JP2022531685A5 - - Google Patents

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Publication number
JP2022531685A5
JP2022531685A5 JP2021565869A JP2021565869A JP2022531685A5 JP 2022531685 A5 JP2022531685 A5 JP 2022531685A5 JP 2021565869 A JP2021565869 A JP 2021565869A JP 2021565869 A JP2021565869 A JP 2021565869A JP 2022531685 A5 JP2022531685 A5 JP 2022531685A5
Authority
JP
Japan
Prior art keywords
approximately
pharmaceutical composition
weight
composition according
methylnaltrexone
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2021565869A
Other languages
English (en)
Japanese (ja)
Other versions
JP7692366B2 (ja
JP2022531685A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/EP2020/062794 external-priority patent/WO2020225395A1/en
Publication of JP2022531685A publication Critical patent/JP2022531685A/ja
Publication of JP2022531685A5 publication Critical patent/JP2022531685A5/ja
Application granted granted Critical
Publication of JP7692366B2 publication Critical patent/JP7692366B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

JP2021565869A 2019-05-07 2020-05-07 メチルナルトレキソンの液体経口投与製剤 Active JP7692366B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201962844613P 2019-05-07 2019-05-07
US62/844,613 2019-05-07
US202063010528P 2020-04-15 2020-04-15
US63/010,528 2020-04-15
PCT/EP2020/062794 WO2020225395A1 (en) 2019-05-07 2020-05-07 Liquid oral dosage formulations of methylnaltrexone

Publications (3)

Publication Number Publication Date
JP2022531685A JP2022531685A (ja) 2022-07-08
JP2022531685A5 true JP2022531685A5 (enExample) 2023-05-15
JP7692366B2 JP7692366B2 (ja) 2025-06-13

Family

ID=70802839

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2021565869A Active JP7692366B2 (ja) 2019-05-07 2020-05-07 メチルナルトレキソンの液体経口投与製剤

Country Status (9)

Country Link
US (1) US20220096461A1 (enExample)
EP (1) EP3965731A1 (enExample)
JP (1) JP7692366B2 (enExample)
CN (1) CN113747882A (enExample)
AU (1) AU2020268767B8 (enExample)
BR (1) BR112021022194A2 (enExample)
CA (1) CA3137488C (enExample)
MX (1) MX2021013488A (enExample)
WO (1) WO2020225395A1 (enExample)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI489984B (zh) 2006-08-04 2015-07-01 Wyeth Corp 用於非經腸道傳輸化合物之配方及其用途
WO2021224138A1 (en) 2020-05-02 2021-11-11 Bausch Health Ireland Limited Methods of reducing mortality risk in subjects suffering from an underlying disease or condition by administration of methylnaltrexone
AU2022248850A1 (en) * 2021-03-27 2023-11-09 TRx Biosciences Limited Compositions having improved bioavailability of therapeutics
WO2025177181A1 (en) * 2024-02-19 2025-08-28 Nanoprime Labs Corp Self-assembling microemulsions carrying nutraceuticals and methods for use thereof

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4518433A (en) 1982-11-08 1985-05-21 Fmc Corporation Enteric coating for pharmaceutical dosage forms
US4719215A (en) 1986-03-07 1988-01-12 University Of Chicago Quaternary derivatives of noroxymorphone which relieve nausea and emesis
US4861781A (en) 1986-03-07 1989-08-29 The University Of Chicago Quaternary derivatives of noroxymorphone which relieve nausea and emesis
US4816259A (en) 1987-02-12 1989-03-28 Chase Chemical Company, L.P. Process for coating gelatin capsules
US5102887A (en) 1989-02-17 1992-04-07 Arch Development Corporation Method for reducing emesis and nausea induced by the administration of an emesis causing agent
US5330759A (en) 1992-08-26 1994-07-19 Sterling Winthrop Inc. Enteric coated soft capsules and method of preparation thereof
DE19651551C2 (de) 1996-12-11 2000-02-03 Klinge Co Chem Pharm Fab Opioidantagonisthaltige galenische Formulierung
US5972954A (en) 1997-11-03 1999-10-26 Arch Development Corporation Use of methylnaltrexone and related compounds
US6559158B1 (en) 1997-11-03 2003-05-06 Ur Labs, Inc. Use of methylnaltrexone and related compounds to treat chronic opioid use side affects
US6274591B1 (en) 1997-11-03 2001-08-14 Joseph F. Foss Use of methylnaltrexone and related compounds
CN1688294A (zh) 2002-10-01 2005-10-26 旗帜药物胶囊公司 用于制备软胶囊壁的肠溶组合物
MXPA05010821A (es) 2003-04-08 2006-03-30 Progenics Pharm Inc Terapia de combinacion para constipacion que comprende un laxante y un antagonista opioide periferico.
JP2006522817A (ja) 2003-04-08 2006-10-05 プロジェニックス ファーマシューティカルズ,インコーポレーテッド 過敏性腸症候群を処置するための末梢オピオイドアンタゴニスト、特にメチルナルトレキソンの使用
US8946262B2 (en) 2003-12-04 2015-02-03 Adolor Corporation Methods of preventing and treating gastrointestinal dysfunction
AR057035A1 (es) 2005-05-25 2007-11-14 Progenics Pharm Inc SíNTESIS DE (R)-N-METILNALTREXONA, COMPOSICIONES FARMACÉUTICAS Y USOS
TWI605814B (zh) * 2010-03-11 2017-11-21 惠氏有限責任公司 甲基拿淬松(methylnaltrexone)之口服製劑及親脂性鹽
JP6397813B2 (ja) 2012-05-02 2018-09-26 キャプシュゲル・ベルジウム・エヌ・ヴィ ヒドロキシプロピルメチルセルロースアセテートスクシネート(hpmcas)の水性分散液
US10485798B2 (en) * 2012-08-22 2019-11-26 Aptapharma Inc. Methylnaltrexone nasal formulations, methods of making, and use thereof
EP3206491B1 (en) * 2014-10-17 2019-11-27 Salix Pharmaceuticals, Inc. Use of methylnaltrexone to attenuate tumor progression

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