AU2019370618C1 - Bispecific polypeptides for engagement of CAR expressing immune cells with antigen presenting cells and uses thereof - Google Patents
Bispecific polypeptides for engagement of CAR expressing immune cells with antigen presenting cells and uses thereof Download PDFInfo
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- AU2019370618C1 AU2019370618C1 AU2019370618A AU2019370618A AU2019370618C1 AU 2019370618 C1 AU2019370618 C1 AU 2019370618C1 AU 2019370618 A AU2019370618 A AU 2019370618A AU 2019370618 A AU2019370618 A AU 2019370618A AU 2019370618 C1 AU2019370618 C1 AU 2019370618C1
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- A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
- A61K39/39541—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against normal tissues, cells
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- A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
- A61K39/3955—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
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- A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
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- C—CHEMISTRY; METALLURGY
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- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
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- C07K2319/00—Fusion polypeptide
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- C07K2319/33—Fusion polypeptide fusions for targeting to specific cell types, e.g. tissue specific targeting, targeting of a bacterial subspecies
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Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| AU2022263573A AU2022263573B2 (en) | 2018-10-30 | 2022-11-04 | Bispecific polypeptides for engagement of CAR expressing immune cells with antigen presenting cells and uses thereof |
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| AU2018904117A AU2018904117A0 (en) | 2018-10-30 | Polypeptides and uses thereof | |
| AU2018904117 | 2018-10-30 | ||
| AU2019903255 | 2019-09-04 | ||
| AU2019903255A AU2019903255A0 (en) | 2019-09-04 | Polypeptides and uses thereof | |
| PCT/AU2019/051189 WO2020087116A1 (en) | 2018-10-30 | 2019-10-29 | Bispecific polypeptides for engagement of car expressing immune cells with antigen presenting cells and uses thereof |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU2022263573A Division AU2022263573B2 (en) | 2018-10-30 | 2022-11-04 | Bispecific polypeptides for engagement of CAR expressing immune cells with antigen presenting cells and uses thereof |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| AU2019370618A1 AU2019370618A1 (en) | 2021-06-03 |
| AU2019370618B2 AU2019370618B2 (en) | 2022-08-11 |
| AU2019370618C1 true AU2019370618C1 (en) | 2023-02-09 |
Family
ID=70461795
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU2019370618A Active AU2019370618C1 (en) | 2018-10-30 | 2019-10-29 | Bispecific polypeptides for engagement of CAR expressing immune cells with antigen presenting cells and uses thereof |
| AU2022263573A Active AU2022263573B2 (en) | 2018-10-30 | 2022-11-04 | Bispecific polypeptides for engagement of CAR expressing immune cells with antigen presenting cells and uses thereof |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU2022263573A Active AU2022263573B2 (en) | 2018-10-30 | 2022-11-04 | Bispecific polypeptides for engagement of CAR expressing immune cells with antigen presenting cells and uses thereof |
Country Status (8)
| Country | Link |
|---|---|
| US (2) | US11866504B2 (https=) |
| EP (1) | EP3877417A4 (https=) |
| JP (2) | JP7674243B2 (https=) |
| CN (1) | CN113195535A (https=) |
| AU (2) | AU2019370618C1 (https=) |
| CA (1) | CA3117079A1 (https=) |
| SG (1) | SG11202104180WA (https=) |
| WO (1) | WO2020087116A1 (https=) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP7846667B2 (ja) | 2020-07-16 | 2026-04-15 | レジェンド バイオテック アイルランド リミテッド | Cd20結合分子及びその使用 |
| IL299865A (en) * | 2020-07-16 | 2023-03-01 | Nanjing Legend Biotech Co Ltd | Multispecific chimeric antigen receptors and uses thereof |
| AU2023347073A1 (en) * | 2022-09-20 | 2025-01-02 | Currus Biologics Pty Ltd | Anti-flag antibodies |
| KR20250071228A (ko) * | 2022-09-20 | 2025-05-21 | 커러스 바이오로직스 피티와이 엘티디 | 고갈된 면역 세포를 구제하는 방법 |
