JP2022537358A - エクトヌクレオチダーゼ阻害剤およびその使用方法 - Google Patents
エクトヌクレオチダーゼ阻害剤およびその使用方法 Download PDFInfo
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- JP2022537358A JP2022537358A JP2021575365A JP2021575365A JP2022537358A JP 2022537358 A JP2022537358 A JP 2022537358A JP 2021575365 A JP2021575365 A JP 2021575365A JP 2021575365 A JP2021575365 A JP 2021575365A JP 2022537358 A JP2022537358 A JP 2022537358A
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- amino
- cancer
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- chloro
- alkyl
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- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
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- A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
- A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
- A61K31/7064—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
- A61K31/7076—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines containing purines, e.g. adenosine, adenylic acid
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- A—HUMAN NECESSITIES
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- A61P9/00—Drugs for disorders of the cardiovascular system
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- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
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Landscapes
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- Saccharide Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
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| PCT/US2020/038395 WO2020257429A1 (en) | 2019-06-20 | 2020-06-18 | Ectonucleotidase inhibitors and methods of use thereof |
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| AU2019288495B2 (en) | 2018-06-21 | 2024-02-08 | Antengene Therapeutics Limited | Ectonucleotidase inhibitors and methods of use thereof |
| US12544391B2 (en) | 2019-07-16 | 2026-02-10 | Oric Pharmaceuticals, Inc. | CD73 inhibitors |
| HUE072504T2 (hu) | 2019-10-30 | 2025-11-28 | Oric Pharmaceuticals Inc | CD73-inhibitorok |
| CN119173276A (zh) | 2022-04-13 | 2024-12-20 | 吉利德科学公司 | 用于治疗表达Trop-2的癌症的组合疗法 |
| KR102775989B1 (ko) * | 2022-11-01 | 2025-03-04 | 윤주호 | 콜치신과 메트포르민을 유효성분으로 하는 퇴행성 신경계 질환의 예방 또는 치료용 조성물 |
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| WO2015164573A1 (en) * | 2014-04-25 | 2015-10-29 | Vitae Pharmaceuticals, Inc. | Purine derivatives as cd73 inhibitors for the treatment of cancer |
| TWI767937B (zh) * | 2016-09-09 | 2022-06-21 | 美商卡利泰拉生物科技公司 | 外核苷酸酶抑制劑及其使用方法 |
| JP7138351B2 (ja) * | 2016-12-22 | 2022-09-16 | キャリセラ バイオサイエンシーズ， インコーポレイテッド | エクトヌクレオチダーゼ阻害剤およびその使用方法 |
| AU2019288495B2 (en) * | 2018-06-21 | 2024-02-08 | Antengene Therapeutics Limited | Ectonucleotidase inhibitors and methods of use thereof |
-
2020
- 2020-06-18 KR KR1020227001589A patent/KR20220024629A/ko not_active Withdrawn
- 2020-06-18 CN CN202080045115.6A patent/CN114008048A/zh active Pending
- 2020-06-18 CA CA3143496A patent/CA3143496A1/en active Pending
- 2020-06-18 AU AU2020294724A patent/AU2020294724A1/en not_active Abandoned
- 2020-06-18 JP JP2021575365A patent/JP2022537358A/ja not_active Withdrawn
- 2020-06-18 US US17/620,508 patent/US20220363709A1/en not_active Abandoned
- 2020-06-18 EP EP20826073.7A patent/EP3986894A4/en not_active Withdrawn
- 2020-06-18 WO PCT/US2020/038395 patent/WO2020257429A1/en not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| EP3986894A4 (en) | 2023-08-09 |
| CA3143496A1 (en) | 2020-12-24 |
| AU2020294724A1 (en) | 2022-01-20 |
| KR20220024629A (ko) | 2022-03-03 |
| EP3986894A1 (en) | 2022-04-27 |
| WO2020257429A1 (en) | 2020-12-24 |
| US20220363709A1 (en) | 2022-11-17 |
| CN114008048A (zh) | 2022-02-01 |
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