JP2022534846A5 - - Google Patents
Info
- Publication number
- JP2022534846A5 JP2022534846A5 JP2021561906A JP2021561906A JP2022534846A5 JP 2022534846 A5 JP2022534846 A5 JP 2022534846A5 JP 2021561906 A JP2021561906 A JP 2021561906A JP 2021561906 A JP2021561906 A JP 2021561906A JP 2022534846 A5 JP2022534846 A5 JP 2022534846A5
- Authority
- JP
- Japan
- Prior art keywords
- polypeptide
- tmmp
- polypeptides
- amino acid
- linker
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2025070050A JP2025118689A (ja) | 2019-05-29 | 2025-04-22 | 多量体ｔ細胞調節性ポリペプチド及びその使用方法 |
Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201962854200P | 2019-05-29 | 2019-05-29 | |
| US62/854,200 | 2019-05-29 | ||
| US201962872048P | 2019-07-09 | 2019-07-09 | |
| US62/872,048 | 2019-07-09 | ||
| US201962901538P | 2019-09-17 | 2019-09-17 | |
| US62/901,538 | 2019-09-17 | ||
| PCT/US2020/034939 WO2020243315A1 (en) | 2019-05-29 | 2020-05-28 | Multimeric t-cell modulatory polypeptides and methods of use thereof |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2025070050A Division JP2025118689A (ja) | 2019-05-29 | 2025-04-22 | 多量体ｔ細胞調節性ポリペプチド及びその使用方法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2022534846A JP2022534846A (ja) | 2022-08-04 |
| JP2022534846A5 true JP2022534846A5 (enExample) | 2023-05-23 |
| JP7762068B2 JP7762068B2 (ja) | 2025-10-29 |
Family
ID=73552689
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021561906A Active JP7762068B2 (ja) | 2019-05-29 | 2020-05-28 | 多量体ｔ細胞調節性ポリペプチド及びその使用方法 |
| JP2025070050A Withdrawn JP2025118689A (ja) | 2019-05-29 | 2025-04-22 | 多量体ｔ細胞調節性ポリペプチド及びその使用方法 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2025070050A Withdrawn JP2025118689A (ja) | 2019-05-29 | 2025-04-22 | 多量体ｔ細胞調節性ポリペプチド及びその使用方法 |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US20220017596A1 (enExample) |
| EP (1) | EP3976084A4 (enExample) |
| JP (2) | JP7762068B2 (enExample) |
| KR (1) | KR20220015382A (enExample) |
| CN (2) | CN118852456A (enExample) |
| AU (1) | AU2020282736B2 (enExample) |
| CA (1) | CA3137463A1 (enExample) |
| IL (1) | IL287192A (enExample) |
| MX (1) | MX2021014476A (enExample) |
| WO (1) | WO2020243315A1 (enExample) |
Families Citing this family (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SG11201808552XA (en) * | 2016-05-18 | 2018-10-30 | Cue Biopharma Inc | T-cell modulatory multimeric polypeptides and methods of use thereof |
| CN110325205B (zh) | 2016-12-22 | 2023-08-15 | 库尔生物制药有限公司 | T细胞调节性多聚体多肽及其使用方法 |
| US11851471B2 (en) | 2017-01-09 | 2023-12-26 | Cue Biopharma, Inc. | T-cell modulatory multimeric polypeptides and methods of use thereof |
| KR20240005989A (ko) | 2017-03-15 | 2024-01-12 | 큐 바이오파마, 인크. | 면역 반응을 조절하는 방법 |
| WO2019051127A1 (en) | 2017-09-07 | 2019-03-14 | Cue Biopharma, Inc. | MULTIMER MODULATOR POLYPEPTIDE OF LYMPHOCYTE T HAVING CONJUGATION SITES AND METHODS OF USE THEREOF |
| WO2019139896A1 (en) | 2018-01-09 | 2019-07-18 | Cue Biopharma, Inc. | Multimeric t-cell modulatory polypeptides and methods of use thereof |
| EP3897746A4 (en) * | 2018-12-19 | 2022-10-26 | Cue Biopharma, Inc. | MULTIMERIC T LYMPHOCYTE MODULATING POLYPEPTIDES AND METHODS OF USE THEREOF |
| US12600971B2 (en) | 2019-02-13 | 2026-04-14 | Beam Therapeutics Inc. | Modified immune cells having adenosine deaminase base editors for modifying a nucleobase in a target sequence |
| US12594301B2 (en) | 2019-09-27 | 2026-04-07 | Beam Therapeutics Inc. | Compositions and methods for treatment of liquid cancers |
| WO2021081232A1 (en) * | 2019-10-23 | 2021-04-29 | Cue Biopharma, Inc. | Modified cytotoxic t cells and methods of use thereof |
| IL296209A (en) | 2020-05-12 | 2022-11-01 | Cue Biopharma Inc | Multimeric t-cell modulatory polypeptides and methods of using them |
| JP2023541366A (ja) | 2020-09-09 | 2023-10-02 | キュー バイオファーマ， インコーポレイテッド | １型真性糖尿病（ｔ１ｄ）を治療するためのｍｈｃクラスｉｉ ｔ細胞調節多量体ポリペプチド及びその使用方法 |
| US12435444B2 (en) | 2021-03-09 | 2025-10-07 | Cdr-Life Ag | Rabbit-derived antigen binding protein nucleic acid libraries and methods of making the same |
| EP4308143A4 (en) * | 2021-03-19 | 2025-06-04 | Cue Biopharma, Inc. | T-cell modulatory polypeptides and methods of use thereof |
