JP2022528024A5 - - Google Patents

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Publication number
JP2022528024A5
JP2022528024A5 JP2021525181A JP2021525181A JP2022528024A5 JP 2022528024 A5 JP2022528024 A5 JP 2022528024A5 JP 2021525181 A JP2021525181 A JP 2021525181A JP 2021525181 A JP2021525181 A JP 2021525181A JP 2022528024 A5 JP2022528024 A5 JP 2022528024A5
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JP
Japan
Prior art keywords
antigen
tumor
cells
binding domain
tag
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JP2021525181A
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English (en)
Japanese (ja)
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JP7674243B2 (ja
JP2022528024A (ja
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Priority claimed from PCT/AU2019/051189 external-priority patent/WO2020087116A1/en
Publication of JP2022528024A publication Critical patent/JP2022528024A/ja
Publication of JP2022528024A5 publication Critical patent/JP2022528024A5/ja
Priority to JP2025072427A priority Critical patent/JP2025129148A/ja
Application granted granted Critical
Publication of JP7674243B2 publication Critical patent/JP7674243B2/ja
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JP2021525181A 2018-10-30 2019-10-29 Carを発現する免疫細胞に抗原提示細胞を係合させるための二重特異性ポリペプチド及びそれらの使用 Active JP7674243B2 (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2025072427A JP2025129148A (ja) 2018-10-30 2025-04-24 Carを発現する免疫細胞に抗原提示細胞を係合させるための二重特異性ポリペプチド及びそれらの使用

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
AU2018904117A AU2018904117A0 (en) 2018-10-30 Polypeptides and uses thereof
AU2018904117 2018-10-30
AU2019903255 2019-09-04
AU2019903255A AU2019903255A0 (en) 2019-09-04 Polypeptides and uses thereof
PCT/AU2019/051189 WO2020087116A1 (en) 2018-10-30 2019-10-29 Bispecific polypeptides for engagement of car expressing immune cells with antigen presenting cells and uses thereof

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2025072427A Division JP2025129148A (ja) 2018-10-30 2025-04-24 Carを発現する免疫細胞に抗原提示細胞を係合させるための二重特異性ポリペプチド及びそれらの使用

Publications (3)

Publication Number Publication Date
JP2022528024A JP2022528024A (ja) 2022-06-08
JP2022528024A5 true JP2022528024A5 (https=) 2022-11-10
JP7674243B2 JP7674243B2 (ja) 2025-05-09

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ID=70461795

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2021525181A Active JP7674243B2 (ja) 2018-10-30 2019-10-29 Carを発現する免疫細胞に抗原提示細胞を係合させるための二重特異性ポリペプチド及びそれらの使用
JP2025072427A Pending JP2025129148A (ja) 2018-10-30 2025-04-24 Carを発現する免疫細胞に抗原提示細胞を係合させるための二重特異性ポリペプチド及びそれらの使用

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2025072427A Pending JP2025129148A (ja) 2018-10-30 2025-04-24 Carを発現する免疫細胞に抗原提示細胞を係合させるための二重特異性ポリペプチド及びそれらの使用

Country Status (8)

Country Link
US (2) US11866504B2 (https=)
EP (1) EP3877417A4 (https=)
JP (2) JP7674243B2 (https=)
CN (1) CN113195535A (https=)
AU (2) AU2019370618C1 (https=)
CA (1) CA3117079A1 (https=)
SG (1) SG11202104180WA (https=)
WO (1) WO2020087116A1 (https=)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP7846667B2 (ja) 2020-07-16 2026-04-15 レジェンド バイオテック アイルランド リミテッド Cd20結合分子及びその使用
IL299865A (en) * 2020-07-16 2023-03-01 Nanjing Legend Biotech Co Ltd Multispecific chimeric antigen receptors and uses thereof
AU2023347073A1 (en) * 2022-09-20 2025-01-02 Currus Biologics Pty Ltd Anti-flag antibodies
KR20250071228A (ko) * 2022-09-20 2025-05-21 커러스 바이오로직스 피티와이 엘티디 고갈된 면역 세포를 구제하는 방법
AU2023347072A1 (en) * 2022-09-20 2025-01-02 Currus Biologics Pty Ltd Bispecific polypeptides and uses thereof

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2990416B1 (en) * 2014-08-29 2018-06-20 GEMoaB Monoclonals GmbH Universal chimeric antigen receptor expressing immune cells for targeting of diverse multiple antigens and method of manufacturing the same and use of the same for treatment of cancer, infections and autoimmune disorders
CN104829730A (zh) * 2015-04-14 2015-08-12 苏静 一种能联合免疫细胞增强肿瘤杀伤能力的双特异性抗体及其制备方法和应用
EP3295171A1 (en) * 2015-05-12 2018-03-21 INSERM - Institut National de la Santé et de la Recherche Médicale Methods and kits for labeling, detection and isolation of foxp3+ regulatory t cells, isolated population of foxp3+ regulatory t cells thus obtained and uses thereof
WO2017167350A1 (en) * 2016-03-30 2017-10-05 Horst Lindhofer Multispecific antibodies for use in the treatment of a neoplasm of the urinary tract
CA3021634A1 (en) * 2016-04-15 2017-10-19 Zymeworks Inc. Multi-specific antigen-binding constructs targeting immunotherapeutics
CN107417792B (zh) * 2017-08-29 2020-07-03 天津医科大学总医院 抗cd40-her2双特异性单链抗体及其在制备抗肿瘤药物中的应用
CN113286811B (zh) * 2018-07-30 2024-12-06 南加利福尼亚大学 改善过继性细胞疗法的效力和安全性

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