JP2022527025A5 - - Google Patents

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Publication number
JP2022527025A5
JP2022527025A5 JP2021560413A JP2021560413A JP2022527025A5 JP 2022527025 A5 JP2022527025 A5 JP 2022527025A5 JP 2021560413 A JP2021560413 A JP 2021560413A JP 2021560413 A JP2021560413 A JP 2021560413A JP 2022527025 A5 JP2022527025 A5 JP 2022527025A5
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JP
Japan
Prior art keywords
alkyl
administration
compound according
formula
pharmaceutical composition
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2021560413A
Other languages
English (en)
Japanese (ja)
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JP2022527025A (ja
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Publication date
Application filed filed Critical
Priority claimed from PCT/US2020/026732 external-priority patent/WO2020206363A1/en
Publication of JP2022527025A publication Critical patent/JP2022527025A/ja
Publication of JP2022527025A5 publication Critical patent/JP2022527025A5/ja
Pending legal-status Critical Current

Links

JP2021560413A 2019-04-03 2020-04-03 神経変性疾患及びミトコンドリア病の治療のための組成物及びその使用方法 Pending JP2022527025A (ja)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US201962828995P 2019-04-03 2019-04-03
US62/828,995 2019-04-03
US201962879794P 2019-07-29 2019-07-29
US62/879,794 2019-07-29
US201962933632P 2019-11-11 2019-11-11
US62/933,632 2019-11-11
PCT/US2020/026732 WO2020206363A1 (en) 2019-04-03 2020-04-03 Compositions and methods of using the same for treatment of neurodegenerative and mitochondrial disease

Publications (2)

Publication Number Publication Date
JP2022527025A JP2022527025A (ja) 2022-05-27
JP2022527025A5 true JP2022527025A5 (enExample) 2023-04-17

Family

ID=72666280

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2021560413A Pending JP2022527025A (ja) 2019-04-03 2020-04-03 神経変性疾患及びミトコンドリア病の治療のための組成物及びその使用方法

Country Status (11)

Country Link
US (2) US20220162215A1 (enExample)
EP (1) EP3947390A4 (enExample)
JP (1) JP2022527025A (enExample)
KR (1) KR20220004068A (enExample)
CN (1) CN114026093A (enExample)
AU (1) AU2020253561A1 (enExample)
BR (1) BR112021019802A2 (enExample)
CA (1) CA3135755A1 (enExample)
IL (1) IL286767A (enExample)
MX (1) MX2021012129A (enExample)
WO (1) WO2020206363A1 (enExample)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2018237145A1 (en) 2017-06-21 2018-12-27 Mitokinin, Inc. Compositions and methods using the same for treatment of neurodegenerative and mitochondrial disease
WO2023023671A1 (en) * 2021-08-20 2023-02-23 Mitokinin, Inc. Compositions and methods for treatment of neurodegenerative and mitochondrial disease
WO2023023670A1 (en) * 2021-08-20 2023-02-23 Mitokinin, Inc. Compositions and methods of using the same for treatment of neurodegenerative and mitochondrial disease
WO2024040266A2 (en) * 2022-08-19 2024-02-22 Mitokinin, Inc. Disubstituted benzoimidazole and indole analogs as modulators of pink1
EP4620957A1 (en) * 2024-03-22 2025-09-24 Eberhard Karls Universität Tübingen Imidazo[4,5-b]pyridin-7-amine compounds binding aurora kinase a and uses thereof
CN118290348A (zh) * 2024-03-22 2024-07-05 诚达药业股份有限公司 一种4-氯吡咯并嘧啶类化合物或其衍生物的合成方法

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9613021D0 (en) * 1996-06-21 1996-08-28 Pharmacia Spa Bicyclic 4-aralkylaminopyrimidine derivatives as tyrosine kinase inhibitors
CN101316853B (zh) * 2005-08-04 2014-09-24 西特里斯药业公司 作为sirtuin调节剂的苯并噻唑和噻唑并吡啶
ES2412384T3 (es) * 2006-07-18 2013-07-11 Astellas Pharma Inc. Derivado de aminoindano o sal del mismo
AU2014214561C1 (en) * 2013-02-11 2019-01-17 Mitokinin, Inc. Compositions and methods for treating neurodegenerative diseases
EP2818472A1 (en) * 2013-06-27 2014-12-31 Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. Imidazo[4,5-c]pyridine and pyrrolo[3,2-c]pyridine compounds as G-protein-coupled receptor kinase 5 (GRK5) modulators
ES2919024T3 (es) * 2014-02-11 2022-07-21 Mitokinin Inc Composiciones y procedimientos que utilizan las mismas para el tratamiento de enfermedades neurodegenerativas y mitocondriales
CN108934162A (zh) * 2015-12-16 2018-12-04 南方研究所 吡咯并嘧啶化合物、作为激酶lrrk2抑制剂的用途及其制备方法
WO2018065365A1 (en) * 2016-10-03 2018-04-12 Janssen Pharmaceutica Nv Novel monocyclic and bicyclic ring system substituted carbanucleoside analogues for use as prmt5 inhibitors
WO2018106818A1 (en) * 2016-12-07 2018-06-14 Kura Oncology, Inc. Methods of promoting beta cell proliferation
WO2018237145A1 (en) * 2017-06-21 2018-12-27 Mitokinin, Inc. Compositions and methods using the same for treatment of neurodegenerative and mitochondrial disease
KR20220158290A (ko) * 2020-02-21 2022-11-30 미토키닌, 인크. 신경퇴행성 및 미토콘드리아 질환의 치료를 위한 조성물 및 이를 사용하는 방법

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