CN113195535A - 用于连接表达car的免疫细胞与抗原呈递细胞的双特异性多肽及其用途 - Google Patents

用于连接表达car的免疫细胞与抗原呈递细胞的双特异性多肽及其用途 Download PDF

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Publication number
CN113195535A
CN113195535A CN201980075175.XA CN201980075175A CN113195535A CN 113195535 A CN113195535 A CN 113195535A CN 201980075175 A CN201980075175 A CN 201980075175A CN 113195535 A CN113195535 A CN 113195535A
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M·克肖
C·斯莱尼
B·冯谢德
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Peter Mccallum Cancer Institute
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Peter Mccallum Cancer Institute
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    • C07K16/2878Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the NGF-receptor/TNF-receptor superfamily, e.g. CD27, CD30, CD40, CD95
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CN201980075175.XA 2018-10-30 2019-10-29 用于连接表达car的免疫细胞与抗原呈递细胞的双特异性多肽及其用途 Pending CN113195535A (zh)

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Application Number Priority Date Filing Date Title
AU2018904117A AU2018904117A0 (en) 2018-10-30 Polypeptides and uses thereof
AU2018904117 2018-10-30
AU2019903255 2019-09-04
AU2019903255A AU2019903255A0 (en) 2019-09-04 Polypeptides and uses thereof
PCT/AU2019/051189 WO2020087116A1 (en) 2018-10-30 2019-10-29 Bispecific polypeptides for engagement of car expressing immune cells with antigen presenting cells and uses thereof

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CN113195535A true CN113195535A (zh) 2021-07-30

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CN201980075175.XA Pending CN113195535A (zh) 2018-10-30 2019-10-29 用于连接表达car的免疫细胞与抗原呈递细胞的双特异性多肽及其用途

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US (2) US11866504B2 (https=)
EP (1) EP3877417A4 (https=)
JP (2) JP7674243B2 (https=)
CN (1) CN113195535A (https=)
AU (2) AU2019370618C1 (https=)
CA (1) CA3117079A1 (https=)
SG (1) SG11202104180WA (https=)
WO (1) WO2020087116A1 (https=)

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JP7846667B2 (ja) 2020-07-16 2026-04-15 レジェンド バイオテック アイルランド リミテッド Cd20結合分子及びその使用
IL299865A (en) * 2020-07-16 2023-03-01 Nanjing Legend Biotech Co Ltd Multispecific chimeric antigen receptors and uses thereof
AU2023347073A1 (en) * 2022-09-20 2025-01-02 Currus Biologics Pty Ltd Anti-flag antibodies
KR20250071228A (ko) * 2022-09-20 2025-05-21 커러스 바이오로직스 피티와이 엘티디 고갈된 면역 세포를 구제하는 방법
AU2023347072A1 (en) * 2022-09-20 2025-01-02 Currus Biologics Pty Ltd Bispecific polypeptides and uses thereof

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CN106574272A (zh) * 2014-08-29 2017-04-19 哥莫阿波单克隆有限责任公司 靶向多样的多种抗原的通用嵌合抗原受体表达性免疫细胞及其制造方法及其在癌症、感染和自身免疫病的治疗中的应用
WO2017167919A1 (en) * 2016-03-30 2017-10-05 Horst Lindhofer Multispecific antibodies for use in the treatment of a neoplasm of the urinary tract
WO2017177337A1 (en) * 2016-04-15 2017-10-19 Zymeworks Inc. Multi-specific antigen-binding constructs targeting immunotherapeutics
US20180021440A1 (en) * 2015-04-14 2018-01-25 Benhealth Biopharmaceutic (Shenzhen) Co., Ltd. Bispecific antibody capable of being combined with immune cells to enhance tumor killing capability, and preparation method therefor and application thereof

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CN107417792B (zh) * 2017-08-29 2020-07-03 天津医科大学总医院 抗cd40-her2双特异性单链抗体及其在制备抗肿瘤药物中的应用
CN113286811B (zh) * 2018-07-30 2024-12-06 南加利福尼亚大学 改善过继性细胞疗法的效力和安全性

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CN106574272A (zh) * 2014-08-29 2017-04-19 哥莫阿波单克隆有限责任公司 靶向多样的多种抗原的通用嵌合抗原受体表达性免疫细胞及其制造方法及其在癌症、感染和自身免疫病的治疗中的应用
US20180021440A1 (en) * 2015-04-14 2018-01-25 Benhealth Biopharmaceutic (Shenzhen) Co., Ltd. Bispecific antibody capable of being combined with immune cells to enhance tumor killing capability, and preparation method therefor and application thereof
WO2017167919A1 (en) * 2016-03-30 2017-10-05 Horst Lindhofer Multispecific antibodies for use in the treatment of a neoplasm of the urinary tract
WO2017177337A1 (en) * 2016-04-15 2017-10-19 Zymeworks Inc. Multi-specific antigen-binding constructs targeting immunotherapeutics

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陆礼: "抗CD40 x HER2双特异性单链抗体的构建及抑制肿瘤增殖的实验", 中国博士学位论文全文数据库医药卫生科技辑, no. 01, 15 January 2018 (2018-01-15) *

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US20220017628A1 (en) 2022-01-20
US11866504B2 (en) 2024-01-09
US20240150482A1 (en) 2024-05-09
AU2022263573B2 (en) 2025-04-10
AU2019370618C1 (en) 2023-02-09
WO2020087116A1 (en) 2020-05-07
KR20210108361A (ko) 2021-09-02
EP3877417A1 (en) 2021-09-15
JP2025129148A (ja) 2025-09-04
AU2019370618A1 (en) 2021-06-03
EP3877417A4 (en) 2022-08-03
JP7674243B2 (ja) 2025-05-09
AU2022263573A1 (en) 2022-12-08
AU2019370618B2 (en) 2022-08-11
SG11202104180WA (en) 2021-05-28
JP2022528024A (ja) 2022-06-08
CA3117079A1 (en) 2020-05-07

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