JP2022541520A5 - - Google Patents
Info
- Publication number
- JP2022541520A5 JP2022541520A5 JP2022502928A JP2022502928A JP2022541520A5 JP 2022541520 A5 JP2022541520 A5 JP 2022541520A5 JP 2022502928 A JP2022502928 A JP 2022502928A JP 2022502928 A JP2022502928 A JP 2022502928A JP 2022541520 A5 JP2022541520 A5 JP 2022541520A5
- Authority
- JP
- Japan
- Prior art keywords
- amino acid
- composition according
- acid sequence
- seq
- sequence
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| NL2023505 | 2019-07-15 | ||
| NL2023505 | 2019-07-15 | ||
| PCT/IB2020/056635 WO2021009684A1 (en) | 2019-07-15 | 2020-07-15 | Modified aav capsid proteins for treatment of arthritic disease |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2022541520A JP2022541520A (ja) | 2022-09-26 |
| JP2022541520A5 true JP2022541520A5 (enExample) | 2023-07-21 |
| JP7681277B2 JP7681277B2 (ja) | 2025-05-22 |
Family
ID=68425203
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022502928A Active JP7681277B2 (ja) | 2019-07-15 | 2020-07-15 | 関節炎疾患の治療のための修飾ａａｖキャプシドタンパク質 |
Country Status (23)
| Country | Link |
|---|---|
| US (1) | US20220267797A1 (enExample) |
| EP (1) | EP3999119B1 (enExample) |
| JP (1) | JP7681277B2 (enExample) |
| KR (1) | KR20220081971A (enExample) |
| CN (1) | CN114502737B (enExample) |
| AU (1) | AU2020314883A1 (enExample) |
| BR (1) | BR112022000724A2 (enExample) |
| CA (1) | CA3146791A1 (enExample) |
| DK (1) | DK3999119T3 (enExample) |
| ES (1) | ES2998884T3 (enExample) |
| FI (1) | FI3999119T3 (enExample) |
| HR (1) | HRP20241647T1 (enExample) |
| HU (1) | HUE069369T2 (enExample) |
| IL (1) | IL289826A (enExample) |
| LT (1) | LT3999119T (enExample) |
| MX (1) | MX2022000551A (enExample) |
| PH (1) | PH12022550109A1 (enExample) |
| PL (1) | PL3999119T3 (enExample) |
| PT (1) | PT3999119T (enExample) |
| RS (1) | RS66255B1 (enExample) |
| SI (1) | SI3999119T1 (enExample) |
| SM (1) | SMT202400486T1 (enExample) |
| WO (1) | WO2021009684A1 (enExample) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP7389040B2 (ja) * | 2018-01-17 | 2023-11-29 | メイラジーティーエックス・ユーケー・ザ・セカンド・リミテッド | 遺伝子治療のための修飾ｒＡＡＶキャプシドタンパク質 |
| WO2022198126A1 (en) * | 2021-03-19 | 2022-09-22 | Washington University | Methods for generating mechanically-responsive cells and uses thereof |
| KR20240095539A (ko) | 2021-10-08 | 2024-06-25 | 디노 테라퓨틱스, 인코포레이티드 | 캡시드 변이체 및 이의 사용 방법 |
| WO2023125481A1 (zh) * | 2021-12-28 | 2023-07-06 | 成都弘基生物科技有限公司 | 经过修饰的aav衣壳蛋白及其用途 |
| JP2026509271A (ja) | 2023-03-10 | 2026-03-17 | ダイノ セラピューティクス，インコーポレーテッド | カプシドポリペプチドおよびその使用方法 |
| EP4694906A1 (en) | 2023-04-13 | 2026-02-18 | MeiraGTx Gene Regulation Limited | Inflammation-inducible promoters |
| KR20260082361A (ko) | 2023-08-31 | 2026-06-04 | 디노 테라퓨틱스, 인코포레이티드 | 캡시드 폴리펩타이드 및 이의 사용 방법 |
| TW202545971A (zh) | 2024-02-08 | 2025-12-01 | 美商戴諾治療公司 | 殼體多肽及其使用方法 |
| WO2026064442A2 (en) | 2024-09-18 | 2026-03-26 | Dyno Therapeutics, Inc. | Capsid polypeptides and methods of use thereof |
| WO2026122963A1 (en) | 2024-12-06 | 2026-06-11 | Dyno Therapeutics, Inc. | Capsid polypeptides and methods of use thereof |
Family Cites Families (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6723551B2 (en) | 2001-11-09 | 2004-04-20 | The United States Of America As Represented By The Department Of Health And Human Services | Production of adeno-associated virus in insect cells |
| EP1572893B1 (en) | 2001-11-09 | 2009-01-07 | THE GOVERNMENT OF THE UNITED STATES OF AMERICA as represented by THE SECRETARY of the DEPARTMENT OF HEALTH AND HUMAN SERVICES | Production of adeno-associated virus in insect cells |
| DE23193606T1 (de) * | 2005-04-07 | 2024-02-15 | The Trustees Of The University Of Pennsylvania | Verfahren zur erhöhung der funktion eines aav-vektors |
| PT3272872T (pt) | 2005-10-20 | 2020-06-26 | Uniqure Ip Bv | Vetores aav melhorados produzidos em células de insetos |
| WO2007148971A2 (en) | 2006-06-21 | 2007-12-27 | Amsterdam Molecular Therapeutics B.V. | Vectors with modified initiation codon for the translation of aav-rep78 useful for production of aav in insect cells |
