JP2022520050A - 干渉が低減されたアッセイ（ｉｉｉ） - Google Patents

干渉が低減されたアッセイ（ｉｉｉ） Download PDF

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JP2022520050A
JP2022520050A JP2021545856A JP2021545856A JP2022520050A JP 2022520050 A JP2022520050 A JP 2022520050A JP 2021545856 A JP2021545856 A JP 2021545856A JP 2021545856 A JP2021545856 A JP 2021545856A JP 2022520050 A JP2022520050 A JP 2022520050A
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スティーブン ワイ． チョウ
ウェイ ディン
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エッセンリックス コーポレーション
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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54366—Apparatus specially adapted for solid-phase testing
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/6428—Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes"
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/75—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated
    • G01N21/77—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/5306—Improving reaction conditions, e.g. reduction of non-specific binding, promotion of specific binding
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/66—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood sugars, e.g. galactose
    • G—PHYSICS
    • G06—COMPUTING OR CALCULATING; COUNTING
    • G06V—IMAGE OR VIDEO RECOGNITION OR UNDERSTANDING
    • G06V10/00—Arrangements for image or video recognition or understanding
    • G06V10/70—Arrangements for image or video recognition or understanding using pattern recognition or machine learning
    • G06V10/77—Processing image or video features in feature spaces; using data integration or data reduction, e.g. principal component analysis [PCA] or independent component analysis [ICA] or self-organising maps [SOM]; Blind source separation
    • G06V10/774—Generating sets of training patterns; Bootstrap methods, e.g. bagging or boosting
    • G—PHYSICS
    • G06—COMPUTING OR CALCULATING; COUNTING
    • G06V—IMAGE OR VIDEO RECOGNITION OR UNDERSTANDING
    • G06V20/00—Scenes; Scene-specific elements
    • G06V20/60—Type of objects
    • G06V20/69—Microscopic objects, e.g. biological cells or cellular parts
    • G06V20/693—Acquisition
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/6428—Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes"
    • G01N2021/6439—Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes" with indicators, stains, dyes, tags, labels, marks
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/75—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated
    • G01N21/77—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator
    • G01N2021/7769—Measurement method of reaction-produced change in sensor
    • G01N2021/7786—Fluorescence
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/75—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated
    • G01N21/77—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator
    • G01N21/78—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator producing a change of colour
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/483—Physical analysis of biological material
    • G01N33/487—Physical analysis of biological material of liquid biological material

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  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Chemical & Material Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Urology & Nephrology (AREA)
  • Biochemistry (AREA)
  • Pathology (AREA)
  • Analytical Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Theoretical Computer Science (AREA)
  • Multimedia (AREA)
  • Databases & Information Systems (AREA)
  • Artificial Intelligence (AREA)
  • Optics & Photonics (AREA)
  • Software Systems (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medical Informatics (AREA)
  • Evolutionary Computation (AREA)
  • Computing Systems (AREA)
  • Computer Vision & Pattern Recognition (AREA)
  • Plasma & Fusion (AREA)
  • Diabetes (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
JP2021545856A 2019-02-06 2020-02-06 干渉が低減されたアッセイ（ｉｉｉ） Pending JP2022520050A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201962802172P 2019-02-06 2019-02-06
US62/802,172 2019-02-06
PCT/US2020/017100 WO2020163658A1 (en) 2019-02-06 2020-02-06 Assays with reduced interference (iii)

Publications (2)

Publication Number Publication Date
JP2022520050A true JP2022520050A (ja) 2022-03-28
JP2022520050A5 JP2022520050A5 (https=) 2023-02-06

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JP2021545856A Pending JP2022520050A (ja) 2019-02-06 2020-02-06 干渉が低減されたアッセイ（ｉｉｉ）

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US (1) US20220137038A1 (https=)
EP (1) EP3906411A4 (https=)
JP (1) JP2022520050A (https=)
CN (1) CN114174824A (https=)
WO (1) WO2020163658A1 (https=)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2021195614A1 (en) * 2020-03-27 2021-09-30 Salvus, Llc System and method for analyte detection and decontamination certification
US11853013B2 (en) * 2020-06-15 2023-12-26 Johnson & Johnson Vision Care, Inc. Systems and methods for indicating the time elapsed since the occurrence of a triggering event
US20230408534A1 (en) * 2020-10-08 2023-12-21 Essenlix Corporation Assay Error Reduction