| US20240374571A1 (en) | 2021-09-01 | 2024-11-14 | Novartis Ag | Pharmaceutical combinations comprising a tead inhibitor and uses thereof for the treatment of cancers |
| WO2023097188A1 (en) * | 2021-11-24 | 2023-06-01 | Cue Biopharma, Inc. | T-cell modulatory multimeric polypeptides and methods of use thereof |
| CA3240046A1 (en) * | 2021-12-14 | 2023-06-22 | Cdr-Life Ag | Dual mhc-targeting t cell engager |
| JP2025515575A (ja) * | 2022-04-14 | 2025-05-20 | キュー バイオファーマ， インコーポレイテッド | Ｔ細胞エンゲージングポリペプチドおよびその使用方法 |
| CN115838432B (zh) * | 2022-07-08 | 2023-12-08 | 浙江大学 | 一种靶向调控抗原特异性t细胞的融合蛋白及应用 |
| CN116063463B (zh) * | 2022-08-12 | 2025-08-01 | 辽宁成大生物股份有限公司 | 抗rHPV68 L1蛋白CD68单克隆抗体、rHPV68型蛋白抗原的检测试剂盒 |
| WO2024044750A2 (en) * | 2022-08-26 | 2024-02-29 | Beam Therapeutics Inc. | Modified allogeneic cells and methods and compositions for the preparation thereof |
| EP4587046A1 (en) | 2022-09-14 | 2025-07-23 | CDR-Life AG | Mage-a4 peptide dual t cell engagers |
Family Cites Families (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1454138B1 (en) * | 2001-12-04 | 2012-01-18 | Merck Patent GmbH | Immunocytokines with modulated selectivity |
| WO2007136778A2 (en) * | 2006-05-19 | 2007-11-29 | Teva Pharmaceutical Industries, Ltd. | Fusion proteins, uses thereof and processes for producing same |
| US20130089554A1 (en) * | 2009-12-29 | 2013-04-11 | Emergent Product Development Seattle, Llc | RON Binding Constructs and Methods of Use Thereof |
| IN2015DN01115A (enExample) * | 2012-07-13 | 2015-06-26 | Zymeworks Inc | |
| JP6475167B2 (ja) * | 2012-12-21 | 2019-02-27 | エフ．ホフマン−ラ ロシュ アーゲーＦ． Ｈｏｆｆｍａｎｎ−Ｌａ Ｒｏｃｈｅ Ａｋｔｉｅｎｇｅｓｅｌｌｓｃｈａｆｔ | ジスルフィド結合した多価ｍｈｃクラスｉを含む多機能タンパク質 |
| EP3587448B1 (en) * | 2013-03-15 | 2021-05-19 | Xencor, Inc. | Heterodimeric proteins |
| JP6652932B2 (ja) * | 2014-06-18 | 2020-02-26 | アルバート アインシュタイン カレッジ オブ メディシン | ｓｙｎＴａｃポリペプチド及びその使用 |
| IL304950A (en) * | 2015-04-10 | 2023-10-01 | Amgen Inc | Interleukin for the expansion of myotonic control T-2 cells |
| CA3014458A1 (en) * | 2016-03-02 | 2017-09-08 | Cue Biopharma, Inc. | T-cell modulatory multimeric polypeptides and methods of use thereof |
| WO2017151940A2 (en) * | 2016-03-03 | 2017-09-08 | Cue Biopharma, Inc. | T-cell modulatory multimeric polypeptides and methods of use thereof |
| SG11201808552XA (en) * | 2016-05-18 | 2018-10-30 | Cue Biopharma Inc | T-cell modulatory multimeric polypeptides and methods of use thereof |
| CN110325205B (zh) * | 2016-12-22 | 2023-08-15 | 库尔生物制药有限公司 | T细胞调节性多聚体多肽及其使用方法 |
| US11851471B2 (en) * | 2017-01-09 | 2023-12-26 | Cue Biopharma, Inc. | T-cell modulatory multimeric polypeptides and methods of use thereof |
| KR20240005989A (ko) * | 2017-03-15 | 2024-01-12 | 큐 바이오파마, 인크. | 면역 반응을 조절하는 방법 |
| US11407806B2 (en) * | 2017-04-06 | 2022-08-09 | Albert Einstein College Of Medicine | Precision activation of HIV-specific CTLS to eliminate reactivated latent T cells |
| WO2019051127A1 (en) * | 2017-09-07 | 2019-03-14 | Cue Biopharma, Inc. | MULTIMER MODULATOR POLYPEPTIDE OF LYMPHOCYTE T HAVING CONJUGATION SITES AND METHODS OF USE THEREOF |
| WO2022119958A1 (en) * | 2020-12-02 | 2022-06-09 | Cue Biopharma, Inc. | T-cell modulatory multimeric polypeptides and methods of use thereof |
-
2020
- 2020-05-28 KR KR1020217037009A patent/KR20220015382A/ko not_active Ceased
- 2020-05-28 WO PCT/US2020/034939 patent/WO2020243315A1/en not_active Ceased
- 2020-05-28 AU AU2020282736A patent/AU2020282736B2/en active Active
- 2020-05-28 CA CA3137463A patent/CA3137463A1/en active Pending
- 2020-05-28 CN CN202410806389.2A patent/CN118852456A/zh active Pending
- 2020-05-28 CN CN202080035915.XA patent/CN114126635A/zh active Pending
- 2020-05-28 EP EP20815621.6A patent/EP3976084A4/en active Pending
- 2020-05-28 MX MX2021014476A patent/MX2021014476A/es unknown
- 2020-05-28 JP JP2021561906A patent/JP7762068B2/ja active Active
-
2021
- 2021-09-30 US US17/490,516 patent/US20220017596A1/en active Pending
- 2021-10-12 IL IL287192A patent/IL287192A/en unknown
-
2025
- 2025-04-22 JP JP2025070050A patent/JP2025118689A/ja not_active Withdrawn
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