JP2022534751A5 - - Google Patents

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Publication number
JP2022534751A5
JP2022534751A5 JP2021570931A JP2021570931A JP2022534751A5 JP 2022534751 A5 JP2022534751 A5 JP 2022534751A5 JP 2021570931 A JP2021570931 A JP 2021570931A JP 2021570931 A JP2021570931 A JP 2021570931A JP 2022534751 A5 JP2022534751 A5 JP 2022534751A5
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JP
Japan
Prior art keywords
methyl
quinazoline
amine
methoxy
ethyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2021570931A
Other languages
English (en)
Japanese (ja)
Other versions
JP2022534751A (ja
JP7641917B2 (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/EP2020/064914 external-priority patent/WO2020239952A1/en
Publication of JP2022534751A publication Critical patent/JP2022534751A/ja
Publication of JP2022534751A5 publication Critical patent/JP2022534751A5/ja
Application granted granted Critical
Publication of JP7641917B2 publication Critical patent/JP7641917B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

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JP2021570931A 2019-05-31 2020-05-28 Ｐ２ｘ３阻害剤としてのアミノキナゾリン誘導体 Active JP7641917B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
EP19177604 2019-05-31
EP19177604.6 2019-05-31
EP19201168.2 2019-10-02
EP19201168 2019-10-02
PCT/EP2020/064914 WO2020239952A1 (en) 2019-05-31 2020-05-28 Amino quinazoline derivatives as p2x3 inhibitors

Publications (3)

Publication Number Publication Date
JP2022534751A JP2022534751A (ja) 2022-08-03
JP2022534751A5 true JP2022534751A5 (enExample) 2023-06-05
JP7641917B2 JP7641917B2 (ja) 2025-03-07

Family

ID=70861506

Family Applications (3)

Application Number Title Priority Date Filing Date
JP2021570930A Active JP7644029B2 (ja) 2019-05-31 2020-05-28 Ｐ２ｘ３阻害剤としてのアミノキナゾリン誘導体
JP2021570931A Active JP7641917B2 (ja) 2019-05-31 2020-05-28 Ｐ２ｘ３阻害剤としてのアミノキナゾリン誘導体
JP2025029719A Pending JP2025098014A (ja) 2019-05-31 2025-02-27 Ｐ２ｘ３阻害剤としてのアミノキナゾリン誘導体

Family Applications Before (1)

Application Number Title Priority Date Filing Date
JP2021570930A Active JP7644029B2 (ja) 2019-05-31 2020-05-28 Ｐ２ｘ３阻害剤としてのアミノキナゾリン誘導体

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2025029719A Pending JP2025098014A (ja) 2019-05-31 2025-02-27 Ｐ２ｘ３阻害剤としてのアミノキナゾリン誘導体

Country Status (20)

Country Link
US (2) US12466820B2 (enExample)
EP (2) EP3976180A1 (enExample)
JP (3) JP7644029B2 (enExample)
KR (2) KR102921974B1 (enExample)
CN (3) CN118239931A (enExample)
AU (2) AU2020281923B2 (enExample)
BR (2) BR112021021738A2 (enExample)
CA (2) CA3139019A1 (enExample)
CL (1) CL2021003165A1 (enExample)
CO (1) CO2021017031A2 (enExample)
GE (2) GEP20257823B (enExample)
IL (1) IL288405A (enExample)
MA (2) MA56022A (enExample)
MX (2) MX2021014113A (enExample)
PE (1) PE20220934A1 (enExample)
PH (1) PH12021552881A1 (enExample)
SA (1) SA521430920B1 (enExample)
SG (1) SG11202112187YA (enExample)
WO (2) WO2020239951A1 (enExample)
ZA (1) ZA202108273B (enExample)

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BR112021024108A2 (pt) 2019-05-31 2022-03-22 Ikena Oncology Inc Inibidores de tead e usos dos mesmos
MA56022A (fr) 2019-05-31 2022-04-06 Chiesi Farm Spa Dérivés d'amino quinazoline servant d'inhibiteurs de p2x3
CR20210587A (es) 2019-05-31 2022-02-11 Janssen Pharmaceutica Nv Inhibidores de molécula pequeña de quinasa inductora de nf-kb
WO2022063205A1 (zh) * 2020-09-24 2022-03-31 中国医药研究开发中心有限公司 芳基甲酰胺类化合物及其制备方法和医药用途
CA3196287A1 (en) * 2020-10-20 2022-04-28 Binhua Lv Substituted benzo or pyridopyrimidine amine inhibitor, preparation method therefor, and application thereof
WO2022112490A1 (en) * 2020-11-27 2022-06-02 Chiesi Farmaceutici S.P.A. Amino quinazoline derivatives as p2x3 inhibitors
JP2023550830A (ja) * 2020-11-27 2023-12-05 キエシ・フアルマチエウテイチ・ソチエタ・ペル・アチオニ Ｐ２ｘ３阻害剤としての（アザ）キノリン４－アミン誘導体
CN112661803A (zh) * 2020-12-17 2021-04-16 上海药明康德新药开发有限公司 DNA编码化合物库构建中On-DNA 4-胺基喹唑啉化合物的合成方法
US11673876B2 (en) 2020-12-22 2023-06-13 Mekanistic Therapeutics Llc Substituted aminobenzyl heteroaryl compounds as EGFR and/or PI3K inhibitors
CN114907284B (zh) * 2021-02-10 2023-11-03 石药集团中奇制药技术（石家庄）有限公司 一种具有抗肿瘤活性的化合物及其用途
CN115677601B (zh) * 2021-07-29 2025-06-03 石药集团中奇制药技术（石家庄）有限公司 一种具有抗肿瘤活性的化合物及其用途
WO2024235225A1 (zh) * 2023-05-15 2024-11-21 苏州泽璟生物制药股份有限公司 取代嘧啶并环类抑制剂及其制备方法和应用
JP2026517300A (ja) 2023-05-22 2026-05-28 キエシ・フアルマチエウテイチ・ソチエタ・ペル・アチオニ Ｐ２ｘ３阻害剤を調製するための方法および中間体
TW202502343A (zh) 2023-05-22 2025-01-16 義大利商吉斯藥品公司 胺基喹唑啉衍生物之鹽
KR20260109906A (ko) * 2023-11-07 2026-07-13 제노 매니지먼트, 인크. 이환 피리미딘 화합물, 이의 방법 및 용도

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MA56022A (fr) 2019-05-31 2022-04-06 Chiesi Farm Spa Dérivés d'amino quinazoline servant d'inhibiteurs de p2x3
KR102923602B1 (ko) 2019-05-31 2026-02-06 키에시 파르마슈티시 엣스. 피. 에이. P2x3 억제제로서 피리도피리미딘 유도체

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