JP2022541181A5 - - Google Patents

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Publication number
JP2022541181A5
JP2022541181A5 JP2022502277A JP2022502277A JP2022541181A5 JP 2022541181 A5 JP2022541181 A5 JP 2022541181A5 JP 2022502277 A JP2022502277 A JP 2022502277A JP 2022502277 A JP2022502277 A JP 2022502277A JP 2022541181 A5 JP2022541181 A5 JP 2022541181A5
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JP
Japan
Prior art keywords
cells
antigen
tcr
cell
library
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2022502277A
Other languages
English (en)
Japanese (ja)
Other versions
JP2022541181A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2020/041824 external-priority patent/WO2021011482A1/en
Publication of JP2022541181A publication Critical patent/JP2022541181A/ja
Publication of JP2022541181A5 publication Critical patent/JP2022541181A5/ja
Pending legal-status Critical Current

Links

JP2022502277A 2019-07-15 2020-07-13 Ｔｃｒ遺伝子の単離方法 Pending JP2022541181A (ja)

Applications Claiming Priority (11)

Application Number Priority Date Filing Date Title
US201962874125P 2019-07-15 2019-07-15
US62/874,125 2019-07-15
US202062975924P 2020-02-13 2020-02-13
US62/975,924 2020-02-13
US202063024341P 2020-05-13 2020-05-13
US63/024,341 2020-05-13
US202063034157P 2020-06-03 2020-06-03
US63/034,157 2020-06-03
US202063039346P 2020-06-15 2020-06-15
US63/039,346 2020-06-15
PCT/US2020/041824 WO2021011482A1 (en) 2019-07-15 2020-07-13 Method to isolate tcr genes

Publications (2)

Publication Number Publication Date
JP2022541181A JP2022541181A (ja) 2022-09-22
JP2022541181A5 true JP2022541181A5 (https=) 2023-07-18

Family

ID=74211262

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2022502277A Pending JP2022541181A (ja) 2019-07-15 2020-07-13 Ｔｃｒ遺伝子の単離方法

Country Status (12)

Country Link
US (1) US20210040558A1 (https=)
EP (1) EP3999528A4 (https=)
JP (1) JP2022541181A (https=)
KR (1) KR20220075210A (https=)
CN (1) CN114502579A (https=)
AU (1) AU2020315325A1 (https=)
BR (1) BR112022000790A2 (https=)
CA (1) CA3146845A1 (https=)
CL (1) CL2022000085A1 (https=)
MX (1) MX2022000667A (https=)
TW (1) TW202117014A (https=)
WO (1) WO2021011482A1 (https=)

Families Citing this family (16)

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Publication number Priority date Publication date Assignee Title
LT3428194T (lt) 2017-07-14 2021-12-10 Immatics Biotechnologies Gmbh Pagerinta dvejopo savitumo polipeptido molekulė
GB201819540D0 (en) * 2018-11-30 2019-01-16 Adaptimmune Ltd T cell modification
CN113621070A (zh) 2020-05-06 2021-11-09 华夏英泰（北京）生物技术有限公司 一种t细胞抗原受体、其多聚体复合物及其制备方法和应用
AU2021320556A1 (en) 2020-08-07 2023-03-09 Neogene Therapeutics B.V. Methods to enrich genetically engineered T cells
TW202242097A (zh) 2021-01-20 2022-11-01 荷蘭商新基因治療公司 經工程化之抗原呈現細胞
WO2022233956A1 (en) 2021-05-05 2022-11-10 Immatics Biotechnologies Gmbh Antigen binding proteins specifically binding prame
WO2023010436A1 (zh) * 2021-08-05 2023-02-09 卡瑞济(北京)生命科技有限公司 Tcr表达构建体以及其制备方法和用途
WO2023114994A1 (en) * 2021-12-16 2023-06-22 Board Of Regents, The University Of Texas System Personalized ranking and identification of onco-reactive t cell receptors and uses thereof
CN114134221B (zh) * 2022-01-28 2022-04-08 北京肿瘤医院(北京大学肿瘤医院) 一种筛选肿瘤特异tcr的方法
US20250216381A1 (en) * 2022-03-21 2025-07-03 Alaunos Therapeutics, Inc. Methods for Identifying Neoantigen-Reactive T Cell Receptors
CN115341020A (zh) * 2022-08-29 2022-11-15 深圳市美星生物科技有限公司 一种利用lamp技术的急性心梗和心衰外显子测序方法
EP4638712A2 (en) * 2022-12-22 2025-10-29 Bluesphere Bio, Inc. Methods for identifying t cell receptors (tcrs) that bind antigens
WO2024163607A2 (en) * 2023-02-02 2024-08-08 Board Of Regents, The University Of Texas System T-cell receptors targeting egfr and methods of use thereof
EP4550335A1 (en) * 2023-10-31 2025-05-07 Tempus AI, Inc. T cell receptor screening methods
WO2025213105A1 (en) * 2024-04-04 2025-10-09 Biontech Us Inc. Methods for identifying t-cell receptor (tcr) sequences
WO2025240737A1 (en) * 2024-05-16 2025-11-20 Rutgers, The State University Of New Jersey Methods of producing memory t cells in vitro and their use in immunotherapy

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR102480188B1 (ko) * 2012-09-14 2022-12-21 더 유나이티드 스테이츠 오브 어메리카, 애즈 리프리젠티드 바이 더 세크러테리, 디파트먼트 오브 헬쓰 앤드 휴먼 서비씨즈 Mhc ii형 제한된 mage-a3을 인식하는 t 세포 수용체
EP3234130B1 (en) * 2014-12-19 2020-11-25 The Broad Institute, Inc. Methods for profiling the t-cell- receptor repertoire
JP2019516768A (ja) * 2016-05-25 2019-06-20 ザ カウンシル オブ ザ クイーンズランド インスティテュート オブ メディカル リサーチ がんの治療のための免疫チェックポイント阻害剤及び細胞傷害性ｔ細胞
WO2019196088A1 (en) * 2018-04-13 2019-10-17 Syz Cell Therapy Co. Methods of obtaining tumor-specific t cell receptors

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