JP2022540792A5 - - Google Patents
Info
- Publication number
- JP2022540792A5 JP2022540792A5 JP2021577412A JP2021577412A JP2022540792A5 JP 2022540792 A5 JP2022540792 A5 JP 2022540792A5 JP 2021577412 A JP2021577412 A JP 2021577412A JP 2021577412 A JP2021577412 A JP 2021577412A JP 2022540792 A5 JP2022540792 A5 JP 2022540792A5
- Authority
- JP
- Japan
- Prior art keywords
- sequence
- process according
- target
- specific
- site
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2024188978A JP7898488B2 (ja) | 2019-07-03 | 2024-10-28 | Crisprで導入された二本鎖dna切断修復の同定、特徴付けおよび定量化 |
Applications Claiming Priority (9)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201962870471P | 2019-07-03 | 2019-07-03 | |
| US201962870426P | 2019-07-03 | 2019-07-03 | |
| US62/870,471 | 2019-07-03 | ||
| US62/870,426 | 2019-07-03 | ||
| US201962952598P | 2019-12-23 | 2019-12-23 | |
| US201962952603P | 2019-12-23 | 2019-12-23 | |
| US62/952,603 | 2019-12-23 | ||
| US62/952,598 | 2019-12-23 | ||
| PCT/US2020/040621 WO2021003343A1 (en) | 2019-07-03 | 2020-07-02 | Identification, characterization, and quantitation of crispr-introduced double-stranded dna break repairs |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024188978A Division JP7898488B2 (ja) | 2019-07-03 | 2024-10-28 | Crisprで導入された二本鎖dna切断修復の同定、特徴付けおよび定量化 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2022540792A JP2022540792A (ja) | 2022-09-20 |
| JP2022540792A5 true JP2022540792A5 (cg-RX-API-DMAC10.html) | 2023-04-18 |
| JP7579817B2 JP7579817B2 (ja) | 2024-11-08 |
Family
ID=74065411
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021577412A Active JP7579817B2 (ja) | 2019-07-03 | 2020-07-02 | Crisprで導入された二本鎖dna切断修復の同定、特徴付けおよび定量化 |
| JP2024188978A Active JP7898488B2 (ja) | 2019-07-03 | 2024-10-28 | Crisprで導入された二本鎖dna切断修復の同定、特徴付けおよび定量化 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024188978A Active JP7898488B2 (ja) | 2019-07-03 | 2024-10-28 | Crisprで導入された二本鎖dna切断修復の同定、特徴付けおよび定量化 |
Country Status (7)
| Country | Link |
|---|---|
| US (2) | US12254959B2 (cg-RX-API-DMAC10.html) |
| EP (1) | EP3994258A4 (cg-RX-API-DMAC10.html) |
| JP (2) | JP7579817B2 (cg-RX-API-DMAC10.html) |
| AU (1) | AU2020301025B2 (cg-RX-API-DMAC10.html) |
| CA (1) | CA3144106A1 (cg-RX-API-DMAC10.html) |
| IL (1) | IL289421A (cg-RX-API-DMAC10.html) |
| WO (1) | WO2021003343A1 (cg-RX-API-DMAC10.html) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA3154370A1 (en) | 2019-10-24 | 2021-04-29 | Jessica WOODLEY | Modified double-stranded donor templates |
| CN119343462A (zh) | 2022-05-13 | 2025-01-21 | 合成Dna技术公司 | 使用独特分子标识符改善长读测序的准确性和crispr编辑的表征 |
| US20260049352A1 (en) | 2024-08-14 | 2026-02-19 | Integrated Dna Technologies, Inc. | Adaptered-tag blocking oligonucleotides |
Family Cites Families (29)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9809904B2 (en) | 2011-04-21 | 2017-11-07 | University Of Washington Through Its Center For Commercialization | Methods for retrieval of sequence-verified DNA constructs |
