JP2022523047A5 - - Google Patents

Info

Publication number
JP2022523047A5
JP2022523047A5 JP2021543183A JP2021543183A JP2022523047A5 JP 2022523047 A5 JP2022523047 A5 JP 2022523047A5 JP 2021543183 A JP2021543183 A JP 2021543183A JP 2021543183 A JP2021543183 A JP 2021543183A JP 2022523047 A5 JP2022523047 A5 JP 2022523047A5
Authority
JP
Japan
Prior art keywords
sequence number
human
antigen
antibody
cdr1
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2021543183A
Other languages
English (en)
Japanese (ja)
Other versions
JP2022523047A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/EP2020/051667 external-priority patent/WO2020152290A1/en
Publication of JP2022523047A publication Critical patent/JP2022523047A/ja
Publication of JP2022523047A5 publication Critical patent/JP2022523047A5/ja
Pending legal-status Critical Current

Links

JP2021543183A 2019-01-23 2020-01-23 Cd31競合剤およびその使用 Pending JP2022523047A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP19305086 2019-01-23
EP19305086.1 2019-01-23
PCT/EP2020/051667 WO2020152290A1 (en) 2019-01-23 2020-01-23 Cd31 competitors and uses thereof

Publications (2)

Publication Number Publication Date
JP2022523047A JP2022523047A (ja) 2022-04-21
JP2022523047A5 true JP2022523047A5 (https=) 2023-02-01

Family

ID=65409014

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2021543183A Pending JP2022523047A (ja) 2019-01-23 2020-01-23 Cd31競合剤およびその使用

Country Status (13)

Country Link
US (1) US20220089765A1 (https=)
EP (1) EP3914616A1 (https=)
JP (1) JP2022523047A (https=)
KR (1) KR20210119448A (https=)
CN (1) CN113614107A (https=)
AU (1) AU2020211728A1 (https=)
BR (1) BR112021014574A2 (https=)
CA (1) CA3127520A1 (https=)
IL (1) IL284962A (https=)
MX (1) MX2021008672A (https=)
SG (1) SG11202107941TA (https=)
WO (1) WO2020152290A1 (https=)
ZA (1) ZA202105154B (https=)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3943505A1 (en) 2020-07-22 2022-01-26 Encefa Cd38-binding cd31 peptides and uses thereof
CN117567594B (zh) * 2023-11-30 2025-02-07 北京博奥森生物技术有限公司 一种模拟cd31线性分子抗原性的分支多肽制备方法

