JP2022535577A5 - - Google Patents

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Publication number
JP2022535577A5
JP2022535577A5 JP2021572409A JP2021572409A JP2022535577A5 JP 2022535577 A5 JP2022535577 A5 JP 2022535577A5 JP 2021572409 A JP2021572409 A JP 2021572409A JP 2021572409 A JP2021572409 A JP 2021572409A JP 2022535577 A5 JP2022535577 A5 JP 2022535577A5
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JP
Japan
Prior art keywords
heterocyclyl
cancer
pharmaceutically acceptable
acceptable salt
alkyl
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JP2021572409A
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English (en)
Japanese (ja)
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JP2022535577A (ja
JP7541538B2 (ja
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Priority claimed from PCT/US2020/035891 external-priority patent/WO2020247475A1/en
Publication of JP2022535577A publication Critical patent/JP2022535577A/ja
Publication of JP2022535577A5 publication Critical patent/JP2022535577A5/ja
Application granted granted Critical
Publication of JP7541538B2 publication Critical patent/JP7541538B2/ja
Active legal-status Critical Current
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JP2021572409A 2019-06-05 2020-06-03 癌を処置するためのprc2阻害剤としてのイミダゾ[1,2-c]ピリミジン誘導体 Active JP7541538B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201962857515P 2019-06-05 2019-06-05
US62/857,515 2019-06-05
PCT/US2020/035891 WO2020247475A1 (en) 2019-06-05 2020-06-03 Imidazo[1,2-c]pyrimidine derivatives as prc2 inhibitors for treating cancer

Publications (3)

Publication Number Publication Date
JP2022535577A JP2022535577A (ja) 2022-08-09
JP2022535577A5 true JP2022535577A5 (cg-RX-API-DMAC10.html) 2023-05-08
JP7541538B2 JP7541538B2 (ja) 2024-08-28

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ID=71842807

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JP2021572409A Active JP7541538B2 (ja) 2019-06-05 2020-06-03 癌を処置するためのprc2阻害剤としてのイミダゾ[1,2-c]ピリミジン誘導体

Country Status (9)

Country Link
US (2) US12252493B2 (cg-RX-API-DMAC10.html)
EP (1) EP3980422A1 (cg-RX-API-DMAC10.html)
JP (1) JP7541538B2 (cg-RX-API-DMAC10.html)
KR (1) KR20220027933A (cg-RX-API-DMAC10.html)
CN (1) CN114269748A (cg-RX-API-DMAC10.html)
AU (1) AU2020288563A1 (cg-RX-API-DMAC10.html)
CA (1) CA3142711A1 (cg-RX-API-DMAC10.html)
IL (1) IL288529A (cg-RX-API-DMAC10.html)
WO (1) WO2020247475A1 (cg-RX-API-DMAC10.html)

Families Citing this family (10)

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DK3746446T3 (da) 2018-01-31 2022-06-27 Mirati Therapeutics Inc PRC2-inhibitorer
US12421228B2 (en) 2019-04-22 2025-09-23 Mirati Therapeutics, Inc. Naphthyridine derivatives as PRC2 inhibitors
CN114269748A (zh) 2019-06-05 2022-04-01 米拉蒂医疗股份有限公司 作为用于治疗癌症的PRC2抑制剂的咪唑并[1,2-c]嘧啶衍生物
CN114907385B (zh) * 2021-02-10 2026-07-21 上海翱路生物医药科技有限公司 氮杂芳基化合物、其制备方法及应用
TW202312995A (zh) * 2021-08-11 2023-04-01 大陸商上海青煜醫藥科技有限公司 氮雜芳基化合物、其製備方法及應用
US20240398811A1 (en) * 2021-09-24 2024-12-05 Oric Pharmaceuticals, Inc. Prc2 inhibitors for use in treating blood disorders
WO2023049723A1 (en) * 2021-09-24 2023-03-30 Oric Pharmaceuticals, Inc. Prc2 inhibitors for use in treating blood disorders
WO2024123669A1 (en) * 2022-12-05 2024-06-13 Oric Pharmaceuticals, Inc. Treatment of prostate cancer having androgen receptor variants
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EP4753714A1 (en) * 2023-08-04 2026-06-10 Oric Pharmaceuticals, Inc. Treatment of prostate cancer

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