Citations (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH11352411A (ja) * 1998-05-27 1999-12-24 Becton Dickinson & Co 顕微鏡分析用の薄い液体試料を生成する装置
WO2002023154A2 (en) * 2000-09-13 2002-03-21 Biometric Imaging, Inc. Aggregation-based assays
JP2002516982A (ja) * 1998-03-07 2002-06-11 ウォードロウ、スチーブン、シー 抗凝固全血静止サンプルの分析
JP2006071475A (ja) * 2004-09-02 2006-03-16 Hakuju Inst For Health Science Co Ltd 血液観察用試料台、及び血液細胞の分離定量評価方法
JP2011515681A (ja) * 2008-03-21 2011-05-19 アボット ポイント オブ ケア インコーポレイテッド 赤血球中に含まれるヘモグロビンの固有色素を利用して血液試料のヘマトクリットを測定する方法及び装置
JP2012247205A (ja) * 2011-05-25 2012-12-13 Konica Minolta Advanced Layers Inc 血液検査装置
JP2015522825A (ja) * 2012-07-18 2015-08-06 セラノス， インコーポレイテッド 凝集の検出および測定のための方法
US20160291015A1 (en) * 2015-03-31 2016-10-06 Commissariat A L'energie Atomique Et Aux Energies Alternatives Method for determining the level of agglutination of particles in a sample
US20170268989A1 (en) * 2016-03-17 2017-09-21 Commissariat A L'energie Atomique Et Aux Energies Alternatives Method for characterizing a liquid sample containing particles
JP2018517209A (ja) * 2015-05-28 2018-06-28 トキタエ エルエルシー 画像分析システムおよび関連する方法
JP2018532998A (ja) * 2015-09-14 2018-11-08 エッセンリックス コーポレーション 試料、特に血液を分析するための装置及びシステム、並びにそれらの使用方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4925703B2 (ja) * 2006-03-30 2012-05-09 シスメックス株式会社 血液凝固分析装置
CA2855363C (en) * 2011-11-10 2019-02-12 The Administrators Of The Tulane Educational Fund Paper based diagnostic test
KR101352849B1 (ko) * 2012-01-03 2014-01-21 주식회사 나노엔텍 멀티머-형성 폴리펩타이드의 멀티머형을 분별 검출하는 방법
JP6416135B2 (ja) * 2013-03-15 2018-10-31 ベンタナ メディカル システムズ， インコーポレイテッド スペクトル・アンミキシング
CN113376364B (zh) * 2015-08-10 2025-02-25 上海宜晟生物科技有限公司 步骤简化、小样品、快速、易使用的生物/化学分析装置和方法
US20200333322A1 (en) * 2017-07-31 2020-10-22 Essenlix Corporation Assays with reduced interference

Patent Citations (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2002516982A (ja) * 1998-03-07 2002-06-11 ウォードロウ、スチーブン、シー 抗凝固全血静止サンプルの分析
JPH11352411A (ja) * 1998-05-27 1999-12-24 Becton Dickinson & Co 顕微鏡分析用の薄い液体試料を生成する装置
WO2002023154A2 (en) * 2000-09-13 2002-03-21 Biometric Imaging, Inc. Aggregation-based assays
JP2006071475A (ja) * 2004-09-02 2006-03-16 Hakuju Inst For Health Science Co Ltd 血液観察用試料台、及び血液細胞の分離定量評価方法
JP2011515681A (ja) * 2008-03-21 2011-05-19 アボット ポイント オブ ケア インコーポレイテッド 赤血球中に含まれるヘモグロビンの固有色素を利用して血液試料のヘマトクリットを測定する方法及び装置
JP2012247205A (ja) * 2011-05-25 2012-12-13 Konica Minolta Advanced Layers Inc 血液検査装置
JP2015522825A (ja) * 2012-07-18 2015-08-06 セラノス， インコーポレイテッド 凝集の検出および測定のための方法
US20160291015A1 (en) * 2015-03-31 2016-10-06 Commissariat A L'energie Atomique Et Aux Energies Alternatives Method for determining the level of agglutination of particles in a sample
JP2018517209A (ja) * 2015-05-28 2018-06-28 トキタエ エルエルシー 画像分析システムおよび関連する方法
JP2018532998A (ja) * 2015-09-14 2018-11-08 エッセンリックス コーポレーション 試料、特に血液を分析するための装置及びシステム、並びにそれらの使用方法
US20170268989A1 (en) * 2016-03-17 2017-09-21 Commissariat A L'energie Atomique Et Aux Energies Alternatives Method for characterizing a liquid sample containing particles

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EP3906411A4 (en) 2023-01-18
EP3906411A1 (en) 2021-11-10
WO2020163658A1 (en) 2020-08-13
US20220137038A1 (en) 2022-05-05
CN114174824A (zh) 2022-03-11

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