2021-10-19 Frederic Fellouse Synthetic antibodies against vegf and their uses
EP3630816B1 (en) * 2017-05-31 2024-03-20 Boehringer Ingelheim International GmbH Polypeptides antagonizing wnt signaling in tumor cells
EP3700930A1 (en) * 2017-10-25 2020-09-02 The Regents of the University of California Antibodies against cdcp1 for the treatment and detection of cancer
CA3080120C (en) * 2017-10-27 2023-11-21 New York University Anti-galectin-9 antibodies and uses thereof
CN111699003B (zh) 2017-12-19 2024-05-03 瑟罗泽恩奥普瑞汀公司 抗lrp5/6抗体和使用方法
JP7550647B2 (ja) * 2018-02-14 2024-09-20 アントレラ セラピューティクス インコーポレイテッド Wntシグナル伝達を活性化する多価結合分子およびその使用
US10640562B2 (en) * 2018-07-17 2020-05-05 Mcmaster University T cell-antigen coupler with various construct optimizations
CA3111087A1 (en) * 2018-08-29 2020-03-05 Nanjing Legend Biotech Co., Ltd. Anti-mesothelin chimeric antigen receptor (car) constructs and uses thereof

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