JP2022533419A5 - - Google Patents
Info
- Publication number
- JP2022533419A5 JP2022533419A5 JP2021569112A JP2021569112A JP2022533419A5 JP 2022533419 A5 JP2022533419 A5 JP 2022533419A5 JP 2021569112 A JP2021569112 A JP 2021569112A JP 2021569112 A JP2021569112 A JP 2021569112A JP 2022533419 A5 JP2022533419 A5 JP 2022533419A5
- Authority
- JP
- Japan
- Prior art keywords
- seq
- nucleotide sequence
- nucleotide
- group
- sirna
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201910430586.8 | 2019-05-22 | ||
| CN201910430586 | 2019-05-22 | ||
| PCT/CN2020/091485 WO2020233651A1 (zh) | 2019-05-22 | 2020-05-21 | 核酸、药物组合物与缀合物及制备方法和用途 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2022533419A JP2022533419A (ja) | 2022-07-22 |
| JP2022533419A5 true JP2022533419A5 (enExample) | 2023-05-30 |
| JP7606758B2 JP7606758B2 (ja) | 2024-12-26 |
Family
ID=73458360
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021569112A Active JP7606758B2 (ja) | 2019-05-22 | 2020-05-21 | 核酸、薬物組成物及び複合体ならびに調製方法と使用 |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US20240200076A1 (enExample) |
| EP (1) | EP3974533A4 (enExample) |
| JP (1) | JP7606758B2 (enExample) |
| CN (2) | CN113614230B (enExample) |
| TW (1) | TWI863999B (enExample) |
| WO (1) | WO2020233651A1 (enExample) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| HRP20250277T1 (hr) | 2017-12-01 | 2025-05-09 | Suzhou Ribo Life Science Co., Ltd. | Dvolančani oligonukleotid, sastav i konjugat koji sadrži dvolančani oligonukleotid, postupak njihove pripreme i upotreba |
| JP7507495B2 (ja) | 2018-12-28 | 2024-06-28 | スーチョウ リボ ライフ サイエンス カンパニー、リミテッド | 核酸、当該核酸を含む組成物及び複合体ならびに調製方法と使用 |
| JP7610848B2 (ja) | 2019-05-22 | 2025-01-09 | スーチョウ リボ ライフ サイエンス カンパニー、リミテッド | 核酸、薬物組成物及び複合体ならびに調製方法と使用 |
| CN113286888B (zh) | 2019-05-22 | 2023-12-22 | 苏州瑞博生物技术股份有限公司 | 核酸、药物组合物与缀合物及制备方法和用途 |
| CN113227376B (zh) * | 2019-05-22 | 2024-04-09 | 苏州瑞博生物技术股份有限公司 | 核酸、药物组合物与缀合物及制备方法和用途 |
| CN113795582B (zh) | 2019-05-24 | 2024-05-24 | 苏州瑞博生物技术股份有限公司 | 核酸、药物组合物与缀合物及制备方法和用途 |
| CN114686482B (zh) * | 2020-12-29 | 2024-05-17 | 苏州瑞博生物技术股份有限公司 | 一种核酸、含有该核酸的药物组合物与siRNA缀合物及制备方法和用途 |
| CN113073098B (zh) * | 2021-02-20 | 2024-08-20 | 北京理工大学 | 抑制BACE1基因表达的siRNA修饰物及其应用 |
| EP4722363A1 (en) * | 2023-05-24 | 2026-04-08 | Yun Ho Bio Co., Ltd | Rnai agent for inhibiting angptl3 expression and use thereof |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN100523215C (zh) * | 2000-12-01 | 2009-08-05 | 马普科技促进协会 | 介导rna干涉的小rna分子 |
| EP2229186A2 (en) | 2007-12-04 | 2010-09-22 | Alnylam Pharmaceuticals Inc. | Carbohydrate conjugates as delivery agents for oligonucleotides |
| EP2449106B1 (en) * | 2009-07-01 | 2015-04-08 | Protiva Biotherapeutics Inc. | Compositions and methods for silencing apolipoprotein b |
| RU2012147589A (ru) * | 2010-04-09 | 2014-05-20 | Мерк Шарп Энд Домэ Корп. | Новые отдельные химические структурные единицы и способы доставки олигонуклеотидов |
| ES2702428T3 (es) * | 2010-11-15 | 2019-02-28 | Life Technologies Corp | Reactivos de transfección que contienen amina y métodos para prepararlos y usarlos |
| DK2694108T3 (en) * | 2011-04-08 | 2018-08-20 | Univ Leicester | METHODS OF TREATING DISEASES ASSOCIATED WITH MASP-2 DEPENDENT COMPLEMENT ACTIVATION |
| EP4253395A3 (en) * | 2012-08-06 | 2023-11-29 | Alnylam Pharmaceuticals, Inc. | Processes for the preparation of carbohydrate conjugated rna agents |
| PL2992098T3 (pl) | 2013-05-01 | 2019-09-30 | Ionis Pharmaceuticals, Inc. | Kompozycje i sposoby modulowania ekspresji hbv i ttr |
| JP2016528890A (ja) * | 2013-07-09 | 2016-09-23 | プレジデント アンド フェローズ オブ ハーバード カレッジ | ＣＲＩＳＰＲ／Ｃａｓ系を用いるゲノム編集の治療用の使用 |
| WO2015006740A2 (en) * | 2013-07-11 | 2015-01-15 | Alnylam Pharmaceuticals, Inc. | Oligonucleotide-ligand conjugates and process for their preparation |
| ES2738289T3 (es) * | 2013-11-06 | 2020-01-21 | Hospital Clinic Barcelona | Procedimiento para el subtipado de tipos de linfoma por medio de perfiles de expresión |
| HRP20250277T1 (hr) * | 2017-12-01 | 2025-05-09 | Suzhou Ribo Life Science Co., Ltd. | Dvolančani oligonukleotid, sastav i konjugat koji sadrži dvolančani oligonukleotid, postupak njihove pripreme i upotreba |
| WO2019105414A1 (zh) * | 2017-12-01 | 2019-06-06 | 苏州瑞博生物技术有限公司 | 一种核酸、含有该核酸的组合物与缀合物及制备方法和用途 |
| EP4372086A4 (en) * | 2021-07-16 | 2026-06-17 | Suzhou Ribo Life Science Co Ltd | DOUBLE-STRANDED OLIGONUCLEOTIDE, COMPOSITION AND CONJUGATE CONTAINING A DOUBLE-STRANDED OLIGONUCLEOTIDE, PREPARATION PROCESSES AND USES |
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2020
- 2020-05-21 CN CN202080007348.7A patent/CN113614230B/zh active Active
- 2020-05-21 CN CN202410318986.0A patent/CN118340793A/zh active Pending
- 2020-05-21 WO PCT/CN2020/091485 patent/WO2020233651A1/zh not_active Ceased
- 2020-05-21 US US17/595,620 patent/US20240200076A1/en not_active Abandoned
- 2020-05-21 JP JP2021569112A patent/JP7606758B2/ja active Active
- 2020-05-21 EP EP20810635.1A patent/EP3974533A4/en not_active Withdrawn
- 2020-05-21 TW TW109116934A patent/TWI863999B/zh active