Family Cites Families (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4816567A (en) 1983-04-08 1989-03-28 Genentech, Inc. Recombinant immunoglobin preparations
IL85035A0 (en) 1987-01-08 1988-06-30 Int Genetic Eng Polynucleotide molecule,a chimeric antibody with specificity for human b cell surface antigen,a process for the preparation and methods utilizing the same
DE69120146T2 (de) 1990-01-12 1996-12-12 Cell Genesys Inc Erzeugung xenogener antikörper
US6673986B1 (en) 1990-01-12 2004-01-06 Abgenix, Inc. Generation of xenogeneic antibodies
US6150584A (en) 1990-01-12 2000-11-21 Abgenix, Inc. Human antibodies derived from immunized xenomice
US6075181A (en) 1990-01-12 2000-06-13 Abgenix, Inc. Human antibodies derived from immunized xenomice
EP1400536A1 (en) 1991-06-14 2004-03-24 Genentech Inc. Method for making humanized antibodies
DE19742706B4 (de) 1997-09-26 2013-07-25 Pieris Proteolab Ag Lipocalinmuteine
ATE375365T1 (de) 1998-04-02 2007-10-15 Genentech Inc Antikörper varianten und fragmente davon
PL209392B1 (pl) 1999-01-15 2011-08-31 Genentech Inc Przeciwciało, komórka gospodarza, sposób wytwarzania przeciwciała oraz zastosowanie przeciwciała
CA2704600C (en) 1999-04-09 2016-10-25 Kyowa Kirin Co., Ltd. A method for producing antibodies with increased adcc activity
FR2807767B1 (fr) 2000-04-12 2005-01-14 Lab Francais Du Fractionnement Anticorps monoclonaux anti-d
CA2430013C (en) 2000-11-30 2011-11-22 Medarex, Inc. Transgenic transchromosomal rodents for making human antibodies
US7083784B2 (en) 2000-12-12 2006-08-01 Medimmune, Inc. Molecules with extended half-lives, compositions and uses thereof
US20040002587A1 (en) 2002-02-20 2004-01-01 Watkins Jeffry D. Fc region variants
EP1553975B8 (en) 2002-09-27 2023-04-12 Xencor, Inc. Optimized fc variants and methods for their generation
CA2512729C (en) 2003-01-09 2014-09-16 Macrogenics, Inc. Identification and engineering of antibodies with variant fc regions and methods of using same
CA2625681C (en) * 2005-10-12 2016-08-02 Morphosys Ag Generation and profiling of fully human hucal gold-derived therapeutic antibodies specific for human cd38
KR20140133958A (ko) 2005-10-21 2014-11-20 엘에프비 유에스에이, 인크. 항체 의존성 세포 독성 활성이 증강된 항체, 그 생산 및 사용 방법
EP1930342B1 (en) 2006-12-04 2012-01-25 Institut Pasteur OB-fold used as scaffold for engineering new specific binders
PL2602323T3 (pl) 2007-06-01 2018-06-29 Open Monoclonal Technology, Inc. Kompozycje i sposoby hamowania endogennych genów immunoglobin i wytwarzania transgenicznych ludzkich przeciwciał typu idiotypowego
JP5913980B2 (ja) 2008-10-14 2016-05-11 ジェネンテック, インコーポレイテッド 免疫グロブリン変異体及びその用途
EP2233500A1 (en) 2009-03-20 2010-09-29 LFB Biotechnologies Optimized Fc variants
US20120258496A1 (en) 2010-09-27 2012-10-11 Boehringer Ingelheim International Gmbh Production of low fucose antibodies in h4-ii-e rat cells
JOP20210044A1 (ar) * 2010-12-30 2017-06-16 Takeda Pharmaceuticals Co الأجسام المضادة لـ cd38
FR3003171B1 (fr) 2013-03-15 2015-04-10 Lab Francais Du Fractionnement Nouveaux medicaments comprenant une composition d'anticorps enrichie en isoforme de charge majoritaire
US20150093399A1 (en) 2013-08-28 2015-04-02 Bioasis Technologies, Inc. Cns-targeted conjugates having modified fc regions and methods of use thereof
MA40894A (fr) * 2014-11-04 2017-09-12 Glenmark Pharmaceuticals Sa Immunoglobulines hétéro-dimères reciblant des lymphocytes t cd3/cd38 et leurs procédés de production
EA039366B1 (ru) 2015-06-24 2022-01-19 Джей Си Ар ФАРМАСЬЮТИКАЛЗ КО., ЛТД. Антитело к рецептору трансферрина человека, проникающее через гематоэнцефалический барьер
CN110997722B (zh) * 2017-06-08 2023-09-26 黑带医疗有限公司 Cd38调节抗体

Similar Documents

Publication Publication Date Title
JP7027482B2 (ja) Gタンパク質共役受容体を標的化する抗体および使用の方法
JP7823118B2 (ja) α-シヌクレインに対する抗体およびその使用
JP7019198B2 (ja) 補体関連疾患の予防及び治療のためのc5抗体及び方法
WO2021104053A1 (zh) 一种tslp相关病症治疗剂的开发和应用
JP6400480B2 (ja) ペプチドグリカン認識タンパク質1に結合する抗体
JP2018138035A (ja) 静電的ステアリング(electrostatic steering)効果を用いた抗体Fcヘテロ二量体分子を作製するための方法
TW201833141A (zh) 抗b7-h3抗體、其抗原結合片段及其醫藥用途
CN111320693B (zh) 抗EphA4抗体
RU2004121673A (ru) Человеческие полипептиды, вызывающие или опосредующие лизис клеток, включая клетки лимфоидных опухолей
CN113906050B (zh) 抗EphA4抗体
KR20120056800A (ko) 글루글루카곤 수용체에 대한 항체와 이의 사용
WO2019228405A1 (zh) 一种自免疫抑制剂及其应用
JP2022542884A5 (https=)
JP2025134864A5 (https=)
JP2022523047A5 (https=)
WO2016119523A1 (zh) 全人源her2抗体的突变抗体及其编码基因和应用
RU2021124077A (ru) Конкурент за связывание с антителом CD31 и его применение
JP7839108B2 (ja) 筋萎縮性側索硬化症の治療用医薬組成物
JP7796049B2 (ja) 抗EphA4抗体
RU2816371C2 (ru) АНТИТЕЛО К EphA4
TW202328194A (zh) Lilrb2特異性單株抗體及其使用方法
KR20100021657A (ko) 프로테아제 활성화된 수용체-1 (par1)의 길항제 항체
JP2024541576A (ja) 新規特異的アンタゴニスト抗SIRPg抗体
HK40105878A (zh) 新的抗masp-2抗体
CN119585311A (zh) 结合大麻素受体cb1的抗体及其用途