| CN105531375B (zh) | 2012-12-10 | 2020-03-03 | 分析生物科学有限公司 | 靶向基因组分析的方法 |
| AU2013381709A1 (en) | 2013-03-15 | 2015-10-01 | Integrated Dna Technologies, Inc. | RNase H-based assays utilizing modified RNA monomers |
| US11306328B2 (en) | 2013-07-26 | 2022-04-19 | President And Fellows Of Harvard College | Genome engineering |
| WO2015113063A1 (en) * | 2014-01-27 | 2015-07-30 | Georgia Tech Research Corporation | Methods and systems for identifying crispr/cas off-target sites |
| AU2015280069B2 (en) | 2014-06-23 | 2021-08-12 | The General Hospital Corporation | Genomewide unbiased identification of dsbs evaluated by sequencing (guide-seq) |
| WO2016030899A1 (en) | 2014-08-28 | 2016-03-03 | Yeda Research And Development Co. Ltd. | Methods of treating amyotrophic lateral scleroses |
| WO2016081798A1 (en) | 2014-11-20 | 2016-05-26 | Children's Medical Center Corporation | Methods relating to the detection of recurrent and non-specific double strand breaks in the genome |
| EP3234192B1 (en) * | 2014-12-19 | 2021-07-14 | The Broad Institute, Inc. | Unbiased identification of double-strand breaks and genomic rearrangement by genome-wide insert capture sequencing |
| EP3262189B1 (en) | 2015-02-27 | 2021-12-08 | Becton, Dickinson and Company | Methods for barcoding nucleic acids for sequencing |
| US9790490B2 (en) | 2015-06-18 | 2017-10-17 | The Broad Institute Inc. | CRISPR enzymes and systems |
| CA2989445A1 (en) | 2015-06-22 | 2016-12-29 | Mcmaster University | Biosensor comprising tandem reactions of structure switching, nucleolytic digestion and amplification of a nucleic acid assembly |
| US10526590B2 (en) | 2015-08-31 | 2020-01-07 | Agilent Technologies, Inc. | Compounds and methods for CRISPR/Cas-based genome editing by homologous recombination |
| US20170081679A1 (en) | 2015-09-22 | 2017-03-23 | Jie Xu | Methods of improving nuclease mediated homologous recombination |
| JP7011590B2 (ja) | 2015-10-12 | 2022-02-10 | イー・アイ・デュポン・ドウ・ヌムール・アンド・カンパニー | 細胞内での遺伝子組換えおよび相同組換えの増加のための保護dna鋳型および使用方法 |
| CN116814590A (zh) | 2015-10-22 | 2023-09-29 | 布罗德研究所有限公司 | Vi-b型crispr酶和系统 |
| US20170145486A1 (en) | 2015-11-25 | 2017-05-25 | Integrated Dna Technologies, Inc. | Methods for variant detection |
| GB201602473D0 (en) | 2016-02-11 | 2016-03-30 | Horizon Discovery Ltd | Replicative transposon system |
| US11810649B2 (en) | 2016-08-17 | 2023-11-07 | The Broad Institute, Inc. | Methods for identifying novel gene editing elements |
| CN118460529A (zh) | 2016-12-20 | 2024-08-09 | 百时美施贵宝公司 | 提高细胞基因组中同源定向修复(hdr)效率的方法 |
| CN111032867A (zh) | 2017-06-16 | 2020-04-17 | 应用干细胞有限公司 | 具有提高的敲入效率的基因编辑方法 |
| US20190062736A1 (en) * | 2017-08-22 | 2019-02-28 | Board Of Regents, The University Of Texas System | In situ and in vivo analysis of chromatin interactions by biotinylated dcas9 protein |
| CN111315889A (zh) | 2017-09-08 | 2020-06-19 | 生命技术公司 | 提高同源重组的方法和其组合物 |
| WO2019110067A1 (en) | 2017-12-07 | 2019-06-13 | Aarhus Universitet | Hybrid nanoparticle |