| ES2385679T3 (es) | 2006-08-24 | 2012-07-30 | Virovek, Inc. | Expresión de células de insecto de genes con marcos de lectura abiertos superpuestos, métodos y composiciones de éstos |
| EP2012122A1 (en) * | 2007-07-06 | 2009-01-07 | Medigene AG | Mutated parvovirus structural proteins as vaccines |
| HUE029744T2 (en) | 2007-07-26 | 2017-04-28 | Uniqure Ip Bv | Baculoviral vectors comprising repeated coding sequences with differential codon biases |
| AU2009215987B2 (en) | 2008-02-19 | 2015-01-22 | Uniqure Ip B.V. | Optimisation of expression of parvoviral rep and cap proteins in insect cells |
| US20110171262A1 (en) | 2008-06-17 | 2011-07-14 | Andrew Christian Bakker | Parvoviral capsid with incorporated gly-ala repeat region |
| EP2545165B1 (en) | 2010-03-11 | 2020-07-29 | uniQure IP B.V. | Mutated rep encoding sequences for use in aav production |
| JP6198278B2 (ja) | 2011-09-08 | 2017-09-20 | ユニキュアー アイピー ビー．ブイ． | Ａａｖ調製物からの混入ウイルスの除去 |
| WO2013174760A1 (en) * | 2012-05-25 | 2013-11-28 | Deutsches Krebsforschungszentrum | Optimized aav-vectors for high transduction rates in dendritic cells |
| DE102013215817A1 (de) * | 2013-08-09 | 2015-02-12 | Universitätsklinikum Hamburg-Eppendorf | Neue peptide mit spezifität für die lunge |
| GB201403684D0 (en) * | 2014-03-03 | 2014-04-16 | King S College London | Vector |
| LT3137497T (lt) * | 2014-05-02 | 2021-07-26 | Genzyme Corporation | Aav vektoriai, skirti tinklainės ir cns genų terapijai |
| CN107002096A (zh) | 2014-10-06 | 2017-08-01 | 阿罗根有限公司 | 基于aav的基因疗法 |
| US20180057839A1 (en) * | 2014-11-26 | 2018-03-01 | The Regents Of The University Of California | Therapeutic compositions comprising transcription factors and methods of making and using the same |
| WO2017197355A2 (en) * | 2016-05-13 | 2017-11-16 | 4D Molecular Therapeutics Inc. | Adeno-associated virus variant capsids and methods of use thereof |
| ES2982489T3 (es) * | 2016-08-19 | 2024-10-16 | Univ Florida | Composiciones para el tratamiento de afecciones que utilizan virus adeno-asociados recombinantes autocomplementarios |
| US11958886B2 (en) * | 2016-12-07 | 2024-04-16 | University Of Florida Research Foundation, Incorporated | IL-1RA cDNAs |
| EP4219806A3 (en) * | 2017-04-11 | 2023-09-27 | Ruprecht-Karls-Universität Heidelberg | Adeno-associated virus library |
| JP7389040B2 (ja) * | 2018-01-17 | 2023-11-29 | メイラジーティーエックス・ユーケー・ザ・セカンド・リミテッド | 遺伝子治療のための修飾ｒＡＡＶキャプシドタンパク質 |
-
2020
- 2020-07-15 SM SM20240486T patent/SMT202400486T1/it unknown
- 2020-07-15 SI SI202030519T patent/SI3999119T1/sl unknown
- 2020-07-15 EP EP20740418.7A patent/EP3999119B1/en active Active
- 2020-07-15 DK DK20740418.7T patent/DK3999119T3/da active
- 2020-07-15 KR KR1020227004437A patent/KR20220081971A/ko active Pending
- 2020-07-15 HR HRP20241647TT patent/HRP20241647T1/hr unknown
- 2020-07-15 ES ES20740418T patent/ES2998884T3/es active Active
- 2020-07-15 CA CA3146791A patent/CA3146791A1/en active Pending
- 2020-07-15 AU AU2020314883A patent/AU2020314883A1/en not_active Abandoned
- 2020-07-15 PH PH1/2022/550109A patent/PH12022550109A1/en unknown
- 2020-07-15 BR BR112022000724A patent/BR112022000724A2/pt unknown
- 2020-07-15 HU HUE20740418A patent/HUE069369T2/hu unknown
- 2020-07-15 JP JP2022502928A patent/JP7681277B2/ja active Active
- 2020-07-15 US US17/627,364 patent/US20220267797A1/en active Pending
- 2020-07-15 WO PCT/IB2020/056635 patent/WO2021009684A1/en not_active Ceased
- 2020-07-15 MX MX2022000551A patent/MX2022000551A/es unknown
- 2020-07-15 PL PL20740418.7T patent/PL3999119T3/pl unknown
- 2020-07-15 RS RS20241346A patent/RS66255B1/sr unknown
- 2020-07-15 PT PT207404187T patent/PT3999119T/pt unknown
- 2020-07-15 LT LTEPPCT/IB2020/056635T patent/LT3999119T/lt unknown
- 2020-07-15 CN CN202080064732.0A patent/CN114502737B/zh active Active
- 2020-07-15 FI FIEP20740418.7T patent/FI3999119T3/fi active
-
2022
- 2022-01-13 IL IL289826A patent/IL289826A/en unknown
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