| AU2023347072A1 (en) * | 2022-09-20 | 2025-01-02 | Currus Biologics Pty Ltd | Bispecific polypeptides and uses thereof |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2016180948A1 (en) * | 2015-05-12 | 2016-11-17 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Methods and kits for labeling, detection and isolation of foxp3+ regulatory t cells, isolated population of foxp3+ regulatory t cells thus obtained and uses thereof |
| WO2017167919A1 (en) * | 2016-03-30 | 2017-10-05 | Horst Lindhofer | Multispecific antibodies for use in the treatment of a neoplasm of the urinary tract |
| WO2017177337A1 (en) * | 2016-04-15 | 2017-10-19 | Zymeworks Inc. | Multi-specific antigen-binding constructs targeting immunotherapeutics |
| US20180021440A1 (en) * | 2015-04-14 | 2018-01-25 | Benhealth Biopharmaceutic (Shenzhen) Co., Ltd. | Bispecific antibody capable of being combined with immune cells to enhance tumor killing capability, and preparation method therefor and application thereof |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2990416B1 (en) * | 2014-08-29 | 2018-06-20 | GEMoaB Monoclonals GmbH | Universal chimeric antigen receptor expressing immune cells for targeting of diverse multiple antigens and method of manufacturing the same and use of the same for treatment of cancer, infections and autoimmune disorders |
| CN107417792B (zh) * | 2017-08-29 | 2020-07-03 | 天津医科大学总医院 | 抗cd40-her2双特异性单链抗体及其在制备抗肿瘤药物中的应用 |
| CN113286811B (zh) * | 2018-07-30 | 2024-12-06 | 南加利福尼亚大学 | 改善过继性细胞疗法的效力和安全性 |
-
2019
- 2019-10-29 SG SG11202104180WA patent/SG11202104180WA/en unknown
- 2019-10-29 AU AU2019370618A patent/AU2019370618C1/en active Active
- 2019-10-29 JP JP2021525181A patent/JP7674243B2/ja active Active
- 2019-10-29 CN CN201980075175.XA patent/CN113195535A/zh active Pending
- 2019-10-29 CA CA3117079A patent/CA3117079A1/en active Pending
- 2019-10-29 EP EP19879319.2A patent/EP3877417A4/en active Pending
- 2019-10-29 WO PCT/AU2019/051189 patent/WO2020087116A1/en not_active Ceased
- 2019-10-29 US US17/289,997 patent/US11866504B2/en active Active
-
2022
- 2022-11-04 AU AU2022263573A patent/AU2022263573B2/en active Active
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2023
- 2023-11-13 US US18/507,157 patent/US20240150482A1/en active Pending
-
2025
- 2025-04-24 JP JP2025072427A patent/JP2025129148A/ja active Pending
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20180021440A1 (en) * | 2015-04-14 | 2018-01-25 | Benhealth Biopharmaceutic (Shenzhen) Co., Ltd. | Bispecific antibody capable of being combined with immune cells to enhance tumor killing capability, and preparation method therefor and application thereof |
| WO2016180948A1 (en) * | 2015-05-12 | 2016-11-17 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Methods and kits for labeling, detection and isolation of foxp3+ regulatory t cells, isolated population of foxp3+ regulatory t cells thus obtained and uses thereof |
| WO2017167919A1 (en) * | 2016-03-30 | 2017-10-05 | Horst Lindhofer | Multispecific antibodies for use in the treatment of a neoplasm of the urinary tract |
| WO2017177337A1 (en) * | 2016-04-15 | 2017-10-19 | Zymeworks Inc. | Multi-specific antigen-binding constructs targeting immunotherapeutics |
Non-Patent Citations (4)
| Title |
|---|
| Haneen Shalabi et al "Case report: Impact of BITE on CAR-T cell expansion", Advances in Cell and Gene Therapy, (2019-02-04), vol. 2, no. 3, doi:10.1002/acg2.50, ISSN 2573-8461, pages 1 - 4 * |
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Also Published As
| Publication number | Publication date |
|---|---|
| US20220017628A1 (en) | 2022-01-20 |
| US11866504B2 (en) | 2024-01-09 |
| US20240150482A1 (en) | 2024-05-09 |
| AU2022263573B2 (en) | 2025-04-10 |
| WO2020087116A1 (en) | 2020-05-07 |
| KR20210108361A (ko) | 2021-09-02 |
| EP3877417A1 (en) | 2021-09-15 |
| JP2025129148A (ja) | 2025-09-04 |
| AU2019370618A1 (en) | 2021-06-03 |
| EP3877417A4 (en) | 2022-08-03 |
| JP7674243B2 (ja) | 2025-05-09 |
| CN113195535A (zh) | 2021-07-30 |
| AU2022263573A1 (en) | 2022-12-08 |
| AU2019370618B2 (en) | 2022-08-11 |
| SG11202104180WA (en) | 2021-05-28 |
| JP2022528024A (ja) | 2022-06-08 |
| CA3117079A1 (en) | 2020-05-07 |
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