JP2022543112A5 - - Google Patents
Info
- Publication number
- JP2022543112A5 JP2022543112A5 JP2022506729A JP2022506729A JP2022543112A5 JP 2022543112 A5 JP2022543112 A5 JP 2022543112A5 JP 2022506729 A JP2022506729 A JP 2022506729A JP 2022506729 A JP2022506729 A JP 2022506729A JP 2022543112 A5 JP2022543112 A5 JP 2022543112A5
- Authority
- JP
- Japan
- Prior art keywords
- cells
- gene
- sequence encoding
- group
- dux4
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201962881840P | 2019-08-01 | 2019-08-01 | |
| US62/881,840 | 2019-08-01 | ||
| PCT/US2020/044635 WO2021022223A1 (en) | 2019-08-01 | 2020-07-31 | Dux4 expressing cells and uses thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2022543112A JP2022543112A (ja) | 2022-10-07 |
| JP2022543112A5 true JP2022543112A5 (enExample) | 2023-08-08 |
Family
ID=72088403
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022506729A Pending JP2022543112A (ja) | 2019-08-01 | 2020-07-31 | Dux4発現細胞およびそれらの使用 |
Country Status (4)
| Country | Link |
|---|---|
| US (1) | US20220267732A1 (enExample) |
| EP (1) | EP4007596A1 (enExample) |
| JP (1) | JP2022543112A (enExample) |
| WO (1) | WO2021022223A1 (enExample) |
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US11162079B2 (en) | 2019-05-10 | 2021-11-02 | The Regents Of The University Of California | Blood type O Rh-hypo-immunogenic pluripotent cells |
| US11459372B2 (en) | 2020-11-30 | 2022-10-04 | Crispr Therapeutics Ag | Gene-edited natural killer cells |
| US11473060B2 (en) | 2020-12-30 | 2022-10-18 | Crispr Therapeutics Ag | Compositions and methods for differentiating stem cells into NK cells |
| CA3200509A1 (en) | 2020-12-31 | 2022-07-07 | Sonja SCHREPFER | Methods and compositions for modulating car-t activity |
| WO2022251443A1 (en) * | 2021-05-26 | 2022-12-01 | FUJIFILM Cellular Dynamics, Inc. | Methods to prevent rapid silencing of genes in pluripotent stem cells |
| WO2022269393A1 (en) * | 2021-06-23 | 2022-12-29 | Crispr Therapeutics Ag | Engineered cells with improved protection from natural killer cell killing |
| EP4370544A2 (en) | 2021-07-14 | 2024-05-22 | Sana Biotechnology, Inc. | Altered expression of y chromosome-linked antigens in hypoimmunogenic cells |
| JP2024534771A (ja) * | 2021-08-11 | 2024-09-26 | サナ バイオテクノロジー,インコーポレイテッド | 補体媒介性炎症反応を低減するための同種異系細胞療法のための遺伝子改変細胞 |
| MX2024001443A (es) | 2021-08-11 | 2024-05-15 | Sana Biotechnology Inc | Sistemas inducibles para alterar la expresión génica en células hipoinmunógenas. |
| WO2023086988A1 (en) * | 2021-11-12 | 2023-05-19 | Fred Hutchinson Cancer Center | Dux4 polypeptides and nucleic acids for treating inflammatory and autoimmune conditions |
| MX2024007528A (es) | 2021-12-23 | 2024-08-30 | Sana Biotechnology Inc | Linfocitos t del receptor de antígeno quimérico (car) para el tratamiento de enfermedades autoinmunitarias y métodos asociados. |
| US20250302953A1 (en) | 2022-02-14 | 2025-10-02 | Sana Biotechnology, Inc. | Methods of treating patients exhibiting a prior failed therapy with hypoimmunogenic cells |