| US12406749B2 (en) | 2017-12-15 | 2025-09-02 | The Broad Institute, Inc. | Systems and methods for predicting repair outcomes in genetic engineering |
| EP3770256A4 (en) | 2018-03-20 | 2021-12-22 | Tokyo Institute of Technology | ANTISENSE OLIGONUCLEOTIDE WITH REDUCED TOXICITY |
| WO2019246553A1 (en) * | 2018-06-21 | 2019-12-26 | Memorial Sloan Kettering Cancer Center | Compositions & methods for monitoring dna repair |
| WO2020178772A1 (en) | 2019-03-04 | 2020-09-10 | King Abdullah University Of Science And Technology | Compositions and methods of labeling nucleic acids and sequencing and analysis thereof |
| CA3154370A1 (en) | 2019-10-24 | 2021-04-29 | Jessica WOODLEY | Modified double-stranded donor templates |
-
2020
- 2020-07-02 EP EP20835024.9A patent/EP3994258A4/en active Pending
- 2020-07-02 WO PCT/US2020/040621 patent/WO2021003343A1/en not_active Ceased
- 2020-07-02 US US16/919,577 patent/US12254959B2/en active Active
- 2020-07-02 AU AU2020301025A patent/AU2020301025B2/en active Active
- 2020-07-02 CA CA3144106A patent/CA3144106A1/en active Pending
- 2020-07-02 JP JP2021577412A patent/JP7579817B2/ja active Active
-
2021
- 2021-12-27 IL IL289421A patent/IL289421A/en unknown
-
2024
- 2024-10-28 JP JP2024188978A patent/JP7898488B2/ja active Active
-
2025
- 2025-02-12 US US19/052,059 patent/US20250218536A1/en active Pending
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| US11964997B2 (en) | Methods of library construction for polynucleotide sequencing | |
| US11162094B2 (en) | Capture methodologies for circulating cell free DNA | |
| JP5680304B2 (ja) | 迅速な法医学的dna分析法 | |
| JP2010535513A (ja) | 高スループット亜硫酸水素dnaシークエンシングのための方法および組成物ならびに有用性 | |
| US20110237444A1 (en) | Methods of mapping genomic methylation patterns | |
| JP2021073252A5 (cg-RX-API-DMAC10.html) | ||
| CN107922970A (zh) | 通过单探针引物延伸的靶标富集 | |
| CN110016499A (zh) | 安全测序系统 | |
| US10253352B2 (en) | Methods for determining sequence profiles | |
| CN106912197A (zh) | 用于多重pcr的方法和组合物 | |
| JP2022160661A (ja) | 単一分子配列決定のための一本鎖環状dna鋳型の作成 | |
| JP2020526195A (ja) | ライブラリー調製方法ならびにそのための組成物および使用 | |
| US20240052342A1 (en) | Method for duplex sequencing | |
| JP2019517250A (ja) | トランスポザーゼランダムプライミング法によるdna試料の調製 | |
| EP3555316B1 (en) | Modified multiplex and multistep amplification reactions and reagents therefor | |
| WO2011063210A2 (en) | Methods of mapping genomic methylation patterns | |
| US20170175182A1 (en) | Transposase-mediated barcoding of fragmented dna | |
| JP2022551401A5 (cg-RX-API-DMAC10.html) | ||
| US20210095351A1 (en) | Methods of Preparing Dual Indexed Methyl-Seq Libraries | |
| US20180100180A1 (en) | Methods of single dna/rna molecule counting | |
| JP2022540792A (ja) | Crisprで導入された二本鎖dna切断修復の同定、特徴付けおよび定量化 | |
| KR102924534B1 (ko) | 분자 바코딩 효율을 향상시키기 위한 조성물 및 이의 용도 | |
| CA3096462C (en) | Method for detecting variation of reference sequence in target nucleic acid region | |
| CN114774514A (zh) | 一种适用于高通量靶向基因组甲基化检测的文库构建方法及其试剂盒 | |
| Żmieńko et al. | PERSPECTIVES Transcriptome sequencing: next generation approach to RNA functional analysis |