JP2022543191A5 - - Google Patents
Info
- Publication number
- JP2022543191A5 JP2022543191A5 JP2022502227A JP2022502227A JP2022543191A5 JP 2022543191 A5 JP2022543191 A5 JP 2022543191A5 JP 2022502227 A JP2022502227 A JP 2022502227A JP 2022502227 A JP2022502227 A JP 2022502227A JP 2022543191 A5 JP2022543191 A5 JP 2022543191A5
- Authority
- JP
- Japan
- Prior art keywords
- oligonucleotide
- oligonucleotide according
- present
- multimerized
- covalent
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201962880591P | 2019-07-30 | 2019-07-30 | |
| US62/880,591 | 2019-07-30 | ||
| PCT/US2020/044110 WO2021021959A2 (en) | 2019-07-30 | 2020-07-29 | Subcutaneous delivery of multimeric oligonucleotides with enhanced bioactivity |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2022543191A JP2022543191A (ja) | 2022-10-11 |
| JP2022543191A5 true JP2022543191A5 (enExample) | 2023-08-07 |
Family
ID=74228530
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022502227A Withdrawn JP2022543191A (ja) | 2019-07-30 | 2020-07-29 | 増強された生理活性を有する多量体オリゴヌクレオチドの皮下送達 |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US20230114023A1 (enExample) |
| EP (1) | EP4004205A4 (enExample) |
| JP (1) | JP2022543191A (enExample) |
| CN (1) | CN114466929A (enExample) |
| AU (1) | AU2020319911A1 (enExample) |
| CA (1) | CA3144467A1 (enExample) |
| IL (1) | IL289801A (enExample) |
| WO (1) | WO2021021959A2 (enExample) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR101141544B1 (ko) | 2009-03-13 | 2012-05-03 | 한국과학기술원 | 에스아이알엔에이 다중 접합체 및 이의 제조방법 |
| IL316159A (en) | 2015-06-15 | 2024-12-01 | Mpeg La Llc | Defined Oligonucleotide Multimers and Methods for Manufacture Thereof |
| SG11201906728TA (en) | 2017-02-06 | 2019-08-27 | Mpeg La Llc | Multimeric oligonucleotides having decreased kidney clearance |
| US20230372508A1 (en) * | 2022-05-19 | 2023-11-23 | Olix Us, Inc. | Linkers coupling functional ligands to macromolecules |
| WO2025100427A1 (ja) * | 2023-11-06 | 2025-05-15 | 国立研究開発法人国立循環器病研究センター | 肺高血圧症の予防および／または治療用医薬 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20060035815A1 (en) * | 2004-05-04 | 2006-02-16 | Nastech Pharmaceutical Company Inc. | Pharmaceutical compositions for delivery of ribonucleic acid to a cell |
| SI2539451T1 (sl) * | 2010-02-24 | 2016-04-29 | Arrowhead Research Corporation | Sestavki za ciljano dostavo sirna |
| US20150247141A1 (en) * | 2012-09-14 | 2015-09-03 | Rana Therapeutics, Inc. | Multimeric oligonucleotide compounds |
| CN104837996A (zh) * | 2012-11-15 | 2015-08-12 | 罗氏创新中心哥本哈根有限公司 | 抗apob反义缀合物化合物 |
| AU2014211406B2 (en) * | 2013-01-30 | 2019-07-18 | Roche Innovation Center Copenhagen A/S | LNA oligonucleotide carbohydrate conjugates |
| IL316159A (en) * | 2015-06-15 | 2024-12-01 | Mpeg La Llc | Defined Oligonucleotide Multimers and Methods for Manufacture Thereof |
| SG11201906728TA (en) * | 2017-02-06 | 2019-08-27 | Mpeg La Llc | Multimeric oligonucleotides having decreased kidney clearance |
-
2020
- 2020-07-29 JP JP2022502227A patent/JP2022543191A/ja not_active Withdrawn
- 2020-07-29 AU AU2020319911A patent/AU2020319911A1/en not_active Abandoned
- 2020-07-29 US US17/631,087 patent/US20230114023A1/en not_active Abandoned
- 2020-07-29 WO PCT/US2020/044110 patent/WO2021021959A2/en not_active Ceased
- 2020-07-29 CA CA3144467A patent/CA3144467A1/en active Pending
- 2020-07-29 EP EP20848521.9A patent/EP4004205A4/en not_active Withdrawn
- 2020-07-29 CN CN202080068000.9A patent/CN114466929A/zh active Pending
-
2022
- 2022-01-12 IL IL289801A patent/IL289801A/en unknown
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