JP2022520716A - 複数の低次元血管造影投影からの移動血管脈波の時空間的再構成 - Google Patents
複数の低次元血管造影投影からの移動血管脈波の時空間的再構成 Download PDFInfo
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Abstract
Description
本出願は、2019年2月6日に出願された仮特許出願第62/801766号に対して米国特許法119条の下、優先権を主張し、参照によりその全体が本出願に組み込まれる。
角度θ1、角度θ2、角度θNに対応するシーケンスは、3Dの高次物体を生成するために、逆ペンローズ変換(例えば、図3(a),(b)と同様)を使用して処理され得る。例えば、角度θ1、角度θ2、角度θNに対応するフレームを(任意の時点での決定された角度について)逆ペンローズ変換を使用して処理することができるように、フレームの各セットについて処理を繰り返すことができる。ここで、心臓周波数血管造影現象を含む各シーケンスは、例えば、心臓周波数血管造影現象の位相および/または大きさに基づいて同期されているものと仮定される。いくつかの態様では、補間は、心臓周波数血管造影現象のシーケンスを整列させるときに使用され得る。したがって、これらの技術は、時間の関数として3D血管脈波の可視化を提供する。
ここで、相関関数は次の通りである
Claims (18)
- 再構成された時空間的心臓周波数現象の複数の低次元の同期された投影から時空間的心臓周波数現象のより高次の画像表示を再構成するための方法であって、
前記再構成は、血管造影現象の時空間的再構成における心臓周波数での生理学的コヒーレンスと前記投影において行われる複素数値による方法とを使用して実行される、方法。 - 血管造影法を用いて得られた複数の低次元画像投影から時空間的心臓周波数現象のより高い次元空間表現を再構成するための方法であって、
心臓の周波数よりも速い速度で物体の複数の画像投影のシーケンスを取得することと、
前記複数のシーケンスの各々を独立して処理して、心臓周波数血管造影現象に対応する複数のシーケンスを取得することと、
生理学的コヒーレンスを使用して、心臓周波数血管造影現象に対応する前記複数のシーケンスを同期させることと、
前記同期された複数のシーケンスを複素数値による方法で処理して、前記心臓周波数血管造影現象のより高いレベルの空間的再構成を生成することを含む方法。 - 前記複素数値による方法は、逆ペンローズ変換である、請求項2に記載の方法。
- 前記シーケンスがまばらなデータを含む、請求項2に記載の方法。
- 前記まばらなデータの処理を補足するために、補間が使用される、請求項4に記載の方法。
- 血管造影のタイプが、平行ビーム形状、ファンビーム形状、またはコーンビーム形状を含む、請求項2に記載の方法。
- 前記複数のシーケンスが、指標源を参照して得られる、請求項2に記載の方法。
- 前記指標源が、生理学的マーカー、パルスオキシメータ、心電図、または頭蓋内圧波形から得られる、請求項7に記載の方法。
- 複数の2D画像投影から3D再構成が生成されるか、または複数の1D画像投影から2D再構成が生成される、請求項2に記載の方法。
- 別々の投影の各々における移動血管脈波を同期させるための方法であって、再構成された時空間的心臓周波数現象の別々の投影を同期させるために、心臓周波数で血管造影コヒーレンスを使用することを含む方法。
- バイプレーンデータから心臓周波数血管造影現象のより高次の表現を再構成するための方法であって、
血管造影データが同じ時点で得られた3D物体の2D画像投影の2つのシーケンス(第1のシーケンスおよび第2のシーケンス)を含み、前記シーケンスが心臓周波数よりも速い速度で取得される、前記血管造影データを取得することと、
各シーケンスを独立して処理して時空間的心臓周波数現象を取得することと、
フレームごとに、第1の投影と第2の投影とを、容積空間において互いに直交して位置させて、第1の軸に沿って前記第1の投影を投影させると共に、第2の軸に沿って前記第2の投影を投影させることと、
交差するボクセルに対して、閾値よりも大きいコヒーレンス値を有するボクセルが保持されるようにボクセルをフィルタ処理することと、
前記フィルタ処理されたボクセルに基づいて前記時空間的心臓周波数現象の3D再構成を生成することと、を含む方法。 - 前記第1のシーケンスを、SI次元に対して前記第2のシーケンスと整列させるために、前記第1のシーケンスを変位させることを含む、請求項11に記載の方法。
- フィルタ処理が、閾値未満のコヒーレンス値を有するボクセルを除去することをさらに含む、請求項11に記載の方法。
- 3D空間内で第1及び第2のシーケンスを整列させるために、画像投影の前記第1及び/又は第2のシーケンスを転置することを含む、請求項11に記載の方法。
- 前記コヒーレンス値は、前記交差するボクセルが同じ血管に対応することを示す閾値に設定される、請求項11に記載の方法。
- 前記第1の軸および前記第2の軸は、互いに直交している、請求項11に記載の方法。
- 血管造影のためのコンピュータシステムであって、
1つ以上のコンピュータプロセッサと、
1つ以上のコンピュータ可読記憶媒体と、
前記1つ以上のコンピュータプロセッサによる実行のために、前記1つ以上のコンピュータ可読記憶媒体に記憶されると共に、請求項1~16のいずれか1つ又は複数に従った方法を行うための実行可能な命令を含むプログラム命令と、を含むコンピュータシステム。 - 請求項1~16のいずれか又は複数の方法を行うための命令を処理させるコンピュータによりプログラム命令が実行可能であり、具現化された前記プログラム命令を有するコンピュータ可読記憶媒体を含む血管造影用のコンピュータプログラム製品。
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