| US20240010991A1 (en) * | 2022-07-01 | 2024-01-11 | Janssen Biotech, Inc. | Materials and methods for bioengineered ipsc populations |
| WO2024012420A1 (zh) * | 2022-07-11 | 2024-01-18 | 士泽生物医药(苏州)有限公司 | 一种表达faslg的通用型细胞及其制备方法 |
| JP2026501446A (ja) * | 2022-12-16 | 2026-01-15 | ゼルスマート バイオ‐ファーマシューティカル (スズホウ) シーオー., エルティーディー. | ユニバーサル細胞及びその製造方法 |
| WO2025117331A1 (en) | 2023-12-01 | 2025-06-05 | Eli Lilly And Company | Methods of making stem cell-derived islet-like cells, as well as populations and compositions including the same |
| WO2025230941A1 (en) | 2024-04-30 | 2025-11-06 | Satellite Biosciences, Inc. | Hypoimmunogenic cell mixtures and methods of use thereof |
| WO2025230947A1 (en) | 2024-04-30 | 2025-11-06 | Satellite Biosciences, Inc. | Engineered hepatocytes for secreting polypeptides |
| GB202415025D0 (en) * | 2024-10-11 | 2024-11-27 | Ospedale San Raffaele Srl | Cell |
Family Cites Families (36)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5422251A (en) | 1986-11-26 | 1995-06-06 | Princeton University | Triple-stranded nucleic acids |
| GB8724885D0 (en) | 1987-10-23 | 1987-11-25 | Binns M M | Fowlpox virus promotors |
| US5176996A (en) | 1988-12-20 | 1993-01-05 | Baylor College Of Medicine | Method for making synthetic oligonucleotides which bind specifically to target sites on duplex DNA molecules, by forming a colinear triplex, the synthetic oligonucleotides and methods of use |
| US5420032A (en) | 1991-12-23 | 1995-05-30 | Universitge Laval | Homing endonuclease which originates from chlamydomonas eugametos and recognizes and cleaves a 15, 17 or 19 degenerate double stranded nucleotide sequence |
| US5792632A (en) | 1992-05-05 | 1998-08-11 | Institut Pasteur | Nucleotide sequence encoding the enzyme I-SceI and the uses thereof |
| DE19539493A1 (de) | 1995-10-24 | 1997-04-30 | Thomae Gmbh Dr K | Starker homologer Promotor aus Hamster |
| GB9710809D0 (en) | 1997-05-23 | 1997-07-23 | Medical Res Council | Nucleic acid binding proteins |
| GB9710807D0 (en) | 1997-05-23 | 1997-07-23 | Medical Res Council | Nucleic acid binding proteins |
| US6140081A (en) | 1998-10-16 | 2000-10-31 | The Scripps Research Institute | Zinc finger binding domains for GNN |
| US7070934B2 (en) | 1999-01-12 | 2006-07-04 | Sangamo Biosciences, Inc. | Ligand-controlled regulation of endogenous gene expression |
| US6453242B1 (en) | 1999-01-12 | 2002-09-17 | Sangamo Biosciences, Inc. | Selection of sites for targeting by zinc finger proteins and methods of designing zinc finger proteins to bind to preselected sites |
| US6534261B1 (en) | 1999-01-12 | 2003-03-18 | Sangamo Biosciences, Inc. | Regulation of endogenous gene expression in cells using zinc finger proteins |
| US6599692B1 (en) | 1999-09-14 | 2003-07-29 | Sangamo Bioscience, Inc. | Functional genomics using zinc finger proteins |
| US7030215B2 (en) | 1999-03-24 | 2006-04-18 | Sangamo Biosciences, Inc. | Position dependent recognition of GNN nucleotide triplets by zinc fingers |
| US6794136B1 (en) | 2000-11-20 | 2004-09-21 | Sangamo Biosciences, Inc. | Iterative optimization in the design of binding proteins |
| HK1049515B (en) | 1999-12-06 | 2006-01-13 | Sangamo Biosciences Inc. | Methods of using randomized libraries of zinc finger proteins for the identification of gene function |
| DE60143192D1 (de) | 2000-02-08 | 2010-11-18 | Sangamo Biosciences Inc | Zellen zur entdeckung von medikamenten |
| JP2002060786A (ja) | 2000-08-23 | 2002-02-26 | Kao Corp | 硬質表面用殺菌防汚剤 |
| US7067317B2 (en) | 2000-12-07 | 2006-06-27 | Sangamo Biosciences, Inc. | Regulation of angiogenesis with zinc finger proteins |
| WO2003016496A2 (en) | 2001-08-20 | 2003-02-27 | The Scripps Research Institute | Zinc finger binding domains for cnn |
| US7262054B2 (en) | 2002-01-22 | 2007-08-28 | Sangamo Biosciences, Inc. | Zinc finger proteins for DNA binding and gene regulation in plants |
| US7361635B2 (en) | 2002-08-29 | 2008-04-22 | Sangamo Biosciences, Inc. | Simultaneous modulation of multiple genes |
| US7888121B2 (en) | 2003-08-08 | 2011-02-15 | Sangamo Biosciences, Inc. | Methods and compositions for targeted cleavage and recombination |
| US7972854B2 (en) | 2004-02-05 | 2011-07-05 | Sangamo Biosciences, Inc. | Methods and compositions for targeted cleavage and recombination |
| EP1737498A2 (en) | 2004-04-08 | 2007-01-03 | Sangamo Biosciences Inc. | Zinc finger proteins for treatment of neuropathic pain |
| JP4903689B2 (ja) | 2004-04-08 | 2012-03-28 | サンガモ バイオサイエンシズ インコーポレイテッド | 神経障害および神経変性症状を治療するための方法と組成物 |
| EP2650366B1 (en) | 2005-10-18 | 2017-03-22 | Precision Biosciences | Rationally designed meganucleases with altered sequence specificity and DNA-binding affinity |
| EP3156062A1 (en) | 2010-05-17 | 2017-04-19 | Sangamo BioSciences, Inc. | Novel dna-binding proteins and uses thereof |
| US9089520B2 (en) | 2010-05-21 | 2015-07-28 | Baylor College Of Medicine | Methods for inducing selective apoptosis |
| JP5996630B2 (ja) | 2011-04-05 | 2016-09-21 | セレクティスCellectis | コンパクトtale−ヌクレアーゼを作製する方法及びその使用 |
| NZ629427A (en) | 2012-02-29 | 2016-04-29 | Sangamo Biosciences Inc | Methods and compositions for treating huntington’s disease |
| CA2988854A1 (en) | 2015-05-08 | 2016-11-17 | President And Fellows Of Harvard College | Universal donor stem cells and related methods |
| WO2018073787A2 (en) * | 2016-10-19 | 2018-04-26 | Fred Hutchinson Cancer Research Center | Compositions and methods for reprogramming cells and for somatic cell nuclear transfer using duxc expression |
| KR20190103373A (ko) | 2017-01-13 | 2019-09-04 | 더 리젠츠 오브 더 유니버시티 오브 캘리포니아 | 면역조작된 만능 세포 |
| CN110637083A (zh) | 2017-03-20 | 2019-12-31 | 华盛顿大学 | 细胞及其使用和制备方法 |
| WO2020028134A1 (en) * | 2018-07-30 | 2020-02-06 | Fred Hutchinson Cancer Research Center | Methods and compositions for treating cancer |
-
2020
- 2020-07-31 WO PCT/US2020/044635 patent/WO2021022223A1/en not_active Ceased
- 2020-07-31 EP EP20757473.2A patent/EP4007596A1/en active Pending
- 2020-07-31 JP JP2022506729A patent/JP2022543112A/ja active Pending
- 2020-07-31 US US17/632,026 patent/US20220267732A1/en active Pending
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